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      • KCI등재

        위암발증 원인에 대한 생활습관 및 영양섭취에 있어서 농촌지역 주민 조사 : 강원도 화천군 주민의 Helicobacter pylori 감염률을 중심으로 Infection of Helicobacter pylori in Whachon Area, Kang-Won Do

        권태봉,이정선,우영국,이명헌,정철원,주진순 한국식품영양학회 1999 韓國食品營養學會誌 Vol.12 No.1

        위암발증의 원인을 밝히기 위하여 설문조사를 통하여 강원도 화천군에 거주하는 주민들의 일반사항, 생활습관 및 영양섭취실태와, ELISA법으로 Helicobacter pylori 감염률을 조사하였다. 조사 대상자는 40∼69세까지의 지역주민 169명으로 남자 79명, 여자 90명이었으며 그 결과는 다음과 같다. 조사 대상자의 학력은 65.7%가 초등학교 이하였으며, 월수입은 60%가 50만원 이하였다. 대상자의 62.7%가 농업에 종사하였고 자녀수는 64.3%가 3∼5명이었으며 대상자의 34.5%가 흡연을 하고 있었고 68.4%가 음주를 한다고 대답하였다. 대상자의 전체 평균신장은 156.7㎝로 여자는 150.1㎝, 남자는 164.4㎝ 이었다. 평균체중은 61.1㎏으로 여자의 체중은 57㎏, 남자는 65.7㎏이었으며 BMI는 전체 평균 25.5%로 여자는 24.8%, 남자는 20.1%이었다. Helicobacter pylori의 감염률은 전체 조사대상자의 66.3%이었으며, 여자의 67.7%, 남자의 64.6%가 감염되었고 연령별로는 40대의 70%, 50대의 62.2%, 60대의 69.4%가 각각 감염된 것으로 나타났다. 일상 생활 요인에 따른 Helicobacter pylori의 감염률은 흡연의 정도가 심하고 학력이 낮으며 월수입이 낮을수록 높은 경향을 보였다. Helicobacter pylori의 감염여부에 따라 감염자와 비감염자의 영양섭취량을 조사해 본 결과 비감염자는 감염자와 비교해서 에너지, 총단백질, 동물성 단백질, 칼슘, 비타민 C 섭취량이 높은 경향을 보였으며 철분과 niacin의 섭취량은 낮은 경향을 보였다. To examine the relationship between the casual infection of gastric cancer and lifestyle and nutritional status, we surveyed 169 persons, 90 females and 79 males, aged 40∼69 years from June 7 to June 14, 1997, in Whachon area, Kang-Won Do, Korea. For this purpose, we investigated Helicobacter pylori infection and identified the effect of sex, age, smoking, alcohol consumption, economic status, occupation, life-style and food intake on Helicobacter pylori infection. Helicobacter pylori status was evaluated using an enzyme-linked immunosorbant assay(ELISA) for anti-Helicobacter pylori immunoglobulin G(IgG). Helicobacter pylori infection was present in 66.3% of total subjects, namely, 67.7% of female and 64.6% of male and its prevalence increased with smoking, low education level and low monthly income. Energy, total protein, calcium and vitamin C intakes in the negative Helicobacter pylori infection group were higher than those in positive Helicobacter pylori infection group. However iron and niacin intakes were lower in the Helicobacter pylori negative group than in the positive group.

      • SCOPUSSCIEKCI등재
      • 單調增加荷重을 받는 平面 트러스의 複合 非線型 擧動에 關한 硏究

        權寧煥,金和中,金明璇,魯德煥 경북대학교 산업기술연구소 1990 産業技術硏究誌 Vol.18 No.-

        The object of this study is that develop computer program as being derive simple formula considering complex (material and geometric) nonlinear, and select the most useful truss in efficiency with the analysis Howe truss, Fink truss, Pratt truss and Warren truss. The complex nonlinear behavior is considered in this paper, so is acquired following results. 1. We developed program that could analyze complex nonlinear of plane truss. 2. In view of the results analyzied the numerical analysis example of plane truss, When Howe truss, Fink truss, Pratt truss, and Warren truss are equal to weight and span, and the same load is loaded. Among the trusses of same weight, Warren truss is the most useful in efficiency. And When height of warren truss is changed, the lower height of truss, the more useful in efficiency

