노동법상의 해고제한의 법리

김소영 한국국민윤리학회 1987 倫理硏究 Vol.25 No.1

Plasma Neutrophil Gelatinase-Associated Lipocalin as a Marker of Tubular Damage in Diabetic Nephropathy

김소영,정태동,이우창,전사일,선우성,김순배,민원기 대한진단검사의학회 2018 Annals of Laboratory Medicine Vol.38 No.6

Background: An increase in neutrophil gelatinase-associated lipocalin (NGAL) indicates tubular injury. Diabetic nephropathy causes typical changes in the kidney, characterized by glomerulosclerosis and eventual tubular damage. We validated the usefulness of plasma NGAL (pNGAL) as a biomarker of tubular damage in patients with diabetic nephropathy. Methods: We included 376 patients with diabetes mellitus (260 patients with chronic renal insufficiency who had not received hemodialysis and 116 hemodialyzed due to diabetic nephropathy) and 24 healthy controls. Patients with chronic renal insufficiency were divided into three groups according to urinary albumin excretion (UAE) levels. pNGAL levels were measured using the Triage NGAL test (Alere, San Diego, CA, USA) and were compared between groups. We also examined whether pNGAL level was related to the degree of albuminuria and cystatin C-based glomerular filtration rate (GFR). Results: Mean pNGAL levels of the healthy controls, chronic renal insufficiency patients with diabetes mellitus, and hemodialyzed patients were 61.9±5.3 ng/mL, 93.4±71.8 ng/mL, and 1,536.9±554.9 ng/mL, respectively. pNGAL level increased significantly in patients with severe albuminuria (P<0.001) and had a moderate correlation with the degree of albuminuria (r=0.467; P<0.001) and GFR (r=0.519; P<0.001). Multivariate regression analysis showed that the pNGAL level was associated with tubular damage independent of patient age, sex, and GFR. Conclusions: pNGAL level independently reflects the degree of tubular damage in patients with diabetic nephropathy. Measurement of pNGAL, combined with UAE, would enable simultaneous, highly reliable assessments of tubular damage for such patients.

차단주파수 영역 도파관 등가회로 모델을 이용한 Gap-Coupled NRD Guide 대역통과 여파기의 설계

김소영,이정해 한국전자파학회 2000 한국전자파학회논문지 Vol.11 No.6

As the interest in the millimeter wave frequency (30 ~300 GHz) increases, Nonradiative Dielectric (NRD) guide is being more attractive due to its low loss characteristics. Most of millimeter wave components, which can be realized with waveguide, can also be realized with NRD guide since NRD guide has similar dispersion characteristics and field patterns to waveguide. Previously, Variational Method was applied to the gap discontinuity problem to design a gap-coupled NRD bandpass filter. In this paper, the design procedure was simplified by replacing the air gap region with an equivalent circuit model of an evanescent waveguide using the fact that the NRD guide has a similar structure with a dielectric-filled metal waveguide. Prior to applying this design method to the bandpass filter of millimeter wave frequency range, a bandpass filter of which center frequency is 10 GHz(3-Pole, 0.1 dB ripple, 2% fractional bandwidth) was designed and fabricated. The measured result agrees with one simulated with HFSS within an error range of a fabrication.

