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An Overview of Myocardial Bridging With a Focus on Multidetector CT Coronary Angiographic Findings
고성민 대한심장학회 2008 Korean Circulation Journal Vol.38 No.11
Myocardial bridging (MB) is a common anatomical variant rather than a congenital anomaly, and it is usually considered benign. It is generally confined to the mid-portion of the left anterior descending coronary artery. Atherosclerotic plaques are often located in the segment proximal to the bridged segment, although the tunneled segment is typically spared. Conventional coronary angiography is the gold standard for detection, but it is invasive and may not be sensitive enough to detect a thin bridge. The prevalence of MB reported in multidetector CT (MDCT) coronary angiographic series has ranged from 3.5% to 30.5% in patients with chest pain or with suspected or known coronary artery disease. Today, MDCT coronary angiography is an alternative noninvasive imaging tool that allows for easy and accurate evaluation of MB. Myocardial bridging (MB) is a common anatomical variant rather than a congenital anomaly, and it is usually considered benign. It is generally confined to the mid-portion of the left anterior descending coronary artery. Atherosclerotic plaques are often located in the segment proximal to the bridged segment, although the tunneled segment is typically spared. Conventional coronary angiography is the gold standard for detection, but it is invasive and may not be sensitive enough to detect a thin bridge. The prevalence of MB reported in multidetector CT (MDCT) coronary angiographic series has ranged from 3.5% to 30.5% in patients with chest pain or with suspected or known coronary artery disease. Today, MDCT coronary angiography is an alternative noninvasive imaging tool that allows for easy and accurate evaluation of MB.
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고성민,한정수,성용주 한국펄프·종이공학회 2023 펄프.종이기술 Vol.55 No.1
We investigated the effect of mechanical treatments on the defibration behavior of rice husk for determining the optimal condition for the production of the non-woody fibers. The investigation examined the behavior of rice husk defibration under different mechanical treatment methods, levels of solid consistency, and working temperatures. Two types of mechanical treatment methods including the traditional valley beater and the high speed grinder were applied for this study. Higher impact by high speed grinder generated more amount of fibers and fines, respectively than those by the valley beater. In the same mechanical treatment method, the higher solid consistency and the higher working temperature could promote more fiber generation. Consequently, this study showed the possibility of the effective production of non-woody cellulose fiber from rice husk by mild alkaline pretreatment and following optimal mechanical defibration condition. .
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고성민,윤영철,조광현,이양행,한일용,박경택,황윤호,전희재 대한흉부외과학회 2013 Journal of Chest Surgery (J Chest Surg) Vol.46 No.3
Background: Treatment for patent ductus arteriosus (PDA) in premature infants can consist of medical or surgical approaches. The appropriate therapeutic regimen remains contentious. This study evaluated the role of surgery in improving the survival of premature neonates weighing less than 1,500 g with PDA. Materials and Methods: From January 2008 to June 2011, 68 patients weighing less than 1,500 g with PDA were enrolled. The patients were divided into three groups: a group managed only by medical treatment (group I), a group requiring surgery after medical treatment (group II), and a group requiring primary surgical treatment (group III). Results: The rate of conversion to surgical methods due to failed medical treatment was 67.6% (25/37) in the patients with large PDA (≥2 mm in diameter). The number of patients who could be managed with medical treatment was nine which was only 20.5% (9/44) of the patients with large PDA. There was no surgery-related mortality. Group III displayed a statistically significantly low rate of development of bronchopulmonary dysplasia (BPD) (p=0.008). The mechanical ventilation time was significantly longer in group II (p=0.002). Conclusion: Medical treatment has a high failure rate in infants weighing less than 1,500 g with PDA exceeding 2.0 mm. Surgical closure following medical treatment requires a longer mechanical ventilation time and increases the incidence of BPD. Primary surgical closure of PDA exceeding 2.0 mm in the infants weighing less than 1,500 g should be considered to reduce mortality and long-term morbidity events including BPD.
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고성민,이병수,Go, Seong-Min,Lee, Byeong-Su 한국재료학회 1995 한국재료학회지 Vol.5 No.8
유기금속분해법(MOD, Metal Organic Decomposition)에 의하여 ITO 박막을 제조하고 SnO$_2$의 조성과 소성온도의 변화에 따른 박막의 특성변화를 고찰하였다. SnO$_2$의 양이 변하여도 ITO는 In$_2$O$_3$의 결정구조를 유지하고 있었으며, 이로부터 Sn이 In자리를 치환하여 고용체를 형성함을 알 수 있었다. SnO$_2$를 9wt.% 첨가 하였을때 비저항이 2.5$\times$$10^{-3}$$\Omega$-cm로 가장 낮은 값을 보였으며, 이는 타 연구자들의 결과치 보다 약 10배정도 큰 값이다. 이러한 비저항값의 차이는 작은 입경으로 인한 이동도의 감소 때문인 것으로 판단되었다. 투광도는 SnO$_2$의 첨가량 및 소성온도에 크게 의존하지 않았으며 가시영역에서 90% 이상을 보였다. 광흡수단으로부터 계산된 optical energy gap은 4.51-4.96eV 이었다. Thin films of Indium tin oxie (ITO) were prepared by the process of metal organic decomposition. Light transmittance and electrical transport properties of the films were studied with varying the firing temperature and SnO$_2$content. XRD study showed that tin substituted indium in the In$_2$O$_3$lattice. The resistivity had the minimum value of 2.5 ${\times}$ 10$\^$-3/$\Omega$-cm when the content of SnO$_2$was 9wt.%. This value was higher by a factor of 10 than the previously reported results. This difference was attributed to the low mobilities presumably caused by the fine grain size. The transmittance of ITO films in the visible range was over 90%, and the optical energy gap calculated from the absorption edge was in the range of 4.51 and 4.96eV.
