두가지 혈류 유발방법에 의한 새로운 심폐소생술(이중 혈류 유발 심폐소생술)장치의 개발

황성오,김현,조준휘,오범진,임종천,최경훈,윤정한,이승환,김영식,이강현,이윤선 大韓應急醫學會 1999 대한응급의학회지 Vol.10 No.2

Background: There have been many efforts to augment blood flow during cardiopulmonary resuscitation. These efforts have focused on maximizing the effect of cardiac pump or thoracic pump alone. However, considering that the heart is the biggest blood reservoir and increase of intrathoracic pressure can generate blood flow, simultaneous exploitation of both mechanisms may have synergistic effect. We hypothesized that simultaneous chest constriction in addition to sternal compression by standard CPR may have additive hemodynamic effects by preventing deformation of the chest and increase of intrathoracic pressure. Methods and results: we built a new mechanical device to perform compression and thoracic constriction simultaneously. The device consists of two main elements. Piston in the center is to depress the sternum. Strap is to constrict the thorax circumferentially. Strap is attached to both sides of the piston. When the piston is pushed down, it depresses the sternum and pulls on the thoracic strap. To determine strap width to produce optimal hemodynamic effect, we measured hemodynamic parameters with variable widths of strap in two dogs after induction of ventricular fibrillation. Result of the experiment showed that 10cm wide strap was determined to be most effective. We also determined optimal depth of compression to produce maximal hemodynamic effect with animal experiments using two dogs. Animal experiments showed that the highest aortic pressure could be generated when the stemum was depressed to 5 cm. Cardiopulmonary resusciation using a new device could generate higher systolic aortic pressure, coronary perfusion pressure and end-tidal carbon dioxide tension in comparison with standard cardiopulmonary resuscitation in a pilot animal study using two dogs. Conclusion: New cardiopulmonary resuscitation method using a mechanical device designed by us could perform sternal compression and simultaneous thoracic constriction, and generate better hemodynamic effects than standard cardiopulmonary resuscitation in pilot animal experiments.

혼수상태의 외상환자에서 초음파를 이용한 흉부 및 복부손상의 진단

임경수,이강현,이진웅,이부수,황성오,유수영,강성준 대한응급의학회 1995 대한응급의학회지 Vol.6 No.1

The need for rapid diagnosis and treatment of life-threatening thoracic and intra-abdominal injury result in controversy over the appropriate triage of unconscious blunt trauma patients. To aid in early decisions for these patients, a prospective analysis of 98 patients with glasgow coma scale(GCS) scores≤8 was undertaken. Although intra-thoracic and intra-abdominal injuries were frequently identified based on systolic blood ressure, the use of clinical signs alone resulted in more missed injuries than did using the emergency ultrasonography. In normotensive patients(n=34), intra-thoracic injuries was identified in one patient(2.9%), and intra-abdominal injuries were in 7 patients(20.6%). In shock(systolic blood pressure<90mmHg) Pa-tients(n=64), thoracic injuries and intra-abdominal injuries were diagnosed in 8(12.5%) and 27 patients(42.3%), thoracic and abdominal combined injuries were identified in 11 patients(17.2%). The sensitivity, specificity, and accuracy of emergency ultrasonography were 96.3%, 91.7%, 94.9%. This study suggests that all unconscious trauma patients undergo immediate emergency ultrasonography to prevent missing life-threatening injuries.

Purge & Trap-GC를 이용한 의약품 필름코팅 정제 중 잔류용제에 관한 연구

장준식,이명자,소유섭,문춘선,이주헌,박희라,김진숙,강경모,이선옥,방성연,유미자,유문균,금오성,이병욱 식품의약품안전청 2000 식품의약품안전청 연보 Vol.4 No.-