한국 남해 광양만 퇴적물에서 와편모조류 시스트의 수직적 군집 분포

김소영,문창호,조현진 한국수산과학회 2003 한국수산과학회지 Vol.36 No.3

맞벌이 가정의 일‐가정 양립의 양상과 조화로운 양립의 가능성 탐색 연구

김소영,김선미,이기영 한국가족자원경영학회 2011 가족자원경영과 정책 Vol.15 No.1

응축형 복합레진의 파괴거동에 관한 연구

김소영,최호영,최경규,박상진 대한치과보존학회 2000 Restorative Dentistry & Endodontics Vol.25 No.3

In this study, compressive strengths of three condensable composite resins(ALERT, SureFil. Solitaire), conventional hybrid composite resin(Z-100) and amalgam(HI-Aristaloy 21) according to the 6 types of cavity design(cylinder, trapezoidal, butt-joint, round bevel, long bevel and short bevel) were measured and appearance of fracture surfaces were observed with SEM, thus evaluated clinical applications of condensable composite resins according to the cavity designs. The results were as follows: 1.Compressive strengths according to experimental materials were the highest in SureFil, and Z-100, ALERT, Solitaire, Hl-Aristaloy 21 in order. 2.SureFil showed the highest compressive strength(p〈0.05) , compressive strengths of ALERT and Solitaire were lower than that of Z-100, hybrid composite(p〈0.05) . 3.Compressive strengths according to specimen design were the highest in trapezoidal shape(p〈0.05) and no significant difffrence was detected between other specimen designs. 4.The appearance of condensable composite resin under SEM was of a diverse configuration according to component of resin matrix, shapes of filler and surface treatments between resin and filler.

대학생의 스트레스와 학교생활 만족도 관계에 대한 자아개념과 종교의 조절효과

김소영 한국열린교육학회 2013 열린교육연구 Vol.21 No.1

본 연구는 서울특별시에 소재한 4년제 두 대학에서 표집 된 189명의 대학생을 대상으로 스트레스, 학교생활 만족도, 사회 자아개념, 가족 자아개념, 종교유무 변인의 성별 간 차이를 살펴보고, 대학생의 스트레스와 학교생활 만족도 관계에 대한 자아개념과 종교의 조절효과를 남녀 학생의 성별로 구분하여 탐색하였다. 전체학생 중 남학생은 132명(69.8%), 여학생은 57명(30.2%)이었다. 전체학생의 대학생활 만족도는 보통수준(3.21/5)이었고, 스트레스 정도는 낮은 편(평균=1.80/4)이었다. 학생들은 대체적으로 사회적 측면(3.10/4), 가족과의 관계 (3.37/4)에서 자신들을 긍정적으로 인식하고 있었다. 다른 변인들은 성별 간 평균차이가 없었으나, 사회 자아개념은 남학생이 여학생 보다 통계적으로 유의미하게 높았다. 스트레스와 학교생활 만족도 관계에 대한 자아개념과 종교 유무의 조절효과는 성별에 따라 다르게 나타났는데, 여학생 집단에서만 사회 자아개념의 조절효과가 있었다. 여학생 집단에서 사회 자아개념이 높은 경우, 대학생활 만족도에 대한 스트레스의 영향력은 사회 자아개념이 낮은 경우에 비해 작았고, 스트레스가 높은 상황에서 사회 자아개념이 높은 학생의 대학생활 만족도는 사회 자아개념이 낮은 경우에 비해 높았다. 또한, 여학생 집단에서 종교가 없을 때 오히려 조절효과가 관찰되어 종교가 없는 경우 대학생활 만족도에 대한 스트레스의 영향력이 작았다. The purpose of the study is to investigate the moderating effects of self-concept (social and family) and religion on the relationship between daily stress and school-life satisfaction for College students. This study also analyzed the relationship (Pearson r) and the mean difference of these variables by gender. The study participants were 189 college students from two four-year universities located in Seoul. There were 132 (69.8%) male college students and 57 (30.2%) female students. The school-life satisfaction of the entire students was a moderate level(3.21/5), and the degree of stress was less than normal levels (1.80/4). Students positively perceived their social self-concept and family self-concept. The results are as follows. Firstly, there was no difference between the variables with respect to gender except for social self-concept. Social self-concept for male students was statistically higher than that of female students. Secondly, the moderating effects of self-concept were depending on the gender. The moderating effect of social self-concept was detected only in the female group. When the social self-concept was higher, the influence of the stress on school-life satisfaction was low compared to smaller social self-concept group. In both groups, when there were no religious beliefs, the moderating effects were observed. That is, when there is no religious beliefs, the influence of stress on school-life satisfaction was small.

