초극소 저출생 체중아의 최근 치료 성적 - CRIB(clinical risk index for babies) II 점수를 이용한 생존율 분석 -

김도현,심소연,김재리,신승한,김은선,정경은,김상덕,이진아,최창원,김이경,김한석,김병일,최중환,Kim, Do-Hyeon,Shim, So-Yeon,Kim, Jae-Ri,Shin, Seung-Han,Kim, Eun Sun,Joung, Kyoung-Eun,Kim, Sang Duk,Lee, Jin A,Choi, Chang Won,Kim, Ee-Kyung,Kim, H 대한소아청소년과학회 2006 Clinical and Experimental Pediatrics (CEP) Vol.49 No.9

목 적 : 최근 들어 출생체중 1,000 g 미만으로 태어난 ELBWI의 생존율은 주산의학 및 신생아학의 발달로 인해 증가하고 있다. 저자들은 최근 6년간 서울대학교병원에서 태어난 ELBWI의 생존율 변화를 분석하여 신생아 집중 치료술의 향상여부를 알고자 하였다. 방 법 : 본 연구에 포함된 99명의 ELBWI은 출생 년도에 따라 세 시기(I기 : 2000-2001년, II기 : 2002-2003년, III기 : 2004-2005년)로 나누어졌다. 세 시기의 임상적 중증도를 보정하기 위해 CRIB II 점수 체계를 이용하여 ELBWI의 생존율을 비교하였다. 결 과 : ELBWI의 전체 생존율은 74.7%였고, 세 시기에 걸쳐 생존율은 지속적으로 향상되었다(I기 : 60.7%, II기 : 73.3%, III기 : 85.3%). 최소한 50% 이상이 생존하는 것으로 정의된 생존한계는 출생체중 600 g대, 재태기간 25주였다. 출생체중 750 g 미만인 경우에는 세 시기에 걸쳐 생존율이 전체 생존율에 비해서 매우 두드러지게 증가하였다(I기 : 10%, II기 : 46.2%, III기 : 70.6%). ELBWI의 세 시기에 걸친 지속적인 생존율 향상은 CRIB II 점수로 보정한 후에는 더 뚜렷해졌다. 결 론 : 본 기관에서 최근 6년간에 걸친 ELBWI의 생존율은 지속적으로 향상되는 경향을 보였고, 이러한 경향은 특히 출생체중 750 g 이하에서 두드러졌다. 이러한 생존율 향상은 ELBWI의 임상적 중증도 개선과는 상관없이 이루어졌다. Purpose : The survival rate of infants weighing less than 1,000 g at birth(extremely low birth weight infants, ELBWI) has increased due to recent advances in perinatal and neonatal intensive care. The purpose of this study was to evaluate the survival rates of ELBWI born at Seoul National University Hospital during the last six years. Methods : A total of 99 infants were divided into three groups(period I: 2000 to 2001, period II: 2002 to 2003, period III : 2004 to 2005) based on date of birth. We compared the survival rate of ELBWI over the three periods, using CRIB II score for adjustment for clinical severity. Results : Overall survival rate of ELBWI was 74.7 percent. The survival rate of ELBWI increased over the three periods(period I: 60.7 percent, period II : 73.3 percent, period III : 85.3 percent). The threshold of viability(defined as survival of at least 50 percent of infants) was 25 weeks of gestation and 600 g at birth. The birth weight-specific survival rates increased considerably over the three periods for infants <750 g at birth(period I: 10 percent, period II: 46.2 percent, period III : 70.6 percent). The survival rates of ELBWI over the three periods increased much remarkably after adjustment for clinical severity by CRIB II score. Conclusion : In our institution, survival rates of ELBWI during the last six years continued to improve, particularly for infants weighing <750 g at birth. This increase in survival rates was not associated with the clinical severity of ELBWI.

키워드 커뮤니티 네트워크의 소셜 네트워크 분석을 이용한 사물 인터넷 특허 분석

김도현,김현희,김동건,조진남,Kim, Do Hyun,Kim, Hyon Hee,Kim, Donggeon,Jo, Jinnam 한국통계학회 2016 응용통계연구 Vol.29 No.4