      • 불소화계면활성제 함유 DPPC/Cholesterol 및 DPPG/Cholesterol 베지클의 BSA(bovine serum albumin)친화성 연구

        권경옥,김명자,김현영 숙명여자대학교 자연과학연구소 1998 자연과학논문집 Vol.- No.9

        본 연구에서는 항원(antigen). 항체(antibody) 등을 삽입시켜 자극반응성 베지클을 제조의 예비실험으로 대표적인 생체 단백질 BSA(bovine serum albumin)와 베지클의 친화도에 관해 알아보았다. DPPC(dipalmitoylphosphatidylcholine)/Chol, DPPG(dipalmitoylphos-Phatidylglycerol)/Chol,DPPC/Chol/FFS(ammonium pentadeca-fluorooctyrate)/FS(sodium bis(1H,1H,2H,2H-heptadecafluorodecyl)-2-sulfosuccinate), DPPG/Chol/ FFS/FS의 4종의 베지클을 제조하고, 제조된 4종의 베지클에 대해 column chromatography 법에 의해 BSA와의 흡착 여부를 확인했다. 실험 결과, 각 계의 베지클 입자크기는 BSA의 흡착으로 인해 감소하는 것으로 나타났고, 감소하는 정도는 DPPC/Chol와 DPPG/Chol에서 큰 것으로 나타났다. 반면, 제조된 계의 제타전위(ξ-Potential)값에는 거의 변화가 없었다. BSA와의 결합친화력의 비교에서는 DPPC/Chol. DPPG/Chol. DPPC/Chol/FFS/FS. DPPG/Chol/FFS/FS 순으로 낮아진다는 결과를 얻었다. 이들 실험결과에 바탕하여, 위의 4종의 베지클과 BSA와의 결합친화력에 대해 베지클의 표면전하와 베지클 막의 밀집성(compactness)이 영향을 미친다는 결론을 얻었다. The purpose of this study is to prepare a functional vesicle for the possible use as a biosensor. In this work, we have performed a preliminary experiment for biosensor, Four different systems of vesicle have been prepared with the composition of DPPC(dipalmitoylphosphatidylcholine)/Chol, DPPG (dipalmitoylphos-phatidylglycerol)/Chol, DPPC/Chol/FFS(ammonium pentadecafluoro-octyrate)/FS(sodium bis(1H,1H,2H,2H-heptadecafluorodecyl)-2-sulfosuccinate) and DPPG/Chol/FFS/FS. By use of column chromatography, it was found that BSA has been adsorbed onto the vesicle structure. The size of vesicle was found to decrease as adsorption occurs between the two species and the extent was greater in the systems of DPPC/Chol and DPPG/Chol. However, the δ-potential of the system remained essentially unchanged. The affinity of vesicle to BSA was found to decrease in the order of DPPC/Chol, DPPG/Chol, DPPC/Chol/FFS/FS and DPPG/Chol/FFS/FS. Based on these findings, it may be concluded that the affinity of vesicles onto BSA was affected by the surface charge and the compactness of vesicle.

