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      • KCI등재후보

        리네졸리드와 반코마이신을 교대로 투여하여 치료한 지속성 메티실린 내성 황색포도알균 균혈증 1예

        김낙현,김문석,장은선,강유민,김가연,장희창,박완범,김의종,김남중,오명돈 대한감염학회 2009 감염과 화학요법 Vol.41 No.6

        Persistent Staphylococcus aureus bacteremia is frequently defined as bacteremia persisting for ≥7 days despite proper antibiotic therapy. Its treatment includes removal of all infection foci and proper antibiotic therapy. Vancomycin remains the antibiotic of choice in MRSA bacteremia. Alternative agents, linezolid or daptomycin, are available, but a consensus regarding management of persistent MRSA bacteremia on vancomycin failure is still lacking. We report a case of a 60-year-old male who received thoracoabdominal aorta replacement operation due to dissecting aneurysm of the ascending and descending aorta. Surgical site infection and bacteremia caused by MRSA occured, and wound debridement operations were performed. The patient was treated with vancomycin in therapeutic doses but MRSA bacteremia persisted for 168 days in a row. Although the inserted aortic graft was the most probable source of persistent bacteremia, surgical removal was impossible. Linezolid was administered as an alternative antibiotic but had to be discontinued from time to time due to thrombocytopenia induced by this agent. In the end, MRSA bacteremia was successfully managed by alternating vancomycin-linezolid therapy.

      • 다발성 대장암 간전이 환자의 간절제를 위한 새로운 시도

        주종우,김형철,임철완,신응진,조규석,유기원,송옥평,홍대식,박성진,조준희,이혜경,김희경,권계원,고은석 순천향의학연구소;Soonchunhyang Medical Research Institute 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

        Multiple bilobar liver matastases (MBLM) are the main cause of low resectability in the colon cancer liver metastases. The authors experienced one case of initially non-resectable colon cancer liver metastases. He was curatively and safely treated with a two-stage hepatectomy using the new method of future remnant liver volume growing. A 54-year-old man was referred to our department with the sigmoid colon cancer combined with MBLM, which were checked in two small metastatic lesions in the left lobe and five large sized lesions in the right lobe in the computed tomogram (CT). A laparoscopic assisted anterior resection was primarily performed. We performed the 1^(st) stage hepatectomy 3 weeks after the colon resection. Intra-operative Ultrasonogram (US) found 9 small superficial metastatic lesions in the left lobe. All that lesions were completely removed by non-anatomical wedge resection. An occlusion ballon catheter was placed in the right portal vein through a small branch of the inferior mesenteric vein at that time. The future remnant liver volume was sufficiently increased 3 weeks after the 1^(st) hepatectomy. A right hepatectomy was safely performed 22 days after the 1^(st) hepatectomy. The patient received a regional chemotherapy (interleukin2 based immuno-chemotherapy through hepatic artery) for 4 months, then received 9 cycles of systemic chemotherapy (biweekly Oxaliplation, leucovorin, plus 5-fluorouracil) without any recurrence evidence.

      • SCIESCOPUSKCI등재
      • SCOPUSKCI등재

        어린이의 사시교정술시 인공호흡수와 심박수와의 상관관계

        강종만,김종성,김희수,염명걸 대한마취과학회 2001 Korean Journal of Anesthesiology Vol.41 No.4

        Correlation between Respiratory Rates and the Degree of Bradycardia in Strabismus Surgery in Children Jong-Man Kang, M.D., Hee-Soo Kim, M.D., Chong0Sung Kim, M.D. and Myung-Kul Yum, M.D.^* Department of Anesthesiology, College of Medicine, Seoul National University, Seoul, and ^*Department of Pediatrics, College of Medicine, Hanyang University, Seoul, Korea Background: Strabismus surgery is frequent in pediatric ophthalmic surgery. Traction on the extra-ocular muscles can trigger an oculocardiac rdflex. We investigated the correlation between respiratoy rates and the degree of bradycardia to find another management for preventing oculocardiac reflex. Methods: NO premedications were administered. They were induced with thiopental and vecuronium and maintained with O_@-enflurane-N_2O. The tidal volume was 10 ml/kg. Respiratory rate of group 1 (n = 18) was fixed at 24 bpm, group 2 (n = 18) at 20 bpm, and group 3 (n = 19) at 16 bpm. We measured the mean heart rate from intubation to the beginning of surgery and defined this as the basal heart rate. We defined the lowest heart rate after traction of the extraocular muscles as the minimal heart rate. We calculated the correlation coefficient between the respiratory rate and basal heart rate, minimal heart rate, the change of heart rates and E_tCO_2. Results: There was a positive correlation between the respiratory rate and the basal heart rate, and minimal heart rate. There was no correlation between the respiratory rate and the change of heart rate. There was no difference in E_tCo_2 among the 3 groups. Conclusions: Can be increased both basal heart rate in anesthetized patients and minimal heart rate induced by oculocardiac reflex by making the respiratory rate more rapid if there is no significant difference of E_tCO_2. The oculocardiac reflex may be reduced by making respiratory rate more rapid if there is no significant influence on minute ventilation. (Korean J Anesthesiol 2001; 41: 450~454)