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고성민,이정근,남창욱,김동훈 대한영상의학회 2008 대한영상의학회지 Vol.59 No.4
Purpose: We evaluated the diagnostic accuracy of a 64-slice multi-detector CT (MDCT) coronary angiography against a conventional coronary angiography (CCA) for the detection of significant stenosis (≥50% lumen diameter narrowing). Materials and Methods: Sixty-four patients underwent a MDCT and a subsequent CCA to evaluate the presence of atypical chest pain or suspected coronary artery disease (CAD). A MDCT angiography was performed using a 64-slice MDCT-scanner (Sensation 64, slice collimation 32×0.6 mm). The coronary artery segments were classified according to a 15-segment model. The sensitivity, specificity, and diagnostic accuracy of the 64-slice MDCT for the detection or exclusion of significant CAD were calculated on a per-segment and per-patient basis. Results: Fifty-nine of the 64 (92%) coronary CT angiograms were of diagnostic image quality with 93.5% (809 of 865) of the coronary segments assessable by CT angiography. One-hundred two (12.6%) segments showed significant stenosis by CCA. Stenosis of 50% or greater was detected by sensitivity, specificity, accuracy, positive predictive valve, and negative predictive value on a per segment basis (89%, 99%, 97%, 90%, and 98%, respectively) and a per-patient basis (96%, 69%, 90%, 92%, and 82%, respectively). Conclusion: The 64-slice MDCT coronary angiography demonstrated a high diagnostic accuracy for both the per-segment and per-patient analyses for this symptomatic patient group.
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자궁 경부에서 발생한 상피내 암종과 침윤성 암종의 간질 변화에 관한 병리조직학적 연구
고성민,노광을,이민전,김용임,이미자,전호종,서재홍 조선대학교 1993 The Medical Journal of Chosun University Vol.18 No.2
Connective tissue seems to be involved in malignancy by lytic processes as a crucial element in invasive growth. This looks relatively simple, but data have emerged that the stroma is not just a passive but rather an active participant. Recent advances in the borderland between cancer and connective tissue research have increasingly made it clear that the relationship between malignant tissue and its stroma is a very intricate one. The present study was performed in order to investigate the variety of stromal reactivity and alterations of basement membrane accompanying malignant growth and the distribution of Langerhans cells and T and B lymphocytes in cervical epithelium affected by intaepithelial neoplasia and invasive cervical carcinoma. The subjects in this were 14 cervicitis, 42 cervical intraepithelial neoplasia, 14 microinvasive cervical carcinoma and 14 invasive cervical carcinomas. A total of 84 formalin-fixed and paraffin-embedded specimens of normal, inflamed and neoplastic uterine cervix have been studied in order to correlate the epithelial changes with the expression of α-smooth muscle actin, S-100 protein, α_1-antichymotrypsin, lysozyme, LCA, CD20, UCHL1, OPD4, CD1, CD4, CD8, CD68 and typeⅣ collagen in stroma. The results of immunohistochemical and electron microscopical examinations yield virtually identical findings 1) The number of α-smooth muscle actin positive cells and the intensity of stain were related to the increasing grading of cervical intraepithelial neoplasia and invasive cervical carcinoma. 2) Normal cervix and cervical intraepithelial neoplasia grade Ⅰ and Ⅱ showed continuous basement membrane but invasive cervical carcinoma showed highly variable basement membrane deposition ranging from continuous to almost completely absent. 3) The cervical intraepithelial neoplasia Ⅲ and invasive cervical carcinoma showed an increase in spindle shaped Langerhans cells associated with increased numbers of stroma and intraepithelial lymphoid cells. The evaluation of collagen Ⅳ in basement membrane, S-100 protein and CD1 in Langerhans cells and α-smooth muscle actin in stromal cells of the uterine cervix may be an useful adjunct to diagnostic criteria of cervical intraepithrlial neoplasia and invasive cervical carcinoma, and may help understanding of the mechanisms of mesenchymal epithelial interactions during neoplasia.
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