본 연구에서는 한국과 미국의 사물 인터넷 관련 특허 초록을 수집하여 키워드 네트워크 및 키워드 커뮤니티 네트워크를 구축하고 네트워크 분석을 실시하였다. 먼저 TF-IDF 가중치를 적용하여 중요 키워드를 추출하고 이 중요 키워드와 상관관계가 높은 키워드들을 재추출하여 핵심 키워드를 선정하였다. 선정된 키워드를 중심으로 키워드 네트워크를 구축한 다음 네트워크 탐지를 시행하여 키워드 커뮤니티 네트워크를 재구축하여 기술 간의 연결 관계를 분석하였다. 본 연구에서 생성한 키워드 커뮤니티 네트워크는 특허의 내용을 예측할 수 있을 뿐만 아니라 커뮤니티 간의 연결 관계를 분석함으로써 기술 간의 연관 관계도 파악할 수 있다. 키워드 커뮤니티 네트워크 분석 결과 한국은 보안, 반도체, 이미지 프로세스와 같은 사물 인터넷의 기반 기술 분야의 특허가 중요한 특허 기술로 나타난 반면 미국의 경우 스마트 홈, 대화형 매체 그리고 통신 등과 같은 사물 인터넷 환경, 응용 분야의 기술이 중요한 기술로서 자리잡고 있음을 알 수 있다. In this paper, we analyzed IoT patent data using the social network analysis of keyword community network in patents related to Internet of Things technology. To identify the difference of IoT patent trends between Korea and USA, 100 Korea patents and 100 USA patents were collected, respectively. First, we first extracted important keywords from IoT patent abstracts using the TF-IDF weight and their correlation and then constructed the keyword network based on the selected keywords. Second, we constructed a keyword community network based on the keyword community and performed social network analysis. Our experimental results showed while Korea patents focus on the core technologies of IoT (such as security, semiconductors and image process areas), USA patents focus on the applications of IoT (such as the smart home, interactive media and telecommunications).

하이브리드 비좌굴가새의 진동제어능력에 관한 실험적 연구

김도현,주영규,김명한,성우기,김상대,Kim, Do Hyun,Ju, Young Kyu,Kim, Myung Han,Sung, Woo Gi,Kim, Sang Dae 한국강구조학회 2009 韓國鋼構造學會 論文集 Vol.21 No.1

Buckling Restrained Braces (BRBs) show good seismic behavior. They do not dissipate energy, however, when they are subjected to minor earthquakes or wind. Hybrid Buckling Restrained Braces (H-BRBs), which can improve the wind performance of the BRB system, are a kind of hybrid damper system composed of a viscoelastic damper and BRBs. In this paper, two H-BRB specimens with different cores were experimentally investigated to ensure the structural behavior of the H-BRB system in an elastic range. The axial deformation of the primary resisting system was compared with that of the secondary resisting system, and the equivalent damping ratio of the H-BRBs was estimated. It was concluded that H-BRBs with double shear dampers show good structural behavior and are applicable to tall buildings, to improve the building performance at a comfortable level. 비좌굴가새는 우수한 내진성능을 보이는 시스템이다. 그러나 비좌굴가새는 약진이나 바람과 같은 하중에 대하여 에너지를 소산시키지 못한다. 기존의 비좌굴가새의 풍저항 성능을 개선한 하이브리드 비좌굴가새(H-BRB)는 비좌굴가새와 점탄성댐퍼로 구성된 복합댐퍼시스템의 일종이다. 본 논문에서는 탄성영역에서 H-BRB의 구조성능을 확인하기 위하여 심재가 다른 두 개의 실험체에 대한 실험이 수행되었다. H-BRB 시스템에 대한 탄성영역에서의 거동메케니즘 검증을 위하여 주저항요소와 2차 저항요소의 축변형량과 에너지소산 능력을 비교하였다. 실험결과 댐퍼부에서 이면전단을 사용한 H-BRB는 우수한 구조성능을 보이며, 고층건물의 사용성 수준을 향상시키기 위하여 적용될 수 있을 것이다.

회전형 복합마찰댐퍼 구조거동에 대한 실험적 연구

김도현,김지영,김명한,Kim, Do-Hyun,Kim, Ji-Young,Kim, Myeong-Han 한국공간구조학회 2015 한국공간구조학회지 Vol.15 No.4

The new rotary friction damper was developed using several two-nodal rotary frictional components with different clamping forces. Because of these components, the rotary friction damper can be activated by building movements due to lateral forces such as a wind and earthquake. In this paper, various dependency tests such as displacement amplitude, forcing frequency and long term cyclic loading were carried out to evaluate on the structural performance and the multi-slip mechanism of the new damper. Test results show that the multi-slip mechanism is verified and friction coefficients are dependent on displacement amplitute and forcing frequency except long term cyclic loading.

