부갑상선 낭종 2예

성기영,백종민,이도상,오세정,김욱,박일영,원종만,전정수,Gi Young Sung,Jong Min Baek,Do Sang Lee,Se Jeong Oh,Wook Kim,Il Young Park,Jong Man Won,and Chung Soo Chun 대한갑상선-내분비외과학회 2005 The Koreran journal of Endocrine Surgery Vol.5 No.1

극지환경성능시험설비를 활용한 저온환경 시스템 구축

성기영,한성종,이정희,Sung, Ki-Young,Han, Seong-Jong,Lee, Jung-Hee 한국산업융합학회 2022 한국산업융합학회 논문집 Vol.25 No.5

This paper was conducted to study the conditions for the manufacture and operation of artificial snow removal and ice-making test facilities so that the test equipment can be tested in a low-temperature environment using the polar environment performance test facility. The polar environment performance test Facility is designed to artificially simulate extreme environments up to -65 ℃, and is a mid-to-large low-temperature environment test facility that can perform performance tests on offshore plant equipment, ships, leisure, and offshore structures. To verify the safety of deck work of ships operating in polar environments, artificial snow removal and artificial ice making devices were manufactured, and we conducted research on various operating environments using these facilities. For the efficient operation of artificial snow and ice making facilities, it is important to continuously supply dry air, and it has been found that installing an additional heater at the tip of the nozzle is effective in preventing freezing.

유한요소법을 이용한 과도 선형 동탄성 해석

성기영,이성희,심우진 金烏工科大學校 2000 論文集 Vol.21 No.-

The Finite element methods have been applied to various problems of interest, as witnessed by the extensive literature currently available. Transient linear elasto-dynamic problems are solved in a time domain by the FEM, for which the finite element equations are derived from the weak formulation based on the differential equations of motion using a stable time integration scheme known as the Newmark method, where the dependent variables are semidiscretized in series of the products of the spatial and temporal functions. The wave propagation problems by two and three dimensional and axisymetric models are analyzed to show the versatility of the presented formulation, resulting in good and stable numerical results.

액와접근법과 흉부접근법을 통한 내시경 갑상선 절제술의 임상적 고찰

성기영,오세정,백종민,이도상,김욱,박일영,원종만,Gi Young Sung,M,D,Se Jeong Oh,M,D,Jong Min Baek,M,D,Do Sang Lee,M,D,Wook Kim,M,D,Il Young Park,M,D,and Jong Man Won,M,D 대한갑상선-내분비외과학회 2004 The Koreran journal of Endocrine Surgery Vol.4 No.1

Purpose: The thyroid suregry has recently become one of the newest fields for the application of endoscopic surgery. We have performed endoscopic thyroidectomy by an anterior chest approach and an axillary approach. In this study, we evaluated these two types of endoscopic procedures with regard to efficacy and patients' complaints after surgery.Methods: Between December 2000 and March 2002, 41 patients were treated by endoscopic thyroidectomy via axillary or anterior chest approach. Each procedure was performed by one surgeon under a general anesthesia. We analysed the operating time, postoperative complications, postoperative scar, the degree of pain to assess the surgical invasiveness of each procedure.Results: Three cases treated using anterior chest approach, and 2 cases treated using axillary approach were converted to conventional thyroidectomy. The mean age of patients was 36 years in anterior chest approach group and 30 years in axillary approach group. The operation time was 238⁑60 (160∼370) minutes in anterior chest approach and 178⁑71 (100∼295) minutes in axillary approach. Postoperative complications are; 1 case of a minimal hematoma, 3 cases of minor wound infection, 3 cases of chest pain in anterior chest approach group, and 1 case of a minimal hematoma, 1 case of transient recurrent laryngeal nerve injury, 1 cases of transient swallowing difficulties in axillary approach group.Conclusion: Endoscopic (gasless and axillary approach) thyroidectomy is a safe and effective procedure. Gasless endoscopic thyroidectomy is a useful procedure for unexperienced surgeon due to safety. Endoscopic thyroidectomy by the axillary approach is a better effective procedure with good cosmetic result for a unilateral tumor especially in young women. (Korean J Endocrine Surg 2003;4:26-30)

선천성 하대정맥 결손과 C677T Methlenetetrahydrofolate Reductase Homozygos Mutation에 의한 고호모시스테인혈증이 동반된 환자에서 발생한 심부정맥혈전증

성기영,김기환,김지일,안창혁,김정수,유승진,임근우,원종만,고용복,장석효 대한혈관외과학회 2003 Vascular Specialist International Vol.19 No.2