      • KCI등재

        초·중·고 학생들의 과학 태도 변화에 대한 학습환경의 원인 분석

        권치순,허명,양일호,김영신 한국과학교육학회 2004 한국과학교육학회지 Vol.24 No.6

        최근 학교교육에서 학생들의 과학 태도에 대한 관심과 중요성이 증대되고 있다. 학생들의 과학 태도는 학업 성취도, 교육 프로그램의 일관성, 수업의 질뿐만 아니라 과학 교육의 관점과 과학 관련 직업 선택에도 영향을 준다. 그 동안의 과학 태도에 대한 선행 연구와 국제 비교 연구에 의하면, 우리나라 학생들의 과학 태도는 점차 하락하고 있는 것으로 나타났다. 이 연구에서는 초ㆍ중ㆍ고 학생들의 과학 태도 변화 과정을 알아보고, 이에 영향을 미치는 학습 환경 변인을 밝히는데 그 목적이 있다. 초등학교 3학년부터 고등학교 2학년 학생 약 6,925명을 대상으로 2003년 3월부터 3회에 걸쳐 학생들의 과학 태도와 학습 환경 검사를 실시하였다. 분석 결과, 학생들의 과학 태도는 일년 중 6월 이후에 낮아지고, 초등학교 4학년에서 중학교 2학년까지 과학 태도가 크게 변하였다. 과학 태도가 1학기보다는 2학기에 더 많이 하락하였으며, 초?중학교 학생들보다 고등학생들의 과학 태도 하락 폭이 더 컸다. 학생들의 과학 태도에 가장 큰 영향을 주는 요인은 과학에 대한 경험이고, 교사, 학급 분위기 등이 과학 태도 변화에 영향을 주는 것으로 나타났다. 학습 환경 변인은 과학 태도가 하락한 학생과 과학 태도가 상승한 학생이 각각 다르게 영향을 주는 것으로 밝혀졌다. 과학 태도에 영향을 주는 범주는 초등학교에서는 성, 학년, 지역, 중학교에서는 학년과 지역, 그리고 고등학교에서는 지역으로 나타났다. The importance of science attitudes is more increasing in science education. Science attitudes may influence students' attainment, consistency and quality of classwork as well as their later views of science education and scientific occupations. According to the international comparative researches and longitudinal studies on Korean students' science attitudes, it has shown that the more grade, the less science attitude. This research was survey the science attitudes and learning environment variables, and then make a inquiry that causes of decline of science attitudes. To study this purpose, the participating students in this study will be selected from 3th to 11th grade. 6,925 participants were administered 3 times in questionnaires of science attitudes and learning environment variables during a year. The result of this study showed that science attitude got low after June. Science attitude was changed from 4th grade to 8th grade students. Science attitude much more decrease second semester than first semester, high school students' science attitude fell much. It was experience about science that cause the biggest effect in science attitude and other learning environment variables influence in science attitude change. Learning environment variables made different influence from students of increased and declined science attitude. As category that influence in science attitude, in elementary school were gender, area and grade, in middle school were grade and area, and in high school was area.

      • 운동분류에 따른 체구성 성분 및 BMI의 비교

        최명화,권영우,김진해,민경선,민진아 한국스포츠리서치 2001 한국 스포츠 리서치 Vol.12 No.4

        The purpose of the present was to investigate the body composition and BMI in different sports groups with classification of sports. 121 male collegiate athletes were recruited from varsity team of golf(n=10), field hokey(n=18), tennis(n=8), judo(n=17), weight lifting(n=27), boxing(n=19) and bicycle(n=22). Sports event can be classified as low static/low dynamic such as golf(LSLD), low static/high dynamic such as hokey and tennis(LSHD), high static/low dynamic such as judo and weight lifting(HSLD), high static/high dynamic(HSHD) such as boxing and bicycle. With classification of sports events, percentage of body fat was significantly higher with HSLD group compared to HSHD group, but no measurable difference was LSLD and LSHD groups. LBM was significantly greater with HSLD group compared to LSHD and HSHD groups. Furthermore BMI of the HSLD group was higher than the other groups(p<.05). In conclusion, high static/low dynamic group were greater in %fat, LBM, BMI than other groups. The differences observed between different sports groups and classification of sports are related to metabolic and dynamic properties in different sports events.

