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      • KCI등재후보

        급성미로염으로 오인된 전정신경초종 1예

        한동열,장원익,이종대 대한평형의학회 2009 Research in Vestibular Science Vol.8 No.2

        Acute labyrinthitis is clinically characterized by cochlear symptom like sudden hearing loss, tinnitus and aural fullness and vestibular symptom like vertigo and spontaneous nystagmus. Several disease entities may mimic labyrinthitis when the disease does not manifest its own characteristic findings. We present the case of a 43-year-old female patient who was suffering from the acute vertigo and sudden hearing loss in her right ear. The speech discrimination score in right side was 24% and brain magnetic resonance imagine revealed a mass in internal auditory canal and minimally extending cerebellopontine angle. Removal of mass was performed via translabyrinthine approach and rapid vestibular compensation was accomplished after surgery. Acute labyrinthitis is clinically characterized by cochlear symptom like sudden hearing loss, tinnitus and aural fullness and vestibular symptom like vertigo and spontaneous nystagmus. Several disease entities may mimic labyrinthitis when the disease does not manifest its own characteristic findings. We present the case of a 43-year-old female patient who was suffering from the acute vertigo and sudden hearing loss in her right ear. The speech discrimination score in right side was 24% and brain magnetic resonance imagine revealed a mass in internal auditory canal and minimally extending cerebellopontine angle. Removal of mass was performed via translabyrinthine approach and rapid vestibular compensation was accomplished after surgery.

      • KCI등재

        금융마이데이터 서비스의 사용자 수용 결정요인에 대한 실증 연구 : UTAUT2 및 정보시스템성공모형을 중심으로

        한동열,김영준,김은석,김세진 한국생산성학회 2022 生産性論集 Vol.36 No.4

        In recent years, the data economy, which means a data-centric ecosystem, has proliferated and South Korea has been making efforts to activate the utilization of personal data in the financial field through the full-scale enforcement of the financial MyData industry. The purpose of this study is to understand the factors that influence the user’s intention to accept the financial MyData service. We designed the main research model using UTAUT2 and ISSM, which effectively analyse potential factors influencing user acceptance intentions. As a result of the analysis using 504 samples, performance expectancy, hedonic motivation, and price value positively affected Behavioral Intentions. Also, Information quality, service quality affected performance expectancy and effort expectancy. Finally, personal innovativeness had a positive impact on both hedonic motivation and price value. Theoretical and practical implications are also presented in the conclusion section. 최근 데이터 활용 생태계를 의미하는 데이터 경제가 확산되고 있으며, 정부는 금융마이데이터의 전면적인시행을 통해 개인의 금융데이터 활용 활성화를 위하여 많은 노력을 기울이고 있다. 본 연구의 목적은 금융마이데이터 서비스의 사용자 수용의도에 영향을 미치는 잠재요인을 분석하는 것이다. 이를 위해 사용자 수용의도 분석에 설명력이 높은 UTAUT2 모형과 ISSM 모형을 중심으로 연구모형을 구성하였다. 총 504개의 설문응답 샘플을 활용하여 분석한 결과, 성과기대 및 쾌락적 동기, 가격가치가 수용의도에 유의한 영향을 미치는것으로 나타났다. 또한, 정보품질 및 서비스품질은 성과기대와 노력기대에, 개인혁신성은 쾌락적 동기와 가격가치에 각각 유의한 영향을 미치는 것으로 나타났다. 최종적으로 학술적, 실무적 시사점과 한계점을 결론에제시하였다.

      • KCI등재

        술 중 부갑상선 호르몬 측정을 이용해 제거한 초과수 2차성 부갑상선 기능 항진증 1예

        한동열,김진국,이용화,이승원 대한이비인후과학회 2010 대한이비인후과학회지 두경부외과학 Vol.53 No.3

        The incidence of hyperparathyroidism has slowly increased recently with routine measurement of serum calcium and increasing awareness of the disease by the public. Despite the availability of expert surgeons and preoperative imaging investigations, some patients are re-operated for persistent or recurrent hyperparathyroidism. The main cause of re-operation is the presence of ectopic parathyroid gland or supernumerary parathyroid gland. Supernumerary parathyroid glands are more frequently described in the secondary hyperparathyroidism than in the primary hyperparathyroidism cases, especially in surgery for renal hyperparathytroidism. The intraoperative measurement of intact parathyroid hormone (iPTH) provides the surgeon with a quantitative test that predicts the postoperative serum calcium level and can justify early closure or further exploration for hyperfunctioning parathyroid gland. We present a case of parathyroidectomy of supernumerary parathyroid glands by monitoring intraoperative iPTH in patients with secondary hyperparathyroidism. Korean J Otorhinolaryngol-Head Neck Surg 2010;53:190-3