의약품은 약물을 생체에 적풋하기 위하여 유효성분의 효과가 언제나 일정하게 확보되고 사응에 편리하도록 만들어지는 것이므로 유효썽분 이외에 약효에 영향을 주지 않는 성분이 첨가되는 경운가 많다. 이 때 사용되는 용매들은 제피의 광택 및 건쪼시간의 단축 등을 위하여 휘발점이 낮을 용매들이 주로 사용되어진다. 본 연구는 의약품 필름코팅정제 중 잔류용매 4종(chlorofonr benzen, trichloro ethylen, 1,4-dioxane)에 대한 변형된 pirge & trap-GC 장치를 이용한 동시분석방법을 개발하였으며, 각 표준품의 RSD 값은 chloroform 3.03%, benzen 3.17%, trichloroethylen 3.69% and 1,4-dioxane 3.41%였다. 또한 시중 유통중인 의약품 50종에 대하여 잔류웅매 양을 측정하였으며, 검출되는 잔류용매는 한 건도 없었다. This study nras carried out to develope the analytical method for the mixture of chlorefonn, benzen, trichloroethylen and 1,4-dioxane simultaneously and determine the remainingorgauic solvents in coating tablets by Purge & Trap-GC. The results were as follouFs ; 1. Chloroform, benzen, trio:tloroethylen and 1,4-dioxane separated by tenax #5 trap by HP-624GC column by terrlperature programming. The peaks were separated completely at retentiontime of 6.88min for chloroform, 8.21min for benzen, 10.38miu for trichloroethylen and 11.95minfor 1,4-dioxane. 2. Standard RSD were individually chloroform 3.03%, benzen 3.17%, trichloroethylen 3.69%and 1,4-diorane 3.41%. 3. 60 samples were not detrcted chloroform, benzen, trichloroethylen and 1,4-dioxane.

Erratum to: Intracellular Substrates of a Heme-Containing Ascorbate Oxidase in Pleurotus ostreatus

Seung-Rock Lee,Woo-Jeong Joo,Yong-Un Baek,Youn-Kyong Lee,Seong-Woon Yu,Yeon-Ran Kim,Kee-Oh Chay,Seung-Hyun Cho,Sa-Ouk Kang 한국미생물학회 2009 The journal of microbiology Vol.47 No.6

In the online version of the article the name of the second corresponding author is misspelled. The correct spelling is Sa-Ouk Kang. The online version of the original article can be found under doi: 10.1007/s12275-008-0307-8

A Study of Efficient Connection using Mobility Property in Mobile Ad-hoc Network

Youngj-jun Oh1,Kang-whan Lee 보안공학연구지원센터 2014 International Journal of Multimedia and Ubiquitous Vol.9 No.12

In this paper, we proposed the context-awareness routing algorithm DDV (Dynamic Direction Vector)-hop algorithm at Mobile Ad-hoc Networks. Existing algorithm in MANET, it has a vulnerability that the dynamic network topology and the absence of network expandability of mobility of nodes. This proposed algorithm forms cluster formation using a range of direction and threshold of velocity by base-station, and we calculate exchange cluster head node probability using direction and velocity for maintaining cluster formation. DDV algorithm forms a cluster based on the cluster head node. As a result of simulation, our scheme could maintain the proper number of cluster and cluster members regardless of topology changes. In response to maintain cluster formation, we prove a continuous connection between nodes.

수부 주상골 요부의 전위골절에 대한 수술적 치료

조용만,이영기,강흥식,리건영,이천동,오상수 대한골절학회 1997 대한골절학회지 Vol.10 No.1

The authors surveyed the clinical study of 17cases of scaphoid fractures from March 1989 to September 1994 with minimal I year follow up at Department of Orthopedic Surgery, Lee-Rha general Hospital. The following conclusions were obtained through clinical survey. l. Of all l 7 cases, they were l3 males and 4 females; Among the 13 males, 10 cases were aged between 20 and 39 years. forming 56.8% of all. 2. All 17 cases were treated by open reduction. Unions were obtained at average l l.5 weeks in 7 cases treated with Herbert screw fixation and l 2 weeks in l 0 cases treated with K-wire fixation. 3. Two of ten K-wire treated cases resulted in delayed union, one of seven Herbert screw treated cases resulted in delayed union. 4. Unions were obtained at average 20 weeks in 3 cases of delayed union. We concluded that open reduction and K-wire fixation were recomanded for the compatible treatment method of displaced waist fracture of scaphoid.

