만성 신부전 환자에서 발생한 Verapamil 독성 4예

박진아,신미정,형복진,박훈석,윤정민,최범순,양철우,김용수,김석영,방병기 대한신장학회 2005 Kidney Research and Clinical Practice Vol.24 No.3

Four hypertensive patients with chronic renal insufficiency who were treated with sustained release verapamil hydrochloride subsequently developed acute toxic effects. All four patients developed marked bradycardia, hypotension, hyperkalemia and metabolic aciodosis and were treated with atropine, fluid therapy, potasium lowing measure, dialysis, and temporary pacemaker, and were restored to the renal function and sinus rhythm after 12-24 hr. Patients with renal impairement who are treated with sustained release verapamil may accumulate verapamil or its metabolites and develop toxic side effects. We conclude that sustained release verapamil should be used with caution in chronic renal failure and that patients should be closely monitored for adverse cardiovascular, metaboic, and hepatic side effects. (Korean J Nephrol 2005;24(3):501-509) Verapamil은 주로 심근과 혈관의 평활근에 작용하여 세포막에 있는 칼슘 통로 (calcium channel)를 차단하여 심근의 부하를 줄이고 말초동맥과 관상동맥을 확장시키는 작용을 가지고 있어서 협심증, 상심실성 빈맥, 고혈압 등 심혈관계 질환과 편두통 질환의 치료에 이용되고 있다1). 또한 만성 신부전 환자에서 단백뇨 감소 및 신기능 보호효과가 있어 널리 쓰이고 있다2). Verapamil의 독성은 완전 방실 전도 차단을 비롯한 심부정맥과 말초 혈관 저항의 감소 및 심근 수축력의 저하로 인한 저혈압이 대표적이고, 간독성과 고혈당, 고칼륨혈증과 경련, 오심, 구토 및 폐부종이 알려져 있다4). 지금까지 Verapmil의 독성에 대한 보고는 거의 없으며, 대부분은 과량 복용에 의한 것이었다3). 외국에는 만성 신부전 환자에서 치료 용량의 verapamil 사용 후 발생한 독성을 보고한 예가 있으나2,5), 국내에서는 자살 목적으로 과량 복용한 verapamil 중독을 보고한 증례 이외에1) 치료 용량의 verapamil을 사용하고 발생한 부작용을 발표한 증례는 없었다. 저자들은 고혈압과 단백뇨를 보이는 만성 신부전 환자에서 서방정 verapamil을 치료용량으로 사용 후 혈압 강하, 대사성산증, 고칼륨혈증과 부정맥이 발생하였으며 투약중지 후 증세가 호전된 4예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

경남 기계설계산업 근무복 착용실태에 관한 연구 -소재와 형태에 따른 동작적합성 만족도를 중심으로

박진아,박혜원,배현숙 한국의류학회 2007 한국의류학회 학술대회논문집 Vol.2007 No.1

잠재적 휴업과 실패의 사정 - 이상, 「휴업과 사정」을 중심으로

박진아 한국문학이론과비평학회 2013 한국문학이론과 비평 Vol.60 No.-

Lee Sang is a writer who captured contradiction and anxiety inherent in the colonial modern society more sensitively than any other contemporary author. His works have significance in that they expressed a modern conflicting mechanism by unintelligible methods and showed its basical problem clearly. So, many studies have been conducted on works of Lee Sang. However, existing studies have focused mainly on several central ones among his works. Accordingly, especially in case of his early novels,Therefore this study intends to concentrate on his early work 「A Shutdown &Reasons」, particularly in works of Lee Sang. Especially, this treatise raises a question on the existing conclusion that this work is a 'conflict between the premodern and the modern' and identifies this work is the one revealing ambivalent aspects of the modern age through a frame of a love triangle. Modern love story having an eternal triangle is the genre of novels that shed light on those days centered on the relationship invented in the modern period. Through such a frame of the love triangle, 「A Shutdown & Reasons」by Lee Sang also shows a process making 'I' as a modern while 3 characters in charge of each axis of the love triangle create their inner side through others. At the same time, it shows a fundamental contradiction of the concept of 'Na' through failure of the intellectual character, Bosan. Lee Sang's recognition of the modern shown from 「A Shutdown & Reasons」has a connecting point with reading of his other later works. Therefore, a new meaning of 「A Shutdown & Reasons」this study examined will lead to a possibility of a new critique on the entire work world of Lee Sang. 이상은 식민지 근대사회의 모순과 그 안에 내재된 불안을 동시대의 다른 작가들보다도 민감하게 포착한 작가이다. 그의 작품들은 근대가 가진 모순적인 매커니즘을 난해한 표현방식을 통해 표현함으로써 오히려 그것이 가진 근본적인 문제점을 선명하게 드러내었다는 점에서 의의를 가지고 있으며, 이로 인해 그동안 이상의 직품에 대한 많은 연구가 진행되어 왔다. 그러나 기존의 연구들은 이상의 작품들 중에서도 몇몇 중심적인 작품들만을 중점적으로 연구하였던 성격이 강하였으며 이로 인해 특히 이상의 초기 소설들의 경우에는 그의 작품세계의 기반이 되는작품들임에도 불구하고 제대로 연구되지 못한 측면이 많았다. 이에 본고는 이상의 작품 중 초기작인 「휴업과 사정」에 주목하고자 한다. 본고는 이 작품에 대한 기존의 '전근대와 근대간의 갈등'이라는 결론에 의문을 제기하고 삼각관계 구도를 통해 인물들이 근대인으로서의 내면을 만들어가는 과정을 살펴보고자 한다. 이상의 「휴업과 사정」 은 삼각관계의 각 축을 담당하는 세 인물이타자를 통해 자신의 내면을 만들어가며 근대인으로서의 '나'가 만들어지는 과정을보여줌과 동시에 보산이라는 지식인 인물의 패배를 통해서 '나'라는 개념이 가진근본적인 모순을 드러내고 있다. 「휴업과 사정」에 드러난 이상의 근대인식은 이후 이어지는 그의 다른 작품들을독해와 연결지점을 가지고 있으며, 따라서 본고에서 밝힐 「휴업과 사정」이 가진새로운 의의는 이상의 작품세계 전체에 대한 새로운 비평의 가능성으로 이어질 수있을 것이다.

