넙치, Paralichthys olivaceus의 미세플라스틱 급성 노출에 따른 혈액성상 및 혈장성분의 변화

김소희,김가현,김지수,김준환,전유현,조재황,김석렬,김대희,Kim, So-Hee,Kim, Ga-Hyun,Kim, Ji-Su,Kim, Jun-Hwan,Jeon, Yu-Hyeon,Cho, Jae-Hwang,Kim, Seok-Ryel,Kim, Dae-Hee 한국환경생물학회 2021 환경생물 : 환경생물학회지 Vol.39 No.3

Juvenile olive flounder, Paralichthys olivaceus (mean weight 66.7±7.1 g; mean length 19.2±0.9 cm) in a bio-floc environment were exposed to microplastic (PE: polyethylene, size 40-48 ㎛) at 0, 4, 20, 100, 500 and 2,500 mg L^-1 for 96 hours. No P. olivaceus deaths were observed following microplastic exposure. In the plasma components, calcium was significantly decreased whereas there was no significant change with magnesium following microplastic exposure. Glucose was significantly decreased with over 100mg L^-1 at 48 hours and 20mg L^-1 at 96 hours. Cholesterol was significantly decreased with over 20mg L^-1 after 48 hours, whereas there was no significant change in the total protein content. In enzymatic plasma components, the AST(Aspartate aminotransferase) was significant decreased by microplastic exposure. The results of this study indicate that acute exposure to microplastic induces blood physiological changes in P. olivaceus.

15년간(1991~2005년) 우리나라 소아에서 분리된 폐구균의 혈청형 분포의 변화

김소희,송은경,이준호,김남희,이진아,최은화,이환종,Kim, So-Hee,Song, Eun-Kyung,Lee, Jun-Ho,Kim, Nam-Hee,Lee, Jin-A,Choi, Eun-Hwa,Lee, Hoan-Jong 대한소아감염학회 2006 Pediatric Infection and Vaccine Vol.13 No.2

목 적 : 폐구균 단백 결합 백신이 개발되었지만 이에 포함되는 혈청형은 7가지로 한정되어 있어, 지역별 주요 폐구균 혈청형의 분포에 따라 백신의 유용성에 차이가 있을 수 있다. 본 연구에서는 우리나라 소아에서 분리된 폐구균의 혈청형의 분포를 분석하고 지난 15년간 시기에 따른 변화 양상을 분석하고자 하였다. 방 법 : 1991년 1월부터 2005년 5월까지 서울대학교 어린이병원 소아 환자의 각종 임상 검체에서 분리된 폐구균 465균주의 혈청형을 quellung reaction으로 결정하였고, penicillin 감수성은 oxacillin 디스크 확산법으로 검사하였다. 연구기간은 1991~1995년(I분기), 1995~2000년(II분기), 2001~2005년(III분기) 등 3개의 분기로 나누어 분석하였다. 결 과 : 465균주의 주된 혈청형은 19F(22%), 23F(18%), 19A(10%), 6B(8%), 14(7%), 6A(7%), 9V(5%) 등이었고, 전체 균주의 79%이었다. 60개월 미만 연령군의 침습성 감염 검체에서 분리된 101균주에서의 주된 혈청형은 혈청형 23F(21%), 14(17%), 19F(15%), 19A(11%), 6B(10%), 6A(7%), 9V(7%) 등으로 총 70%이었다. 전체 균주에서 I, II, III의 각 분기별 혈청형 분포는 백신 혈청형에 포함된 혈청형 19F, 14가 감소하는 추세이었고, 교차 반응 혈청형에 포함된 혈청형 6A, 19A가 증가하는 추세이었다. 침습성 감염 균주에서 폐니실린 내성률은 백신 혈청형에서 92.6%, 교차 반응 혈청형에서 75.0%로 높았으나, 비백신 혈청형에서는 34.4%로 낮았다. 결 론 : 최근 15년간 소아의 임상 검체에서 분리된 폐구균의 혈청형은 주로 19F, 23F, 19A, 6B, 14, 6A, 9V 등이 가장 흔하였고, 최근에 혈청형 19A, 6A가 증가하는 추세이고, 혈청형 19F와 14가 감소하였다. 향후 백신 사용과 관련하여 국내 폐구균 혈청형의 분포에 관한 지속적인 관찰이 필요하다고 생각된다.

