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급성 골수성 백혈병에서 고용량 Cytarabine 을 이용한 공고요법
김도하(Do Ha Kim),이규형(Kyoo Hyung Lee),조재근(Jae Kun Cho),김선희(Seon Hee Kim),이제환(Je Hwan Lee),김성배(Sung Bae Kim),김상위(Sang We Kim),서철원(Chul Won Suh),이정신(Jung Shin Lee),김우건(Woo Kun Kim),김상희(Sang Hee Kim) 대한내과학회 1996 대한내과학회지 Vol.51 No.4
N/A Objectives: This study was designed to evaluate the therapeutic efficacy of postremission therapy utilizing high-dose cytarabine in patients with newly diagnosed acute myelogenous leukemia and to assess the toxicities of the therapy. Acute promyelocytic leukemia (FAB M3) is excluded because it has very unique clinicopathologic characteristics. Methods: Those patients who achieved complete remission had first consolidation therapy with conventional dose cytarabine and daunorubicin but second and third consolidation was done with high-dose cytarabine (cytarabine 1gm/㎡ i.v. over 1 hour every 12 hours daily for 5 days) and daunorubicin. Overall survival and disease free survival were compared with previous conventional dose cytarabine and daunorubicin postremission therapy. Results: 1) Complete remission occurred in 62% (28 of 45 patients) and control group 48% (14 of 29 patients) (p=0.15). 2) The median survival of all 45 patients was not different significantly compared with control group (10 months vs 7 months, p=0.08). 3) The median disease free survival of 21 complete responders receiving at least one course of consolidation was 10 months and there was no significant difference compared with control group 7 months (p=0.47). 4) The toxicity including treatment-related motility, neutropenia duration was similar in both groups. Conclusion: Although our high-dose cytarabine consolidation therapy regimen appeared to have acceptable toxicity, its results did not show the superiority to previous conventional dose cytarabine consolidation regimen.
3차원 인텐시티 프로브의 근거리 음장 측정에서의 오차 수치해석
김석재,지석근,김천덕,Kim, Suk-Jae,Jee, Suk-Kun,Suzuki, Hideo,Kim, Chun-Duck 한국음향학회 1994 韓國音響學會誌 Vol.13 No.3
이 연구에서는 3차원 음향 인텐시티를 동시에 측정할 수 있는 프로브를 이용하여 음향 인텐시티를 측정할 때 필연적으로 발생하는 오차를 컴퓨터의 수치계산으로 검토하였다. 이 3차원 음향 인텐시티 프로브는 Suzuki등에 의해 제안된 4개의 마이크로폰으로 구성된 것이고, 수치계산에서는 이상적인 점음원과 유한 크기를 가지는 면음원에 대해서 프로브의 각 축방향 및 임의의 방향에 대한 측정오차를 근거리 음장에서 분석하였다. 그 결과, 점음원의 경우 측정거리가 프로브를 구성하는 마이크로폰 사이의 간격보다 약 2.5배 이상 떨어진 거리에서 오차 1dB 이하의 정밀한 측정을 할 수 있었고, 유한 크기의 면음원의 경우, 면음원의 한 변의 길이가 0.02m이상일 때 근거리 음장의 측정오차가 크게 감소하기 시작하여, 한 변의 길이가 0.2m일 때 측정거리가 마이크로폰 사이의 간격보다 0.67배로 근접하여 측정하여도 1dB 이하의 정밀한 측정이 가능한 것으로 평가되어 이 프로브의 근거리 음장 측정의 유효성이 확인되었다. We studied an inherent error be caused by a measuring acoustic intensity using probe which can measure simultaneously the three-dimensional acoustic intensity. This three-dimensional intensity probe was constructed with four microphones, proposed by Suzuki et al. . In the computer simulation, we analyzed the nearfield measurement error with arbitary direction and each of axis direction on the ideal point source and the plate sound source which have finite size. From the results, in case of point source, we obtained accurate measurement below about 1dB when the distance of measurement was about 2.5 times with the distance among microphones in this probe. And in the case of plate sound source, the nearfield measurement error was decreased as the length of one side became above 0.02m, we obtained accurate measurement below about 1dB when the length of one side is 0.2m. The nearfield measurement error of finite size sound is small to ignore. Therefore this probe is useful to measure nearfield intensity.
