Original Articles : Clinical significance of occult hepatitis B virus infection in chronic hepatitis C patients

( Jae Young Jang ),( Soung Won Jeong ),( Sung Ran Cheon1 ),( Sae Hwan Lee1 ),( Sang Gyune Kim ),( Young Koog Cheon ),( Young Seok Kim1 ),( Young Deok Cho1 ),( Hong Soo Kim ),( So Young Jin ),( Yun Soo 대한간학회 2011 Clinical and Molecular Hepatology(대한간학회지) Vol.17 No.3

Background/Aims: We investigated the frequency of occult hepatitis B virus (HBV) infection in anti-hepatitis C virus (HCV)-positive individuals and the effects of occult HBV infection on the severity of liver disease. Methods: Seventy-one hepatitis B virus surface-antigen (HBsAg)-negative patients were divided according to their HBV serological status into groups A (anti-HBc positive, anti-HBs negative; n=18), B (anti-HBc positive, anti-HBs positive; n=34), and C (anti-HBc negative, anti-HBs positive/negative; n=19), and by anti-HCV positivity (anti-HCV positive; n=32 vs. anti-HCV negative; n=39). Liver biopsy samples were taken, and HBV DNA was quantified by real-time PCR. Results: Intrahepatic HBV DNA was detected in 32.4% (23/71) of the entire cohort, and HBV DNA levels were invariably low in the different groups. Occult HBV infection was detected more frequently in the anti-HBc-positive patients. Intrahepatic HBV DNA was detected in 28.1% (9/32) of the anti-HCV-positive and 35.9% (14/39) of the anti-HCV-negative subjects. The HCV genotype did not affect the detection rate of intrahepatic HBV DNA. In anti-HCV-positive cases, occult HBV infection did not affect liver disease severity. Conclusions: Low levels of intrahepatic HBV DNA were detected frequently in both HBsAg-negative and anti-HCV-positive cases. However, the frequency of occult HBV infection was not affected by the presence of hepatitis C, and occult HBV infection did not have a significant effect on the disease severity of hepatitis C. (Korean J Hepatol 2011;17:206-212)

전통누룩 진균류를 이용한 입국의 제조 및 입국곰팡이의 동정

김재호 ( Jae Ho Kim ),권영희 ( Young Hee Kwon ),이애란 ( Ae Ran Lee ),김혜련 ( Hye Ryun Kim ),안병학 ( Byung Hak Ahn ) 한국균학회 2012 韓國菌學會誌 Vol.40 No.4

다양한 향미를 가진 막걸리의 개발을 위해 전통누룩으로부터 분리한 곰팡이로 입국을 제조한 후 품질특성을 분석하여 입국의 규격에 적합하며 이취가 없고 관능이 우수한 9균주를 입국 제조용 우수균주로 최종 선발하였다. 선발된 균주는 Aspergillus oryzae(C1-5-2-2, C20-7-3, CN1.3.1-4, CN16.19.1-1, N152-1, N220-1), Mycocladus corymbiferus (N162-2), Rhizopus oryzae(N20), Lichtheimia corymbifera (N21)로 동정되었으며, 제조한 입국의 산도는 5.0~6.8, 당화력은 128~241sp이었다. Various koji were prepared by fungi isolated from traditional nuruk and their quality characteristics were investigated. Acidity and saccharification power of their koji were ranged in 5.0~6.8 and 128sp~241sp. Nine fungi which were showed good quality and sensory evaluation were identified by analysis of their nucleotide sequences with PCR-amplified 18S rDNA internal transcribed spacer-1(ITS-1) and ITS-4 genes. Among them, six strains were identified as Aspergillus oryzae and the other strains were identified as Mycocladus corymbiferus, Rhizopus oryzae, Lichtheimia corymbifera.

한약에 의해 유발된 급성 간질성 신염 2례

김덕윤,박동건,김응석,강영모,양창헌,이정호,이동철,이영현,김정란 동국대학교 경주대학 1996 東國論集 Vol.15 No.-

간질성 신염은 신장의 간질을 선택적으로 침범하는 염증성 질환으로 여러가지 원인에 의해 유발되며, 이 중 약물에 의한 경우는 각종 항생제, 비스테로이드성 진통제, 항경련제, 이뇨제, 면역억제제등에 의한 증례들이 보고되고 있다. 현재 각종 질환-특히 만성질환-의 치료에서 한약이 차지하는 비중이 적지 않으나, 그 각각의 성분들이 유발할 수 있는 부작용들에 대한 연구는 거의 없는 실정이다. 저자들은 관절염 치료를 위해 중국산 한약을 복용한 후 복통, 피로감 및 육안적 혈뇨를 주소로 내원한 두 환자에서, 단백뇨와 신기능 장애를 보여 시행한 신조직 생검상 급성 간질성 신염에 합당한 병리학적 소견을 보이고, 한약 복용 중지 후 급속한 회복을 보여, 한약에 의해 유발된 것으로 사료되는 급성 간질성 신염 2예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Acute interstitial nephritis is a disease characterized by renal interstitial inflammatory cell infiltration and acute renal functional deterioration. This is caused mainly by antibiotics, NSAID and diuretics such as thiazide, but cases induced by herb medication are rare. We experienced two cases of acute interstitial nephritis after treatment with herb medication. One 71-year-old female patient and the other 60-year-old female were admitted to the hospital because of general weakness and gross hematuria. Microscopic hematuria, pyuria, and proteinuria were presented. After definitive diagnosis with a renal biopsy, we noted rapid recovery of renal function by drug withdrawal and steroid therapy. We report these cases with a review of the referenced literatures. Key Words : Herb medication, Acute Interstitial nephritis.