Hepatic Cirrhosis Occurring in a Young Woodchuck(Marmota monax) Due to Vertical Transmission of Woodchuck Hepatitis Virus(WHV)

Kyu-shik Jeong,정원일,Jae-yong Chung,Mi-young An,Chae-yong Jung,Gyoung-jae Lee,Jong-soo Kang,Byeong-cheol Kang,Young-heun Jee,Bruce H Williams,Young-oh Kwon,Da-hee Jeong 대한수의학회 2003 Journal of Veterinary Science Vol.4 No.2

Cirrhosis Occurring in a Young Woodchuck (Marmota monax) Due to Vertical Transmission of Woodchuck Hepatitis Virus (WHV)Da-hee Jeong, Won-il Jeong, Jae-yong Chung, Mi-young An, Chae-yong Jung, Gyoung-jae Lee1, Jong-soo Kang1, Byeong-cheol Kang2, Young-heun Jee3, Bruce H Williams4, Young-oh Kwon5 and Kyu-shik Jeong*College of Veterinary Medicine, Kyungpook National University, Daegu 702-701, Korea1Shinwon Scientific Co., LTD, Research Institute, Suwon, Korea2Clinical Research Institute, Seoul National University, Seoul 110-744, Korea3College of Veterinary Medicine, Jeju National University, Jeju 690-756, Korea

대인불안과 사회문화적 요인의 상관관계

오강섭,허묘연,이시형 대한신경정신의학회 1999 신경정신의학 Vol.38 No.1

연구목적 : 한국 일반인들에 대한 사회공포 증상의 정도와 양상, 기능의 손상정도 등을 알아보고, 대인불안과 성격특성, 부모의 양육태도, 대인관계에서의 특징들간의 상관정도를 알아보기 위한 것이다. 방 법 : 서울지역에 거주하는 일반 중학생, 고등학생, 대학생 및 성인 1087명을 대상으로 전반적인 사회적 상황에서의 불안과 회피 정도, 증상과 상황, 대처방법, 가해의식, 일상생활에의 영향을 조사하였고, 내-외향성 검사, 부모양육태도 검사와 대인관계태도 검사를 이용하여 대인 불안과 관련된 성격과 사회적인 요인을 평가하였다. 결 과 : 대인불안 증상은 정시곤란, 실수공포, 표정공포, 횡시공포, 타인시선공포가 전 연령에 걸쳐 높게 나타났다. 청소년기는 전반적으로 대인상황에 대한 불안 수준이 올라가 있고, 중학생과 고등학생의 경우 남자가 여자에 비해 유의미하게 높은 정도의 대인불안을 갖고 있는 것으로 나타났다. 가해의식은 성인으로 갈수록 줄어드는 경향이 있었다. 대인불안의 상황은 모든 연령에서 연단이나 면접상황에서 가장 많은 어려움이 호소하였으며, 대처방식의 경우, 연령이 증가할수록 ‘그럴 수 있다’ 건강한 대처방식의 비율이 높아지는 것으로 나타났다. 내향성에 대한 자신의 평가와 타인의 평가를 비교해보면, 모든 연령집단에서 타인이 평가하는 것보다는 자신이 스스로를 더 내성적인 것으로 생각하였다. 양육태도의 경우에는 아버지나 어머니 모두, 거부나 높은 기대, 불안, 통제적인 태도는 대인불안이 높은 것과 관련되어 있는 반면에 감정적인 지지를 나타내는 태도는 낮은 대인불안과 관련되어 있었다. 대인관계태도에서 자기 바하나, 은근성, 타인의 의견을 지나치게 염려하는 태도, 체면 등은 대인불안과 유의미한 관련성을 나타냈으며, 사교성이나 응석은 대인불안과 부적인 관계를 갖는 것으로 나타났다. 결 론 : 대인불안의 정도, 내향성, 대인불안 및 회피 정도와 일상생활에서의 지장 정도간에 서로 깊은 상관관계를 나타내어, 대인불안의 정도와 내향성이 높을수록 일상생활에의 지장이 많은 것으로 판단되었다. 부모의 양육태도에서는 거부, 높은 기대, 불안, 통제적 태도 등이, 대인관계태도에서는 자기비하, 은근성, 타인의견 염려, 체면 등이 대인불안과 관련되는 것으로 나타났다. Objectives : We examined the degree of social anxiety and physical symptoms, situations, maneuvers in phobic situations, the degree of offending others, disability in normal Korean sample. And We also studied the correlations of social anxiety and socio-cultural factors (personality characteristics, child rearing attitudes and interpersonal attitudes). Methods : The subjects were total of 1087 including junior high school students, high school students, college students and adult population living in Seoul. We administered the following scales : SAD(Social Avoidance and Distress Scale), Social Anxiety Symptom and Situation, Maneuvers in Phobic situations, Offending others, SDS(Sheehan's Disability Scale), EPQ(Eysenck Personality Questionnaire), Child Rearing Scale and Interpersonal Attitude Scale. Results : Among social phobic symptoms, fear of eye to eye contact, fear of mistake, fear of facial expression, fear of side glancing and fear of other's gazing were prevalent in decreasing order. The level of general social anxiety were high in junior high school and high school students, and male subjects reported more social anxiety. the degree of offending others decreased with age. The most difficult social anxiety situations were public speaking and interviewing. The frequently used maneuver in phobic situations was reasoning. All subjects perceived themselves more introverted than others did. On the Child rearing attitude, rejection, high expectation, anxious, control subscales of both parent were correlated with high level of social anxiety, and the emotional care was correlated with low level of social anxiety. On the interpersonal attitudes, self-devaluation, indirectedness, overconcern of other's opinion, face saving subscales were positively correlated with social anxiety, and the socialization and eungseok were negatively correlated with social anxiety. Conclusion : The social anxiety and the introversion were associated with the disability of daily activity. Some subscales of child rearing attitudes and interpersonal attitudes were also associated with the social anxiety.

