서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1996)

김재홍,황동규,전재홍,김윤석,김중환,김용준,이창균,임동진,김현수,조창근,김경문,박상훈,전우형,김희성,이호정,차명수,김갑형,김형석,김석우,황지환,박병순,권오상,이민수,송기훈,성소영,이인섭,부태성 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2

Background : In recent years, gonorrhea has been panedemic and remains one of the most commom STDs in the world, especially in developing countries. Objective & Methods: For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results: In 1996, 139 strains of N. gonorrhoeae were isolated, among which 53(39.0%) were PPNG. Conclusion: Our results suggests that after a peak of 74.3% in 1993, the prevalence of PPNG in Seoul is gradually declining.

Poster Session : PS 0831 ; Upper GI Tract : Clinical Factors to Predict Angiographically Detectable Non-Variceal Upper Gastrointestinal Bleeding in Patients Refractory to Endoscopic Treatment

( Tae Hwan Ha ),( Tae Hoon Oh ),( Sung In Yu ),( Min Kim ),( Jong Wook Kim ),( Won Ki Bae ),( Jae Hyung Kim ),( Seung Suk Baek ),( Mi Jin Ryu ),( Ye Na Choi ),( Ji Young Park ),( Eileen L Yoon ),( Tae 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

Background: Non-variceal upper GI bleeding (NVUGIB) is a common medical problem that has signifi cant association with morbidity and mortality. Angiographic detection and subsequent transarterial embolization (TAE) is a primary treatment option when medical and endoscopic treatments fail. We investigated clinical factors that could affect the success of the angiographic detection and prognosis after TAE in patients with NVUGIB refractory to endoscopic therapy. Methods: A retrospective analysis of the clinical data was done in patients with failed endoscopic treatment who underwent angiography for the treatment of acute NVUGIB between May 2002 and May 2013. Patients were divided into detection or non-detection groups according to the presence of bleeding stigmata in angiographic fi nding. Rebleeding defi ned as subsequent bleeding event within 7 days and mortality within 30days were analyzed as outcome parameters after TAE following detection in angiography. Results: A total 45 patients 37 (male, mean age, 65.9±14.9 years) were analyzed and classifi ed as a detection group (n=25, 55.5%) and non-detection group (n=20, 44.6%). Peptic ulcers were the most common cause of refractory NVUGIB. Larger transfusion amount (5.7±3.9 unit vs. 3.5±2.8 unit; P=0.03), prolonged aPTT level (34.2±17.3 sec vs. 21.8±13.8 sec; P=0.01) and short time interval between last endoscopy and angiography (17.5±25.9 hours vs. 34.3±59.5 hours; P=0.04) were found to be signifi cant factors for predicting angiographic detection. TAE was performed in all patients detected in angiography. Rebleeding (44%) was significantly associated with higher Rockall score (8.3±1.5 vs. 6.6±2.4; P=0.046) and mortality (12%) was signifi cantly associated with higher Rockall score (9.3±0.6 vs. 7.1±2.2; P=0.002) and higher level of BUN (55.3±47.4 vs. 27.6±17.4; P=0.01). Conclusions: Clinical characteristics associated with angiographic detection in patients with NVUGIB refractory to endoscopic therapy were severe bleeding, bleeding tendency and early angiographic intervention. The Rockall score is useful parameter for predicting rebleeding and mortality after TAE.

베체트병 환자에서 Azathioprine으로 유발된 급성 췌장염 1례

김기향,권민정,김동기,김애란,김윤정,박지훈,이영태,박보민,김동욱 白中央醫療院 2005 仁濟醫學 Vol.26 No.1

Although many drug are thought capable of initiating acute pancreatitis, following azathioprine administration represents the 5% incidence by far the highest recorded incidence to date. We report a 35-year-old male who developed acute pancreatitis in the course of treatment with azathioprine for Behcet's disease. He was admitted due to abdominal pain, diarrhea, and fever for 10 days. Serum amylase and lipase levels were 510U/L and 3702U/L respectively. The abdominal CT scan revealed diffuse enlargement of the pancreas. There was no history of alcohol use or gall bladder disease. We considered drugs, especially azathioprine, as the cause of acute pancreatitis. We diagnosed it as acute pancreatitis. The patient was treated conservatively with hydration and analgesics. The symptom subsided within four days. Five days later, azathioprine was resumed. And the patient complained of abdominal pain. The elevated levels of serum amylase and lipase confirmed the recurrence of pancreatitis. His symptom subsided when azathioprine intake the stopped, and the serum amylase and lipase levels returned to normal level within five days.