고해상도 방사선 영상을 위한 $Gd_2O_3:Eu^{3+}$ 나노 형광체 제조 및 광학적 특성

김소영,강상식,박지군,차병열,최치원,이형원,남상희,Kim, So-Yeong,Kang, Sang-Sik,Park, Ji-Koon,Cha, Byung-Youl,Choe, Chi-Won,Lee, Hyung-Won,Nam, Sang-Hee 대한의용생체공학회 2007 의공학회지 Vol.28 No.1

In this paper, we have synthesized $Gd_2O_3:Eu^{3+}$ nano phosphor particle using a low temperature solution-combustion method. We have investigated the structure and the luminescent characteristic as the sintering temperature and europium concentration. From XRD(X-ray diffraction) and SEM(scanning electron microscope) results, we have verified that the phosphor particle was fabricated a spherical shape with $30{\sim}40nm$ particle size. From the photoluminescence results, the strong peak exhibits at 611 um and the luminescent intensity depends on europium concentration. $Gd_2O_3:Eu$ fine phosphor particle has shown excellent luminescent efficiency at 5 wt% of europium concentration. The phosphors calcinated at $500^{\circ}C$ have possessed the x-ray peaks corresponding to the cubic phase of $Gd_2O_3$. As calcinations temperature increased to $700^{\circ}C$, the new monoclinic phase has identified except cubic patterns. From the luminescent decay time measurements, mean lifetimes were $2.3{\sim}2.6ms$ relatively higher than conventional bulk phosphors. These results indicate that $Gd_2O_3:Eu$ nano phosphor is possible for the operation at the low x-ray dose, therefore, the application as medical imaging detector.

박태기나무의 잎으로부터 피부멜라닌 색소생성 억제성분의 분리

김소영,김진준,장태수,정시련,이승호,Kim, So-Young,Kim, Jin-Joon,Jang, Tae-Soo,Chung, See-Ryun,Lee, Seung-Ho 한국생약학회 1999 생약학회지 Vol.30 No.4

Tyrosinase plays an important role in the process of melanin polymer biosynthesis. Therefore, the enzyme inhibitors have been of great concern as cosmetics to have skin-whitening effects on the local hyperpigmentation. During the search for new inhibitory compounds on melanin polymer biosynthesis from natural sources, MeOH extracts of 589 higher plants were tested for the inhibitory effect on tyrosinase activity by the muschroom tyrosinase assay in vitro. Among plants tested, the leaves of Cercis chinensis exhibited potent inhibitory effect on mushroom tyrosinase activity. Subsequently seven active compounds were isolated from the ethyl acetate soluble part of acetone extract of the leaves of C. chinensis by the activity guided fractionation monitoring the inhibitory effect on tyrosinase activity. Their chemical structures were identified as $kaempferol-3-0-{\alpha}-L-rhamnoside$, quercitrin, $myricetin-3-0-{\alpha}-L-rhamnoside$, myricetin-3-0-(2'-O-galloyl)- ${\alpha}$ -L-rhamopyranoside (desmanthin), (-)-epicatechin-3-0-gallate, (-)-epigallocatechin-3-0-gallate, and methyl gallate on the basis of the speculation of spectral data and chemical reaction. Among the flavonol rhamnosides, myricetin-3-0-(2'-O-galloyl)- -L-rhamnoside(desmanthin) showed most potent inhibitory effect on tyrosinase activity and the structure of B-ring in flavonol moiety was related to the activity. (-)-Epigallocatechin-3-O-gallate having pyrogallol group in flavan-3-ol moiety exhibited more potent inhibitory effect than (-)-epicatechin-3-0-gallate having catechol group in flavan-3-ol moiety on mushroom tyrosinase activity.

Astaxanthin의 용해특성 및 저장 안정성

김소영,조은아,유지민,인만진,채희정 한국생물공학회 2008 KSBB Journal Vol.23 No.6

Basic characteristics of astaxanthin including solubility and stability were investigated. Astaxanthin showed a very poor solubility in water, but it was highly soluble in organic solvents such as acetone and acetic acid. The solubility of astaxanthin in acidic condition was 10-20 times higher than those in neutral and basic conditions. Astaxanthin was very unstable in acidic condition under UV irradiation and in the presence of oxygen. Also, heating even for a very short time accelerated the degradation of astaxanthin. In conclusion, it is required to enhance the water-solubility and stability of astaxanthin for industrial application in food and cosmetic area.