혈청 펩시노겐치를 이용한 위암 및 위선종의 집단검진

김장락,최진학,김영채,이옥재,조규일,이한우,홍대용,Kim, Jang-Rak,Choi, Jin-Hak,Kim, Young-Chai,Lee, Ok-Jae,Cho, Kyu-Il,Lee, Han-Woo,Hong, Dae-Yong 대한예방의학회 1994 예방의학회지 Vol.27 No.4

To evaluate the validity of serum pepsinogen levels as a screening tool for gastric cancer and adenoma, immunoradiometric assays of serum pepsinogen I level (PG I), II level (PG II) and esphagogastroduodenal endoscopies were done in 757 health examinees. Serum PG I level was higher in subjects with active duodenal ulcer (n=45, $75.2{\pm}34.3{\mu}g/l(mean{\pm}standard\;deviation)$, p<0.01) and gastroduodenal ulcers (n=8, $75.6{\pm}19.8{\mu}g/l$, p<0.05), and was lower in those with gastric adenoma(n=4, $37.7{\pm}37.2{\mu}g/l$, p<0.2) than those with normal, mild gastritis findings or ulcer scars (n=378, $56.6{\pm}24.9{\mu}g/l$. Serum PG II level was higher in subjects with active duodenal ulcer($17.2{\pm}13.8{\mu}g/l$, p<0.2), active gastro-duodenal ulcers ($18.3{\pm}7.4{\mu}g/l$, p<0.2) and gastric carcinoma (n=3, $23.8{\pm}10.9{\mu}g/l$, p<0.05) than those with normal, mild gastritis findings or ulcer scars $(14.5{\pm}7.9{\mu}g/l)$. Serum PG I/PG II ratio was higher in subjects with active duodenal ulcer($5.1{\pm}1.6$, p<0.05) and was lower in those with chronic gastritis(n=107, $4.1{\pm}1.7$, p<0.05), gastric polyp(n=19, $3.9{\pm}1.4$, p<0.2), gastric adenoma(n=4, $2.1{\pm}1.9$, p<0.01) and gastric carcinoma(n=3, $2.7{\pm}1.2$, p<0.1) than those with normal, mild gastritis findings or ulcer scars ($4.5{\pm}1.7$). Serum PG II level increased with age until 6th decade, whereas serum PG I/PG II ratio decreased with age in 378 subjects with normal, mild gastritis findings or ulcer scars. The screening criteria of serum PG I<$70{\mu}g/l$ and PG I/PG II ratio<3.0 for detecting gastric cancer and adenoma gave a positive rate of 15.7%, sensitivity of 57.1% and specificity of 84.7%.

Individual-level Associations Between Indicators of Social Capital and Alcohol Use Disorders Identification Test Scores in Communities With High Mortality in Korea

김장락,정백근,박기수,강윤식 대한예방의학회 2020 예방의학회지 Vol.53 No.4

Objectives: This study examined associations among social capital indicators (social participation and generalized trust) at the individual level and alcohol use, which was quantified using Alcohol Use Disorders Identification Test (AUDIT) scores. Methods: In total, there were 8800 participants in community health interviews, including 220 adults sampled systematically from a resident registration database of each of 40 sub-municipal administrative units of local (city or county) governments. Adjusted odds ratios (aORs) and 95% confidence intervals (CIs) were calculated using polychotomous logistic regression. Results: The aORs for abstainers versus people with AUDIT scores of 0-7, based on 3 questions on generalized trust, in comparison to those with no positive responses, were 1.15 (95% CI, 0.99 to 1.34) for 1 positive response, 1.16 (95% CI, 0.98 to 1.37) for 2 positive responses; and 1.39 (95% CI, 1.20 to 1.61) for 3 positive responses. The aORs for abstainers versus people with AUDIT scores of 0-7, in comparison to participation in no organizations, were 0.61 (95% CI, 0.54 to 0.69) for participation only in informal organizations; 2.16 (95% CI, 1.57 to 2.99) for participation only in religious organizations; 2.41 (95% CI, 1.10 to 5.29) for participation only in volunteer organizations; and 0.65 (95% CI, 0.57 to 0.74) for participation in formal organizations. Participants in formal social organizations, regardless of their participation in informal organizations, were more likely to have AUDIT scores of 8-15 (aOR, 1.29; 95% CI, 1.04 to 1.60) or ≥16 (aOR, 1.65; 95% CI, 1.22 to 2.23) than to have scores of 0-7. Conclusions: Our findings may have implications for health policy to reduce alcohol problems.