      • 변압기의 유동대전에 대한 유속 및 유온의 영향에 관한 연구

        정원용,고희석,박상현,박재윤,김정달 慶南大學校 附設 工業技術硏究所 1992 硏究論文集 Vol.10 No.-

        本 硏究에서는 固體-液體 界面에서 液體가 流動할 때 발생되는 유동대전에 대한 硏究로서 大容量 變壓器내에서 絶緣油가 통과하는 通路를 모델링한 帶電 파이프를 設計·製作하고 대전 파이프내의 油路形狀에 따른 流動電流를 側定·分析하였다. 이러한 實驗으로부터 얻은 결과는 다음과 같다. 1) 流動電流는 油速의 增加에 따라 線形的으로 增加하였으며, 油溫의 增加에 따라 약 46[℃]이하에서는 增加하고 그 이상에서는 感少한다. 2) 絶緣油의 흐름이 원활하게 되도록 油路形狀을 변화시키면 流動電流는 感少한다. In this paper, the streaming electrification generated at a solid-liquid interface is studied. Electrification pipe modeled on the oil path of the high power transformer is designed and manufactured. The Streaming current is measured as a function of oil velosity, temperature at each electrification pipe. From the result of this study the following conclusions are obtained. 1) The streaming current increases linearly with increasing of oil velocity and It increases at lower temperature than 46[℃]and decreases at higher temperature than 46[℃] 2) The smoother the flow of insulating oil is the less the streaming current decreases.

      • 人參 根腐病에 關한 硏究<第二報> : 人參圃 土壤中의 菌類에 垂直分布 및 菌種 分類에 대하여

        金倧熙,李敏雄 東國大學校 1974 論文集 Vol.13 No.-

        本 實驗은 人蔘圃 土壤中 根腐病이 發生한 곳과 發病않은 無病地 및 人蔘을 耕作않았든 土壤을 選定하여 捷息하는 菌類의 土壤別 垂直分包와 菌類를 分類하였고 土壤의 物理化學的 性質을 調査하여 다음과 같은 結果를 報告하고자 한다. 1. 土壤의 酸度는 各個 土壤이 均一하고 모두 酸性을 나타냈다. 2. 有機物의 含量은 5%의 有意差가 있어 無耕作地>羅病地>無病地와 같은 關係가 있다. 3. 無機物의 含量으로 CA과 Ksms 差異가 없고 P_2O_5와 Mg는 無病地와 蕪耕作地보다 5%의 有意差로 더 많이 함유하였다. 4. Cs와 Fs値는 無病地가 羅病地와 無耕作地 보다 5% 有意差로 差異가 있다. 5. Silt는 無病地가 他地區보다 더 적은 5%의 有意差가 있었다. 6. 水分含量은 統計的으로 差異이나 無病地에 比較的 적게 含有되엇다. 7. 菌類의 垂直分布는 一般的으로 各土壤 供히 表土層에 多數分布하는 경향이 있고 深層에 가까울수록 적어지는 경향이 있다. 統計的으로 無病地는 地區 보다 적으며 5%의 有意差가 있었다. 8. 羅病地 土壤은 10屬 21種의 菌腫이 分布하고 Aspergillus와 Penicillium屬이 多數分布하고 Rhizopus와 Nigrospora屬의 分布가 적었다. 9. 無病地는 12屬 17種으로 Asp. Pen. 및 Spicaria屬 등의 分布가 多數이고 Mucor Marrsonia 및 Rhizoctonia屬 등이 적게 분포하였다. 10. 無耕作地는 10屬 10種이 分布하고 Asp. Peb.屬이 多數分布하고 Hyalopus屬와 Thamnidium屬이 적게 分布하였다. This study was carried out March, 1973. the aim of this study was to know the relationship between soil conditions and population of vertical fungi distribution and species founded in the soil of uncultivated plot of ginseng diseased and healthy plot of ginseng in Kang wha-Gun, Korea. Acidity of each soil was uniformly acid. Organic matter content was 5 per cent significance in each soil; uncultivated plot was significance to diseased and healthy plot, and diseased plot was significance to healthy plot. As inorganic matter, Ca and K contents were uniform in all plot, but P_2O_5 and Mg were 5 per cent significance; healthy plot contain more quantity than the other two plot. Cs and Fs value were 5 per cent significance; healthy plot contatin more quantity than the other two plot. Silt was also 5 per cent significance; uncultivated and diseased plot contain more quantity than healthy plot. Moisture content was statistically uniform in all plot, but it was less in healthy plot. Numbers of fungi were largely distributed on the surface soil, and decrease with depth. As the numbers of fungi, healthy plot was significance to other two plot which cantain larger numbers. As to the species, diseased plot had 10 genera and 21 species, healthy plot had 12 genera and 17 species, and uncultivated plot had 10 genera 10 species. There was dominantly populated Aspergillus, Penicillum and Spicaria, but Rhizopus, Nigrospora, Marrsonia, Rhizoctonia, Hyalopus and Thamnidum group genera were recessively distributed.

