Sub-90nm급 Logic 소자에 대한 기생 저항 성분 추출의 연구

이준하,이흥주,이주율 호서대학교 반도체제조장비국산화연구센터 2003 학술대회 자료집 Vol.2003 No.1

sub-90nm급 high speed 소자를 위해서는 extension영역의 shallow junction 과 sheet 저항의 감소가 필수적이다. 일반적으로 기생저항은 channel저항의 약 10∼20%정도를 차지하도록 제작되므로, 이를 최소화 하여 optimize하기 위해서는 기생저항에 대한 성분 분리와 이들이 가지는 저항값에 대항 정략적 계산이 이루어져야 한다. 이에 본 논문은 calibration된 TCAD simulation을 통해 90nm급 Tr.에서 각 영역의 저항성분을 계산, 평사하는 방법으로 제시한다. 이 결과, 특히, extention영역의 표면-accumulation부분이 가장 개선이 있어야 할 부분으로 분석되었으며, 이 저항은 gate하부에 존재하는 extension으로부터 발생되는 측면 doping의 tail영역으로 인해 영성되는 것으로,doping의 abruptness가 가장 중요한 factor인 것으로 판단된다.

OLETF 당뇨쥐에서 당뇨시기에 따른 방광의 기능적, 형태학적및 분자생물학적 변화

이준하,서홍진,조혁진,이용석,김현우,김상훈,김세웅,황태곤,이선주,이지열 대한비뇨의학회 2009 Investigative and Clinical Urology Vol.50 No.4

Purpose: Our study was undertaken to investigate changes in the bladder according to duration of diabetes mellitus in the Otsuka Long Evans Tokushima Fatty (OLETF) rat model, which is similar to type 2 diabetes. Materials and Methods: OLETF rats (n=14) and Long Evans Tokushima Otsuka (LETO, n=14) rats were used. LETO is a normal control of OLETF. The animals were assigned to 4 groups: L-40 group, LETO rats 40 weeks after birth (n=7); O-40 group, OLETF rats 40 weeks after birth (n=7); L-60 group, LETO rats 60 weeks after birth (n=7); and O-60 group, OLETF rats 60 weeks after birth (n=7). At 40 weeks or 60 weeks after birth, blood glucose, cystometry, bladder weight, detrusor contractility, and mRNA expression of nerve growth factor (NGF) were assessed. Results: Cystometry showed that diabetic bladders had increased compliance compared with the control groups at 40 and 60 weeks, and the O-60 group had greater compliance than the O-40 group. Contractile responses to electrical stimulation, bethanecol (250μM), and ATP (10 mM) were decreased in the experimental groups compared with the control groups at 40 and 60 weeks, and the O-60 group had a lower contractile response than the O-40 group. The mRNA expression of NGF was decreased in the experimental groups compared with the control groups, and the O-60 group had lower expression than the O-40 group. Changes in NGF were identified through immunohistochemical staining. Conclusions: The degree of diabetic cystopathy in OLETF rats was changed by duration of type 2 diabetes mellitus. Our results showed that the changes in the bladder in type 2 diabetes mellitus can be identified through a new rat model.

실내 저농도 VOCs 제어를 위한 플라즈마/광촉매 하이브리드 시스템 활용에 관한 연구

이준하,조영민,김상범 한국대기환경학회 2022 한국대기환경학회 학술대회논문집 Vol.2022 No.10

OLETF 당뇨쥐에서 당뇨시기에 따른 방광의 기능적, 형태학적 및 분자생물학적 변화 /

이준하,서홍진,조혁진,이용석,김현우,김상훈,김세웅,황태곤,이선주,이지열 大韓泌尿器科學會 2009 Korean Journal of Urology Vol.50 No.4

원자간력 현미경 탄소 나노튜브 팁을 이용한 플러렌 나노 구조물 제작에 관한 분자동역학 시뮬레이션

이준하,이홍주 한국전기전자재료학회 2004 전기전자재료학회논문지 Vol.17 No.8

This paper shows that carbon nanotubes can be applied to a nanopipette. Nano space in atomic force microscope multi-wall carbon nanotube tips is filled with molecules and atoms with charges and then, the tips can be applied to nanopipette when the encapsulated media flow off under applying electrostatic forces. Since the nano space inside the tips can be refilled, the tips can be permanently used in ideal conditions of no chemical reaction and no mechanical deformation. Molecular dynamics simulations for nanopipette applications demonstrated the possibility of nano-lithography or single-metallofullerene-transistor array fabrication.

