풍진항체 검사법의 신뢰도에 관한 연구 : Comparison of the Methods between the Abbott RUBAZYME kit and the Abboutt IMx Automated Analyzer

신영전,최보율,최은주,박항배 한양대학교 의과대학 1995 한양의대 학술지 Vol.15 No.2

Abbott Rubazyme and Abbott IMx, which are most used to prevent Rubella IgG and IgM thesedays, were evaluated for their reliability. Both methods were tested on 305 women, 287 and 18 number of each pregnant and non-pregnant women, in Yangpyong county from March 1993 through September 1993. In addition, they had 14. 3 weeks of pregnant period and 25.8 of average age. It appeared that there was a significant correlation between the titers of Rubazyme and IMx for Rubella IgG (Coefficient Correlation 0.6167, p=0.000) but not for IgM(C. C. 0.0668, p=0.245). Additionally, the correlation coefficient of the two methods for IgG titer of 1st and 4th quartile, 0.6829, p=0.000, were higher than that of 2nd and 3rd, 0.4600, p=0.000, So does IgM : 0.1081, p=0.181 for ist and 4th quartile and 0.0230, p=0.780 for 2nd and 3rd quartile. The agreement rate of positivity was 92.5% for IgG and 99.0% for IgM. The kappa index for IgG was 0.51338. The agreement point of titer, where the number of a people who showed positivity for IgG in IMx test and that in Rubazyme kit test became equal, was 31.3 IU/ml, which was 315% of the original point, 9.949 IU/ml. The agreement rate of both tests for 1gG was decreased to 92.13% but the kappa index was increased to 0.66869 in rasing cut off point of the IMx up to 31.3 IU/ml. Abbott Rubazyme and Abbott IMx tests play important roles in determining the infection of pregnant women and even the prevention of deformation of child and artificial abortion. However, since these two methods turns out not to be reliable to be used through this experiment, physicians should examine the reliability of both methods, and even the possibility of technical errors of them before actual use.

교사가 지각하는 유치원 직무만족도에 관한 연구

신인숙,최보영 啓明大學校 生活科學硏究所 2002 科學論集 Vol.- No.-

The purpose of this study was to examine the level of job satisfaction of kindergartens teachers to find out problems there. For this study, participants were 92 teachers from public kindergartens and 132 teachers from private kindergartens in Dae-gu and Kyung-book areas and the questionnaire made by Jorde - Bloom(1988) was used. Surveys with variables such ad kind public or private kindergarten, status(married or unmarried), position, age, rank, educational back ground, career, position, certificate, number of classes, and number of student in kindergartens were carried out. The results obtained were discussed with the variables. The total level of work satisfaction of the teachers was 62.6 persent. The grade indicates that the level of satisfaction is acceptable.

무전해도금에 의한 다공성 니켈의 제조에 관한 연구

신준호,김기원,허보영 국립경상대학교 공과대학 부설 첨단소재연구소 1993 尖端素材 Vol.3 No.-

A new process on the preparation of porous nickel by electroless plating was developed using fine graphite powders of 1㎛-2㎛ particle diameter and polyurethane foam. In this process, graphite powders were introduced into the pores(foams) existing within polyurethane foam in order to supply electric conducting seeds for nickel deposition by electroless plating reaction. After the electroless plating, remaining polyurethane was removed chemically using organic solvent and most of graphite powder seeds also removed by ultrasonic cleaning. Porous nickel plates with 250㎛-300㎛ thickness and porosity comparable to commercial sintered nickel plate were obtained and found out that the platesare of mono-layer structure composed of spherical nickel particles connected each other in two-dimensional scale.

흉부 위국소화 감각 수준으로 발현된 경부 추간판 탈출증

이보람,조동신,윤신구,조상걸,안무영,성기범 대한신경과학회 1999 대한신경과학회지 Vol.17 No.5

알코올 금단 발작 환자에서 진전 섬망 예방에 대한 Nimodipine과 Chlordiazepoxide의 효과 비교

정두신,양광익,이보람,방차옥,이태경,성기범,안무영,박형국 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.1

Background & objectives : An increase of calcium influx during alcohol withdrawal state may contribute to neuronal hyperexitability, which cause delirium tremens(DT). Some investigators have found calcium channel blockers effects in prevention of DT in experimental animals. Therefore we evaluated the preventive effects of calcium channel blocker(nimodipine) and benzodiazepine(chlordiazepoxide) on the development of DT in alcohol withdrawal seizure(AWS) patients. Method : A total 59 patients with AWS were divided into three groups according to the management nimodipine-treated, chlordiazepoxide-treated, and control(no specific medication) groups. We compared the incidence rates of DT in the three groups. Results : Total incidence rate of DT was 30.5%(18 of 59 patients). There were 6 DTs of 18 patients(33.5%) in nimodipine-treated group, 4 of 21 patients(22.5%) in chlordiazpoxide-treated group, and 8 of 20 patients(44.0%) in control. Conclusion : The control group(44.0%) showed the highest incidence rate of DT. And nimodipine-treated(33.5%) and chlordiazepoxide-treated group(22.5%) were followed. However, this result failed to demonstrated statistically significant differences due to small numbers size.