글래스 아이오노머 이장재와 복합레진간의 결합강도에 관한 연구

김민희,정태성,김신 大韓小兒齒科學會 1999 大韓小兒齒科學會誌 Vol.26 No.3

본 연구는 현재 널리 쓰이고 있는 sandwich technique을 임상에 적용함에 있어서,GIC 이장재에 대한 이중중합형 레진과 비교적 근래에 소개된 compomer의 결합력을 측정하여 기존의 광중합형, 화학중합형 복합레진과 비교하고, 가장 우수한 결합력을 보이는 glass ionomer composite resin의 조합을 밝혀내고자 시도되었다. 이장용 재료로는, 광중합형인 GIC Vitrebond와 화학중합형인 GIC인 Ketac-fil을 사용하였으며,이 두가지의 이장재에 대해,광중합형 복합 레진인 Z-100,화학중합형 복합 레진인 Clearfil, compomer인 Dyract,그리고 이중중합형 복합 레진인 Bis-core를 축조하여 각 군당 10개씩, 총 80개의 시편을 제작하였다. 제작된 시편은 37℃의 증류수에 24시간동안 보관한 후,full load scale 50Kg,cross-head speed 1mm/min 조건의 만능 시험기에서 그 전단결합강도를 측정하였으며 실험결과는 student t-test로 검정하였다.본 연구의 결과는 다음과 같다. 1.Vitrebond를 이장재로 사용한 경우,Z-100이 가장 낮은 결합강도를 보였으며,나머지 세 재료는 결합력의 차이를 보이지 않았다(P<0.05). 2.Ketac-fil을 이장재로 사용한 경우,Clearfil이 가장 높은 결합강도를 보였고,Dyract, Bis-core가 중등도의 결합강도를,Z-100이 가장 낮은 결합강도를 보였다(P<0.05). 3.Clearfild은 Vitrebond 상방에서는 타 재료들과 비슷한 결합강도를 보였으나, Ketac-fil 상방에서는 가장 높은 결합강도를 보임으로써, GIC 이장재 종류에 따른 결합력의 차이를 보였으나 (P<0.05),나머지 세 재료의 경우에는 차이를 보이지 않았다(P>0.05). 4.Vitrebond를 사용할 때보다 Ketac-fil을 이장재로 사용할 때, 상부에 축조되는 복합레진의 종류에 따른 결합력의 차이가 더 크게 나타났다(P<0.05). For the purpose of providing suggestions in selection of filling materials used in `sandwich technique',the bone strengths between glass ionomer cement bases and composite resins were invetigated and compared. For lining materials,`Vitrebond' and '`Ketac-fil' were used.Using these two as bases,10 of each following resins were built up of the top ;Z-100(light curing resin),Clear-fil(chemical curing resin),Bis-core(dual cure resin),Dyract(compomer),therfore 10 specimens of each group and total of 80 specimens were made. After storing specimens in 37℃ deionized water for 24 hours,the shear bond strengths were measured under universal testing machine with 50 kg of full load scale and 1mm/min of crosshead speed and obtained the results as follows: 1.Over Vitrebond base,Z-100 showed the lowest bond strength but the other three did not show any difference in bond strength. 2.Over Ketac-fil base,Clear-fil showed the highest bond strength followed by Dyract,Bis-core,and Z-100 showed the lowest bond strengths. 3.Whereas Clear-fil showed the similar bond strengths on the Vitrebond base as other resins,it showed the highest bond strength on Ketac-fil base,which showed some difference in bond strength by differing GIC bases. 4.The bond strengths between base materials and composite resin showed a stronger resin-dependence tendency in cases with Ketac-fil bases rather than with Vitrebond bases.

感光基를 含有한 Polyester系 高分子 合成과 그 感光特性에 관한 硏究

金泰浩,金相敏,金相玟 成均館大學校 科學技術硏究所 1992 論文集 Vol.43 No.1

Studies on the polymers having two types of photosensitive functional groups were done. For a negative type photopolymer, polyesters such as isophthalic acid-adipic acid-glycerine (IAG), phthalic anhydride-trimethylol propane(PT), were prepared. And then cinnamoyl esters(IAGC and PTC) were obtained by esterificatin of IAG and PT with cinnamoyl chloride. This photosensitive properties of cinnamoyl ester(IAGC and PTC) were investigated by the change of solubility before and after exposure to light(254nm). For a positive type photopolymer three types of polyglyceryl phthalates having different degrees of polymerzation were prepared, and naphthoquinone -1, 2-diazide-5-sulfonyl chloride(NQDC) was added onto them by condensation. Photosensitive properties of NQDC on PG were investigated. On these experiments we obtained the following results ; for negative type photopolymer, photosensitive polymers incoporated with sensitizer showed more residual film than those polymer which have no sensitizer. As photosensitizer concentration is increased and optimum value of the risidual film yield was obtained by sensitizer concentration ratio 0.05. For positive type photopolymer, as degree of polymerization and added photosensitive group concentration is increased, the residual film yield is decreased.

