성인에서 발견된 Nesidioblastosis 2예

황희승,박정현,강창일,김상효,최석진,김찬환 인제대학교 1997 仁濟醫學 Vol.18 No.3

Nesidioblastosis는 영아기의 고인슐린성 저혈당의 원인으로는 흔하지만 성인에서는 매우 드문 질환으로 되어 있다. Nesidioblastosis의 병리학적 특징은 췌장 전반에 다초점성 소관도 증식(multifocal ductuloinsular proliferation)을 보이는 것이다. 저자들은 반복되는 의식 소실과 전신 쇠약감, 두통 등을 보인 환자에서 수술 후 병리조직 소견상 Nesidioblastosis로 진단된 2예를 경험하였기에 보고하는 바이다. Although nesidioblastosis can be found frequently in neonates with hypoglycemia, it is regarded as an extremely rare entity that causes hyperinsulinemic hypoglycemia in adult. Pathologic characteristics can be described as multifocal hyperplasia of all pancreatic islet cells and their disorganization with proliferation throughout the entire pancreas. We experienced two cases of nesidioblastosis which caused hyperinsulinemic hypoglycemia in adult. Two female patients(49-year old and 58-year old) were admitted due to persistent hypoglycemic symptoms. Hyperinsulinemic hypoglycemia was documented by fasting blood sugar/insulin ratio. We performed ultrasonography. CT scan, angiography and percutaneous portal venous sampling in the first case. Radiologic imaging studies could not reveal definite mass lesion in pancreas, but insulin gradient in portal vein indicated possible insulinoma to rated between body and head of pancreas. The intraoperative ultrasonography and manual palpation, however, did not reveal any mass lesion. Near tonal pancreatectomy was done and pathologic specimen was confirmed to nesidioblastosis. In the second case, angiography revealed hypervascular mass which looked like lesion in pancreatic body, so we did not perform further studios including percutaneons portal venous sampling and calcium infusion angiography. But surgical exploration inculding intraoperative ultrasonography did not reveal any mass lesion. Subtotal pancreatectomy was done and pathologic specimen was also confirmed to nesidioblastosis.

단일 병원에서 소아 중환자의 예후인자 예측을 위한 PIM2 (pediatric index of mortality 2)와 PRIMS III (pediatric risk of mortality)의 유효성 평가 - 후향적 조사 -

황희승,이나영,한승범,곽가영,이수영,정승연,강진한,정대철 대한소아청소년과학회 2008 Clinical and Experimental Pediatrics (CEP) Vol.51 No.11

