Preparation and characterization of ACs/TiO2 composite electrodes for improving the specific capacitance of electrochemical double-layer capacitors.

Seo, Min-Kang,Park, Soo-Jin American Scientific Publishers 2009 Journal of Nanoscience and Nanotechnology Vol.9 No.12

<P>In this work, the energy storage composite electrodes were prepared by mixing activated carbons (ACs) modified with a nanosize titanium oxide (TiO2) through a means of ultrasonic vibration in ethanol solution for 30 min. We examined the cyclic voltammetry of the composite electrodes in an aqueous electrolyte, 1 M H2SO4. It was found that the specific capacitance of the composite electrodes measured in a range of 0-0.8 V was increased from 100 to 155 F/g compared to carbon electrodes comprised of activated carbon only. This was attributed to a reduction of polarization of the ACs modified by nanosized TiO2.</P>

Effects of Atipamezole and Naloxone on Electroencephalographic Spectral Edge Frequency 95 in Dogs Sedated by Acupuncture at GV20 and Yintang Point

KIM, Min-Su,SEO, Kang-Moon Japanese Society of Veterinary Science 2007 The Journal of veterinary medical science Vol.69 No.5

<P>The purpose of this study was to evaluate the antagonism of acupuncture-induced sedation by electroencephalographic spectral edge frequency (SEF) 95 in 10 healthy intact male Miniature Schnauzer dogs (4.2-6.1kg; 2-3 years old) without neurological disorder. The GV20 and Yintang acupoints were administered for 20 min. While the dogs were conscious, SEF 95 baseline values were recorded at 2-min intervals for 4 min. Then acupuncture was administered at the GV20 and Yintang acupoints. During the acupuncture procedure, the SEF 95 values were recorded at 2-min intervals for 10 min. Subsequently, antagonist drugs, naloxone and atipamezole, were administered through the cephalic vein. The SEF 95 values were then measured again at 2-min intervals for 10 min. Those values were found to be significantly increased after administration of atipamezole in dogs sedated by acupuncture at the GV20 and Yintang acupoints (<I>p</I><0.05). However, the SEF 95 values in the naloxone groups did not show any significant changes before and after administration of the antagonist. It was concluded that sedation induced by acupuncture at the GV20 and Yintang acupoints might be partially associated with the α<SUB>2</SUB>-adrenergic system.</P>

Comparative evaluation of the algorithms for parametric mapping of the novel myocardial PET imaging agent ¹⁸ F-FPTP

Kim, Ji Who,Seo, Seongho,Kim, Hyeon Sik,Kim, Dong-Yeon,Lee, Ho-Young,Kang, Keon Wook,Lee, Dong Soo,Bom, Hee-Seung,Min, Jung-Joon,Lee, Jae Sung Springer Japan 2017 Annals of nuclear medicine Vol.31 No.6

<P><B>Objective</B></P><P>(<SUP>18</SUP>F-fluoropentyl)triphenylphosphonium salt (<SUP>18</SUP>F-FPTP) is a new promising myocardial PET imaging tracer. It shows high accumulation in cardiomyocytes and rapid clearance from liver. We performed compartmental analysis of <SUP>18</SUP>F-FPTP PET images in rat and evaluated two linear analyses: linear least-squares (LLS) and a basis function method (BFM) for generating parametric images. The minimum dynamic scan duration for kinetic analysis was also investigated and computer simulation undertaken.</P><P><B>Methods</B></P><P><SUP>18</SUP>F-FPTP dynamic PET (18 min) and CT images were acquired from rats with myocardial infarction (MI) (<I>n</I> = 12). Regions of interest (ROIs) were on the left ventricle, normal myocardium, and MI region. Two-compartment (<I>K</I><SUB>1</SUB> and <I>k</I><SUB>2</SUB>; 2C2P) and three-compartment (<I>K</I><SUB>1</SUB>–<I>k</I><SUB>3</SUB>; 3C3P) models with irreversible uptake were compared for goodness-of-fit. Partial volume and spillover correction terms (<I>V</I><SUB><I>a</I></SUB> and <I>α</I> = 1 − <I>V</I><SUB><I>a</I></SUB>) were also incorporated. LLS and BFM were applied to ROI- and voxel-based kinetic parameter estimations. Results were compared with the standard ROI-based nonlinear least-squares (NLS) results of the corresponding compartment model. A simulation explored statistical properties of the estimation methods.</P><P><B>Results</B></P><P>The 2C2P model was most suitable for describing <SUP>18</SUP>F-FPTP kinetics. Average <I>K</I><SUB>1</SUB>, <I>k</I><SUB>2</SUB>, and <I>V</I><SUB><I>a</I></SUB> values were, respectively, 6.8 (ml/min/g), 1.1 (min<SUP>−1</SUP>), and 0.44 in normal myocardium and 1.4 (ml/min/g), 1.1 (min<SUP>−1</SUP>), and 0.32, in MI tissue. Ten minutes of data was sufficient for the estimation. LLS and BFM estimations correlated well with NLS values for the ROI level (<I>K</I><SUB>1</SUB>: <I>y</I> = 1.06<I>x</I> + 0.13, <I>r</I><SUP><I>2</I></SUP> = 0.96 and <I>y</I> = 1.13<I>x</I> + 0.08, <I>r</I><SUP><I>2</I></SUP> = 0.97) and voxel level (<I>K</I><SUB>1</SUB>: <I>y</I> = 1.22<I>x</I> − 0.30, <I>r</I><SUP><I>2</I></SUP> = 0.90 and <I>y</I> = 1.26<I>x</I> + 0.00, <I>r</I><SUP><I>2</I></SUP> = 0.92). Regional distribution of kinetic parametric images (<I>αK</I><SUB>1</SUB>, <I>K</I><SUB>1</SUB>, <I>k</I><SUB>2</SUB>, <I>V</I><SUB>a</SUB>) was physiologically relevant. LLS and BFM showed more robust characteristics than NLS in the simulation.</P><P><B>Conclusions</B></P><P>Fast kinetics and highly specific uptake of <SUP>18</SUP>F-FPTP by myocardium enabled quantitative analysis with the 2C2P model using only the initial 10 min of data. LLS and BFM were feasible for estimating voxel-wise parameters. These two methods will be useful for quantitative evaluation of <SUP>18</SUP>F-FPTP distribution in myocardium and in further studies with different conditions, disease models, and species.</P><P><B>Electronic supplementary material</B></P><P>The online version of this article (doi:10.1007/s12149-017-1171-6) contains supplementary material, which is available to authorized users.</P>

