한국인의 Epstein-Barr Virus 항체 양성률 변화양상에 대한 분석: 단일기관 연구

김수경,최준식,김동섭,강철인,정두련,백경란,강은숙,김예진,Kim, Su Kyung,Choi, Joon-Sik,Kim, Dongsub,Kang, Cheol-In,Chung, Doo Ryeon,Peck, Kyong Ran,Kang, Eun-Suk,Kim, Yae-Jean 대한소아감염학회 2020 Pediatric Infection and Vaccine Vol.27 No.2

Purpose: Epstein-Barr virus (EBV) infection is related to infectious mononucleosis or nasopharyngeal cancer, and its epidemiology may change according to the socioeconomic development of communities. This study aimed to evaluate the recent epidemiology of EBV seropositive rate in Korea. Methods: We retrospectively reviewed EBV serology test results obtained from a part of clinical care at Samsung Medical Center, Seoul, South Korea, from January 2000 to December 2017. Results: The EBV seropositive rate in 26,527 subjects during the study period was 81.0% (21,485/26,527): 44.4% (2,716/6,122) in subjects aged 0-9 years, 75.8% (2,077/2,739) in those aged 10-19 years, and 94.5% (16,692/17,666) in those aged ≥20 years. The EBV seropositive rate decreased from 89.4% (8,592/9,616) in 2000-2008 to 76.2% (12,893/16,911) in 2009-2017 (P<0.001). Especially, the EBV seropositive rate in subjects aged 0-19 years significantly decreased from 2000-2008 to 2009-2017 (0-9 years, 62.8% [1,172/1,866] in 2000-2008 and 36.3% [1,544/4,256] in 2009-2017; 10-19 years, 83.8% [745/858] in 2000-2008 and 70.8% (1,332/1,881) in 2009-2017) (P<0.001). Conclusions: The EBV seropositive rate in children has decreased in the last 20 years. As the age of patients with primary EBV infection increased, there is a need for interest in clinical manifestation, such as infectious mononucleosis, in adolescents and young adults.

백서두개골 결손부에서 키토산/흡수성 콜라겐 전달체의 골재생

김수경,석헌주,김창성,조규성,채중규,김종관,최성호,Kim, Soo-Kyoung,Suk, Hun-Joo,Kim, Chang-Sung,Cho, Kyoo-Sung,Chai, Jung-Kiu,Kim, Chong-Kwan,Choi, Seong-Ho 대한치주과학회 2003 Journal of Periodontal & Implant Science Vol.33 No.3

The ultimate objective of periodontal treatment is to get rid of an on-going periodontal disease and further regenerate the supporting tissue, which is already destroyed, functionally. Currently, the bone grafting operation using various kinds of bone grafting materials and the operation for induced regeneration of periodontal tissue using the blocking membrane are performed for regeneration of the destroyed periodontal tissue. However, there are respective limitations Galenical preparations, which are used for regeneration of periodontal of tissue, has less risk of rejective reaction or toxicity that may be incidental to degradation and their effect is sustainable. Thus, in case they are applicable to a clinic, they can he used economically. Chitosan has such compatibility, biological actions including antibacterial activity, acceleration of wound treatment, etc., and excellent mechanical characteristics, which has recently aroused more interest in it. Also, it has been reported that it promotes osteogenesis directly or indirectly by functioning as a matrix to promote migration and differentiation of a specific precussor cell (for example, osteoblast) and further inhibiting the function of such a cell as fibroblast to prevent osteogenesis. In this study, the pure chitosan solution, which was obtained by purifying chitosan, was used. However, since this chitosan is of a liquiform, it is difficult to sustain it in a defective region. It is, therefore, essential to use a carrier for delivering chitosan to, and sustaining it gradually in the defective region. In the calvarial defect model of the Sprague-Dawley rat, it is relatively easy to maintain a space. Therefore, in this study, the chitosan solution with which ACS was wetted was grafted onto the defective region, For an experimental model, a calvarial defect of rat m s selected, and a critical size of the defective region was a circular defect with a diameter of 8 mm. A group in which no treatment was conducted for the calvarial defect was set as a negative control group. Another group in which treatment was conducted with ACS only was set as a positive control group (ACS group). And another group in which treatment was conducted was conducted with by grafting the pure chitosan solution onto the defective region through ACS which was wetted with the chitosan solution was set an experimental group (Chitosan/ACS group). Chitosan was applied to the Sprague-Dawley rat's calvarial bone by applying ACS which was wetted with the chitosan solution, and each Sprague-Dawley rat was sacrificed respectively 2 weeks and 8 weeks after the operation for such application. Then, the treatment results were compared and observed histologically and his tometrically. Thereby, the following conclusions were obtained. 1. In the experimental group, a pattern was shown that from 2 weeks after the operation, vascular proliferation proceeded and osteogenesis proceeded through osteoblast infiltration, and at 8 week after the operation, ACS was almost absorbed, the amount of osteogensis was increased and many osteoid tissue layers were observed. 2. At 2 weeks after the operation, each amount of osteogenesis appeared to be 8.70.8 %, 13.62.3 % and 4.80.7 % respectively in the experimental group, the positive control group and the negative control group. Accordingly, it appeared to be higher in the Experimental group and the positive control group than in the negative control group, but there was no significant difference statistically (p<0.01). 3. At 8 weeks after the operation, each amount of osteogenesis appeared to be 62.26.1%, 17.42.5 % and 8.21.4 % respectively in the experimental group, the positive control group and the negative control group. Accordingly, it appeared to be substantially higher in the experimental group than in the positive control group and the negative control group, and there was a significant difference statistically (p<0.01). As a result of conducting the experiment, when ACS

