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Cytomegalovirus-Associated Severe Direct Antiglobulin Test Negative Hemolytic Anemia: A Case Report
홍현정,조영혜,임재영,염정숙,박지숙,박은실,서지현,우향옥,윤희상 대한소아혈액종양학회 2018 Clinical Pediatric Hematology-Oncology Vol.25 No.2
Cytomegalovirus is a common virus that is mostly asymptomatic when infected, but rarely causes life-threatening hemolysis especially in immunocompromised children. We report a case of antiglobulin test negative severe hemolytic anemia caused by cytomegalovirus infection developed in an immune competent 9-year-old girl. The patient’s hemoglobin level was 4.8 g/dL on the day of admission. The diagnosis was achieved by exclusion of other causes of hemolytic anemia and serological evidence of recent CMV infection. The patient was successfully treated with anti-viral agents and steroids resulting in recovery from anemia. Clinicians should consider cytomegalovirus infection in the differential diagnosis of hemolytic anemia in pediatric patients.
항 Signal Recognition Particle (신호인식입자) 항체와 연관된 근병증
홍현정,선우일남,신하영,김세훈,조정희,김승민 대한신경과학회 2011 대한신경과학회지 Vol.29 No.3
Myopathies associated with anti-signal-recognition particle (SRP) antibodies usually present with severe muscle weakness and exhibit necrotizing myopathy with little inflammation pathologically. Here we report a case of a 61-year-old man who presented with subacute progressive proximal muscle weakness, dysarthria, and dysphagia. Although polymyositis was expected clinically, muscle biopsy revealed myopathic changes with degenerating fibers without definite inflammation. Further laboratory study revealed that the patient was positive for anti-SRP antibodies.
보제소독음(普濟消毒飮)의 진통(鎭痛), 해열(解熱), 소염(消炎), 항균(抗菌) 및 항경련(抗痙攣)에 대한 실험적(實驗的) 연구(硏究)
홍현정,이한철,Hong Hyun-Jung,Lee Han-Cheul 대한한방소아과학회 1995 대한한방소아과학회지 Vol.9 No.1
Experimental studies were done to research the clinical effect of Bojeosodokeum on the Analgesic, Antipyretic, Anti-inflammatory, Antimicrobial and Anti-convulsive effects in mice and rats. The results obtained as follows : 1. The solid extract powders of Bojeosodokeum was revealed significant action on analgesic effect. 2. the solid extract powders of Bojeosodokeum was revealed significant action on Anti-inflammatory effect. 3. The solid extract powders of Bojeosodokeum was revealed significant action on antipyretic effect. 4. Antimicrobial effects of solid extract powders of Bojeosodokeum against Escherichia coli and staphylococcus aureus was observed. 5. The solid extract powders of Bojeosodokeum was revealed significant action on anticonvulsive effect. According to the above results, it is confirmed that analgestic, anti-inflammatory, antipyretic, antimicrobial and anticonvulsive effect were recognized in solid extract powders of Bojeosodokeum.
한국 노인의 일일 수분섭취 상태에 따른 주요 만성질환 유병률 및 탈수 예측 생리적 지표 탐색 연구: 2015년 국민건강영양조사 결과를 바탕으로
홍현정,김나현 기초간호학회 2018 Journal of korean biological nursing science Vol.20 No.2
Purpose: The aim of this study was to explore the prevalence of major chronic diseases related to daily oral water intake and to identify the physiological parameters related to dehydration in Korean elderly. Methods: The data were collected from the sixth Korea Health and Nutrition Examination Survey (KHANES), which was a nationwide and cross-sectional survey in 2015. We analyzed 1,392 participants using t-test and logistic regression. All participants were divided into the adequate water intake (AWI) group and the non-adequate water intake (NAWI) group based on the dietary reference intakes for Koreans. Results: There was a significant difference in the water intake between the AWI (6.8 cups in a day) and NAWI (2.8 cups) groups (p<.001). There was no statistically significant association between the level of water intake and any of the major chronic diseases. Blood urea nitrogen (BUN) and BUN/Creatinine (Cr) ratio were significantly higher in the NAWI group. Especially, BUN/Cr ratio shows that the NAWI group reached dehydration status. Older age (adjusted odd ratio, OR=1.07, 95% confidence interval, CI [1.04-1.10]), female gender (adjusted OR=1.56, 95% CI [1.05-2.33]), lower body mass index (BMI) (adjusted OR=1.00, 95% CI [0.92-1.00]), higher BUN (adjusted OR=1.04, 95% CI [1.01-1.08]), and higher urine specific gravity (USG) (adjusted OR=1.56, 95% CI [1.19-2.05]) were factors associated with the NAWI group. Conclusion: The findings suggest that the level of water intake needs to be considered in relation to age, gender, BMI, BUN, and USG. These are sensitive physiological parameters used for predicting dehydration of the elderly according to their daily oral water intake. It would be helpful to develop strategies to prevent dehydration in elderly individuals and enhance their water intake.
양육태도가 청소년의 성의식 및 태도에 미치는 영향: 청소년 인권의식의 매개효과
홍현정 한국청소년복지학회 2018 청소년복지연구 Vol.20 No.4
The purpose of this study is to identify the effect of the main caregiver’s parenting attitude which adolescents perceived on adolescents’ sexual consciousness and sexual attitude, focusing on the mediating effects of the adolescent’s perception of the human right. Students from middle schools in Busan city responded to the questionnaire. 469 questionnaire were statistically analyzed. The results of this study are summarized as follows. First, adolescents’ perception of the human right had a partial mediating effect on the relationship between the main caregiver’s receptive parenting attitude and the adolesent’s sexual consciousness and sexual attitude. Second, the adolescent’s perception of the human right had a partial mediating effect the relationship between the main caregiver’s autonomous parenting attitude and the adolescent’s sexual consciousness and sexual attitude. Based on these findings, this study suggests methods to improve the main caregiver’s parenting attitude and the adolescent’s perception of the human right. 본 연구는 청소년이 지각한 주양육자의 양육태도가 청소년의 성의식 및 태도에 어떠한 영향을 미치는지를 청소년 인권의식의 매개효과를 중심으로 검증하고자 하였다. 이를 위해 부산시중학생을 대상으로 설문조사를 실시하고, 최종 469명의 자료를 통계 분석하였다. 주요 연구결과를 살펴보면 첫째, 청소년의 인권의식은 주양육자의 수용적 양육태도와 청소년의 성의식 및 태도 관계에서 부분매개효과가 있는 것으로 나타났다. 둘째, 청소년의 인권의식은 주양육자의 자율적 양육태도와 청소년의 성의식 및 성태도 관계에서 부분매개효과가 있는 것으로 나타났다. 이와 같은 결과를 바탕으로 주양육자의 양육태도 개선과 인권의식 함양 위한 방안을 제시해 보고자 한다.