      • 항생제 사용과 관련된 Clostridium difficile 감염증

        김홍빈,김남중,최희정,오명돈,김의종,최강원 대한화학요법학회 1997 대한화학요법학회지 Vol.15 No.1

        목적 : Clostridium difficile 감염증은 중요한 원내 감염중의 하나로 최근 들어 항균제 사용의 증가와 함께 그 빈도가 늘어나고 있어 Clostridium difficile 감염의 빈도 및 임상양상을 알기 위해 본 연구를 시행하였다. 방법 : 102명의 정상 성인으로부터 대변에서 Clostridium difficile 배양을 시행하였으며, 92년 3월부터 93년 9월까지 서울대학교 병원에 입원한 환자중 대변배양 검사에서 Clostridium difficile이 배양된 61명의 환자를 대상으로 병록지를 토대로 조사하였다. 결과 : 정상 성인 중 3%에서 Clostridium difficile이 분리되었다. 대상환자의 기저 질환은 악성고형종양(29%), 혈액종양(6.5%), 뇌혈관 질환(6.5%), 간경변(4.9%) 등의 순이었으며, 대상 환자의 75%에서 균이 분리되기 6주 이내에 항균제가 사용되었다. 사용된 항균제는 aminoglycoside(60.8%), 1세대 cephalosporin(56.5%), 3 세대 cephalosporin(43.4%), ampicillin(15.2%), metronidazole(15.2%), clindamycin(8.6%)의 순이었다. 흔한 증상은 설사(77%), 복통(53.8%), 오심(37%), 빈맥(25%) 등이었며, 혈액 검사상 백혈구증가증은 21.6%, 저알부민혈증은 3.03%에서 관찰되었다. 44명의 환자중 24명의 환자가 대증적 치료 후 호전되었고, vancomycin이나 metronidazole을 투여받은 17명의 환자중 15명의 환자가 증상의 호전을 보였다. 4예가 사망하였으며, 3예(4.9%)는 재발하였다. 결론 : Clostridium difficile 장염은 항균제 사용시 흔히 발생하는 질환이다. 정상 성인의 3%에서 Clostridium difficile이 분리되었다. Objective : Clostridium difficile gastrointestinal disease is an important nosocomial infection and is associated with antibiotic use. This study evaluated the incidence and clinical characteristics of Clostridium difficile infections. Methods : Stool specimens from 102 normal adults were cultured for Clostridium difficile. Sixty-one patients with Clostridium difficile isolated from stool specimens were reviewed retrospectively. The patients were seen at the Seoul National University Hospital during the period from Mar., 1592 to Sep., 1993. Results : Clostridium difficile was isolated in 3% (3/102) of normal adult Population. Underlying diseases of the patients included solid tumor(29%), hematologic malignancy(6.5%), corebrovascular disease(6.5%), and liver cirrhosis(4.9%). Antibiotics associated with Clostridium difficile infections included aminoglycosides (60.8%), first generation cephalosporin(56.5%), third generation cephalosporin(43.4%), ampicillin(15.2%), metronidazole(15.2%), and clindamycin(8.6%). In 3/4 of the cases, these antibiotics had beer) administered within 6 weeks before Clostridium difficile isolated. Associated symptoms included diarrhea(77%), abdominal pain(53.8%), nausea(37%), fever(37.7%), and tachycardia(25%). Leukocytosis and hypealbuminemia were observed in 21.6% and 30.3%. Out of 44 cases received symptomatic treatment, 54% (24/44) improved. Of 17 cases treated with metronidazole or vancomycin, 88% (15/17) improved. Four cases expired and 3 cases(4.9%)were relapsed. Conclusion : Clostridium difficile gastroenteritis is frequently associated with antibiotic treatment. Three percent of normal adult population had Clostridium difficile.

