Pathologic Differences between Placentas from Intrauterine Growth Restriction Pregnancies with and without Absent or Reversed End Diastolic Velocity of Umbilical Arteries

유창영,장동규,조윤성,유진영,이귀세라 대한병리학회 2011 Journal of Pathology and Translational Medicine Vol.45 No.1

Background: Abnormal umbilical artery Doppler velocimetry is one of the important findings of intrauterine growth restriction (IUGR) and IUGR is associated with high perinatal morbidity and mortality. In addition, this abnormal Doppler velocimetry is correlated with placental insufficiency. The aim of this study was to determine the pathologic differences in the placentas from IUGR pregnancies with and without the absent or reversed end diastolic velocity (AREDV). Methods: Among the cases that had undergone prenatal follow-up in our institute, a retrospective slide review was conducted for 18 cases of IUGR with AREDV and 17 cases with IUGR that had normal end-diastolic flow of the umbilical artery. Results: The birth weight and the other clinical parameters were not different among the two groups. Grossly, the placental weight percentiles were significantly smaller in AREDV group when they were adjusted according to gestational age. Histologically, chronic deciduitis, mural hypertrophy of the decidual arteries, an intimal fibrin cushion of the large fetal vessels, increased syncytial knots, villous agglutinations, avascular villi, villous stromal-vascular karyorrhexis, and acute atherosis were more frequently found in the AREDV group and their presence showed statistical significance. Conclusions: These findings suggest that pathologic abnormalities due to fetal and maternal vasculopathies in the placenta may be the cornerstone for inducing AREDV in the umbilical artery.

중간가공열처리한 Al-Li계 합금의 고온변형거동

유창영,진영철 ( C . Y . Yoo,Y . C . Jin ) 한국열처리공학회 1991 熱處理工學會誌 Vol.4 No.3

In this study, intermediate thermo-mechanical treated Al-2.0wt%Li, and Al-2.0wt%Li-1.2wt%Cu-1.0wt%Mg-0.12wt%Zr alloys were tested in tension at 10℃ and elevated temperature (100, 200 and 300℃). The results are follows : The tensile strength of Al-Li-Cu-Mg-Zr alloy is the highest but the elongation of Al-Li alloy is the highest(106%) among the all alloys in tension at 300℃. The Portervin-LeChartlier effect is showed in Al-Li-Cu-Mg-Zr alloy at 10 and 100℃, because of tangled dislocation by Mg and Cu. In the true stress-strain curves of all alloy, the peaks of stress at 300℃ are showed at the strain less than 0.1. In the binary alloy, the dynamic restoration process at 200 and 300℃ is nearly similar to dynamic recovery type. The hot deformation stress is decreased with increase of dynamic recovery degree, but the elongation is increased. When the strain the strain rate are constant, the temperature dependence of hot deformation stress is increased with increase of deformation temperature. The elongation and degree of dynamic recovery are decreased with increase of hot deformation activation energy, but the deformation stresses slightly increased.

과학관이야기 - 미리보는 '과천국립과학관'의 첨단기술관'(1)

유창영,Yu, Chang-Yeong 한국과학기술단체총연합회 2006 과학과 기술 Vol.39 No.11

갑상선에서 독립적으로 발생한 유두암종 및 수질암종- 3예 보고 -

유창영,김승남,이교영,김민식,정찬권,권혁상,김성헌 대한병리학회 2007 Journal of Pathology and Translational Medicine Vol.41 No.3

Although medullary thyroid carcinoma (MTC) may coexist with papillary thyroid carcinoma (PTC) as a collision tumor within the same nodule or as two or more spatially separated tumors, these two carcinomas rarely coexist. We encountered three cases of sporadic MTCs spatially separated from PTCs, which occurred concurrently, either within the same thyroid lobe or in different thyroid lobes. In each of the cases the patients underwent total thyroidectomy and neck dissection. PTC metastases of the lymph node were observed in two of the cases and MTC metastasis of the lymph node was observed in one case. Among the multiple thyroid nodules affected by both MTCs and PTCs, only the dominant nodules had spread to the lymph nodes. Because MTC has a different clinical significance from PTC, in patients with multiple thyroid nodules, appropriate diagnostic approaches, such as fine needle aspiration of all possible nodules and measurement of serum calcitonin level, should be performed.

Fine Needle Aspiration Cytology of Thyroid Follicular Neoplasm: Cytohistologic Correlation and Accuracy

유창영,최현주,임소영,정지한,민기옥,강창석,서영진 대한병리학회 2013 Journal of Pathology and Translational Medicine Vol.47 No.1

Background: This study evaluated the accuracy of fine needle aspiration cytology (FNAC) in cases of follicular neoplasm (FN) on the basis of histologic diagnosis, and reviewed the cytologic findings of FN according to the FNAC. Methods: Among the 66 cases diagnosed with thyroid FN by FNAC during the 7-year period from 2003 to 2009, 36 cases that had undergone thyroid surgery were available for review. Cytologic diagnosis was compared with the histologic diagnosis of each case. Results: Among the 36 cases with a cytologic diagnosis of thyroid FN, histologic diagnosis was as follows: 20 follicular adenomas (55.6%), 3 Hurthle cell adenomas (8.3%), 2 follicular carcinomas (5.6%), 8 nodular goiters (22.2%), 2 papillary carcinomas (5.6%), and 1 Hashimoto’s thyroiditis (2.8%), resulting in a diagnostic accuracy of FNAC for thyroid FN of 69.5%. Conclusions: This study shows that FNAC for thyroid FN is a useful primary screening method because when FN is diagnosed by FNAC, the rate of FN histologic diagnosis is relatively high, however, adequate sampling and experience is a prerequisite for this procedure.