Retinex를 이용한 빛의 변화에 안정적인 모션추적 콘텐츠연구

성기영,양황규,Sung, Ki-Young,Yang, Hwang-Kyu 한국전자통신학회 2011 한국전자통신학회 논문지 Vol.6 No.2

본 논문에서는 Retinex를 이용하여 객체의 추적을 할 때, 빛의 변화에 안정적으로 대응할 수 있게 하는 시스템을 제안한다. 기존의 인터렉션 시스템들은 한정된 공간 안에서 빛의 변화가 없는 상태를 구성을 하여 콘텐츠의 작동이 이루어졌기 때문에 빛의 변화에 대한 대응을 하지 않았다. 하지만 빛의 변화가 있는 실내에서 이러한 인터렉션 콘텐츠들이 작동할 경우 시간에 대한 빛의 투입량이 바뀌게 된다. 빛의 변화에 민감한 카메라를 통해 객체를 추적할 경우 약간의 빛으로 시스템이 오작동 하는 경우가 있으므로 빛의 변화는 시스템의 작동에 많은 영향을 미치는 요소 중의 하나이다. 본 논문에서는 이러한 빛의 변화를 안정적이고 일정한 처리를 위해 Retinex 알고리즘을 이용한다. This paper depict the system which reacts staly towards light changes, when object is detected using retinex. Previous interaction system does not react to transient light conditions. Since non-lighting condition was constructed in the limited space. However, if interaction contents work in the inside where the light changes, the light input is changed as the time goes by when the system detect objects with super sensitive camera few lighting transients makes system trouble. Thus, lighting is one of the most significant factors of the system.

위상형 CGH(computer generated hologram)를 이용한 비구면 파면 및 Bessel beam 제작

성기영,경천수,이영락,이정훈,이상조,곽종훈 영남대학교 기초과학연구소 2000 基礎科學硏究 Vol.20 No.-

We have designed and fabricated computer generated holograms(CGH) to generate ashepheric wavefront and Bessel beam. Designed CGH is recorded onto the photopolymer which is used as a volume hologram material mating CGHOE(computer generated holographic optical element). To investigate properties of fabricated CGHOE, intensities of Bessel beam are measured as a function of propagation(z-axis) and transverse (x-axis) distances.

위암에서 P16 및 hMLH1 유전자의 메틸화

성기영,전경화,송교영,김진조,진형민,김욱,박조현,박승만,임근우,박우배,김승남,전해명,Sung, Gi-Young,Chun, Kyung-Hwa,Song, Gyo-Yeong,Kim, Jin-Jo,Chin, Hyung-Min,Kim, Wook,Park, Cho-Hyun,Park, Seung-Man,Lim, Keun-Woo,Park, Woo-Bae,Kim, Seun 대한위암학회 2005 대한위암학회지 Vol.5 No.4

목적: 위암조직에서 P16과 hMLH1 유전자의 메틸화상태를 검사하여 위암의 발생과정에서의 작용과 유전자의 발현에 미치는 영향과 Helicobacter paylori균 감염여부 및 임상병리학적인자와의 연관성을 알아보고자 하였다. 대상 및 방법: 위암 신선 동결 절편조직 100예를 대상으로 유전자의 단백질 발현상태는 면역조직화학 염색을 시행하여 확인하였고. 메틸화 상태는 methylation-specific PCR(MSP)과 염기서열분석을 시행하였다. 결과: P16유전자의 메틸화는 19예(19%)에서 관찰되었고 이 중 18예(94.7%)에서 P16유전자의 단백질 발현 소실이 있어, P16 유전자의 단백질 발현 소실이 P16유전자의 메틸화와 연관이 있음을 알 수 있었다(kappa 계수=0.317, P=.0011). hMLH1 유전자의 메틸화는 27예(27%)에서 관찰되었고, 이 중 24예(8.8%)에서 hMLH1 단백의 소실이 hMLH1유전자의 메틸화와 연관이 있음을 보여주었다(kappa계수=0.675, p<0.0001). hMLH1 유전자의 메틸화는 나이, 암종의 크기, Lauren 분류와 연관성이 있었다. P16 유전자와 hMLH1 유전자 메틸화 모두 Helicobacter paylori균 감염여부와는 연관성이 없었다. 결론: 위암에서 P16 및 hMLH1 유전자의 불활성화에는 DNA 메틸화가 작용을 함을 알 수 있었고, hMLH1유전자의 메틸화는 나이, 암종의 크기, Lauren 분류와 연관이 있음을 알 수 있었다. Purpose: We investigated the impacts of the methylation states of the P16 and the hMLH1 genes on pathogenesis and genetic expression of stomach cancer and their relationships with Helicobater pylori infection, and with other clinico-pathologic factors. Material and Methods: In our study, to detect protein expression and methylation status of the P16 and the hMLH1 genes in 100 advanced gastric adenocarcinomas, used immunohistochemical staining and methylation-specific PCR (MSP) and direct automatic genetic sequencing analysis. Results: Methylation of the P16 gene was observed in 19 out of 100 cases (19%) and in the 18 of those cases (94.7%) loss of protein expression was seen. We were sble to show that loss of P16 gene expression was related to methylation of the P16 gene (kappa coefficient=0.317, p=0.0011). Methylation of the hMLH1 gene was observed in 27 cases (27%), and in 24 cases of those 27 cases (88.8%), loss of protein expression was seen, which suggested that loss of protein expression in the hMLH1 gene is related to methylation of hMLH1 gene (kappa coefficient=0.675, P<0.0001). Also methylation of the hMLH1 gene was related to age, size of the mass, and lauren's classification. Conclusion: We found that methylation of DNA plays an important role in inactivation of the P16 and the hMLH1 genes. The methylation of the hMLH1 genes is significantly related to age, size of the mass, and lauren's classification.