      • 간편 퍼지와 디지털 PI+D를 이용한 제어 시스템의 설계

        박윤명,권태익,박종오,임영도,최부귀 동아대학교 정보기술연구소 2000 情報通信硏究所論文誌 Vol.8 No.1

        본 논문에서는 퍼지 디지털 PI+D제어기를 이용하여 외란, 잡음, 플랜트 변화 등에 강한 제어시스템을 설계한다. 퍼지제어는 간단한 4개의 규칙과 소속함수를 유도하여, 간편 퍼지를 이용한 디지털 PI+D 제어기를 설계하였으며 또한 플랜트는 2차 선형 플랜트를 적용하였다. 본 논문에서 제안한 제어 시스템과 디지털 PID 제어, 디지털 PI+D 제어 시스템을 시뮬레이션을 통해 각 시스템의 특성을 비교 하였다.

      • 한국인 심부전증 환자 심근에서의 인형 거대 세포 바이러스 감염

        이명용,이무용,김영권,한성식,최성준,김효수,이영우,서정돈 단국대학교 1998 論文集 Vol.33 No.-

        Objectives: In order to evaluated the prevalence and the site of infection of cytomegalovirus in terminally failing heart, cytomegaloviral DNA was detected in the explanted hearts of transplantation recipients. Methods: DNA extractions were performed from explanted failing hearts(N=22) and normal hearts(N=5) and polymerase cain reactions(PCRs) were done for detection of late gene sequence coding pp150 glycoprotein. The products were confirmed by electrophoresis on the 1% agarose gel. n order to improve the detectability of cytomegaloviral genome, nested PCRs were executed with the primers designed for the original 607 bp products. In situ PCRs also were done with the samples which were confirmed as positive for CMV viral genome by nested PCRs. Results: All patients had IgG anti-cytomegalovirus antibody and did not have IgM anti-cytomegalovirus antibody. Cytomegaloviral genomes in myocardium were detected by polymerase chain reaction. The 607bp products by PCRs were found in both explanted failing heart(3 cases/22. 13.5%) and normal hearts( 1 case/5, 20.0%). In nested PCRs, 186bp products were found in both failing hearts(LV 4/22, LA 3/2, RV 4/22, RA 0/17) and normal hearts(LV 2/5, LA 1/4, RV 2/5, RA 2/5). These was no significant change in positivity of cytomegaloviral DNA genome between failing and normal hearts. Total positivity of cytomegaloviral genome in explanted hearts was 44.4% according to the nested PCR results. The positivity of cytomegaloviral DNA by n situ PCR was 33.3%(4/12), and the site of positive reaction was the nuclei of the myocardial cells. Conclusion: Cytomegalovirus was rarely observed in explanted hearts of terminal heart failure and nested PCR could enhance the sensitivity of cytomegaloviral genome detection. The result of the in situ PCR showed the site of the cytomegaloviral infection was nuclei of the myocardial cells. Cytomegalovirus, however, might have no direct causal relationship in the development of terminal heart failure.

      • SCOPUSKCI등재

        무갑상선 쥐에서 중식성 반흔의 새로운 실험모델

        김영진,이백권,장도명,조길환,임풍 大韓成形外科學會 1999 Archives of Plastic Surgery Vol.26 No.4

        Proliferative scarring in the form of keloids and hypertrophic scars continues to be a clinical problem for some patients. The lack of an animal model for such scarring has been an obstacle to studying the biology and effective therapy of these entities. Consequently we created an accurate reproductive animal model to systematically study them. Human proliferative scars were explanted into flaps based on isolated vascular pedicles in congenitally rats. We compared the procollagen type Ⅲ peptide levels of proliferative scar tissue before and after explanting. The procollagen type Ⅲ peptide levels of explanted proliferative scar tissue remained increased as before explanting. Histological analysis of the explanted proliferative scar tissue revealed that all explants retained their original histotypic character even after 1 year. We could also retain the volume of implanted proliferative scar for 1 year and studied in vitro cellular proliferation. Fibroblast cultures from explanted scars demonstrated less aggressive growth characteristic than those from original surgical specimens. The advantages of this animal model are as follows: 1. The explants retain their histotypical character for a long period. 2. Placement of the explants outside the dorsum of a nude rat makes serial observation and measurement easier. 3. Agents under test can be injected into the explants through a catheter inserted into a single pedicle of island flap without the possibility of spreading systematically.

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