      • KCI등재

        Sublingual Immunotherapy in Asian Children: 2-Year Follow-Up Results

        한동열,박일호,신재민,유익원,조정선,이흥만 대한비과학회 2015 Journal of rhinology Vol.22 No.2

        Backgrounds: House-dust mites are the main cause of allergic rhinitis in Asia, for which immunotherapy (SLIT) is a currently accepted treatment. However, few studies have evaluated the efficiency of SLIT on Asian children with allergic rhinitis for a period longer than one year. The aim of this study was to investigate the efficacy and safety of SLIT for Asian children with allergic rhinitis due to house-dust mites over a 2-year period. Materials and Method: This study included 65 patients who had allergic rhinitis due to Dermatophagoides pteronyssinus and Dermatophagoides farinae. All patients were treated with SLIT (StaloralⓇ). Symptom scores and quality of life were evaluated by using questionnaires over two years. The medication score was assessed monthly by a diary medication card and serologic tests were evaluated before and two years after the start of treatment. Adverse effects and dropout rates were also investigated. Results: All nasal and non-nasal symptoms and quality of life were significantly improved after two years of treatment. Furthermore, the total medication score decreased significantly and the serologic tests showed a significant change two years after the start of SLIT. Although minor adverse effects were reported, no systemic reactions were observed. The dropout rate was 40%. Conclusion: SLIT is an efficient and safe therapeutic tool for a period of two years in Asian children with allergic rhinitis to house-dust mites.

      • 금융 마이데이터(MyData)서비스의 사용자 수용요인에 관한 연구 -ISSM모형 및 UTAUT2 모형을 중심으로

        한동열,김영준,김은석,이우영 한국경영학회 2022 한국경영학회 통합학술발표논문집 Vol.2022 No.8

        4차 산업혁명의 시대를 맞아 데이터의 중요성이 더욱 커지고 있으며, 국가적으로도 데이터 경제를 기반으로 한 디지털 혁신이 산업의 미래를 좌우하고 있다. 이런 상황에서 2022년 1월부터 정부는 금융분야의 마이데이터 서비스를 본격적으로 도입하였고, 금융기관 뿐만 아니라 핀테크, IT 등 수많은 기업들이 금융마이데이터 사업자 자격을 획득하여 본격적인 서비스 경쟁에 들어갔다. 금융마이데이터 서비스는 도입 초기 단계이므로 사용자들의 서비스 사용에 영향을 미치는 요인들을 체계적으로 규명하는 것은 시의적절한 연구라고 판단되나, 관련 연구는 미흡한 상황이다. 본 연구는 금융마이데이터 서비스의 사용자 수용의도에 영향을 미치는 요인들을 규명하는 것이며, 이를 위해 UTAUT2 및 정보시스템성공모형을 중심으로 연구모형을 설계하였다. 본 연구를 통해 금융마이데이터 관련 산업계 및 학계에 유의미한 시사점을 제공함으로써 데이터 산업 발전에 기여하고자 한다.

      • KCI등재후보

        Effect of Prostaglandin E2 on Vascular Endothelial Growth Factor Production in Nasal Polyp Fibroblasts

        한동열,조정선,문유미,이혜림,이흥만,이병돈,백병준 대한천식알레르기학회 2013 Allergy, Asthma & Immunology Research Vol.5 No.4