우리나라 청소년의 수면시간 및 질과 체질량지수와의 관련성

김소희,김유숙,장영희,박종,류소연,Kim, So-Hui,Kim, Yu-Suk,Jang, Young-Hee,Park, Jong,Ryu, So-Yeon 한국학교보건학회 2012 韓國學校保健學會誌 Vol.25 No.1

Purpose: This study aims to discover the relation between the sleep duration and quality of adolescents and their body mass index. Methods: The study used data obtained through the 2009 online survey on adolescents health behaviors, targeting a total of 75,066 middle and high school students (39,612 of male students and 35,454 of female students). We first performed t-test, ANOVA and Scheffe's test and then the potential variables which was possibly related to the body mass index are determined from the tests. Using the potential variable, we performed the multiple regression analysis to finally identify the relation between the duration and quality of sleep. Results: As a result, the 39.8% of male students and the 46.5% of female students most frequently respond that the sleep duration was less than 6 hours, and 36.4% of male students and the 45.3% of female students respond that the quality of sleep was not good enough. The body mass index of both the male and the female students portionally decreases to their sleep duration, but the better quality of sleep makes their body mass index higher. Conclusion: In conclusion, the body mass index has some notable relationship with the sleep duration and quality for adolescents. It is advised to consider the sleep duration and quality in the business plans for adolescents in order for the prevention of their body mass index.

시판 보냉팩 개수에 따른 진공포장 냉동 넙치(Paralichthys olivaceus) 및 고등어(Scomber japonicus) 필렛의 상온유통 중 선도유지능 비교평가

김소희,이지운,전은비,김진,박신영,이정석,So Hee Kim,Ji Un Lee,Eun Bi Jeon,Jin Kim,Pantu Kumar Roy,Shin Young Park,Jung-Suck Lee 한국수산과학회 2023 한국수산과학회지 Vol.56 No.6

The surge in online seafood consumption has increased parcel delivery, leading to a need to implement effective preservation methods. As the cold chain system is not fully established in Korea, styrofoam boxes and cold packs are commonly used for low-temperature seafood distribution. The impact of cold packs on product preservation depends on the number utilized. Herein, the freshness of vacuum-packed frozen fish fillets (Paralichthys olivaceus and Scomber japonicus) stored at 25±0.5℃ for up to 84 h was measured. Chemical (pH and volatile base nitrogen), microbiological (viable cell count), and physical (odor intensity) properties were assessed using 2 or 4 cold packs in a styrofoam box. Four cold packs yielded lower values, indicating superior freshness, and extended fish freshness by approximately 12 h compared with two cold packs. Therefore, it is recommended to use a minimum of 4 cold packs (-350 g/cold pack) in a styrofoam box for distributing approximately 300 g of frozen fish fillets at room temperature during the summer, considering an average delivery period of 2 days in Korea.

베트남 결혼이주여성의 문화적응 스트레스와 자녀양육효능감의 관계에서 배우자 지지의 영향

김소희,노윤구,Kim, So Hee,Noh, Yoon Goo 한국여성건강간호학회 2018 여성건강간호학회지 Vol.24 No.2

Purpose: To identify the effects of spousal support on the relationship between acculturative stress and sense of parenting competence among married Vietnamese immigrant women. Methods: The sample for this study consisted of 175 married Vietnamese immigrant women in Gyeongsangnam-do. Data were analyzed using descriptive statistics, t-test, ANOVA, $Scheff{\acute{e}}$ test, Pearson correlations, and hierarchical multiple regression with SPSS/WIN 23.0. Results: (a) sense of parenting competence was negatively correlated with acculturative stress, whereas a positive correlation was observed with spousal support; (b) spousal support mediated the relationship between acculturative stress and sense of parenting competence. Conclusion: Results of the study suggest that spousal support decreases the negative effects of acculturative stress on sense of parenting competence. Therefore, we need to find ways to strengthen spousal support for married Vietnamese immigrant women.