중년 남성 근로자에서 신체 적합도, 여가중 신체 활동과 혈중 지질 농도

김장락,남복동,김주호,이송권,문중갑,이장호,홍대용,Kim, Jang-Rak,Nam, Bock-Dong,Kim, Ju-Ho,Lee, Song-Kwon,Moon, Joong-Kap,Lee, Jang-Ho,Hong, Dae-Yong 대한예방의학회 1996 예방의학회지 Vol.29 No.2

This is a cross-sectional study to evaluate the relationships between physical fitness, leisure time physical activity, and serum lipid levels in middle-aged male workers. Physical fitness was measured by a step test score, and leisure time physical activity was self-reported on a questionnaire. Serum total cholesterol was negatively related to physical fitness(r=-0.27), and positively to obesity index(r=0.27). But leisure time physical activity was related to total cholesterol negatively(r=-0.20) only in subjects whose total cholesterol levels were above 170mg/dl. High density lipoprotein(HDL) cholesterol was positively related to physical fitness(r=0.15), negatively to obestiy index(r=-0.22), and positively to weekly alcohol consumption(r=0.14). Total cholesterol/HDL cholesterol ratio was related to physical fitness(r=-0.23), obesity index(r=0.32), total cigarette index (r=0.13), weekly alcohol consumption(r=-0.13), and vegetable preference(r=0.13). Physical fitness was also related to leisure time physical activity(r=0.19) and obesity index(r=-0.18). In multiple linear regression models, physical fitness(beta=-0.23) and obesity index(beta=0.18) were significantly associated with total cholesterol, obesity index(beta=-0.25) with HDLcholesterol, and obesity index(beta=0.30), physical fitness(beta=-0.16) and vegetable preference (beta=0.14) with total cholesterol/HDL cholesterol ratio. In conclusion, as physical fitness has a stronger relationship with serum lipid levels than leisure time physical activity, and the association between physical fitness and leisure time physical activity is modest, physical fitness should be added as an important variable in addition to activity in future epidemiologic studies.

뇌혈관질환의 위험요인에 대한 환자 - 대조군 연구

김장락,홍대용,박성학,Kim, Jang-Rak,Hong, Dae-Yong,Park, Sung-Hak 대한예방의학회 1995 예방의학회지 Vol.28 No.2

A hospital-based, matched case-control study was carried out to evaluate the relation ship of various suspected risk factors including snoring and serum level of cholesterol to cerebrovascular disease in Korea. A total of 127 incident cases of cerebrovascular disease(74 cases of cerebral infarction and 53 cases of intracerebral hemorrhage) admitted to. the department of neurology in a university hospital from December, 1993 to March, 1995 were compared with 127 matched controls admitted to same hospital in same period. A multivariate analysis suggested that ECG abnormality(left ventricular hypertrophy and atrial fibrillation), family history of cerebrovascular disease, fundoscopic abnormality, previous history of transient ischemic attack and hypercholesterolemia were risk factors of cerebrovascular disease, ECG abnormality, fundoscopic abnormality, smoking and hypercholesterolemia were also suggested as risk factors of cerebral infarction.

