인후두이상감증 환자들에서 인후두역류의 확인에 있어 음성검사의 임상적 적용

허성철,홍석중,송용진,유승주,김상윤,남순열 대한이비인후과학회 2001 대한이비인후과학회지 두경부외과학 Vol.44 No.11

구강내 악성흑색종에 대한 임상연구

김욱규,허진호,황대석,김용덕,신상훈,김종렬,정인교 부산대학교 병원 암연구소 2008 부산대병원학술지 Vol.- No.23

The prognosis of oral malignant melanoma is poor compared with cutaneous melanoma. It may be related to the difficulty of wide enough resection, the early hematogenous matastases, higher stage at initial diagnosis, tendency to growth vertically. In the view of histological differences between oral mucosa and skin, it is impossible use Clark’s and Breslow’s classifications for prognosis. The great problem is that there is still no consensus on the treatment due to rarity. Because data collection from case reports is considered to be the best source of information and should be pooled to anlalyze key determinants of outcome, We reported on 6 cases of primary malignant melanoma of the oral cavity which were diagnosed and treated in Pusan National University Hospital recently and reviewed the literature. Immunohistochemical study on S100 Protein, GP 100 (HMB-45) with biopsy was usable to confirm the melanoma. Neck dissection including wide excision is recommended if lymph node involvement is suspected. Additionally, adjuvant chemotherapy could be supporting therapy.

소화관내 이물에 대한 고찰

윤한덕,류진호,박주경,허탁,조석주,김성근,민용일 大韓應急醫學會 1997 대한응급의학회지 Vol.8 No.1

We analyzed records at Chonnam university hospital from Sep. 1. 1993 to Aug. 31. 1996 to assess clinical significance of the foreign body in the gastrointestinal tract. There were 133 episodes consisting of 79 pediatric and 54 adult patients as possible to review. In the pediatric patients, the coin was the most common cause of foreign body ingestion, while adult patients were usually caused by bones and meat. We removed foreign bodies in the oral cavity and oropharynx in 12 cases using direct laryngopharyngoscpy and forcep. Endoscopy was performed successfully in 47 of 51 patients in which was attempted; there were two complications composed of an aspiration pneumonia and a mediastinitis due to esophageal perforation. There were spontaneous passage of foreign bodies in 48 cases. We observed complications in 6 cases in which 4 cases needed operations due to complications. Foreign bodies which pass into the stomach can be observed for development of complications, as 94% of foreign bodies which reach the stomach spontaneously pass. Only 4 patients required interventions, which was done without mortality.

하악골 골절 환자에 있어 수술후 합병증으로 발생한 골수염의 치험례

윤규호,전인성,신용길,박준호,허남오,방석준 大韓顎顔面成形再建外科學會 1996 Maxillofacial Plastic Reconstructive Surgery Vol.18 No.4

The term osteomyelitis literally means inflammation of bone marrow. It is described as an inflammatory condition of bone primarily engaging the medullary Following circulatory collapse and ischemia, the involved portions of the bone become necrotic. Cellulitis and osteomyelitis are the most frequent complications of fractures of the mandible and maxilla, because there is an abscessed tooth in the line of fracture. Since most fractures are compound fractures, infection may develop because of contact with oral secretions or outside air. The treatment of chronic osteomyelitis is still under debate. Some authors rely on antibiotics alone, while others advocate combination with surgery. But when infection occurs, establish proper drainage and administer antibiotics. Author treated a case of infected mandibular fracture with mandibular osteotomy, sequestrectomy, iliac bone graft and hyperbaric oxygen therapy, who had suffered suppurative osteomyelitis and mandibular nonunion following the open reduction of the mandibular fracture.

Dual Exposure Fusion with Entropy-based Residual Filtering

( Yong Seok Heo ),( Soochahn Lee ),( Ho Yub Jung ) 한국인터넷정보학회 2017 KSII Transactions on Internet and Information Syst Vol.11 No.5

This paper presents a dual exposure fusion method for image enhancement. Images taken with a short exposure time usually contain a sharp structure, but they are dark and are prone to be contaminated by noise. In contrast, long-exposure images are bright and noise-free, but usually suffer from blurring artifacts. Thus, we fuse the dual exposures to generate an enhanced image that is well-exposed, noise-free, and blur-free. To this end, we present a new scale-space patch-match method to find correspondences between the short and long exposures so that proper color components can be combined within a proposed dual non-local (DNL) means framework. We also present a residual filtering method that eliminates the structure component in the estimated noise image in order to obtain a sharper and further enhanced image. To this end, the entropy is utilized to determine the proper size of the filtering window. Experimental results show that our method generates ghost-free, noise-free, and blur-free enhanced images from the short and long exposure pairs for various dynamic scenes.