중간가공열처리한 Al-Li계 합금의 인장성질에 미치는 용체화처리온도의 영향

유창영,이규복 ( C . Y . Yoo,K . B . Lee ) 한국열처리공학회 1991 熱處理工學會誌 Vol.4 No.1

In this study, the effect of solution treatment temperature on the tensile property in intermediate thermo-mechanical treated Al-Li alloys are investigated. After the intermediate thermo-mechanical treated Al-Li, Al-Li-Mg and Al-Li-Mg-Zr alloys were solution treated at various temperatures(500, 520 and 540℃), these were aged at 190℃, 240℃ and tested tensile properties. The results obtained from the experiment are as follows ; 1) The optimum solution heat-treatment temperature is 540℃ for a Al-Li alloy, and the recrystallized grain size is about 70㎛. 2) The optimum solution heat-treatment temperature is 500℃ for a Al-Li-Mg alloy, and the recrystallized grain size is the most coarse in all alloys. 3) The tensile property is independent of the solution treatment temperature in a Al-Li-Mg-Zr allay, and the recrystallized grain size is the finest owing to addition of Zr.

과학관이야기-미리보는 '과천국립과학관'의 첨단기술관'(2)

유창영,Yu, Chang-Yeong 한국과학기술단체총연합회 2006 과학과 기술 Vol.39 No.12

크론병에서 위 내시경 생검의 병리 소견

유창영,이보인,최규용,맹이소,이안희,강창석,권기영,김경미,박철근 대한병리학회 2006 Journal of Pathology and Translational Medicine Vol.40 No.4

Background : The incidence of Crohn’s disease in the upper digestive tract, and especially in the stomach, is recently increasing. Focal inflammatory reaction without Helicobacter pylori (H. pylori) infection is thought to be the characteristic pathologic findings suggesting Crohn’s disease in the stomach. Yet gastric involvement of Crohn’s disease has not been studied in Korea. We studied the endoscopic and pathologic findings of patients with Crohn’s disease in the stomach by taking biopsies. Methods : Thirty patients with Crohn’s disease who underwent gastroduodenoscopy followed by biopsies were included in the study. The pathology of the gastric biopsy specimens and the presence of H. pylori were evaluated. Results : Among 30 cases, 22 cases (73.3%) were H. pylori negative and 8 cases (26.7%) were H. pylori positive. For the H. pylori negative cases, all but one cases showed pit abscess and focal lymphocytic collections in the antrum. Granulomas were found in 6 cases (20%) and they were exclusively located in the antrum. Conclusions : In the stomach, pit abscess and focal lymphocytic collections that are not associated with H. pylori infection are the characteristic pathologic findings found in Crohn’s disease.

도시환경요인과 범죄정책인식의 관계연구

유창영,권준성,최주희 사단법인 한국안전문화학회 2022 안전문화연구 Vol.- No.16

The purpose of this study is to empirically explore the effect of urban environmental factors on criminal policy through crime fear and crime prevention activities. In addition, it was confirmed that crime fear and crime prevention activities are closely related to the characteristics and structure of the city, and are deeply related to criminal policy and satisfaction with life in urban areas. As a result of the study, it was found that urban environmental variables were not related to crime prevention activities, did not directly affect crime policy perception, and had an indirect effect on crime policy perception by completely mediating crime fear. Contrary to expectations, crime prevention activities did not have the effect of mediating urban environmental variables and criminal policy perception, and it was found that they served as independent variables that influence criminal policy perception by completely mediating criminal fear. Through this, it was confirmed that environmental variables such as urban environment and behavioral variables such as crime prevention activities are likely to affect recognition factors such as crime suppression policy satisfaction through psychological variables.

Merkel 세포 암종의 동결절편진단에 있어 접착도말의 유용성 -1예 보고-

유창영,이연수,박주완,강창석,심상인,이교영,박경신,Yoo, Chang-Young,Lee, Youn-Soo,Park, Joo-Wan,Chang, Suk-Kang,Shim, Sang-In,Lee, Kyo-Young,Park, Gyeong-Sin 대한세포병리학회 2006 대한세포병리학회지 Vol.17 No.2

Merkel cell carcinoma (MCC), a rare primary cutaneous small cell neuroendocrine carcinoma, is a tumor with distinct cytological features. In many cases, immunohistochemical staining (IHC) is required for the differentiation from other small round cell malignancies. Here we describe the cytological findings of Merkel cell carcinoma; these findings contributed to the diagnosis prior to performing IHC. A lower eyelid mass was excised and submitted for frozen section diagnosis. The frozen section diagnosis was consistent with a malignancy, but the more specific diagnosis was limited by the lack of specific histological features. Touch imprint cytology revealed a high cellularity with loosely cohesive small to large sized cells. The tumor cells showed hyperchromatic nuclei with fine chromatin and inconspicuous nucleoli, and thin-rimmed-cytoplasm including the characteristic eosinophilic button-like paranuclear inclusion, previously described as a pathognomonic cytological finding of MCC; this was not found in the H&E frozen section. In conclusion, we suggest that the touch imprint cytology may help in the differential diagnosis of small round cell neoplasms prior to performing IHC especially in frozen section diagnosis.