심폐소생술중 심실기능 및 판막운동의 평가

이부수,김영식,이강현,황성오,임경수,박금수,윤정한,안무업,최경훈 대한응급의학회 1994 대한응급의학회지 Vol.5 No.2

Background : Mechanism of blood flow during cardiopulmonary resuscitation(CPR) in humans remains controversial and poorly understood, although cardiac or thoracic pump theory was proposed. We investigated cardiac movement, ventricular function and atrioventricular valve motion with aid of transesophageal echocardiography during precordial compression during CPR in humans. Methods and results : During CPR transesophageal echocardiography was performed in 14 patients with non-traumatic cardiac arrest. Manual precordial compression during CPR was performed according to American Heart Association guidelines. Mitral valve closed in 9 and did not close in 5 patients during "compression systole". Tricuspid valve closed during compression systole. Compression vector directed to right ventricle, basal portion of interventricular septum and left atrium. The heart rotated clockwise and the apex was more displaced than the base("swing motion"). Fractional shortening(FS) and ejection fraction(EF) of right ventricle exceeded those of left ventricle(FS : 55±9% vs 18±8%, p<0.05), EF : 79±9% vs 37±16%, p<0.05). FS and EF of left ventricle was higher in patients with systolic mitral valve closure than patients with persistent systolic opening of mitral valve(FS : 21±7 vs 13±7%, EF : 45±12 vs 22±12%, p<0.05), but FS and EF of right ventricle was not different. Conclusion : During precordial compression, the heart rotated clockwise and displaced. Systolic function of right ventricle exceeded left ventricle. Marked compression of right ventricle and systolic closure of tricuspid valve suggested that right ventricle functioned as a pump generating blood flow during precordial compression. Closure of mitral valve was dependant on systolic function of the left ventricle.

간호대학생들의 대인가치관과 가치관변화에 대한 연구

이강오,장수현,나덕미 朝鮮大學校 附設 醫學硏究所 1989 The Medical Journal of Chosun University Vol.14 No.1

The purpose of this study is to determine interpersonal values and value change of the four year course nursing students. The survey was conducted against 217 students of a department of nursing, from all classes (freshman, sophomore, junior and senior). This study was conducted during the period of 7th through 15th of march 1987 in accordance with the Lee Kyung-Hye and Hawang Eung-Yun's "Survey of Interpersonal Values (STV)." The results of the study were as follows: 1. Those nursing students surveyed show that conformity (18.32) took the highest place and leadership (8.64) lowest in the general value orieUtaiton. In accordance with the Lee and Hwang's SIV, those of other woman college students indicate 32~63% tile, respectively. 2. Changes in values by class were significant difference. (P<.05) Accordingly, the hypothesis 1 of this study has been supported. 3. Significant variation has been shown by each class in each factor such as conformity and leadership but no variation has been indicated in benevolence, independence, support and recognition. 4. There was significant difference in values between higher class (junior and senior) students with clinical experience and starting class (freshman and sophomore) students without clinical experience. (P<.05) The study indicates the values of higher class students is lower than that of starting class students. Therefore, the hypothesis 2 of this study has been supported. 5. There was no significant difference in values between entering students and graduating students. (P>.05) Thus, the hypothesis 3 of this study has been rejected. The results of the study show that there is no positive influence curricuium and clinical practice in forming the value for the students. Thcrefore, it is concluded that new strategy of clinical practice and special education program should be established for fromation of the right values for the nursing students.