생달나무 잎 추출물 유래 항염 및 항산화 활성 성분

김소희,김정은,이남호,Kim, So Hee,Kim, Jung Eun,Lee, Nam Ho 대한화학회 2021 대한화학회지 Vol.65 No.1

In this study, the extract of Cinnamomum yabunikkei leaves were investigated for the anti-inflammatory and anti-oxidative activities and their active constituents were identified. In the anti-inflammatory tests using LPS-stimulated RAW 264.7 cells, the ethyl acetate (EtOAc) fraction inhibited the production of nitric oxide (NO) without causing cell toxicity. In addition, the EtOAc fraction reduced expression of iNOS protein and production of pro-inflammatory cytokines (TNF-α, IL-1β). Upon the anti-oxidative studies by DPPH and ABTS+ radicals, potent radical scavenging activities were observed in the EtOAc fraction. Five phytochemicals were isolated from the extract of C. yabunikkei leaves; (4S,5R)-4-hydroxy-5-isopropyl-2-methylcyclohex-2-enone (1), methoxy-(3,5-dimethoxy-4-hydroxyphenyl)ethanediol (2), afzelin (3), nicotiflorine (4) and narcissin (5). As far as we know, compounds 1-5 were isolated for the first time from this plant. In the anti-inflammatory tests for the isolates, compound 1, 3, 4 and 5 were determined to decrease NO production without causing cell toxicity. Furthermore, compound 1 reduced expression of iNOS protein and exhibited potent inhibitory activities of pro-inflammatory cytokines (TNF-α, IL-1β, IL-6). Based on these results, it was suggested that the extract and isolated compounds from C. yabunikkei leaves could be potentially applicable as natural source for pharmaceutical and/or cosmetic ingredients.

Respiratory Syncytial Virus 감염의 조기 진단 kit "바이오라인 알에스브이^TM"의 평가

김소희,성지연,양미애,은병욱,이진아,최은화,이환종,Kim, So-Hee,Sung, Ji-Yeon,Yang, Mi-Ae,Eun, Byung-Wook,Lee, Jin-A,Choi, Eun-Hwa,Lee, Hoan-Jong 대한소아감염학회 2007 Pediatric Infection and Vaccine Vol.14 No.1

Purpose : This study was performed to evaluate a new rapid diagnostic kit (BIOLINE $RSV^{TM}$; Standard Diagnostics Inc., Yongin, Korea), a lateral-flow immunoassay, in the detection of respiratory syncytial virus (RSV) from the nasopharyngeal aspirates (NPA) of children with lower respiratory tract infections (LRTIs) in comparison with other diagnostic methods. Methods : Three hundred and nineteen NPAs were selected from a large pool of NPAs that had been obtained from children with LRTIs. All specimens had already been tested for RSV by culture and immunofluorescent (IF) test, and had been kept frozen. Tests with BIOLINE $RSV^{TM}$ were performed at least twice. All who conducted the experiments or interpreted the test results were blinded to the results of both culture and IF tests. Results : One hundred seven (97.3%) of 110 specimens that were positive for RSV by both culture and IF test, 29 (87.9%) of 33 that were positive by IF test only, 20 (76.9%) of 26 that were positive by culture only, and 140 (93.3%) of 150 that were negative by both methods were negative for RSV by BIOLINE $RSV^{TM}$. By combining the above results, the following 5 diagnostic values of BIOLINE $RSV^{TM}$ were determined in comparison with viral culture or IF test; sensitivity, 92.3% (156/169, 95% confidence interval [CI], 87.1-97.5%); specificity, 93.3% (140/150, 95% CI, 88.4-98.2%); positive predictive value, 94.0% (156/166, 95% CI, 89.5-98.5%); negative predictive value, 91.5% (140/143, 95% CI, 86.0-97.0%); and agreement, 95.9% (306/319, 95% CI, 92.1-99.7%), respectively. Conclusion : This study revealed that BIOLINE $RSV^{TM}$ demonstrated good sensitivity and specificity for the detection of RSV antigen from NPAs of children with LRTIs. Because of simple methods and quick results, this test may be useful for the diagnosis of RSV infection during the epidemic periods.

간호대학생의 메타인지, 학습동기, 학업적 자기효능감이 자기주도학습능력에 미치는 영향

김소희(So Hee Kim), 이정민(Jung Min Lee), 김민경(Min Gyeong Kim), 김수아(Su Ah Kim), 김주은(Ju Eun Kim), 노윤서(Yun Seo Noh), 송지민(Ji Min Song), 이다원(Da Won Lee), 이소희(So Hee Lee) 다문화건강학회 2023 다문화건강학회지 Vol.13 No.1

Purpose: This study sought to identify the influence of metacognition, learning motivation, and academic self-efficacy on the self-directed learning ability of nursing students. Methods: A descriptive study design was used, and data were collected using self-reported questionnaires from 194 nursing students. Statistical analyses, including independent t-test, one-way ANOVA, Pearson's correlation, and multiple regression analysis, were performed using SPSS 26.0. Results: Metacognition, learning motivation, and academic self-efficacy significantly predicted nursing students' self-directed learning ability, accounting for 66.3% of the variance. Conclusion: Interventions to improve the self-directed learning ability of nursing students should focus on enhancing metacognition, learning motivation, and academic self-efficacy.

