복부기형혈관의 문맥-체순환 단락으로 유발된 만성 후천성 간뇌 퇴행중 1례

김대현,김종국,차재관,김상호,김재우 대한신경과학회 1998 대한신경과학회지 Vol.16 No.2

농산물 소독과정에서 브롬화메틸에 노출된 근로자에게 발생한 신경병 2례

박태혁,김정일,손지언,김종국,김형수,정갑열,김준연 大韓産業醫學會 2000 대한직업환경의학회지 Vol.12 No.4

목적 : 농산물 소독과정에서 브롬화메틸에 노출된 근로자에게 발생한 신경병 2례 보고. 방법 : 피로감, 전신무력감, 어지럼증, 보행장애 등의 증상을 주소로 내원한 브롬화메틸을 사용하여 방역작업에 종사하는 건강한 20세와 18세의 근로자를 대상으로 혈액검사, 신경정도 및 근전도검사, 뇌자기공명영상 등의 임상검사와 작업력조사를 시행하였다. 결과 : 1례에서 뇌자기공명영상에서 연수와 소뇌의 양측 측충부의 고신호강도가 관찰되었고 11일 후의 추적조사에서 동일 부위의 고신호강토가 감소된 소견이 관찰되었으며 뇌병증으로 최종 진단되었다. 다른 1례는 신경전도검사에서 다발성 신경병 소견과 뇌유발전위검사에서 우측 하부 뇌간부위 병소가 관찰되었고 뇌병증 및 말초신경 병으로 최종 진단되었다. 결론 : 근로자들의 증상은 소독과정에서 브롬화메틸 노출로 인한 신경 병으로 판단되며 훈증소독과방역작업에 종사하는 근로자들의 실태조사와 안전에 대한 대책이 시급하다고 하겠다. Objectives : To report two cases of neuropathy due to methyl bromide intoxication. Methods : Workers, engaged in the fumigating process, complained fatigue, general weakness, ataxia, and hypersomnia. We evaluated them with blood tests, neurophysiologic studies and MRI and investigated their occupational history. Results : Increased signal intensities were found in the medulla oblongata and paraver mian of cerebellum in MRI and after 11 days, high signal intensities were reduced in the following MRI. In the other case, polyneuropathy and rlght lower brainstem lesion were observed In the NCV and BAEP studies. Conclusions : We confirmed that worker's symptoms were related to methyl bromide exposure in the fumigation. It is necessary that we should evaluate present condition of fumigating process and prepare appropriate methods to protect workers engaged in the fumigation.

위암 환자에게 세포성 면역 기능에 관한 연구

이재익,윤일국,이종선,김종완,장준,안정기,송민호,정현용,이헌영,김상용,김영건 忠南大學校 癌共同硏究所 1991 癌共同硏究所 硏究誌 Vol.1991 No.-

위암 환자에서 세포성 면역 기능에 관한 연구

이재익,윤일국,이종선,김종완,장준,안정기,송민호,정현용,이헌영,김삼용,김영건 충남대학교 암연구소 1991 癌共同硏究所 硏究誌 Vol.1 No.1

We performed a variety of lymphocyte stimulation tests, delayed hypersensitivity skin tests, and enumeration of several lymphocyte subpopulations in 21 patients with gastric cancer who did not receive any form of anticancer therapy, and in 20 healthy controls. The gastric cancer patients had significantly decreased number and total score of positive reactions in delayed hypersensitivity skin tests compared with the healthy controls. The percent of CD_(4) positive lymphocytes in the gastric cancer patients was significantly decreased compared to the normal control subjects, but it had no correlation with the total score of delayed cutaneous hypersensitivity reactions. The ratio of helper to suppressor cells was lower in the cancer group. The uptake of 3H-thymidine was markedly depressed in cancer patients when stimulated with various mitogens. There was little correlation between any of the stimulation tests and any of the lymphocyte subpopulation proportions to delayed hypersensitivity cutaneous reactions. Optimal proliferative response was found in lymphocytes stimulated with 10 micrograms of concanavalin-A and 10 microgram of phytohemagglutinin. Advanced stage patients had greatly depressed delayed hypersensitivity skin reactions and proliferative responses to mitogens compared with localized diseases. These results suggest that gastric cancer patients have depressed cellular immune functions, which mainly result from the decreased helper cells and defects in functional proliferative response to mitogens. Interleukin-2 and interferon-gamma restored the in vitro proliferative response of lymphocyte in patients with gastric cancer.

액정 함유(W/O)/W 에멀젼형 액막을 이용한 LD-라세믹체 아미노산으로부터 L 및 D 아미노산의 추출분리

김종국,김우식,이병철 연세대학교 산업기술연구소 1993 논문집 Vol.25 No.1

The purpose of this study is to separate each L-and D-amino acid from the racemic mixture of amino acid. which is obtained in chemical synthesis, using the liquid emulison membrane containing cholesteric liquid crystal. The LEM containing cholesteric liquid crystal was made according to kinds of cholesteric liquid crystal. And the selectivity of pure optical amino acid was obtained by extracting L and D-phenylalanine relatively, using the LEM containing cholesteric liquid crystal. When the optical activity of liquid ?? has negative value, the selectivity of D-phenylalanine was greater than that of L-phenylalanine in non-equlibrium state. But the selectivity disapperared as the process appoaches the eqilibrium of extraction and stripping.