Streptococcus mutans의 gtfD 유전자 발현에 대한 이온 및 완충액의 영향

김보영,김신,정진 大韓小兒齒科學會 2004 大韓小兒齒科學會誌 Vol.31 No.2

글루캔 형성은 이온, 완충액 및 영양물질 등과 같은 구강 내 존재하는 물질과 이들의 변화에 영향을 받는다. 본 연구에서는 치아 우식증의 중요한 원인균인 Streptococcus mutans를 실험균으로 하여 수용성 글루캔 합성 요소인 GTFD 유전자의 발현에 대한 이온 및 완충액의 영향을 Fluorescent in situ hybridization 방법으로 관찰하여 다음의 결과를 얻었다. 1. CaCl₂ 농도가 1.0mM, KCl 농도가 2.5mM, MgCl₂의 농도가 0.4mM일 때 생균수가 가장 많았다. 2. 완충액의 경우 sodium bicarbonate 10mM, sodium phosphate, 1mM, potassium phosphate 0.1mM에서 생균수가 가장 많았고, 3가지 완충액 모두 100mM 농도에서 생균수가 가장 적었다. 3. 자당이 함유되지 않은 BHI 배지에 비해 1% 자당을 첨가한 경우 gtfD 유전자의 mRNA 발현에 따른 녹색형광이 관찰되었다. 4. CaCl₂ 0.25mM 일 때 gtfD 유전자 mRNA 발현에 따라 녹색형광이 대조군보다 강하였고, KCl의 경우 10mM 일 때 대조군과 유사한 녹색형광을 나타냈으나, 다른 농도에서는 거의 관찰되지 않았다. MgCl₂의 경우 각 농도에서 대조군보다 녹색형광이 약하게 나타났다. 5. Sodium bicarbonate, sodium phosphate 완충액의 경우 mRNA 발현에 따른 녹색형광이 각 농도에서 대조군과 유사하게 나타났으며, potassium phosphate 완충액의 경우 100mM에서 녹색형광을 거의 관찰할 수 없었다. The production of a glucan was affected by the concentration of ions and buffer solutions, and nutrients in an oral cavity. In this study, the effects of ions and buffer solutions on the mRNA expression of gtfD gene in Streptococcus mutans, an important causative agent of dental caries, were investigated by Fluorescent in situ hybridization(FISH). At fist, ions and buffer solutions had little effect on the multiplication of Streptococcus mutans. The green fluorescence according to the mRNA expression of gtfD gene was detected in the BHI broth containing 1% sucrose. The intensities of the green fluorescence were strong at 0.25mM of CaCl₂ Little fluorescence was detected by the addition of KC1, except for l0mM KC1 at which fluorescence intensities were similar to those of the control. Fluorescence intensities were weak at each concentration of MgCl₂ when compared to the control. As for buffer solutions, fluorescence intensities were similar to those of the control at each concentration of buffer solutions, except that they were little detected at l00mM of potassium phosphate.

GIS를 이용한 산불발생위험지역 구분

이시영,안상현,원명수,이명보,임태규,신영철 한국지리정보학회 2004 한국지리정보학회지 Vol.7 No.2

산불로 인한 재해를 미연에 방지하고 피해를 저감하기 위해서는 산불발생위험지역을 사전에 파악하여 예방대책을 세울 필요가 있다. 따라서 본 연구에서는 산불발생인자에 따른 산불발생위험지역을 구분하고자 겸상북도 의성군에서 발생한 산불피해지역에 대하여 임상, 지형 등에 대하여 조사하였다. 조사된 요인들 간 독립성 유무를 상관분석을 이용하여 산불발생과 관련 있는 7개의 주제도를 선정하였으며, 선정된 주제도를 조건부확률과 지리정보시스템을 이용하여 산불발생확률을 계산하였다. 계산된 산불발생확률을 20개 등급으로 지수화하여 산불발생위험지역을 구분하였다. In order to decrease the area damaged by forest fires and to prevent the occurrence of forest fires, we are making an effort to improve prevention measures for forest fires. The objective of this study is to classify hazard regions where forest fires occur based on the factors that contribute to the occurrence of forest fires. Forest fire sites in the Uiseong-gun, Gyeongsangbuk-do were surveyed according to the factors of forest type and topographic characteristics where the forest fires occurred. We used a correlation analysis to determine the forest fire occurrence factors and a conditional probability analysis and GIS to determine a forest fire danger index. The resulting forest fire danger index was used in the classification of forest fire occurrence risk regions.