위암의 재발양상에 따른 혈관내피성장인자의 발현

성기영,박일영,이도상,김욱,백종민,신동준,원종만,이재학,Sung Gi Young,Park Il Young,Lee Do Sang,Kim Wook,Baek Jong Min,Shin Dong Jun,Won Jong Man,Lee Jai Hak 대한위암학회 2002 대한위암학회지 Vol.2 No.4

Purpose: Angiogenesis is essential for tumor growth and metastasis and depends on the production of angiogenic factors that are secreted by tumor cells. Vascular endothelial growth factor (VEGF) is the most significant angiogenic factor and a selective mitogen for endothelial cells. VEGF, also known as the vascular permeability factor, acts on endothelial cells to increase microvascular permeability and directly stimulate the growth of new blood vessels. Several studies have reported that the expression of VEGF is correlated with hematogenous recurrence via angiogenesis in gastric carcinomas. This research evaluated the relationship between the expression of VEGF and hepatic and peritoneal recurrence in gastric carcinomas. Materials and Methods: Thirty specimens resected from patients with primary gastric carcinomas who had undergone curative resections were divided into three group: Group I, early gastric carcinomas without recurrence; Group II, advanced gastric carcinomas with hepatic recurrence; and Group III, advanced gastric carcinomas with peritoneal recurrence. The expression of VEGF and the density of the microvessel count were examined using immunohistochemistry. Results: 1) The expression of VEGF in Group II and Group III ($63.2\pm\24.3\%$) was stronger than that in Group I ($7\pm\4.2\%$). The expression of VEGF in Group II ($76.5\pm\13.2\%$) was stronger than that of the Group III ($50\pm\14.2\%$) (P<0.05). 2) The microvessel count in Group II ($49.9\pm14.5$) was more than that in Group I ($8.6\pm2.6$) and Group III ($29.1\pm18.1$) (P<0.05). 3) The microvessel count was increased significantly with increasing the expression of VEGF. Conclusions: The expression of VEGF is associated with advanced stomach cancer and hepatic recurrence has a higher expression of VEGF than peritoneal recurrence with neovascularization. Thus the expression of VEGF can be considered to be a useful indicator of recurrence in gastric carcinoma and especially in hepatic recurrence.

이슈 연계를 통해 본 역대 정부의 대북한 정책 분석: "교환 모델"과 "촉매 모델"

성기영 ( Ki Young Sung ) 북한연구학회 2012 北韓硏究學會報 Vol.16 No.2

본 논문은 김영삼 정부 이후 이명박 정부까지 지난 20년간의 대북 정책을 경제와 안보 이슈의 연계 또는 탈연계라는 틀로 분석한 후 문제점을 발견하는 것을 목적으로 한다. 이를 위해 미로슬라브 닌식(Miroslav Nincic)이 제시했던 ``교환 모델(exchange model)``과 ``촉매 모델(catalyst model)``을 바탕으로 대북 개입 정책의 공과를 평가한다. 평가결과 김영삼 정부와 이명박 정부의 이슈연계 방식에 상당한 유사성을 있다는 사실을 발견하고 이를 세 가지로 요약한다. 첫째, 경제와 안보 이슈의 연계를 통해 북한으로부터 얻어내고자 하는 행동 변화가 무엇인지 정확하게 정의되지 않았다. 둘째, 복수의 이슈 영역이 공존할 수있는 구조적 모멘텀을 유지하는 데 실패했다. 셋째, 단기적 차원에서 북한의 태도 변화를 이끌어내는 데 집중했을 뿐정치적 비용에 대한 이해를 결여한 채대북정책의 장기적 일관성을 유지하는 데 실패했다. 이러한 연구 결과를 바탕으로 본 논문은 남북관계의 제도화를 위해경제-안보 이슈의 직접적 연계는 지양되어야 한다는 결론을 유도한다. This paper aims to identify a series of problems in pursuing South Korea`s foreign policy towards North Korea by examining the policy from the Kim Young Sam to the Lee Myung-bak administration from the perspective of issue-linkage. To this end, the author evaluated the engagement policy by the South Korean governments based on the notion of ``exchange model`` and ``catalyst model`` proposed by Miroslav Nincic. This paper finds that the Kim Young Sam and Lee Myung-bak adminstration showed significant similarities in terms of the way they linked economy and security issues each other in conducting their North Korea policy. First, they failed to precisely define a behavior change of Pyongyang they wanted to see by linking security and economy issues in dealing with North Korea. Second, they failed to keep a momentum in which multiple issue areas could coexist. Third, they paid scant attention to maintain consistency in North Korea policy and only obsessed to elicit North Korea`s behavior change on a short term basis. They lacked understanding that it is inevitable to see North Korea`s economic capability enhancement as a result of the pursuit of engagement policy. This paper concludes, based on the findings above, that issue-linkage between security and economy in North Korea policy should be avoided in order to institutionalize inter-Korean relations.