K-POP 커버댄스 운동이 청소년 폭력 관련 심리 변인 및 혈중 호르몬 농도에 미치는 영향

서태범(Tae-Beom Seo),김영숙(Young-Sook Kim),김유미(Yu-mi Kim),강민정(Min-Jeong Kang),서경호(Kyeong-Ho Seo),박해찬(Hae-Chan Park) 한국생활환경학회 2015 한국생활환경학회지 Vol.22 No.5

The purpose of this study was to examine the effect of K-POP cover dance on violence related psychological factors, blood hormones, and neurotransmitters in adolescents. Participants in this study were 30 males and females taken blood sample and surveyed. All participants were performed K-POP cover dance (50~75%MHR, 80 min/day, 3days/week) during 8 weeks. School stress, assumed stress, interpersonal stress, ego stress were composed the stress factors. Body and verbal aggression, propriety, anger were composed aggression factors. School stress, assumed stress, interpersonal stress, ego stress were decreased significantly on K-POP cover dance. Also, body and verbal aggression, propriety, doubt, anger were decreased significantly on K-POP cover dance. Cortisol, melatonin, beta-endorphin, serotonin, dopamin were composed violence related blood factors. Cortisol were decreased significantly, but melatonin and dopamin were no significantly on K-POP cover dance. It is concluded that K-POP cover dance caused positive effects on violence and stress, stress related blood hormones.

건설공사 업무프로세스재설계(BPR) 기법 연구

강인석,곽중민,박서영,이동희,김창학 경상대학교 생산기술연구소 2001 工學硏究院論文集 Vol.1 No.-

The current trend of If (Information Technology) in 21st century demands management innovation, that is Business Process Reengineering (BPR) in all the industry including construction project. The solution of its demand is proposed by IT based on Internet. And also, in order to meet this objective, from 1997 domestic construction industry is accelerating to systematize CALS (Continuous Acquisition and Life-cycle Support) which is being planned to apply by government. These efforts give much weight to build computer systems rather than to improve and redesign construction business process that is more important for system application. This research develops a model for applying the BPR to construction industry, especially construction site that is a base to build a system for CALS. And the research suggests performing method, process and modeling technique of BPR to be applicable in business process redesign of construction field. Also, focusing on the research of execution step of business in construction site will be helpful for the site worker to perform BPR in construction site.