Galleria mellonella 6-Tox Gene, Putative Immune Related Molecule in Lepidoptera

이준하,박승미,채권석,이인희 한국잠사학회 2010 International Journal of Industrial Entomology Vol.21 No.1

We have characterized full-length cDNA encoding Gall-6-tox protein, which was cloned from the fat body of the immunized Galleria mellonella larvae. The cloned cDNA of Gall-6-tox consists of 1301 nucleotides and contained an open reading frame of 891 nucleotides corresponding to a protein of 296 residues that includes a putative 16-residue signal sequence and a 280-residue mature peptide with a calculated mass of 30,707.73 Da. The deduced mature peptide contains conserved tandem repeats of six cysteine-stabilized alpha beta (Cs ) motifs, which was detected in scorpion toxins and insect defensins. In the sequence homology search, mature Gall-6-tox showed 34% and 28% amino acid sequence homology with Bomb-6-tox from Bombyx mori and Spod-11-tox from Spodoptera frugiperda, respectively. Gall-6-tox orthologs were only found in Lepidopteran species, indicating that this new immune-related gene family is specific to this insect order. RT-PCR analysis revealed that Gall-6-tox was expressed primarily in the larval fat bodies, hemocytes,and midgut against invading bacteria into hemocoel. Moreover, the expression time course of Gall-6-tox was examined up to 24 h in the fat bodies and midgut after injection of E. coli. Altogether, these results suggest that Gall-6-tox is derived from defensins and Gall-6-tox may play a critical role in Lepidoptera immune system.

전자파에 노출된 생체두부의 전기생리적 변화의 측정에 관한 연구

이준하,신현진,이상학,유동수,이무영,김성규 한국의학물리학회 1994 의학물리 Vol.5 No.2

전자파가 일상생활에서 생체에 많은 영향을 미치는 것으로 알려져 있으나 실제로 그 영향을 정성, 정량적으로 규명하는 것은 용이하지 않다. 본 연구에서는 생체의 전기적 신호를 이용하여 2.45GHz의 전자파에 노출시킨 토끼의 두부에 대한 영향을 측정하는 방법을 검토하였다. 연구결과, 두부모델의 손상정도는 뇌전위의 연속적인 FFT 신호처리에서 뇌활성도 저하를 관찰할 수 있었으며, 특정 주파수와 강도(최소허용전력과 치사전력)에 대한 기준 설정에 필요한 요소를 제시할 수 있었다. Electromagnetic wave may induce effect and damage on the bio-body, either by electric fields of magnetic fields. We measure electrophysiological changs in rabbit's brain exposed to 2.45GHz micro wave(power density 40mW/cm$^2$) which distance 30cm from the source. In order to process the bio-electrical signal (EEG), used pre-amplifier module with self-made and Digtal analyzer computer system. Spectal analysis of the EEG showed variable power in the frequency range(1~30Hz) through each exposure time(10min, 20min, 30min) before and after. In effectively measured by the bio-electrical signal processing and can found threshold of minmal permissible exposure and lethal exposure.

다채널 대용량 충방전기 모듈 개발에 대한 연구

이준하 한국반도체디스플레이기술학회 2016 반도체디스플레이기술학회지 Vol.15 No.2

This study was developed through the secondary battery module charging/discharger possible utilization in the production process equipment circuit. The developed module is ensuring construction of efficient and productive charging and discharger through this research a limit on the yield and the price of existing single -channel charge and discharger circuit as a 5V 70A grade secondary battery Formation charge and discharger for up to 1 board 4 channels. In order to improve the sensing accuracy, through a robust differential amplifier circuit described using 16bit Analog-Digital Converter and noise was secured 16bit resolution sensing. The configuration also made demands for property Rise / Fall Time. Data Acquisition, discharge efficiency and also to fit the sink circuit temperature level for mass production.