도로 포장관리체계(PMS)의 확대운영

김장락,조남근,박형군,김종호,문형철 한국도로학회 2018 한국도로학회지 Vol.20 No.1

양생제가 콘크리트포장의 초기 거동에 미치는 영향에 관한 연구

김장락,서영찬,안성순,김형배,김종호 한국도로학회 2003 한국도로학회 학술대회 발표논문 초록집 Vol.2003 No.10

도심지 도로에서 관성형 프로파일러로 측정된 종단평탄성의 보정방안 연구

김장락,조남근,양명준,김원재 한국도로학회 2023 한국도로학회 학술대회 발표논문 초록집 Vol.2023 No.10

경남 일부 지역 초, 중, 고등학생의 비만율과 관련요인

김장락,강윤식,정백근,김성희,김병로,박기수,홍대용 한국모자보건학회 2007 한국모자보건학회지 Vol.11 No.1

Objectives: This study was conducted to estimate the prevalence of obesity and identify obesity-related factors among elementary, junior high, and senior high school students in Gyeongnam Province. Methods: The study subjects were total 1,704 students (896 male and 808 female students) from 53 classes among arbitrarily selected 13 elementary (4th grade or above), junior high, or senior high schools in one county area, one small city, and one medium-sized city in Gyeongnam Province. We used height and weight information measured and recorded in physical examinations in the 1st semester to calculate the degree of obesity according to 1998 year Korean standard body weight published by Korean Society for Pediatrics. Obesity was defined as ≥120% of standard body weight. Information on the students' dietary habit and physical activities was collected with self-administered questionnaires in the 2nd semester. Results: The prevalence of obesity was 12.4% for male and 9.3% for female students (p<0.05). As the grade became higher, the prevalence had tendency to become higher. The significant obesity-related factors in the logistic regression analysis were 'eating amount and speed compared with friends' and 'frequency of eating ramyon' among male students; 'perceived obesity of parents', 'eating amount and speed compared with friends'. 'frequency of moderate or vigorous activities’, and 'fish preference' among female students Conclusions: This study suggested that 'eating amount and speed' and 'perceived obesity of parents' were risk factors for obesity for students. Obese students seemed to eat less ramyon in boys and do more moderate or vigorous activities in girls. However, a prospective follow-up study is warranted to identify exact risk factors for obesity among students in Korea.

농촌지역 모성의 산전관리서비스 이용양상과 그 결정요인

김장락,박정한,이재경,서상홍,방준용,Kim, Jang-Rak,Park, Jung-Han,Lee, Jae-Kyong,Seo, Sang-Hong,Bang, Joon-Yong 대한예방의학회 1993 예방의학회지 Vol.26 No.4

To study the pattern of prenatal care utilization and its determinants in rural Korea, 976 mothers (65.5%) out of 1,489 living mothers in Chinyang, Sachon and Hapchon Counties in Kyongsangnam Province who had delivered a baby between July 1, 1990 and June 30, 1991 were interviewed by the Myon health workers from January 3 through February 15, 1992. The Anderson's behavioral model for health service utilization was applied to develop the frames for analysis. The dependent variable was a number of prenatal care visits. And the independent variables included In the model were the variables pertaining to the predisposing, enabling, medical need and other components. The proportion of mother who had ever received the prenatal care service for the index pregnancy was 97.3%. However, the proportion of mothers who had made more than 10 visits was only 20.6%, which indicated that majority of mothers had paid far less visits than recommended $10{\sim}12$ visits for each normal pregnancy. The low utilization of prenatal care services (none or less than 4 visits) was related to mother's low educational level, the high birth order, beneficiary of the medical aid, the absence of clinic in the community, no diagnosed disease of mother during pregnancy, and mothers engaged in farming. Inequity of access seemed to exist because social structure variables and the variables of enabling component were important predictors. And there seemed to be high mutability in equalizing the distribution of prenatal care services because the variables of enabling component such as type of medical security and whether there was a clinic or not in the community were substantially important.

고혈암의 치료순응과 그 관련요인에 대한 지역사회 추적조사

김장락,문중갑,강경희,이명순,홍대용 ( Jang Rak Kim,Joong Kap Moon,Kyoung Heui Kang,Myoung Soon Lee,Dae Yong Hong _ 대한보건협회 1997 대한보건연구 Vol.23 No.1