LC/MS/MS 분석법을 이용한 Amlodipine의 약물동태연구

서정원,윤민혁,강원구,권광일 충남대학교 약학대학 의약품개발연구소 2007 藥學論文集 Vol.22 No.-

The aim of this study were to confirm the analysis method and also to estimate the pharmacokinetic parameters of amlodipine in human volunteers. In an open-label single-dose pharmacokinetic study, a group, consisting of 24 healthy volunteers, received single oral dose of 5mg amlodipine. Blood sample were taken for up to 120 hours. The concentration of amlodipine in these body fluids was determinated using a validated high-performance liquid chromatography(HPLC) method with tandem mass spectrometry. Amlodipine and ketoconazole, an internal standard, were extracted from plasma using ethyl acetate in the presence of 0.1M sodium carbonate. After drying the organic layer, the residue was reconstituted in mobile phase(acetonitrile : water = 70 : 30 v/v (0.1% formic acid)) and injected onto a Zorvax C18 column (2.1 × 100 mm, 3.5 ㎛ particles). The isocratic mobile phase was eluted at 0.2ml/min. The ion transitions monitored in multiple reaction-monitoring mode were m/z 410.10 → 294.95 and 532.11 → 81.95, respectively. The coefficient of variance of the assay precision was less than 12%, and the accuracy exceeded 99.1%. The limit of quantification was 0.1 ng/ml. The pharmacokinetic parameters were calculated with non-compartmental(AUC, C_(max), T_(max), CL_(t), V/F) and compartmental(K_(el), K_(a), t_(lag)) pharmacokinetic analysis using WinNonlin program. The estimated means of AUC_(0-120hr), C_(max) and T_(max) were 196.90 ± 5.02 ng·hr/ml, 3.36 ± 0.09 ng/ml and 10.44 ± 0.61 hr, respectively. The means of other pharmacokinetic parameters(V/F, CL_(t), K_(el), K_(a) and t_(lag)) were 1208.06 ± 50.61 L, 25.39 ± 0.65 L/hr, 0.2806 ± 0.0294 hr^(-1), 0.0210 ± 0.0008 hr-1 and 0.4574 ± 0.0635 hours, respectively.

건설공사비 예정가격산정 및 적산기법의 개선방안 연구

강인석,박서영,이우식,곽중민 慶尙大學校 1998 論文集 Vol.37 No.-

Construction cost estimating is a procedure for surveying the price to complete a project. The results from cost estimating are used as scheduled budgets by public organizations and actual costs by contractors. This study analyzes the existing construction cost estimating system by the comparative study of cost items in Korea and Japan, and then suggests some methods with improvement related to the problems awaiting solutions. The proposed methods include the reorganized cost items for estimating construction cost and the improved procedures for estimating construction cost and the improved procedures for estimating construction equipment cost.

도로공사 우수배제시설의 시공성 및 성능 개선에 관한 연구

강인석,박서영,곽중민,이우식,정수언 경상대학교 생산기술연구소 2001 工學硏究院論文集 Vol.1 No.-

Generally, a street-inlet in road facility is aimed to exclude rainfall and filth from sewer system. In order to solve some problems in current street inlet facilities, some revised inlet systems have been suggested. Those revised facilities can also solve an environmental problem like a bad smell emitting from the worn facility and solve civil petitions due to its safety and poor quality of passing rainfall. In this study, the existing rainfall exclusion facility was investigated including foreign countries and a developed street inlet model was represented through estimating of their structures, characteristics and costs. It also be analyzed that the existing problems can be solved by a trial construction and the developed model was compared with existing models by focusing on constructability and maintenance capacity.

웹기반 통합데이터베이스에 의한 건설정보관리 방안

서정헌,박서영,곽중민,강인석 경상대학교 생산기술연구소 2002 工學硏究院論文集 Vol.2 No.-

Recently, our construction industry is using various work sections classification systems for civil engineering projects. However, because the public IDB(Integrated DataBase) for the work sections is insufficiently built, it is difficult to connect construction operation information from construction site to standard specification or standard method of measurment. Therefore, this study suggests a methodology to link the construction work sections information, such as cost, schedule, drawings and specification, with civil engineering standard method of measurement. And the methodology suggested in this study was applied to a web-based work sections information management system with IDB. An IDB modeling was designed by using DFD (Data Flow Diagram) and ERD (Entity Relationship Diagram).

백서 척수후근절로부터 슈반세포의 효과적인 체외 배양법

김성민,이종호,김남열,안강민,최원재,최시호,차미주,이주영,황순정,장정원,명훈,최진영,서병무,정필훈,김명진 大韓顎顔面成形再建外科學會 2003 Maxillofacial Plastic Reconstructive Surgery Vol.25 No.4

Schwann cells(SCs), an important component of the peripheral nervous system, intract with nerous to mutually support growth and replication for the peripheral nerve regentation. Recently, ading SCs to the lumen of guidance channel is widely tried to improve regeneration or to make regeneration possible over otherwise irreparable gaps. however, it is not easy to isolate and multiplicate SCs as much as enough to help the axonal regeneration. For the allogeneic SCs source for tubular nerve guidance, we developed a little bit improved technique of harvesting and multiplicating SCs. by culturing dispersed dorsal root ganglia in specially designed medium with growth factors and serial processing, we repeatedlly generate relatively homogenous SC cultures. Our technique was compared with other methods of literature using immunostaining methods such as GFAP, S100, BDNF and the total SC count assessment at different time interval after primary culture.