도시유역에서 공간적으로 분포된 소규모 강우유출수 관리시설의 최적설치위치선정
김상단 ( Sang Dan Kim ),임용균 ( Yong Kun Lim ),김진관 ( Jin Kwan Kim ),강두기 ( Doo Kee Kang ),서성철 ( Seong Cheol Seo ),이재관 ( Jae Kwan Lee ) 한국물환경학회 2010 한국물환경학회지 Vol.26 No.6
Spatially distributed on-site devices such as bioretentions and bioboxfilters are becoming more common as a means of controlling urban stormwater quality. One approach to modeling the cumulative catchment-scale effects of such devices is to resolve the catchment down to the scale of a land parcel or finer, and then to model each device separately. The focus of this study is to propose a semi-distributed model for simulating urban stormwater quantity and identifying best sites for spatially distributed on-site stormwater control devices in an urban drainage system. A detailed model for urban stormwater improvement conceptualization simulation is set up for a 0.9342 km(2).
절연고분자 polystyrene 혼합에 의한 TIPS-pentacene OTFT의 성능 개선
김재선(Jae Seon Kim),송정근(Chung Kun Song) 대한전자공학회 2013 전자공학회논문지 Vol.50 No.7
본 논문에서는 절연 고분자 polystyrene(PS)을 TIPS-pentacene 용액에 혼합하여 OTFT를 제작하였고, PS의 분자량과 함량이 소자 성능에 미치는 영향을 분석하였다. 분자량 9,580의 PS가 분자량이 큰 것 보다 우수한 성능을 나타내었다. 그리고 함량은 0.3 wt%일 때 전계이동도는 1.0 ± 0.19 ㎠/V?sec, 부문턱전압기울기는 0.22 ± 0.05 V/dec, 문턱전압은 ?1.19 ± 1.21 V, 그리고 전류점멸비는 7.12 ± 2.09 × 106 이었으며, PS를 혼합하지 않은 OTFT에 비하여 약 5배의 성능 개선이 있었다. 또한 잉크젯 공정에서 기판온도는 커피링을 제거하는 중요한 요소이며 PS를 혼합한 TIPS-pentacene의 적합한 온도는 46 ℃로 확인되었다. In this paper we analyzed the effects of polystyrene(PS) blended in TIPS-pentacene on the performance of OTFTs. With the various molecular weight and the content of PS the performance of TIPS-pentacene OTFTs was examined and the proper molecular weight and the content were extracted for the best results. With the molecular weight of 9,580 and 0.3 wt% of PS OTFTs produced the mobility of 1.0 ± 0.19 ㎠/V?sec, the subthreshold slope 0.22 ± 0.05 V/dec, the threshold voltage ?1.19 ± 1.21 V, the current on/of ratio 7.12 ± 2.09 × 10?. Additionally the suitable substrate temperature for ink jet printing of the blended TIPS-pentacene OTFTs was also extracted and it was 46 ℃.
동부류 근류균(根瘤菌)의 땅콩에 대한 근류형성(根瘤形成)과 질소고정(窒素固定)
김무기,박건호,소재돈,최대웅,Kim, Moo-Key,Park, Kun-Ho,So, Jae-Don,Choi, Dae-Ung 한국토양비료학회 1992 한국토양비료학회지 Vol.25 No.1
국내에서 분리(分離)된 73개의 땅콩 근류균(根瘤菌)과 31개의 도입된 Cowpea 근류균(根瘤菌)의 국내 땅콩 장려 품종(品種)에 대한 접종효과를 온실실험으로 조사하였던바 근류형성(根瘤形成)과 건물생산량 및 총(總) 질소함량(窒素含量)에서 다양한 변화(變化)를 보였다. 총(總) 건물생산량과 총(總) 질소함량(質素含量)의 서열간에 가장 높은 상관관계가 있었다. 조사된 균주중(菌株中)에서 51.9%, 26.4%, 21.7%가 각각 우량균주(優良菌株), 보통균주(普通菌株), 및 불량균주(不良菌株)로 나타났으며, JB7을 포함한 6개 균주가 가장 우수했다. 조사된 균주(菌株)는 YMA배지상에서의 생장특성에 따라 5개의 군(群)으로 분리되었다. Glasshouse experiments were conducted to evaluate nodulation, and $N_2$ fixation of 73 strains of Bradyrhizobia isolated from nodules of groundnuts and/or cowpeas grown at various location in Korea and 31 strains of cowpea Bradyrhizobia obtained from overseas sources. Of the strains tested 51.9%, 26.4%, and 21.7% were rated fully effective, partially effective, and ineffective, respectively. Eight very effective strains were selected. Nodulation, shoot dry mass, whole plant dry mass, and plant total N content were significantly correlated with each other. The highly significant correlation of total N content and plant dry mass ($r=0.98^{**}$) indicates that plant dry mass can be used as a measure of strain effectiveness in preliminary test.