Structural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125

Heo, Yong-Seok,Kim, Su-Kyoung,Seo, Chang Il,Kim, Young Kwan,Sung, Byung-Je,Lee, Hye Shin,Lee, Jae Il,Park, Sam-Yong,Kim, Jin Hwan,Hwang, Kwang Yeon,Hyun, Young-Lan,Jeon, Young Ho,Ro, Seonggu,Cho, Joon Wiley (John WileySons) 2004 The EMBO journal Vol.23 No.11

<P>The c-jun N-terminal kinase (JNK) signaling pathway is regulated by JNK-interacting protein-1 (JIP1), which is a scaffolding protein assembling the components of the JNK cascade. Overexpression of JIP1 deactivates the JNK pathway selectively by cytoplasmic retention of JNK and thereby inhibits gene expression mediated by JNK, which occurs in the nucleus. Here, we report the crystal structure of human JNK1 complexed with pepJIP1, the peptide fragment of JIP1, revealing its selectivity for JNK1 over other MAPKs and the allosteric inhibition mechanism. The van der Waals contacts by the three residues (Pro157, Leu160, and Leu162) of pepJIP1 and the hydrogen bonding between Glu329 of JNK1 and Arg156 of pepJIP1 are critical for the selective binding. Binding of the peptide also induces a hinge motion between the N- and C-terminal domains of JNK1 and distorts the ATP-binding cleft, reducing the affinity of the kinase for ATP. In addition, we also determined the ternary complex structure of pepJIP1-bound JNK1 complexed with SP600125, an ATP-competitive inhibitor of JNK, providing the basis for the JNK specificity of the compound.</P>

Robust Stereo Matching Using Adaptive Normalized Cross-Correlation

Yong Seok Heo,Kyong Mu Lee,Sang Uk Lee IEEE 2011 IEEE transactions on pattern analysis and machine Vol.33 No.4

<P>A majority of the existing stereo matching algorithms assume that the corresponding color values are similar to each other. However, it is not so in practice as image color values are often affected by various radiometric factors such as illumination direction, illuminant color, and imaging device changes. For this reason, the raw color recorded by a camera should not be relied on completely, and the assumption of color consistency does not hold good between stereo images in real scenes. Therefore, the performance of most conventional stereo matching algorithms can be severely degraded under the radiometric variations. In this paper, we present a new stereo matching measure that is insensitive to radiometric variations between left and right images. Unlike most stereo matching measures, we use the color formation model explicitly in our framework and propose a new measure, called the Adaptive Normalized Cross-Correlation (ANCC), for a robust and accurate correspondence measure. The advantage of our method is that it is robust to lighting geometry, illuminant color, and camera parameter changes between left and right images, and does not suffer from the fattening effect unlike conventional Normalized Cross-Correlation (NCC). Experimental results show that our method outperforms other state-of-the-art stereo methods under severely different radiometric conditions between stereo images.</P>

Illumination and Camera Invariante Stereo Matching

Yong Seok Heo(허용석),Kyoung Mu Lee(이경무),Sang Uk Lee(이상욱) 한국통신학회 2009 한국통신학회 워크샵 Vol.2009 No.6

정적연소기 부실내 잔류공기 소기특성에 대한 수치해석적 연구

허형석(Hyeung Seok Heo),서용권(Yong Kweon Suh) 대한기계학회 2004 대한기계학회 춘추학술대회 Vol.2004 No.4

In this paper, we present scavenge characteristics in a small subchamber of HCCI. It is very important to enhance scavenge rate because ignition in a chamber sometimes does not happen. To understand this phenomenon numerical tool was performed using the FLUENT which is a commercial code. Focus is given to the effect on the scavenge rate of the geometric factor that is the angle of nozzle injection. The numerical results show that the scavenge ones in the subchamber heavily depend on the nozzle angle. It was found that the scavenge rate is more effective at angled nozzle.

Association between Workplace Risk Factor Exposure and Sleep Disturbance

Yong-Seok Heo,Sei-Jin Chang,Shin-Goo Park,Jong-Han Leem,Sung-Hwan Jeon,Bum-Joon Lee,Kyung-Yong Rhee,Hwan-Cheol Kim 대한직업환경의학회 2013 대한직업환경의학회지 Vol.25 No.-

Objectives: Sleep is essential for human beings to live and work properly. This study was conducted to investigate the relationship between occupational exposures to workplace risk factors and sleep disturbance in Korean workers. Methods: The data were drawn from the second Korean Working Conditions Survey (KWCS); a total of 7,112 paid workers were analyzed. The independent variables were occupational exposures such as physical, chemical, biological, and psychosocial risk factor in the workplace, and psychosocial risk factor was divided into five categories (job demand, job control, social support, job insecurity, lack of reward). We estimated the relationship between various occupational exposures and sleep disturbance using multivariate logistic regression analysis. Results: The results showed that people who exposed to physical, chemical, biological, and psychosocial (high job demand, inadequate social support, lack of reward) risk factors were more likely to increase the risk of sleep disturbance. Furthermore, after adjusting for general and occupational characteristics, we found significant positive associations between exposures to physical (odds ratios [OR] 1.47, 95% confidence interval [CI] 1.05-2.07) and psychosocial (high job demand (OR 2.93, 95% CI 2.16-3.98), inadequate social support (OR 1.57, 95% CI 1.14-2.15), lack of reward (OR 1.45, 95% CI 1.08-1.96)) risk factors and sleep disturbance. Conclusion: These results suggest that occupational exposures to physical and psychosocial workplace risk factors are significantly related to sleep disturbance.