원위 요골 골절 환자의 수술 후 예방적 항생제 사용기간에 따른 감염률 비교

이준하,이요한,조용길,강상윤,배기정 대한수부외과학회 2021 대한수부외과학회지 Vol.26 No.4

Purpose: In general orthopedic surgery, the use of prophylactic antibiotics to prevent infection is recommended to be administered within 24 hours. However, there was no analysis on the incidence of surgical site infection according to the duration of use of prophylactic antibiotics for upper extremity fractures. This study aims to derive the appropriate prophylactic antibiotic using time by analyzing the incidence of infection according to the time of prophylactic antibiotic use in distal radius fractures. Methods: We retrospectively analyzed patients who used prophylactic antibiotics among patients who underwent open reduction and internal fixation for distal radius fractures from April 2018 to May 2021. The time of use of prophylactic antibiotics was classified into the 1-day group used, from 1 hour before surgery to 24 hours after the first administration, and the long-term group, continuously administered until discharge after surgery. Demographic characteristics, infection rate, C-reactive protein, risk factors for surgical site infection, and bone union were compared between the two groups. Results: A total of 168 patients were included in the study, 73 in the 1-day group and 95 in the long-term group. Superficial infection occurred in seven patients in the 1-day group and nine in the long-term group, and there was no statistically significant difference in the incidence rates of the two groups (p=0.980). Conclusion: The use of prophylactic antibiotics for 24 hours does not show a significant increase in the infection rate compared to the case of continuous use during open reduction and internal fixation of distal radius fractures. 목적: 일반 정형외과 수술에서 수술부위감염을 방지하기 위한 예방적 항생제는 24시간 이내로 투여하는 것을 권장하고 있다. 하지만 상지의 골절에 대하여 예방적 항생제의 사용 시간에 따른 수술부위감염 발생률에 대한 분석은 없었다. 본 연구는 원위 요골 골절에서 예방적 항생제 사용시간에 따른 감염 발생률을 분석하여 적절한 예방적 항생제 사용시간을 도출하고자 한다. 방법: 2018년 4월부터 2021년 5월까지 원위 요골 골절로 관혈적 정복술 및 내고정술을 받은 환자들 중 예방적 항생제를 사용한 환자들을 후향적으로 분석하였다. 예방적 항생제의 사용시간은 수술 1시간 전부터 첫 투여 후 24시간까지만 사용한 하루사용군과 수술 후 퇴원 시까지 계속해서 투여한 장기사용군으로 분류하였다. 두 군 간의 인구학적 특성, 감염률, C-반응 단백질, 수술부위감염의 위험인자 유무, 골 유합 여부를 비교하였다. 결과: 해당 기간 동안 총 168명의 환자가 연구 대상에 포함되었으며 하루사용군 73명, 장기사용군 95명이었다. 하루사용군 7명, 장기사용군 9명이 표재성 감염이 발생하였으며 두 군의 발생률에서 통계적 유의성은 없었다(p=0.980). 결론: 원위 요골 골절의 관혈적 정복술 및 내고정술 시 예방적 항생제의 24시간 사용은 그 이상 지속 사용하는 경우와 비교해 감염률의 유의한 증가를 보이지 않는다

터널링 메커니즘을 이용한 메모리 소자 연구

이준하,Lee Jun-Ha 한국반도체디스플레이기술학회 2006 반도체디스플레이기술학회지 Vol.5 No.1

This paper presents of a new type of memory cell that could potentially replace both DRAM and flash memory. The proposed device cell operates by sensing the state of about 1,000 electrons trapped between unique insulating barriers in the channel region of the upper transistor. These electrons are controlled by a side gate on the transistor, and their state in turn controls the gate of the larger transistor, providing signal gain within the memory cell. It becomes faster and more reliable memory with lower operation voltage. Moreover, the use of a multiple tunnel junction (MTJ) fur the vertical transistor can significantly improve the data retention and operation speed.