대학 온라인 강의에서 강의조직과 학습참여 및 지각된 학습성과 간 구조적 관계

김소희(So Hee Kim) 학습자중심교과교육학회 2022 학습자중심교과교육연구 Vol.22 No.21

목적 본 연구에서는 대학의 온라인 학습에서 강의조직과 학습자의 행동적, 정서적, 인지적 참여 및 지각된 학습성과 간 관계를 설정하고 이들 요인 간의 구조적 관계를 분석하고자 하였다. 방법 이를 위하여 서울 소재 K대학에서 2021-2학기 제공한 100% 온라인 강의 수강생 359명을 대상으로 관련 변인을 측정하기 위한 설문조사를 실시하였고 온라인 강의조직과 세 가지 유형의 학습참여 및 지각된 학습성과 간의 영향 관계를 구조방정식 모형을 이용하여 분석하였다. 결과 온라인 학습환경에서 지각된 학습성과에 유의한 영향을 미치는 요인은 강의조직, 행동적 참여 및 인지적 참여인 것으로 나타났다. 행동적, 정서적, 인지적 참여 간 관계를 검증한 결과 행동적 참여는 정서적, 인지적 참여에 정(+)적 영향을 미치고 정서적 참여는 인지적 참여에 정(+)적 영향을 미치며 정서적 참여는 행동적, 인지적 참여와 지각된 학습성과 간의 관계를 매개하는 것으로 나타났다. 결론 본 연구결과는 성공적인 온라인 학습을 위해 온라인 강의설계의 중요성을 확인하고 행동적, 정서적, 인지적 참여 간의 유기적인 관계를 이해함으로써 온라인 강의 설계 및 운영을 위한 교수전략에 시사점을 제공한다는 점에서 의의가 있다. Objectives This study aimed to analyze the structural relationships among online course organization, student engagement and perceived learning outcome in university online learning environment. Methods The survey data were collected from a total of 359 students who took the 100% online course offered by K University in the fall semester of 2021. The structural equation modeling was conducted to examine the relationships among course organization, behavioral, emotional, cognitive engagement and perceived learning outcome. Results The findings showed that online course organization had significant effects on behavioral engagement and perceived learning outcome. Behavioral engagement had a positive(+) effect on emotional and cognitive engagement, and emotional engagement had a positive(+) effect on cognitive engagement. In addition, emotional engagement was found to mediate the relationship between behavioral, cognitive engagement and perceived learning outcome. Conclusions This study attempts to broaden the understanding of student engagement reflecting multidimensional concepts by identifying the interrelationships among behavioral, emotional and cognitive engagement. Also, the results of this study can provide implications for teaching strategies to promote student engagement in online learning.

17세기 네덜란드 아동초상화에 재현된 놀이의 사회적 의미

김소희 ( So Hee Kim ) 미술사와 시각문화학회 2015 미술사와 시각문화 Vol.16 No.-

This study examines the societal and cultural meanings implicated in the children’s plays that the seventeenth-century Dutch paintings portrayed. The art historical researches have tended to regard the minors’ plays as pedagogical metaphors: for instance, top-spinning symbolizing parental discipline. It is true that the sixteenth-century Dutch society endorsed the playgames as a functional device for child education. But their popularity waned toward the end of the next century when juvenile plays as well as toys became associated with immaturity and considered unsuitable for the youths of a marriageable age. However, this study notes that the minors engaged in outdoor activities and playthings frequently appeared in the genre paintings, especially the children’s portraits at the time, begging questions about the objects’ renewed meanings. The present essay proposes that the plays and toys should be considered reflecting the common values and shared beliefs of Dutch society of the day. To prove the point, this essay analyzes a few pieces of child portrait which show children playing with rattles, colf clubs, and dolls. In these works the playthings not merely accentuate the vivacity of the children, but also regulate their social statuses, their legitimate gender roles, and their future occupations aspired by their parents. In the late seventeenth century Dutches were devoted to nation building, while the general principles underlying family life, public education, and gender roles called for re-conceptualization for realization of the collective goal. Therefore, this study concludes, it is such worldly views in transition that the children’s plays signify in the paintings.