산증후군환자에 대한 사이크로스포린의 유효성 및 안전성 평가를 위한 16주 공개 다기관 제 3상 임상시험

김도현,신규태,임천규(Chun Gyoo Ihm),조동규(Dong Kyu Cho),이태원(Tae Won Lee),김명재(Myung Jae Kim),김흥수(Heung Soo Kim),이호영(Ho Yung Lee),신석균(Sug Kyun Shin),홍성표(Seong Pyo Hong),노현진(Hyunjin Noh),김용림(Young Lim Kim) 대한신장학회 2000 Kidney Research and Clinical Practice Vol.19 No.2

N/A A multicenter prospective study was done in four-university hospital to evaluate the efficacy and safety of cyclosporin A(CyA, Cipol-N) in 64 patients with adult nephrotic syndrome mean age 34.8 years, male:female 2.4:1, duration of disease 38.0±40.9months, 31 patients with MCD, 33 patients with Non-MCD(8 FSGS, 14 MGN, 7 MPGN, 2 lupus nephritis, 1 HBsAg associated GN)]. The prior steroid responses of these patients were 17 steroid dependent, 9 frequent relapser, 4 steroid resistant and 1 other in MCD patients, and 5 steroid dependent, 5 frequent relapser, 22 steroid resistant and 1 other in Non-MCD patients. After a 2-week steroid(predni-solon 10mg/day or deflazacort 12mg/day) run-in period, CyA 5mg/kg/day and prednisolone 10mg/day (or deflazacort 12mg/day) were administered for up to 16 weeks. Of the 64 patients enrolled, ll patients were dropped out prematurely due to adverse events or protocol violation. Of the 53 patients who completed the study, 27 had MCD and 26 had Non- MCD. High response(CR and PR) rate of 68%(36/53) were obtained with CyA treatment in all patients. Although the response rate in MCD was significantly higher than that in Non-MCD(89 vs. 46%, p<0.05) and response rates were significantly different according to the previous steroid responses by univariate analysis, only previous steroid responses affected the response to CyA significantly by Logistic multiple regression analysis(p=0.03, RR 7.08); responses were 84%(27/32) in steroid dependent and frequent relapser patients, and 37%(7/19) in steroid resistant patients. 24-hr proteinuria significantly decreased after 2 weeks and serum albumin and cholesteroi increased significantly after 4 weeks of treatment compared to baseline level. The serum creatinine level was not changed during the study. No serious and unexpected side event was observed. In conclusion, cyclosporine therapy is a safe and effective mode of treatment in patients with ne-phrotic syndrome, especially in those who need pro- longed administration of steroids with resulting in unavoidable steroid complications such as frequent relapser and steroid dependent type. The patients with steroid resistant type and contraidications of steroid administration such as DM, aseptic bone neerosis etc. can also be candidates for this treatment.

홍용 문자 코드 집합을 위한 계층적 다중문자 인식기

김도현,박재현,김철기,차의영,Kim, Do-Hyeon,Park, Jae-Hyeon,Kim, Cheol-Ki,Cha, Eui-Young 한국정보통신학회 2007 한국정보통신학회논문지 Vol.11 No.10

문자 인식은 인공지능의 한 분야로써 자동화 시스템, 로봇, HCI 분야에서 그 응용성 이 증대되고 있는 첨단 기술이다. 본 논문에서는 숫자, 기호, 영어, 한글이 여러 가지 형태로 조합되어 사용될 수 있는 영역에서의 문자 인식을 위해 인식 문자 집합과 대표 문자를 도입하였다. 여러 가지 조합의 언어 집합에 따른 소규모 인식기를 계층적으로 조합하여 인식 결과의 정확성을 높이고 시간 비용을 줄일 수 있는 효율적인 인식기 구조를 제안하였다. 그리고 학습 성능이 우수한 Delta-bar-delta 알고리즘을 이용하여 개별 소규모 인식기를 학습한 다음 다양한 개별 문자를 대상으로 그 인식 성능을 살펴본 결과 99%의 인식률을 획득함으로써 혼용 언어 문자 인식의 효율성과 신뢰성을 증명하였다. The character recognition technique is one of the artificial intelligence and has been widely applied in the automated system robot HCI(Human Computer Interaction), etc. This paper introduces the character set and the representative character that can be used in the recognition of the mage ROI. The character codes in this ROI include the digit, symbol, English and Hereat etc. We proposed the efficient multi-classifier structure by combining the small-size classifiers hierarchically. Moreover, we generated each small-size classifiers by delta-bar-delta learning algorithm. We tested the performance with various kinds of images and achieved the accuracy of 99%. The proposed multi-classifier showed the efficiency and the reliability for the mixed character code set.

활주로안전구역 위험평가 개선모델 적용 연구

김도현,홍승범,Kim, Do-Hyun,Hong, Seung-Beom 한국항공운항학회 2015 한국항공운항학회지 Vol.23 No.2

The RSA is intended to prevent the following five types of events from becoming an accident: landing overruns, landing undershoots, landing veer-offs, takeoff overruns and takeoff veer-offs. The improved models are based on evidence from worldwide accidents and incidents that occurred during the past 27 years. The analysis utilizes historical data from the specific airport and allows the user to take into consideration specific operational conditions to which movements are subject, as well as the actual or planned RSA conditions in terms of dimensions, configuration, type of terrain, and boundaries defined by existing obstacles. This paper shows how to apply the improved models for Risk Assessment of Runway Safety Areas (Airport cooperative research program(ACRP) Report 50) into an airport and the outcome differences between the old models based on ACRP report 3-Analysis of aircraft overrun and undershoots for runway safety areas and the new models from ACRP report 50 in the specific airport.

