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Utilization of multivalent vaccine on sows ante partum for the prevention of piglet enteritis
오연수,김명희,한정희 한국동물위생학회 2017 韓國家畜衛生學會誌 Vol.40 No.2
Three swine farms which were suffering from slight economic loss due to suckling piglets’ diarrhea, were selected to apply commercialized multivalent vaccine for sow use; SUISENGⓇ (Hipra, Spain). Farms were pre-diagnosed with clinical symptoms and molecular detection of C. perfringens Type A and C and E. coli pili by PCR. Sows were vaccinated twice 2 ml of the vaccine at 6 and 3 weeks ante partum intramuscularly according to the manufacturer’s instruction. All vaccinated sows did not show any adverse reaction or clinical signs; hypersensitivity, fever, granuloma or abscess on the in-jection site, appetite loss, and so on. Also, no reproductive disorder was appeared in vaccinated sows compared with non-vaccinated control sows. The results suggested that piglets born from vaccinated sows show significantly better performance in regard of the diarrhea index and mean daily weight gain compared with piglets from non-vaccinated sows. Therefore, the commercial vaccine for the prevention of neonatal diarrhea is found to be effective in reducing diarrhea in the first suckling period of piglets after birth.
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Primary pulmonary adenocarcinoma metastasized to kidney in a captive nutria (Myocastor coypus)
오연수,조호성 한국동물위생학회 2017 韓國家畜衛生學會誌 Vol.40 No.2
A six-year-old male captive nutria (Myocastor coypus) maintained in a closed space with a small vent was found dead in his cage. Gross findings showed multifocal nodules in varying sizes, small 0.5 to large 5 cm in diameter, intermixed with normal parenchyma were scattered all over the surface of the lungs and a kidney, which the cut surface was smooth, compact and whitish in color. Microscopically, small round to oval neoplastic cells with modest to slight amounts of cytoplasm formed acinar and gland-like structures. Immunohistochemically, cells were strongly positive for E-cadherin and slightly re-active for thyroid transcription factor-1 (TTF-1). Based on those diagnostic features, the neoplasia was diagnosed as primary pulmonary adenocarcinoma (small cell type) and metastasized into the kidney. This is the first case report of malignant pulmonary tumor and its metastasis in the nutria.
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오연수,유경빈 한독교육학회 2019 한독교육학회 학술대회 자료집 Vol.2019 No.2
본 연구는 ADHD 아동을 양육하는 어머니들의 경험을 구체적이고 심층적으로 탐색하여 양육경험의 큰 틀을 살펴보고 ADHD 아동관련 중재방안 및 통합적이고 절충적인 방법을 제안하는데 목적이 있다. 연구 참여자는 12명의 ADHD 어머니를 대상으로 반 구조화된 질문지로 2~3회 심층면접을 통해 자료 수집하였다. 자료 분석은 어머니들의 양육과정에서 드러나는 상황들이 다수 또는 소수의 사례임을 짐작할 수 있는 합의적 질적 연구방법(Consensual Qualitative Research : CQR)을 활용하여 영역들과 범주들을 도출하였다. CQR을 통해 ADHD 어머니들의 다양한 경험들을 심도 있게 분석하였으며 합의 과정을 통해 사례들을 종합하여 수치화하여 전체적인 패턴과 특수성을 파악하였다. 그 결과 11개의 영역들과 51개의 범주들이 도출되었다. 11개의 영역들은 ‘ADHD 증상에 대한 무지’, ‘ADHD 진단 마주하기’, ‘ADHD 진단 후 주변 반응’, ‘ADHD 진단 수용’, ‘약물치료에 대한 양가감정’, ‘ADHD 진단 후 양육 감정’, ‘ADHD 적극적 치료 개입’, ‘가족의지지’, ‘사회적지지’, ‘사회적 인식변화’, ‘성숙한 부모’로 나타났다. 이를 통해 ADHD 아동에 대한 조기의 치료 및 개입이 중요하며 ADHD 진단 수용 및 부모교육을 통한 정확한 이해를 바탕으로 적절한 중재가 ADHD 자녀와 어머니의 삶을 긍정적으로 이끌 수 있다는 점을 시사한다. 마지막으로 이를 근거로 추후 연구를 위한 제언을 하였다. The purpose of this study is to explore the meaning of the essence through the parenting experience of the mother with ADHD children. Also, their parenting experiences were divided into domains and categories. The data was collected through several in-depth interviews with 12 semi-structured questionnaires of the mother with ADHD children. The analysis of the data has adopted a consensus qualitative research method(CQR), also known as CQR, to assume whether the phenomenon of mother’s experience with ADHD children was the majority’s or the minority’s experiences. Through CQR, various experiences of ADHD mothers were deeply analyzed. By consensus processes, the cases weree synthesizes and digitized comprehend overall patterns and distinct characteristics. As a result, 11 domains and 51 categories were derived. The 11 domains were classified as ‘Ignorance of ADHD symptom’, ‘Confronting ADHD diagnosis’, ‘Peripheral reaction after ADHD diagnosis’, ‘Acceptance of ADHD diagnosis’, ‘Ambivalence for medication’, ‘ADHD active treatment intervention’, ‘Family support’, ‘Social support’, ‘Social perception change’, and ‘Mature parent’. This suggests that early treatment and intervention for ADHD child is significant. Also, appropriate intervention is required based on accurate understanding through acceptance of ADHD diagnosis and that parent education can lead to positive life for the mother and the children and with ADHD. Lastly, suggestions for future research are provided based on this research.
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Establishment of hydrochloric acid/lipopolysaccharide-induced pelvic inflammatory disease model
오연수,이재훈,김현철,한태욱,윤병일,한정희,권용수,Joung-Jun Park,구덕본,이기종,정배동 대한수의학회 2016 Journal of Veterinary Science Vol.17 No.3
Pelvic inflammatory disease (PID), which is one of the most problematic complications experienced by women with sexually transmitted diseases, frequently causes secondary infections after reproductive abnormalities in veterinary animals. Although the uterus is self-protective, it becomes fragile during periods or pregnancy. To investigate PID, bacteria or lipopolysaccharide (LPS) extracted from gram negative bacteria has been used to induce the disease in several animal models. However, when LPS is applied to the peritoneum, it often causes systemic sepsis leading to death and the PID was not consistently demonstrated. Hydrochloric acid (HCl) has been used to induce inflammation in the lungs and stomach but not tested for reproductive organs. In this study, we developed a PID model in mice by HCl and LPS sequential intracervical (i.c.) administration. The proinflammatory cytokines, interleukin (IL)-1b, IL-6 and tumor necrosis factor-a, were detected in the mouse uterus by western blot analysis and cytokine enzyme-linked immunosorbent assay after HCl (25 mg/kg) administration i.c. followed by four LPS (50 mg/kg) treatments. Moreover, mice exhibited increased infiltration of neutrophils in the endometrium and epithelial layer. These results suggest that ic co-administration of HCl and LPS induces PID in mice. This new model may provide a consistent and reproducible PID model for future research.
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