        Purpose: Angiogenesis is involved in the pathogenesis of chronic rhinosinusitis with nasal polyps. We aimed to investigate the effects of prostaglandinE2 (PGE2) on vascular endothelial growth factor (VEGF) production, the role of E-prostanoid (EP) 4 receptors, and the signal transduction pathwaymediating VEGF production in nasal polyp-derived fibroblasts (NPDFs). Methods: Eight primary NPDF cultures were established from nasalpolyps, which were incubated with or without PGE2. Reverse transcription-polymerase chain reaction amplification of EP receptors (EP1, EP2, EP3,and EP4) and immunofluorescence staining for VEGF production were performed. VEGF production via the cyclic adenosine monophosphate (cAMP)-dependent protein kinase A (PKA) and phosphatidylinositol 3-kinase (PI3K) pathways was evaluated by enzyme-linked immunosorbent assay. Results:All EP receptors were expressed in NPDFs. PGE2 significantly increased VEGF production concentration- and time dependently, and VEGFproduction was regulated by an EP4 receptor. Activation of intracellular cAMP regulated VEGF production. VEGF production was decreased by PKAand PI3K inhibitors via intracellular cAMP. Conclusions: PGE2 stimulates VEGF production via the EP4 receptor in NPDFs. These results indicatethat PGE2-induced VEGF production is mediated, at least partially, through cAMP-dependent signaling pathways. Therapies targeting the EP4 receptormay be effective in inhibiting the development of nasal polyps.

      • KCI등재

        도로 암반 절취사면에 대한 산 발생능력 평가의 사례연구

        민경원,한동열 한국자원공학회 2008 한국자원공학회지 Vol.45 No.2

        Acid rock drainage (ARD) developed as a result of road construction imposes various engineering, environmental, and social problems. Engineering impacts from ARD, the product of atmospheric oxidation of rock-forming sulfide minerals, including degradation of surface water quality, disintegration of construction materials, and structural damage of buildings, have been documented widely around the world. Evaluation of acid producing potential of earth materials is strongly suggested as an essential step in the pre-design stage of construction works especially in the vicinity of mining areas. To characterize the ARD and to evaluate acid producing potential of road-cut rocks, samples of rocks and water were collected from two road-cut sites of shale to phyllite showing such visual indicators of ARD as orange precipitates along streambed and rocks. Acid Base Accounting (ABA) and Net Acid Generation (NAG) test, the most commonly applied static test to evaluate the potential acidity, and X-ray diffraction (XRD) and X-ray Fluorescence (XRF) analysis were performed for fifteen rock samples. As a result, in terms of NAPP (Net Acid Producing Potential) and NAGpH (pH of Net Acid Generation), seven, four, and four rock samples were classified into a PAF (potentially acid forming) group, a NAF (non-acid forming) group, and an uncertain group, respectively. Water samples with low pH of 4.4, low dissolved oxygen (DO), and high contents of heavy metals and sulfate ion confirmed that the classification scheme by NAPP and NAGpH can be a reliable tool to assess acid producing potential of rock mass.

      • KCI등재

        중이 콜레스테롤 육아종의 임상 분석

        진희성,한동열,장원익,이인효,김이석,이병돈 대한이비인후과학회 2009 대한이비인후과학회지 두경부외과학 Vol.52 No.12

        Background and Objectives The Cholesterol granuloma is often observed in middle ear surgeries. In the clinic, it can be found in a normal ear, but also as a recurrent serous otitis media in non-responding medical therapy. The purpose of this study is to analyze the clinical characteristics of cholesterol granuloma with or without cholesteatoma. Subjects and Method We performed a retrospective study of 40 patients who underwent tympanomastoidectomy between January, 2000 and January, 2009 for cholesterol granuloma. We divided patients into a non-cholesteatoma group and a cholesteatoma group and observed the following clinical manifestations: initial symptom findings, ear drum findings, preoperative audiogram, postoperative audiogram, operative technique and operative findings. Results Cholesterol granuloma was found in 10.2% of 393 cases (40 cases) who underwent chronic otitis media surgery. Of these, 5.3% (21 cases) was diagnosed with non-cholesteatoma group and 4.8% (19 cases) was diagnosed in the cholesteatoma group. Chief complaints were the difficulty of hearing in the non-cholesteatoma group and otorrhea in the cholesteatoma group. Ear drums were nearly retracted and perforated in both groups, although the cholesteatoma group had more damaged ear drum. Distinctive features of hearing were the conductive type with a moderate degree and ossicular destruction showed missing or eroded incus. Major sites of cholesterol granuloma were antrum, air cells and epitympanum. Conclusion Although ear drum was relatively preserved in the non-cholesteatoma group of cholesterol granuloma, the hearing level and the degree of ossicular destruction were not so much different between the two groups. Therefore, a complete removal of cholesterol granuloma and ossiculoplasty should be considered for better hearing restoration.

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