Purpose:To investigate the discriminative ability of pediatric index of mortality 2 (PIM2) and pediatric risk of mortality III (PRISM III) in predicting mortality in children admitted into the intensive care unit (ICU). Methods:We retrospectively analyzed variables of PIM2 and PRISM III based on medical records with children cared for in a single hospital ICU from January 2003 to December 2007. Exclusions were children who died within 2 h of admission into ICU or hopeless discharge. We used Students t test and ANOVA for general characteristics and for correlation between survivors and non-survivors for variables of PIM2 and PRISM III. In addition, we performed multiple logistic regression analysis for Hosmer-Lemeshow goodness-of-fit, receiver operating characteristic curve (ROC) for discrimination, and calculated standardized mortality ratio (SMR) for estimation of prediction. Results:We collected 193 medical records but analyzed 190 events because three children died within 2 h of ICU admission. The variables of PIM2 correlated with survival, except for the presence of post-procedure and low risk. In PRISM III, there was a significant correlation for cardiovascular/neurologic signs, arterial blood gas analysis but not for biochemical and hematologic data. Discriminatory performance by ROC showed an area under the curve 0.858 (95% confidence interval; 0.779-0.938) for PIM2, 0.798 (95% CI; 0.686-0.891) for PRISM III, respectively. Further, SMR was calculated approximately as 1 for the 2 systems, and multiple logistic regression analysis showed χ2 (13)=14.986, P=0.308 for PIM2, χ2 (13)= 12.899, P=0.456 for PRISM III in Hosmer-Lemeshow goodness-of-fit. However, PIM2 was significant for PRISM III in the likelihood ratio test (χ2 (4)=55.3, P<0.01). Conclusion:We identified two acceptable scoring systems (PRISM III, PIM2) for the prediction of mortality in children admitted into the ICU. PIM2 was more accurate and had a better fit than PRISM III on the model tested. (Korean J Pediatr 2008;51:1158-1164) Purpose:To investigate the discriminative ability of pediatric index of mortality 2 (PIM2) and pediatric risk of mortality III (PRISM III) in predicting mortality in children admitted into the intensive care unit (ICU). Methods:We retrospectively analyzed variables of PIM2 and PRISM III based on medical records with children cared for in a single hospital ICU from January 2003 to December 2007. Exclusions were children who died within 2 h of admission into ICU or hopeless discharge. We used Students t test and ANOVA for general characteristics and for correlation between survivors and non-survivors for variables of PIM2 and PRISM III. In addition, we performed multiple logistic regression analysis for Hosmer-Lemeshow goodness-of-fit, receiver operating characteristic curve (ROC) for discrimination, and calculated standardized mortality ratio (SMR) for estimation of prediction. Results:We collected 193 medical records but analyzed 190 events because three children died within 2 h of ICU admission. The variables of PIM2 correlated with survival, except for the presence of post-procedure and low risk. In PRISM III, there was a significant correlation for cardiovascular/neurologic signs, arterial blood gas analysis but not for biochemical and hematologic data. Discriminatory performance by ROC showed an area under the curve 0.858 (95% confidence interval; 0.779-0.938) for PIM2, 0.798 (95% CI; 0.686-0.891) for PRISM III, respectively. Further, SMR was calculated approximately as 1 for the 2 systems, and multiple logistic regression analysis showed χ2 (13)=14.986, P=0.308 for PIM2, χ2 (13)= 12.899, P=0.456 for PRISM III in Hosmer-Lemeshow goodness-of-fit. However, PIM2 was significant for PRISM III in the likelihood ratio test (χ2 (4)=55.3, P<0.01). Conclusion:We identified two acceptable scoring systems (PRISM III, PIM2) for the prediction of mortality in children admitted into the ICU. PIM2 was more accurate and had a better fit than PRISM III on the model tested. (Korean J Pediatr 2008;51:1158-1164)

First Report of the Mantid Shrimp Faughnia formosae (Stomatopoda: Parasquillidae) from Korea

황희승,이상규,김미진,김원 한국동물분류학회 2013 Animal Systematics, Evolution and Diversity Vol.29 No.3

The stomatopods are aggressive predatory marine crustaceans, which are mainly found in tropical and subtropical regions. Among these, a parasquillid stomatopod, Faughnia formosae Manning and Chan, 1997, collected from Jeju Island, is reported for the first time in Korea. The family is easily distinguished from other families by the presence of an asymmetrically bilobed cornea, stout propodus on the raptorial claw, and three primary spines of the uropodal protopod. In the paper, detailed descriptions and illustrations of this species are provided alongside a photograph. A key to the species of Korean mantis shrimp is also presented. As a result of this study, four species of stomatopods including this species are now recorded in Korean fauna.

New Record of a Gonodactylid Species, Gonodactylaceus falcatus (Crustacea: Stomatopoda: Gonodactylidae) from Korea

황희승,박태서,김원 한국동물분류학회 2018 Animal Systematics, Evolution and Diversity Vol.34 No.2

A gonodactylid stomatopod, Gonodactylaceus falcatus (Forskål, 1775), collected from Jeju Island is reported for the first time in the Korean fauna. The genus Gonodactylaceus, which is also new to Korea, differs from other genera by the presence of a subglobular cornea, five longitudinal dorsal carinae on the telson, and the absence of a movable proximal spine on the propodus of the raptorial claw. Within genus Gonodactylaceus, G. falcatus can be easily distinguished from other congeners by the presence of a bilobed knob on the telson, a rounded anterolateral margin of rostral plate, and a lobe between terminal spines of uropodal protopod. In this paper, detailed descriptions and illustrations of G. falcatus are provided. As a result of this study, seven species of stomatopods including this species are now recorded in the Korean fauna. A key to the species of Korean mantis shrimp is also presented.