[정책제안] 중증정신질환자 위한 지역사회 치료체계 강화해야

박진아 한국주민자치학회 2024 월간 공공정책 Vol.219 No.-

정부제출법안 입법생산성의 영향 요인 분석: 규제 관련 법안을 중심으로

박진아 한국행정학회 2016 한국행정학회 학술발표논문집 Vol.2016 No.동계

종합병원 간호사의 비판적 사고성향과 임상수행능력

박진아,김복자 한국간호과학회 2009 Journal of Korean Academy of Nursing Vol.39 No.6

Purpose: This study was done to investigate the relationship between critical thinking disposition and clinical competence among nurses in general hospitals. Methods: This study was a descriptive-correlational study with a convenience sample of 560 nurses from 5 general hospitals. The data were collected by self-administered questionnaires. Critical thinking disposition was measured using the Critical Thinking Disposition Scale for Nursing Students. Clinical competence was measured using the Standardized Nurse Performance Appraisal Tool. Results: The mean score for critical thinking disposition and clinical competence was 3.37 and 4.10 respectively on a 5 point scale. A statistically significant correlation was found between critical thinking disposition and clinical competence. A regression model explained 72.8% of clinical competence. Prudence is the most significant predictor of clinical competence (R2=.728). Conclusion: Study findings suggest that nurses with a higher level of critical thinking disposition would have a higher level of clinical competence. Furthermore, prudence might be the most important predictor of clinical competence. In order to strengthen clinical competence in nurses, the development and enhancement of critical thinking should be emphasized at the college level and nurses should be encouraged to make a clinical decision with greater prudence. Purpose: This study was done to investigate the relationship between critical thinking disposition and clinical competence among nurses in general hospitals. Methods: This study was a descriptive-correlational study with a convenience sample of 560 nurses from 5 general hospitals. The data were collected by self-administered questionnaires. Critical thinking disposition was measured using the Critical Thinking Disposition Scale for Nursing Students. Clinical competence was measured using the Standardized Nurse Performance Appraisal Tool. Results: The mean score for critical thinking disposition and clinical competence was 3.37 and 4.10 respectively on a 5 point scale. A statistically significant correlation was found between critical thinking disposition and clinical competence. A regression model explained 72.8% of clinical competence. Prudence is the most significant predictor of clinical competence (R2=.728). Conclusion: Study findings suggest that nurses with a higher level of critical thinking disposition would have a higher level of clinical competence. Furthermore, prudence might be the most important predictor of clinical competence. In order to strengthen clinical competence in nurses, the development and enhancement of critical thinking should be emphasized at the college level and nurses should be encouraged to make a clinical decision with greater prudence.

조선 산업 작업공정별 작업복 및 보호복 의복구성적 분석

박진아,박혜원,배현숙 한국의류학회 2009 한국의류학회 학술대회논문집 Vol.2009 No.1

과학기술인의 사회적 위상 - 과학기술인에 대한 예우 및 지원 입법 방안

박진아,Park, Jin-A 한국과학기술단체총연합회 2013 과학과 기술 Vol.531 No.-

JFMA Forum 참관 일본 기술 동향 보고

박진아 한국퍼실리티매니지먼트학회 2017 한국퍼실리티매니지먼트학회지 Vol.12 No.1

진주지역 실크제조업체 스마트 팩토리 준비도 진단 사례조사

박진아,임지영 한국문화융합학회 2023 문화와 융합 Vol.45 No.12

The study aimed to assess the smart factory readiness of small and medium-sized silk textile manufacturers to introduce and advance the smart factory strategies. A comprehensive questionnaire with a 5-point scale was used to evaluate various aspects of resource management systems, including production facilities. The research analyzed two manufacturers in Jinju, South Korea: Company A(not implemented smart factory technology, medium automation level) and Company B(implemented smart factory technology, high automation level). The results recommended simultaneous training for both enterprise operations and production management personnel for introducing the smart technology; and advised to retain more control over information security to advance the strategy. The research emphasized the importance of networking between companies and industries via a digital platform and the cooperation among manufacturers, logistics, academia and governments.