COPA(cuffed oropharyngeal airway)를 이용한 마취 유도 시 근이완제 사용 유무에 따른 반응

김상태,배진호,김상범,임승운,민병상,신영덕 대한마취과학회 2000 Korean Journal of Anesthesiology Vol.38 No.3

Background : COPA (cuffed oropharyngeal airway) is a convenient device for airway management in patients undergoing general anesthesia for elective surgery in supine position. It causes less pharyngeal trauma than LMA(Laryngeal mask airway). The purpose of this study was to compare the effect of COPA with and without muscle relaxant. Methods : Forty patients with ASA physical status I and II for elective surgery were randomly assigned to two groups. Anaesthesia was induced with propofol (2 mg/kg) and vecuronium (1.5 mg/kg) and was administered intravenously in Group I but not in Group II. Mask ventilation was done for 5 min with 0: 5 L/min. COPA was placed and heart rate, and systolic, mean, diastolic blood pressure and peak inspiratory pressure were measured at 1 min interval for 5 min. Anaesthesia was maintained with pro- pofol 150 ㎍/kg/min, fentanyl 1 ㎍/kg/hr, O_2 2 L/min and N_2O 2 L/min. Results : There were no significant differences between Group I and Group II in heart rate, systolic, mean and dstolic blood pressure. PIP (Peak inspiratory pressure) was increased and hiccups occurred significantly (p $lt; 0.05) in Group II. Complete airway obstruction occurred in one patient of Group I and severe coughing, body movements and gagging occurred during induction and insertion in Group II. conclusions : With the use of appropriate muscle relaxant, we can use COPA without increased inspiratory pressure or significant complication. (Korean J Anesthesiol 2000; 38: 399~403)

유제놀에 의한 즉시형 알레르기 반응의 억제

김상현,신태용,김형룡,이영미,이은희,신보경,김윤철,안년형,김형민 우석대학교 의약품개발연구소 1996 藥學硏究誌 Vol.1 No.-

The current study evaluates the capacity of eugenol to regulate immediate allergic reaction by control of histamine release. Administrations of eugenol (1 M/kg. i.p.) at 60 min before and 5.10 min after the compound 48/80 treatment (8 mg/kg.i.p.) were shown the mortality rates as 0.44.4. and 77.8%. respectively. A 60 min before administered group revealed a singificant inhibition of serum his-tamine release compared with those of 5 and 10 min after the compound 48/80 injection. Eugenol (6-48mM) was also showed a dose-dependent activity on the compound 48/80-induced histamine release from the highly purified population of Alcian Blue-positive peritoneal mast cells. These results indicate that in vitro treatment with exogenous eugenol inhibited the active response of mast cell populations and modulated its characteristics.

경희대학교 평화의 전당 노래비 디자인

김동찬,김호겸,민창기,김태현,김용욱 경희대학교 디자인연구원 2003 예술· 디자인학연구 Vol.6 No.1

The purpose of this study is to design a basic draft of a monumental inscription with a poem of a peace for stirring up a peaceful mind. The inscription is expected to be a place for arousing a peaceful mind to visitors. Moreover, this place can be a place for culture and rest, which uplifts the image and phase of Kyunghee University to both.

코드 스멜 탐지를 위한 AST 메타모델의 확장과 OCL 명세

김태웅,김태공,김경민 인제대학교 2009 仁濟論叢 Vol.24 No.1

Recently, refactoring has been largely used to increase the efficiency of software development and decrease its maintenance costs. It is prior to determine the improvements before applying refactoring for improving the design of legacy code. Regarding this issue, Martin Fowler and Kent Beck proposed bad smells in code that identifies the design problem. Thus, this study detects the code smells automatically. To do this work, this study transforms the source code to an XMI document based on EAST meta model, which is an extended model of AST meta model. And the code smells that was defined with a natural language are specified using the OCL. Furthermore, this study performs the detection in which the code smell will be specified by using OCL and verifies its applicability and effectivity.

하악골 절제술후 재이식된 돌결자가골 재이식 : 치험 3례

김 식,김수관,김운규,김수민,류종희,이준길,조경안,김수흥,정태영,여환호 대한악안면성형재건외과학회 2001 Maxillofacial Plastic Reconstructive Surgery Vol.23 No.2

We described three cases of immediate reimplantation of a frozen-thawed autogenous mandible composed of a mixture of iliac bone, marrow, and particulate hydroxyapatite in tumors of the mandible. Acceptable outcomes were obtained in three patients who underwent immediate autogenous mandibular graft reconstruction. The conditions leading to successful outcome of the procedure are also discussed. Reimplantation of frozen autogenous lesioned mandible was performed in three patients with mandibular tumors. Two reimplanted grafts survived without complications following surgery. One case had postoperative infection that resolved with appropriate antibiotic treatment. There were no recurrences of the primary lesions. Satisfactory facial contour after surgery was achieved. These results are most promising, and we believe that, with further refinement, this technique will offer a new and acceptable modality for facial reconstruction in patients with cancer.