환경DNA를 이용한 유해해양 및 교란 저서동물의 메타바코드 서열 분석 I

황희승,김한울,이정희,이택준,신숙,정종우 한국환경생물학회 2020 한국환경생물학회 학술대회 Vol.2020 No.07

조기위암과 동반된 막성신병증 1예

황희승,김양욱,김영훈,윤혀경 대한신장학회 1997 춘계학술대회 초록집 Vol.1997 No.-

Enterovirus 71에 의한 급성 파종성 뇌척수염 1례

황희승,조성희,김선미,정대철,정승연,강진한,Hwang, Hui Sung,Cho, Sung Hee,Kim, Sun Mi,Jung, Dae Chul,Chung, Seung Yun,Kang, Jin Han 대한소아감염학회 2003 Pediatric Infection and Vaccine Vol.10 No.1

본 저자들은 상기도 감염 후 발열과 배뇨곤란, 하지의 근력저하를 주소로 내원한 7세 환아에서, 급성 횡단성 척수염 증상으로 시작하여 의식 변화와 호흡부전의 급성 파종성 뇌척수염으로 진행한 1례에서 enterovirus 71을 증명하고 고용량 methylprednisolone 정주 후 증상의 호전을 경험하였기에 문헌 고찰과 함께 보고하는 바이다. Acute transverse myelitis is a focal inflammatory disorder of the spinal cord, resulting in motor, sensory, and autonomic dysfunction which would be the initial manifestation of acute disseminated encephalomyelitis. A 7-year-old boy developed weakness of lower extremities associated with dizziness and urinary dysfunction after upper respiratory infection. He showed gradual decreased mental status with respiratory difficulty. Spinal MRI showed diffuse spinal cord swelling from C3 to C7 levels with high signal intensity lesion on T2-weighted image, which is involved central gray matter of spinal cord from C3 to C7, proximal portion to cervicomedullary junction, and distal portion to the cornus medullaris. After the supplement of high dose intravenous methylprednisolone therapy with ventilator care, he showed gradual improvement. The brain MRI after extubation showed multifocal high signal intensity lesions in bilateral cerebral white matter on axial T2-weighted image. Immunoserologic test(neutral antibody test) for enterovirus 71 was positive. Dysfunction of the bladder lasted for 33 days. We report a case of transverse myelitis which progressed to acute disseminated encephalomyelitis by enterovirus 71 in a 7-year-old boy with related literatures.

태풍 시 케이블교량의 진동사용성 평가

황희승(Hwang, Eui-Seung),황민태(Hwang, Min-Tae),박기정(Park, Ki-Jung) 한국강구조학회 2021 한국강구조학회 학술대회 발표집 Vol.32 No.1

GPS를 이용한 스마트폰 블로그 서비스 개발

황희승 ( Hee-seung Hwang ),장지수 ( Ji-su Chang ),최성원 ( Sung-won Choi ),한익주 ( Ik-ju Han ),노영주 ( Young J Rho ) 한국정보처리학회 2010 한국정보처리학회 학술대회논문집 Vol.17 No.2

스마트폰이 활성화 되면서 자신만의 콘텐츠(사진, 글, 메모)를 스마트폰에서 작성하는 경우가 많아지게 되었다. 하지만 맛 집이나 데이트 코스 같은 핫스팟을 담은 콘텐츠를 블로그를 통해 공유하고 싶지만 그 방법이 한정되어 있다. 본 논문에서 다루는 GPS 블로그 서비스는 스마트폰에서 직접 블로그로 업로드 함으로써, 콘텐츠에 포함된 위치 정보를 블로그에 보다 빠르게 공유할 수 있다. 또한 현재 위치 정보를 맵을 통해서 블로그에 포스팅되기 때문에, 핫 스팟을 운영하는 업체 및 기업의 홍보를 보다 쉽게 가능하게 하는 효과가 있다.