산불 豫防을 위한 放火線 및 耐火樹林帶 組成에 關한 歷史的 考察 : 朝鮮時代부터 日帝强點期를 中心으로 During the Joseon Dynasty and Japanese Colonial Period

姜永鎬,林柱勳,辛壽哲,李明甫 한국임학회 2004 한국산림과학회지 Vol.93 No.7

조선시대부터 일제강점기에 이르는 시기의 산불억제 및 예방시설에 관한 사료를 수집하여 임업기술 사적인 고찰을 하였다. 조선시대에는 방화선 위주로 설치하였는데 이는 주로 묘역보호를 위하여 화소(火巢)라고 하는 인종의 흙제방을 축조하거나 도성 및 종묘와 같은 특정 건물 보호를 위해 일정한 폭으로 소나무숲의 벌채가 이루어지기도 하였다. 구한말시대에 이르러서야 비로소 본격적인 산림보호를 위한 방화선이 설치되기 시사하였으며 일제강점기에 이르러서 설치비용과 관리인력을 다수 필요로는 방화선의 단점을 보완한 내화수림대 설계안이 일부 지방을 대상으로 작성하여 세시하기에 이른다. The historical reports related to the fire line and firebreaks from the period of the Joseon Dynasty to Japanese colonial period were reviewed. In the Joseon Dynasty era, a kind of ditch named Whaso was built on the boundary of the royal mausoleum, and pine trees were cut down to protect castle towns and the Chongmyo from wildfire. In the late Great Han Empire period, fire lines were installed around the water conservation forests to reduce the fire risks. During the Japanese colonial period, several detailed designs for firebreaks were drawn up and the fire-resistant species were selected by introducing of the concept on firebreaks.

네모나프라이드의 유효성 및 추체외로 부작용 : Haloperidol 및 Risperidone과의 자연관찰적 개방형 비교연구 A Naturalistic Open Comparative Study with Haloperidol and Risperidone

서영수,김용관,신동환,공보금,이정구,박정환,윤성환,정치영,이상경,김영훈 대한생물치료정신의학회 2001 생물치료정신의학 Vol.7 No.2

Objectives : This open prospective study was performed in order to evaluate the efficacy and extrapyramidal adverse effects of nemonapride in the schizophrenic patients, and was compared wit one of typical antipshchotics. haloperidol and one of atypical antipsychotics, risperidone. Methods : Thirty male and female schizophrenic patients(DSM-Ⅳ) were treated for 12 weeks with haloperidol(n=10), risperidone(n=10) and nemonapride(n=10). The overall efficacy was assessed at baseline, 1st week, 2nd week, 4th week, 8th week, and 12th week by the Positive and Negative Syndrome Scale for Schizophrenia(PANSS). Also the overall safety was assessed in the same time period by the Extrapyramidal Symptom Rating Scale(ESRS). Results : There were no significant differences in PANSS scores(total, positive, negative, and general psycho­pathology subscale) among haloperidol, risperidone, and nemonapride groups, Treatment responders, defined as at least 20% reduction of baseline total PANSS score, were achieved by 8 patients(80%) in haloperidol group, 10 patients(100%) in risperidone group, and 8 patients(80%) in nemonapride group. And there were no significant differences in ESRS total scores among haloperidol, risperidone, and nemonapride group. Inter-group comparison among haloperidol, risperidone and nemonapride group, as assessed by the ESRS, revealed no significant differences in the shifts to the maximum score, 9.4(±9.4), 6.2(±8.4), and 11.3(±8.1) respectively, and also revealed no significant differences in the mean time reaching the maximum score, 4.5(±4.5) week, 7.8(±4.8) week, and 4.6(±4.4) week, respectivily. Conclusion : There wee no significant differences in the efficacy and extrapyramidal adverse effects among haloperidal, rispecridone and nemonapride groups. These results suggest that nemonapride was as efficacious and safe in he treatment of schizophrenia, as well known and widely used antipsychotics, haloperidol and risperidone.

한국의 학교보건 향상을 위한 시안

최보율,김지미,신영전,남정현 漢陽大學校 精神健康硏究 1997 精神健康硏究 Vol.16 No.-