      • 在日 朝鮮人 姜桂重의 삶과 鬪爭

        鄭熙鐥,金仁德 順天靑巖大學 2001 論文集-順天靑巖大學 Vol.25 No.-

        HoSan, KangKyeJung was born on August 15, which is Korean Independence Day. He was an actionist to spend his life for the fraters and his country so that had been reached to a fraternity and a patriotism. As a Korean in Japan or Korean-Japanese in Korea, he stood without a peer. Ahead of time, he learned about a strong racial consciousness from his uncle, KangJinWon who was a chief of a righteous army. KangKyeJung fought as a leader of thousands armed Korean workers in SungJin factory against a discrimination and a mistreatment by Japanese. But also KangKyeJung worked for the Korean workers who were drafted from Hotkaido and were trodden down to rescue them. He worked for organizations and the fraters precedently than his private. He had never gave up for any business about the Korean Residents Union in Japan with any hard situation. After the war Korean-Japanese organizations were succeeded as one was JaeilbonChoseoninYeonmageng(在日本朝鮮人聯盟) - JaeilbonChoseonTongil Minjujeonseon(在日朝鮮統一民主戰線)-JaeilbonChoseoninChongyeonhabhoe(在日本朝鮮人總聯合會), the otherhand was ChoseonGeongugchogjinCheongnyeonDongmaeng(朝鮮建國促進靑年同盟) -JaeilbonChoseonGeoryunmindan(在日本朝鮮居留民團) - JaeilbonDaehanmingug Georyunmindan (在日本大韓民國居留民團) - The Korean Residents Union in Japan(在日本大韓民國民團) and some of the parts was succeeded IibonGongsandang Choseoninbu(日本共産黨朝鮮人部) -GogugBangwiwiwondhoe(祖國防衛委員會)- Gogug Bangwidae(祖國防衛隊), Undoubtedly, there were naturally prerequisited human interchanges between organizations. As roling a leader of The Koran Residents Union in Oosaka. He nomalized the Koran Residents Union and also organized the Korean Walfare Association that could be a role to solve the problems of fraters' mutual aid and union hall's registration. Also he had never stopped to support a material help to Korea in depression. Some of days KangKyeJung changed to a business man without any fund, he tried his new life only with his new ideas. He started from a rubber factory and had a hand in an organic business. He made prosperous his business with faithfulness, diligence and reliance that could be a basement of his recovery. KangKyeJung returned to Korea on August, 1957 just 20 years later and he made his mind to settle down in Korea permanently in 1981. KangKyeJung made every effort for Korean-Japanese and Korea, he was only who had limitations about a time and a spirit.

      • KCI등재후보

        기초도형과 색에 따른 시각감성 평가 : 대전과 대구지역의 대학생을 중심으로 Focused on the College Students of Daejeon and Daegu

        김묘향,윤종희 한국의류산업학회 2004 한국의류산업학회지 Vol.6 No.4

        We evaluate what kinds of differences are existed to the visual sensitivity of college students in Daegu and Daejeon. Evaluation used the produced basic pattern to change modeling element of figure, direction, proportion, and color. The results are as below. The circle is preferred to the figure sensitivity and the triangle in Daegu and triangle and quadrangle in Daejeon is disliked. The direction sensitivity shows the difference of preferences according to figure. The angle of 00 and 90?which could be felt stability is preferred in general. In proportion sensitivity, the basic figure 1:1 rectangular proportions are preferred. The color sensitivity I shows the differences of preference according to figure and there are difference to the area in the degree of aversion.

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