상복부 통증이나 압통을 동반한 일차성 두통 환아들의 임상 양상

황희승(Hui Sung Hwang),최혜선(Hye Sun Choi),빈중현(Joong Hyun Bin),김영훈(Young Hoon Kim),이인구(In Goo Lee),정승연(Seung Yun Chung) 대한소아신경학회 2008 대한소아신경학회지 Vol.16 No.2

목 적 : 편두통 또는 두통과 위장관 증상과의 관련성이 보고되고 있다. 일차성 두통 환아들에 있어서 상복부 통증이나 압통을 동반하는 경우와 동반하지 않는 경우에서의 두통의 임상 양상과 치료에 대한 반응을 알아보고자 하였다. 방 법 : 2006년 1월 1일부터 2007년 12월 31일 사이에 1달 이상의 반복되는 두통을 주소로 인천성모병원에 내원한 환아들 중 ICHD-II(2004) 분류에 의해 일차성 두통으로 진단된 58례를 대상으로 하여 두통과 위장관 증상의 동반 유무에 따른 두통의 임상양상과 치료에 대한 반응에 대해 의무기록을 통한 후향적 조사를 하였다. 결 과: 일차성 두통은 편두통 22례, 긴장형 두통 34례, 분류되지 않는 두통 2례 중 상복부 통증이나 압통을 동반한 경우는 편두통 8례(36%), 긴장형 두통 17례(50%), 분류되지 않는 두통 2례(100%) 였다. 상복부 통증이나 압통을 동반한 편두통이나 긴장형 두통 군에서 동반하지 않는 각각의 군에 비해 여아의 비율이 현저하게 높았다. 두통의 정도는 상복부 통증이나 압통을 동반한 편두통과 긴장형 두통 군이 동반하지 않는 각각의 군보다 두통의 정도가 심한 양상을 보였다. 치료에 대한 반응으로는 상복부 통증이나 압통을 동반하지 않는 편두통과 긴장형 두통 군은 생활습관, 수면 습관, 식이 조절과 간헐적인 진통제만으로 두통이 호전을 보인 예가 각각 71 %, 94 %로 높았으나, 상복부 통증과 압통을 동반한 편두통과 긴장형 두통 군은 12%, 18%만이 호전되었으며, 규칙적인 제산제를 추가한 후 두통이 소실되는 경향을 보였다(64%, 53%). 분류되지 않는 두통의 경우 중증의 두통을 호소하였으며, 모두 상복부 압통을 동반하였으며, 규칙적인 제산제를 복용한 후 두통이 소실되었다. 결 론 : 일차성 두통을 가진 환아들 중 상복부 통증이나 압통을 가진 환아들에게서 생활 습관과 식이 조절 개선과 규칙적인 제산제 투여로 두통이 호전되었으며, 이는 두통을 유발하는 스트레스 요인과 관련된 위장관 증상의 조절에 의한 것으로 생각되며, 향후 스트레스 요인 분석과 적극적인 위장관계 검사를 통하여 두통과의 연관성을 확인하는 것이 필요할 것이다. Purpose : Population-based studies have shown positive associations between migraine and irritable bowel syndrome, colitis and peptic ulcer and migraine prevalence was higher among patients with dysmotility-like dyspepsia or nausea/vomiting. The aim of this study was to investigate clinical manifestation between primary headache with epigastric pain or tenderness(EPT) and primary headache without EPT. Methods : We retrospectively reviewed the medical records of 58 patients who were diagnosed primary headache[by ICHD-II(2004)] at Incheon St. Mary Hospital from January, 2006 to December, 2007. Their clinical characteristics such as age, sex, frequency & severity of headache and associated symptoms & signs were analysed. Results : The rate of headache associated with EPT were 36% of migraine cases, 50% of tension-type headache cases, and 100% of unclassified headache cases. Headache with EPT were at a high rate in female. Headache with EPT were more severe than one without EPT. Regulation of behavior, diet and sleep pattern had improved severity of headache in 71% of migraine without EPT and 94% of tension-type headache without EPT, but in 12% of migraine with EPT and 18% of tension-type headache with EPT. Headache disappeared in 64% of migraine with EPT and 53% of tension-type headache by additional regular antiacid medication. Conclusion : Our study supports any specific correlation between headache and EPT, but further studies are needed.