보건소 금연클리닉 6개월 금연성공자의 재흡연과 관련요인

손효경,정운영,박기수,감신,박선균,이원기,Son, Hyo-Kyung,Jung, Un-Young,Park, Ki-Soo,Kam, Sin,Park, Sun-Kyun,Lee, Won-Kee 대한예방의학회 2009 예방의학회지 Vol.42 No.1

Objectives : This study was conducted to examine the factors implicated when people start smoking again after a 6 month cessation, and was carried out at the smoking cessation clinic of a public health center. Methods : The study subjects were 191 males who had attended the smoking cessation clinic of a public health center for 6 months in an attempt to quit smoking. Data was collected, by phone interview, regarding individual smoking habits, if any, over the 6 month study period. The factors which may have caused an individual to smoke again were examined. This study employed a health belief model as it theoretical basis. Results : Following a 6 month cessation, 24.1% of the study group began to smoke again during the 6 month test period. In a simple analysis, the factors related to individuals relapsing and smoking again included barriers of stress reduction, body weight gain and induction of smoking by surroundings among perceived barriers factor of our health belief model(p<0.05). In multiple logistic regression analysis for relapsed smoking, significant factors included barriers of stress reduction and induction of smoking by surroundings(p<0.05). The most important reason of for an individual to relapse into smoking was stress(60.9%) and the most likely place for a relapse to occur was a drinking establishment(39.1%). Conclusions : Our results indicate that both regular consultations and a follow-up management program are important considerations in a public health center program geared towards maintaining smoking cessation.

유방암 조기검진에 대한 단계별 행동과 관련 요인 -국가암조기검진 대상자를 중심으로-

손효경,감신,박기수,김장락,김록범,박선균,Son, Hyo-Kyung,Kam, Sin,Park, Ki-Soo,Kim, Jang-Rak,Kim, Rock-Bum,Park, Sun-Kyun 대한예방의학회 2009 예방의학회지 Vol.42 No.2

Objectives : This study was performed to evaluate the relationships between psychosocial characteristics and changes in the stage of breast cancer screening behavior. Methods : The 474 study subjects were randomly sampled from 21,459 women(age range, 40-70 years) who were eligible for the Korean National Cancer Screening Program in 2006 in Jinju, Gyeongsangnam-do. The information, including behaviors and sociodemographic characteristics, attitudes, subjective norms and self-efficacy, was collected by trained interviewers via home visits. The breast cancer screening stages were grouped as precontemplation, contemplation, action, maintenance and relapse, according to Rakowski. Results : Of the 474 women, 18.8% were in the precontemplation stage, 23.3% were in the contemplation stage, 13.1% were in the action stage, 36.6% were in the maintenance stage, and 8.2% were in the relapse stage. The distribution of stages was associated with attitude, subjective norms and self-efficacy(p for trend<0.01). To investigate the overall relationship between the variables, we conducted a linear structural equation model analysis based on the theory of planned behavior. The subjective norms and self-efficacy influenced the stage of the women's screening behavior. Conclusions : We should target on self-efficacy about the screening behavior of women by performing timely, thoughtful interventions. The support from family members, friends and other people is crucial for women to undergo breast cancer screening and to improve the breast cancer screening rate.

섬망 환자에서 Amisulpride의 유효성 및 내약성에 관한 예비 연구

손효경(Hyo Kyong Son),이종훈(Jong Hun Lee),최태영(Tae Young Choi),강승걸(Seung-Gul Kang),박종한(Jonghan Park),원승희(Seunghee Won) 대한생물치료정신의학회 2011 생물치료정신의학 Vol.17 No.1

Objectives : Delirium is a disorder that needs active treatments since it is associated with poor outcomes such as comorbidity, longer hospital stay, higher mortality rate, higher rates of institutional care and dementia. This study was done to investigate the efficacy and safety of amisulpride, a atypical antipsychotic drug that is in possession of distinguishable pharmacodynamic profile characteristics from other widely used atypical antipsychotic drugs, but it has characteristics that are most similar to haloperidol which was the most commonly used antipsychotic drug treating patients with delirium in a safe manner. Methods : We recruited 19 delirium patients. Korean version of Delirium Rating Scale-Revised-98(K-DRS-R-98) and Korean version of Delirium Rating Scale(K-DRS) had been used to measure severity and improvement of delirium symptoms. Clinical Global Impression Severity Score(CGI-S) had been used to examine general medical conditions in the patients. The assessment on side effects began from day 2 for every visit to patients using Simpson-Angus Scale(SAS), Barnes Akathisia Rating Scale(BARS), Abnormal Involuntary Movement Scale(AIMS). Results : A total of 14 patients completed the study. They were administered with mean amisulpride dose 86.16 (SD=39.01) ㎎ per day. The K-DRS scores were decreased from 21.57±4.72 before the treatment to 7.14±0.84 after the treatment(p<0.01). The K-DRS-R-98 scores also were significantly decreased from 25.07±6.40 before the treatment to 9.93±1.09 after the treatment(p<0.01). Among detailed K-DRS-R-98 scale items, the sleep item also showed a significant decrease(p<0.01). There was no patient who suffered serious side effects. In 35.7% of the patients, the mild rigidity and mild tremor of extrapyramidal symptoms occurred. Conclusion : Amisulpride is expected to be used effectively and safely in treating delirium patients.

