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증례 : 혈액종양 ; 종양표지자의 상승을 동반한 국소 림프절 침범 신혈관근지방종 1예
홍유아 ( Yu Ah Hong ),김형욱 ( Hyung Wook Kim ),손덕승 ( Der Sheng Sun ),이해미 ( Hae Mi Lee ),유진영 ( Jin Young Yoo ),김훈교 ( Hoon Kyo Kim ),심병용 ( Byoung Yong Shim ) 대한내과학회 2011 대한내과학회지 Vol.80 No.2S
저자들은 종양 표지자 상승과 다발성 복강 내 림프절 비대로 전이성 악성 종양의 감별을 위하여 내원한 환자에서 조직 검사상 양측성 신혈관근지방종의 국소 림프절 침범과 무증상 결절성 경화증의 동반으로 확인된 증례를 경험하여 이를 보고하는 바이다. Angiomyolipoma is a rare, benign, mesenchymal hamartomatous neoplasm consisting of a mixture of adipose tissue, smooth muscle cells, and anomalous blood vessels. The kidney is a common origin site, but extrarenal angiomyolipoma has been reported. Simultaneous involvement of the kidney and regional lymph nodes is uncommon, and may be confused with a metastatic malignant lymph node. Lymph node involvement in angiomyolipoma represents a multifocal invasion of the tumor, rather than metastatic disease. Tumor markers usually associate with malignancy but they have sometimes been detected in benign conditions. We report a case of bilateral renal angiomyolipoma with tuberous sclerosis simultaneously involving regional lymph nodes confused with metastatic malignant lymph node enlargement due to associated elevation of serum tumor markers. (Korean J Med 2011;80:S287-S294)
상부 위장관 내시경으로 진단한 국소 전이된 갑상선 유두암 1예
강효승,박상현,김대진,원태식,조상진,이태웅 대한소화기내시경학회 2009 Clinical Endoscopy Vol.38 No.6
Papillary carcinoma is the most common malignant tumor of the thyroid gland, and it only infrequently invades the upper aerodigestive tract. When such invasion does occur, it is a source of significant morbidity as well as mortality. Although most thyroid tumors first clinically manifest as a neck mass, there have been few reports of patients whose initial compliant was a disturbance of the aerodigestive tract. The patient in our present study had no significant past medical history, and esophagoscopy and biopsy revealed papillary adenocarcinoma. We report here on a case of thyroid papillary carcinoma that was diagnosed by esophagoscopic biopsy. 갑상선 유두암은 국소 침범을 잘하지 않고 예후가 매우 좋은 암이지만, 기관이나 식도 등으로 국소 침범을 하게 되면 사망률은 급격히 증가하게 된다. 갑상선 암의 첫 증상은 대부분 목의 종괴로 나타나며, 드물게 호흡기나 소화기 증상을 나타내기도 한다. 갑상선 질환에 대한 과거력이 없는, 연하곤란을 주소로 내원한 환자에서 상부위장관 내시경 검사에서 식도 내강으로 돌출한 종괴가 있었으며, 그 조직 검사에서 갑상선 유두암을 진단하였다. 저자들은 상부 위장관 내시경 조직검사로 갑상선 유두암을 진단하였기에 문헌 고찰과 함께 보고하는 바이다.
종양표지자의 상승을 동반한 국소 림프절 침범 신혈관근지방종 1예
홍유아,김형욱,손덕승,이해미,유진영,김훈교,심병용 대한내과학회 2011 대한내과학회지 Vol.80 No.-
Angiomyolipoma is a rare, benign, mesenchymal hamartomatous neoplasm consisting of a mixture of adipose tissue, smooth muscle cells, and anomalous blood vessels. The kidney is a common origin site, but extrarenal angiomyolipoma has been reported. Simultaneous involvement of the kidney and regional lymph nodes is uncommon, and may be confused with a metastatic malignant lymph node. Lymph node involvement in angiomyolipoma represents a multifocal invasion of the tumor, rather than metastatic disease. Tumor markers usually associate with malignancy but they have sometimes been detected in benign conditions. We report a case of bilateral renal angiomyolipoma with tuberous sclerosis simultaneously involving regional lymph nodes confused with metastatic malignant lymph node enlargement due to associated elevation of serum tumor markers. (Korean J Med 2011;80:S287-S294) 저자들은 종양 표지자 상승과 다발성 복강 내 림프절 비대로 전이성 악성 종양의 감별을 위하여 내원한 환자에서 조직 검사상 양측성 신혈관근지방종의 국소 림프절 침범과 무증상 결절성 경화증의 동반으로 확인된 증례를 경험하여 이를 보고하는 바이다.
정상 성대 기능을 가진 갑상선유두암종 환자에서 암 침윤이 있는 반회후두신경 보존의 기능적, 종양학적 결과
김영록 ( Young Rok Kim ),김주연 ( Joo Yeun Kim ),김성원 ( Sung Won Kim ),이봉주 ( Bong Ju Lee ),차용우 ( Yong Woo Cha ),이강대 ( Kang Dae Lee ) 대한갑상선학회 2008 International Journal of Thyroidology Vol.1 No.2
Background and Objectives: Complete excision with resection of the recurrent laryngeal nerve (RLN) in differentiated papillary thyroid carcinoma (PTC) with invasion of RLN, reportedly did not improve the survival over incomplete excision. However some investigators have provided definitive oncologic and functional outcomes concerning the preservation of recurrent laryngeal nerve involved in thyroid cancer. Materials and Methods: The RLN involved by locally invasive papillary thyroid carcinoma was preserved in 15 patients with functioning vocal cord, between April 1998 and April 2004. Retrospective study was performed with medical records of 11 patients who were followed-up more than 48 months. All patients were treated by the shaving technique for RLN preservation. Postoperative radioiodine and thyroid stimulating hormone suppression therapy were combined for ablation of microscopic residual PTC. Results: Postoperative survival rate of the patients with RLN preservation was 100%, and local recurrence was not observed. There were 13 nerves showing infiltration by PTC during the operation. Permanent vocal cord paralysis was not observed and transient vocal cord paralysis occurred in 1 nerve (7.7%) of 1 patient. Conclusion: Although the number of patients and follow-up duration of the study may be limited, preservation of RLN infiltrated by PTC maintained the functioning vocal cord without any clinical recurrence.