골프 드라이버 스윙 임팩트 시 팔의 추가 당김이 클럽헤드 속도에 미치는 영향

김종숙,서국웅 釜山大學校 附設 體育科學硏究所 2005 體育科學硏究所 論文集 Vol.21 No.1

The purpose of this study was to find out variables to increase the golf driver distance through simulation analysis of the double pendulum model on computer. Also, it was performed in order to examine the effects of additional pull of the arm on the velocity of the clubhead in moment of the golf driver swing and provide the scientific basis for improving the skill of swing. The conclusions are as follows :........

八會血 應用의 經穴學的 硏究

金容佑,朴寅圭,林鍾國 圓光大學校 韓醫學硏究所 1992 원광한의학 Vol.2 No.1

Shu(수) point is the communication channel of meridian-viscera and body surface. It is used for the point acupuncture and moxibustion that the solid and hollow organs and meridians are closely related with each other. Also, that is point where the channel energy(脈氣) of meridian and viscera organs communicate inward and outward. Hence, the knowledge on the meridian and its points are essential for acupunture and moxibustion therapy. Especially, Palhoae point(八會穴) is one of the special points chiefly used for the remedy of faver. In this study, the use of Palhoae point(八會穴) is examined through the literatural survey.

MOCVD法에 의한 TiO_2 薄膜의 製造 및 特性

金鍾國,朴炳玉 경북대학교 산업기술연구소 1995 産業技術硏究誌 Vol.23 No.-

TiO_2 thin films were deposited on Si-wafer(100) using atmospheric-pressure chemical vapor deposition method. The used MO source material was titanium tetraiso-propoxide((Ti(OC_3H_7)_4, TTIP). The vapor of the organo-metallic precursor was carried by Ar gas and pure O_2 was used as reactant gas. The refractive index was measured by ellipsometry. The morphology and thickness of the deposited films were characterized by scanning electron microscope(SEM). From the results of thermodynamic prediction in the TTIP + Ar system, the effect of carbon in deposited film was restricted to reactant gas. When the substrate temperature was 300℃, the intensity changes of the cross section of the deposited films were observed by EPMA. From this result, it was confirmed that TiO_2 films were well deposited. The deposition rates of thin films increased with the oxygen content and the substrate temperature. Above 400℃, the deposition rates of thin films were controlled by mass transport. The refractive index increased with the substrate temperature. When excessive oxygen gas was supplied, the refractive index of deposited film was decreased. The refractive index was not affected by total flow rates.

감잎의 성장시기에 따른 화학성분 변화

김종국,이원영 동아시아식생활학회 2002 동아시아식생활학회지 Vol.12 No.1

In order to promote the utilization of persimmon leaf as food, chemical components in freeze dried Persimmon leaves were analyzed. The proximate composition was composed of moisture(79.65%), crude protein(17.97%), crude fat(1.33%), ash(2.37%), crude fiber(2.01%). During growth, moisture content was decreased and crude fat, crude fiber and ash were increased, respectively. Free sugar was composed of glucose, fructose, sucrose, raffinose. Nonvolatile organic acid contents were composed of oxalic acid, levulenic acid, malic acid and citric acid in the order. 18 amino acids of total amino acid in persimmon leaves were detected and major amino acid were glutamic acid, aspartic acid, leucine, phenylalanine, arginine and valine. The soluble tannin and vitamin C of persimmon leaves were 6859.37 ㎎% and 1487.12 ㎎%. During growth, its contents increased and then decreased after 20th june.

비정형 향정신병약물을 투여 중인 정신분열병 환자의 주관적 삶의 질 : 정신병리, 약물 부작용 및 약물에 대한 주관적 반응과의 관련성

김종훈,윤정희,이자영,노경희,홍성극,윤세창,강웅구,김용식 大韓神經精神醫學會 2003 신경정신의학 Vol.42 No.2

Objectives : The purpose of this study was to evaluate the characteristics of psychopathology, adverse drug effects, and Subjective response to drugs that have a significant impact on the subjective quality of life in schizophrenic patients receiving atypical antipsychotics. Methods : One hundred and one schizophrenic patients, who were receiving maintenance treatment with atypical antipsychotics, were evaluated. Subjective quality of life was assessed using the standardized Korean modification of a self-rating scale to measure subjective well-being under neuroleptics (KmSWN). Patients' psychopathology was evaluated using the Positive and Negative Syndrome Scale. Adverse effects and subjective response to drug were evaluated using the Liverpool University Neuroleptic Side Effect Rating Scale and the Drug Attitude Inventory-10, respectively. Correlation analysis and stepwise multiple regression analysis were conducted. Results : In psychopathology, the severity of depression and anxiety showed the most significant correlation with the score ofKmSWN. In adverse drug effects, the severity of psychic side effect and extrapyramidal side effect showed the most significant correlation with the score ofKmSWN. Regarding subjective response to drug, significant correlation was observed between the severity of subjective negative response and the score of KmSWN. Stepwise multiple regression analysis revealed that psychic side effect, extrapyramidal side effect, and depression contributed significantly to the total score of KmSWN. These variables accounted for 59.7% of the total variance. Conclusion : The results of the present study suggest that psychic side effect, extrapyramidal side effect and depressive symptom are the clinical characteristics that are significantly associated with the subjective quality of life. An effective management strategy for these variables should be established in developing a treatment program to enhance the quality of life of patients with schizophrenia.