MSS공법으로 시공되는 교량의 시공단계별 시간의존적 거동

곽효경(Kwak Hyo-Gyoung),손제국(Son Je-Kuk) 대한토목학회 2004 대한토목학회논문집 A Vol.24 No.4A

교정장치를 부착한 환자에서 표준진료지침의 구강위생관리능력 개선효과

손우성 ( Woo Sung Son ),김용일 ( Yong Il Kim ),송효경 ( Hyo Kyung Song ),김진범 ( Jin Bom Kim ) 대한예방치과·구강보건학회 2010 大韓口腔保健學會誌 Vol.34 No.2

Objectives. The purpose of this study is to evaluate the effect of the oral hygiene education using the newly designed clinical pathway improving the oral hygiene capability of patients with fixed orthodontic appliance to manage oral hygiene. Methods. The study was conducted on patients beginning orthodontic therapy with fixed orthodontic appliance in Department of Orthodontics, P University Hospital. We applied the newly designed critical pathway on test group (each twenty male/female patients in their teens and twenties) and regular oral hygiene education on control group (each twenty male/female patients in their teens and twenties) and evaluated their capability of oral hygiene management by plaque index and gingival bleeding index. We also evaluated it by age, gender, and period of attaching orthodontic appliance. Independnet t-test and ANOVA were used for statistical analysis. Results. The plaque indices of the test group were lower than those of the control group one, two, three month after bonding the brackets. There were no significant differences in the gingival bleeding indices between test and control group one, two, three month after bonding the brackets. At one month after bonding the brackets, the plaque indices decreased greatly, but 3 months later, the plaque indices became similar to those before orthodontic treatment. Conclusions. Education of oral hygiene management with critical pathway is more effective than the traditional method for the reduction of dental plaque. Education is necessary every 3 months to maintain the oral hygiene abilities continuously.

FCM공법으로 시공되는 교량의 켄틸레버 텐던 모멘트

곽효경(Kwak Hyo-Gyoung),손제국(Son Je-Kuk) 대한토목학회 2002 대한토목학회논문집 A Vol.22 No.3A

MSS공법으로 시공되는 교량의 설계 모멘트 결정

곽효경,손제국 한국전산구조공학회 2001 한국전산구조공학회논문집 Vol.14 No.3

이 논문에서는 이동식 지보를 이용한 MSS공법에 의해 건설되는 콘크리트 교량의 설계 모멘트를 산정하기 위한 관계식을 제안하고 있다. 각 시공 단계에 따른 시간 의존적 거동해석을 통해 교량의 부재력 변화와 처짐 변화를 고찰하였으며 변위와 하중조건을 토대로 한 지배방정식을 구성한 후 복잡한 장기 거동 해석 없이 탄성 해석 결과를 토대로 설계 부재력과 임의의 시간 경과 후 모멘트 변화를 예측할 수 있는 관계식을 구성하였다. 나아가 다양한 예제 해석을 통해 제안한 관계식의 적용성을 검증하였으며 모멘트 포락선을 토대로 보다 합리석인 설계 부재력의 산정 방안을 소개하였다. In this paper, a relation to calculate design moments for reinforced concrete(RC) bridges constructed by movable scaffolding system(MSS) is introduced. Through the time-dependent analysis of RC bridges considering the construction sequence, the structural responses related to the member forces and deflections are reviewed, and a governing equation for determination of the design moment, which includes the creep deformation, is derived on the basis of the displacement-force condition at every constructuion stage. By using the relation, the design moment and its variation over time can easily be obtained only with the elastic analysis results without additional time-dependent analysis. In addition, correlation studies with the results by rigorous numerical analyses are conducts to verify the applicability of the introduced relation, and a more reasonable guideline for the determination of design moments is proposed on the basis of the obtained moment envelop.

Synthesis and Structure–Activity Relationship of Novel Indole Acrylamide Derivatives as HCV Replication Inhibitors

손서현,김다희,이성진,Guanghai Jin,박진아,한효경,이경,이충호 대한화학회 2015 Bulletin of the Korean Chemical Society Vol.36 No.1

A series of indole acrylamide derivatives were synthesized and evaluated for their inhibitory effects on hepatitis C virus (HCV) replication. Previously, we have identified (E)-N-(4-tert-butylphenyl)-3-(5-cyano-1H-indol-3-yl)-2-methylacrylamide (6c) as one of the promising leads for anti-HCV chemotherapy. Based on the structural features of indole acrylamide, we have explored extended structure

Cone beam CT 영상과 석고모형 레이저 스캔 영상의 결합을 이용한 안면비대칭자의 치성보상 평가

송효경(Hyo-Kyung Song),손우성(Woo-Sung Son),박수병(Soo-Byung Park),김성식(Seong-Sik Kim),김용일(Yong-Il Kim) 대한치과교정학회 2010 대한치과교정학회지 Vol.40 No.6