특정 조건의 비행장에서 장애물제한규정 적용 사례연구

김도현,김웅이,Kim, DoHyun,Kim, Woong Yi 한국항공운항학회 2016 한국항공운항학회지 Vol.24 No.2

Obstacle defines all fixed and mobile objects, or parts thereof, that are located on an area intended for the surface movement of aircraft or extend above a defined surface intended to protect aircraft in flight or stand outside those defined surfaces and that have been assessed as being a hazard to air navigation. The airspace around airports are maintained free from obstacles so as to permit the intended aeroplane operations at the airports to be conducted safely and to prevent the airports from becoming unusable by the growth of obstacles around the airports. This is achieved by establishing a series of obstacle limitation surfaces or airspace imaginary surfaces that define the limits to which objects may project into the airspace. This is a case study that shows an application of obstacle limitation criteria, which must be maintained free from an critical obstacle, for specific conditions of two airports. For the purpose of the application, aeronautical studies/flight safety influence assessments were used to identify possible solutions and select a solution that is acceptable without degrading aviation safety.

수의과대학 반려동물병원의 프로그램 및 공간구성에 관한 연구 - 최근 10년 내에 준공 된 국내 수의과대학 동물병원 분석을 중심으로

김도현,Kim, Dohyeon 한국의료복지시설학회 2017 의료·복지 건축 Vol.23 No.3

Purpose: At the moment prevention and treatment of animal related diseases is becoming a social concern as the demand for animal increases. Furthermore, The design of the veterinary medical teaching hospital are even more complex because they have to accommodate medical program for animal and education and research program for students. However, there are a few experience and useful guidelines for the planning of the veterinary medical teaching hospital. So it is not easy for the regional hub universities to work out the proper plan for the construction of the veterinary medical teaching hospital for their own. This study has been started in order to provide basic informations for the planning of Korean veterinary medical teaching hospital. Methods: Interview to veterinarian, intern and employee of the veterinary medical teaching hospital and Field surveys to veterinary medical teaching hospital in Korea have been conducted for the data collection. The drawings of three universities of veterinary medical teaching hospital have been analysed and diagramed. Results: The result of this study can be summarized into three points. The first one is that the veterinary medical teaching hospital spaces are divided into five areas (ambulatory care, central medical care, hospitalization, education and research, operations and support) and each area is divided independently and connected properly. The second one is that the veterinary medical teaching hospital differs from hospital in the detailed space plan in the sense that the animal is a patient. The third one is that each hospital has different operating practices and programs according to local conditions Implications: It is meaningful as a basic source of veterinary medical teaching hospital design in the future.

빅 데이터를 활용한 코로나19 이전과 이후의 남성 패션에 대한 인식 비교

김도현,김정미,Kim, Do-Hyeon,Kim, Jeong-Mee 한국의상디자인학회 2022 한국의상디자인학회지 Vol.24 No.3

The purpose of this study is to compare and analyze the perception of men's fashion before and after the COVID-19 pandemic. TEXTOM allowed the collection of Big Data based on the term 'men's fashion'. As for the data collection periods, Jan. 1, 2018 to Dec. 31, 2019 was set as the pre-COVID-19 era, while Jan. 1, 2020 to Dec. 31, 2021 was set as the post-COVID-19 era. The top 50 words in terms of appearance frequency were extracted from the data. The extracted words were processed using network centrality analysis and CONCOR analysis using Ucinet 6. Research findings were as follows. 1) In the pre-COVID-19 era, the appearance frequency of 'men' was the highest, followed by 'fashion', 'men's fashion', 'brand', 'daily look', 'suit', and 'department store'. These words came up with a high TF-IDF values. Network centrality analysis discovered that 'men', 'fashion', 'men's fashion', 'brand', and 'suit' had a high level of connectivity with other words. CONCOR analysis showed four significant groups: 'fashion item and styles', 'fashion show', 'purchase', and 'collection'. 2) In the post-COVID-19 era, the appearance frequency of 'men' was the highest, followed by 'fashion', 'brand', 'men's fashion', 'discount', 'women', and 'luxury'. These words also displayed high TF-IDF values. Network centrality analysis found that 'fashion', 'men', 'brand', 'men's fashion', and 'discount' had a high level of connectivity with other words. CONCOR analysis showed four significant groups: 'fashion item and style', 'fashion show', 'purchase', and 'situation'. 3) Before the outbreak of the pandemic, men were interested in suits to wear to the office, daily look, and fashion shows in Milan and Paris. They often purchased menswear in multi-brand and open stores. However, they were more interested in sneakers, casual styles, and online fashion shows as social distancing and working from home became common. Most purchased menswear through online platforms.