성인의 턱관절장애 자각증상에 영향을 미치는 요인

김수경,김소라,김현경,박지수,이유진,조민서,정은서,Kim, Soo-Kyung,Kim, So-Ra,Kim, Hyun-Kyung,Park, Ji-Su,Lee, Yu-Jin,Cho, Min-Seo,Jung, Eun-Seo 한국치위생학회 2017 한국치위생학회지 Vol.17 No.4

Objectives: The purpose of this study is to identify the perceived symptoms of oral and temporomandibular joint disorders in adults and to analyze the factors affecting subjective symptoms of temporomandibular joint disorders. Methods: 249 adults over 20 years old who had subjective symptoms of temporomandibular joint disorders were surveyed and analyzed. Independent t-test and ANOVA test were used to examine the relationship between oral habits and temporomandibular joint disorder according to general characteristics. $Scheff{\acute{e}}$ test was used for post-hoc analysis. Multiple regression analysis was conducted to examine the factors affecting oral habits and temporomandibular joint disorder. Results: First, the factors affecting oral and habitual behaviors were married (p<0.05) and monthly income between 1 million~1.9 million won (p<0.001), higher temporomandibular joint disorder (p<0.01) And the degree of habit was increased. Second, the factors affecting temporomandibular joint disorder were increased in occupation (p<0.05) and the degree of oral habit (p<0.01). Conclusions: In conclusion, it was confirmed that oral habit influences temporomandibular joint disorder. Especially, it is suggested that prevention and promotion of temporomandibular joint disorder are needed to recognize the removal of oral habits.

(정신건강과 자아발달을 돕는) 체험적 독서치료

김수경,Kim, Su-Gyeong 한국도서관협회 2008 圖協會報 Vol.49 No.4

다면적 소셜 IoT 도메인 온톨로지 생성을 위한 온톨로지 스키마 변환 프로세스

김수경,안기홍,김건우,Kim, SuKyung,Ahn, KeeHong,Kim, GunWoo 한국스마트미디어학회 2014 스마트미디어저널 Vol.3 No.3

This research proposes a concept of multi-aspect Social IoT platform that enables human, machine and service to communicate smoothly among them, as well as a means of an automatic process for transforming exiting domain knowledge representation to generic ontology representation used in the platform. Current research focuses on building a machine-based service interoperability using sensor ontology and device ontology. However, to the best of our knowledge, the research on building a semantic model reflecting multi-aspects among human, machine, and service seems to be very insufficient. Therefor, in the research we first build a multi-aspect ontology schema to transform the representation used in each domain as a part of IoT into ontology-based representation, and then develop an automatic process of generating multi-aspect IoT ontology from the domain knowledge based on the schema. 본 연구는 사람, 사물, 그리고 서비스 사이의 통신과 원활한 서비스 운용을 위한 다면적(multi-aspect) Social IoT 플랫폼에 관한 개념을 소개하고, 이러한 다면적 Social IoT 플랫폼상에서 기존 특정 도메인을 위해 구성된 데이터 표현들을 온톨로지 표현으로 재구성할 수 있는 온톨로지 스키마 변환 프로세스들 제안한다. 현재, 많은 연구들이 센서 온톨로지나 디바이스 온톨로지 등과 같이 사물에 기반한 서비스 상호운영성을 위한 인프라 구성에 초점을 둔 표준화된 시맨틱 모델 개발에 집중하고 있으나, 사람과 사물, 그리고 서비스 사이의 최적화된 상호 운용을 위해서는 사람과 사물, 그리고 서비스가 갖는 다양한 특성이 반영된 시맨틱 모델에 관한 연구는 미흡한 실정이다. 따라서, 본 연구에서는 IoT를 구성하는 각 도메인들의 표현 체계를 온톨로지 기반 표현체계로 변환할 수 있도록 기존 소셜 네트워크 구성 요소들을 확장하여 다면적 소셜 네트워크 온톨로지 스키마를 구축하고, 이를 기반으로 IoT내 도메인 지식들을 온톨로지로 자동 변환할 수 있는 프로세스를 개발하였다.

칼럼 - 오리고기를 매일 즐겨먹는 이유와 오리요리법

김수경,Kim, Su-Gyeong 한국오리협회 2013 오리마을 Vol.119 No.-

고등교육재정과 평가 - 새 정부 고등교육재정지원 정책의 방향

김수경,Kim, Su-Gyeong 한국대학교육협의회 2013 大學敎育 Vol.180 No.-

주부를 위한 독서치료 프로그램 운영

김수경,Kim, Soo-Kyoung 한국비블리아학회 2006 한국비블리아학회지 Vol.17 No.1

이 연구에서 주부들의 마음상함을 돌보고 정신건강을 증진하기 위해 공공도서관 기반 발달적 독서치료를 계획하여 운영하였다. 프로그램은 두 가지를 개발하여 운영하였다. 하나는 일반과정 프로그램으로 독서치료에 대한 이해가 전혀 없는 대상에게 적용한 것이고, 다른 하나는 일반과정 수료자중 자신의 상처를 주도적으로 치유하려는 참여자들을 위해 계획한 심화과정 프로그램이다. 이 연구에서는 이 두 가지 프로그램을 운영한 결과, 이에 대한 성과와 개선점에 대해 분석하였다.

독서치료의 힘, 인간띠를 이루다

김수경,김정미,Kim, Su-Gyeong,Kim, Jeong-Mi 한국도서관협회 2005 圖協會報 Vol.46 No.8

세미나 지상중계 - '공부하는 대학총장' 제 1기 대학총장 아카데미 전반부를 마감하며...

김수경,Kim, Su-Gyeong 한국대학교육협의회 2010 大學敎育 Vol.163 No.-