본 연구에서는 CBCT 영상과 석고모형 레이저 스캔 영상의 결합하여 안면비대칭자의 치성보상을 3차원적으로 계측하고 비교하였다. 안면비대칭자 30명과 정상교합자 20명을 대상으로 하여, CBCT 영상에서 두개악안면 골격에 대한 기준 좌표계를 설정하고 석고모형 레이저 스캔 영상에서 견치와 제1대구치의 3차원적 위치와 각도를 계측하여 그 차이(dev.-ndev.)를 구하였다. 두 집단을 비교 분석하고 이부 편위량과의 상관 분석을 시행하여 다음과 같은 결과를 얻었다. 안면비대칭군의 편위측 상악 견치는 비편위측에 비해 2.73 ± 4.07 mm 협측에 위치하였고, 편위측 상악 제1대구치는 비편위측에 비해 3.83 ± 0.12 mm 협측에 위치하였으며, 8.26 ± 6.82˚ 협측 경사되어 있었다. 비편위측 상악 제1대구치의 협측교두는 편위측에 비해 1.76 ± 0.11 mm 정출되어 있었다. 편위측 하악 제1대구치는 비편위측에 비해 6.01 ± 0.14 mm 설측에 위치하였고, 비편위측에 비해 8.31 ± 7.07˚ 설측경사되어 있었다 (p < 0.01). 안면비대칭자는 이부 편위량이 증가할수록 상악 제1대구치는 비편위측에 비해 편위측에서 협측 경사가 증가하는 양상을 보였고, 하악 제1대구치는 편위측에서 설측 경사가 증가하는 양상을 보였다. 또한 상악 제1대구치의 모든 교두와 하악 제1대구치의 근심설측 교두의 수직적 위치는 비편위측에서 더 정출되는 경향을 보이며, 하악 견치와 제1대구치의 횡적 위치도 편위측에서 좀 더 설측으로 위치하는 양상을 보였다. 이상의 결과에서 안면비대칭군에서 편위측의 견치와 대구치가 비편위측에 비해 횡적으로 기울어져 있고, 수직적 위치 및 각도의 차이를 보임을 확인하였다. (대치교정지 2010;40(6):373-382) Objective: The purpose of this study was to assess the dentoalveolar compensation in facial asymmetry individuals using an integration of a CBCT image and a laser scanned dental cast image. Methods: The subjects consisted of 30 adults with asymmetric mandibles and 20 adults with symmetric mandibles. The CBCT and laser scanned dental cast images were integrated with a registration technique. Canine and first molar position and angulation were assessed from reference coordinates. The differences between deviated and non-deviated sides were analyzed with the paired t-test. The differences shown according to menton deviation were also statistically analyzed using Pearson correlation analysis. Results: The experimental group showed deviated and non-deviated side differences (dev.-ndev.) in the position and angle of the canine and first molars. Menton deviation showed positive correlation with the deviation side (dev.-ndev.) for the maxillary and mandibular 1st molar angles, negative correlation with the deviation side for the vertical position of the maxillary 1st molars, transverse position of the mandibular canine, transverse position and vertical position of the mesio-lingual cusp of the mandibular 1st molars. Conclusions: The upper and lower canine and first molars of facial asymmetry individuals were compensated, so the transverse position, vertical position, and angle showed differences between the deviated/ non-deviated sides. (Korean J Orthod 2010;40(6):373-382)

건조농산물의 잔류농약 안전성 조사

이효경,오문석,정진아,김기유,이성봉,김한택,강향리,손지희,이윤미,이미경,이병훈,김지원,박용배 한국식품위생안전성학회 2019 한국식품위생안전성학회지 Vol.34 No.4

We performed a safety survey on residual pesticides in dried agricultural products. A total of 110 samples of dried agricultural products distributed in Gyeonggi-do were analyzed for 263 pesticides according to multi class pesiticide multiresidue method. Ten types of pesticides were detected in 10 samples. Chlorpyrifos was detected in Ricinus communis leaves, chlorpyrifos, hexaconazole, pyridalyl in Chwinamul (wild aster), diniconazole, isoprothiolane, lufenuron in radish leaves, hexaconazole in Cirsium setidens (Korean thistle), bifenthrin, and chlorothalonil, boscalid, and pyraclostrobin in pepper leaves. The detection rate of pesticides was 9.1%, and among these samples, one was detected over Maximum Residue Limits (MRLs). In the validation study, the values of limit of detection (LOD), limit of quantitation (LOQ), coefficient of determination (R 2 ) and recovery were in the range of 0.002~0.027 mg/kg, 0.006~0.083 mg/kg, 0.9964~1.0000 and 74.8~118.9%, respectively. The Positive List System (PLS) was newly introduced as part of the safety management of residual pesticide in agricultural products in Korea in 2019. With the application of the PLS, if the MRL is not established, 0.01 mg/kg limit is applied uniformly. In spite, these of strengthened residue limits, the MRLs of dried agricultural products are still insufficient. Therefore, this study could be utilized as basic data for the setting of proper MRLs.