중학생의 건강행위에 영향을 미치는 결정요소

이영란,소희영 충남대학교 의과대학 지역사회의학연구소 1996 충남의대잡지 Vol.23 No.1

The study aimed to verify The Interaction Model of Client Health Behavior by Cox in order to extend the understanding for the health behavior of middle school students. The survey was conducted to the second-grade students of two middle schools in Dae Chun Metropolitan City by questionnaire from July 5 to 15, 1995. Total 660 students responded the research tool after the explanation of nurse teacher. A demographic questionaire was developed by researcher. Health Perception was measured by Ware's scale, Health self-determinism index for children was used to measure intrinsic motivation. Self-esteem was measured by the Harter's self perception profile for children. Health beha vior was measured by Ki's health behavior scale. Collected data was processed through the frequency, t-test, ANOVA and regression test of SAS program. The findings obtained were as follows; 1. Statistically meaningful difference was found about the health behavior acccrding to gender(t=4.25, p<.001). Boy students showed more health behavior than girl students. 2. As to boy students, the determinants of the health behavior were father's health, student's health and father's education among client peculiarity elements, which appeared to have influence on the intrinsic motivation, health perception and self-esteem of mediating variables. Among the mediating variables health perception was the determinants of the health behavior. 3. As to girl students, the determinants of the health behavior were father's health, student's health, father's education and mother's education among client peculiarity elements, which appeared to have influence on the intrinsic motivation, health perception and self-esteem of the mediating variables. Among the mediating variables, the intrinsic motivation and health perception were the determinants of the health behavior. 4. In this model, the determinants of boy students explained the health tehavior by 6%, and the ones of girl students by 11.6%. From the above findings, the variables constituting the health behavior appeared to be of very low utility. More study seemed to be needed to verify the validity of the IMCHB. It's not possible for nurse teacher to directly mediate the populational sociological variables in regards of student peculiarity. But continuous health education by nurse teacher would improve student's intrinsic motivation, health recognition and self-esteem and guide the desirable health behavior. Besides, cooperation with community resources would be helpful to develop a program improving parent's health, and finally to improve the health behavior of middle school students.

出雲神話一考

李永蘭 대구효성가톨릭대학교 외국어문학연구소 1990 語文學硏究 Vol.3 No.-

중학생의 아토피피부염 유무에 따른 생활양식 비교 연구

이화자,조영란,박지은 韓國學校保健學會 2005 韓國學校保健學會誌 Vol.18 No.2

Purpose:This study compared lifestyles of middle school students with and without atopic dermatitis in order to obtain the baseline information for health education. Methods:This study involved 256 students from 20 middle schools in Busan who suffered from atopic dermatitis and 231 students from 2 middle schools in Busan who did not have atopic dermatitis. Results:Students with atopic dermatitis had a lower family income (塔=16.99, p<.001) and were more likely to come from a nuclear family (塔=10.28, p<.001) than control students. 98% of the students with atopic dermatitis had several skin symptoms. 78.5% of students with atopic dermatitis reported experiencing difficulties in their daily because of their condition. Students with atopic dermatitis took shorter baths and used soap less frequently than the students in the control group. The students with atopic dermatitis cleaned their houses and bedclothes more often than normal students in an attempt to remove cockroaches and house-dust mites. Students with atopic dermatitis also ate fast and instant foods more often than normal students. Conclusions:Some lifestyle differences exist between students with and without atopic dermatitis. Therefore, education and guidance may be important to promote good health and improve lifestyle quality.

《竹取物語》성립에 관한 일고찰

이영란 효성여자대학교 한국전통문화연구소 1996 韓國傳統文化硏究 Vol.11 No.-

『竹取物語』の內容の中で, 特に翁による主人公かぐや姬の發見の部分と, 後半部の月の世界への昇天を語る部分は, 『萬葉集』『風土記』『今昔物語集』その他に, 類似する話として傳ぇられている. これはすなわちこの物語の素材が全篇にわたって古代に傳ぇられていた多くの民間說話をはじめ, いろいろの多樣な傳承屑話に基づいているのを語っている. それで本考では, この物語の中核をなす素材が具體的にどんなものであるかを考察し, それが 作品の中ではどうふうに取り扱われているのかを調べることで, この物語の主題性について考えてみることにしたい. 『竹取物語』は 素材の面から見ると大きく羽衣傳承と難題求婚譚の二つの流れをなしているが, いずれにしろ古代傳承それ自體がそのまま作品に なったのではなく, 傳えられていろいろの素材を消化し, 創作されたものと認めなければならい要素が多いにある. つまり この作品は日本古代に傳えられていた民間素材をもとにして, それが羽衣傳承が創作のヒントとなり 作品の現實性を加える效果も出す實在人物名を使つた難題求始譚を混ぜて出來あがつた假名散文作品である.

四分法과 K.D.C.의 比較

이영란 明知大學校 圖書館學科 1987 圖書館學論集 Vol.1 No.1

보건교사와 일반교사의 성교육 수업실태, 자료 활용도 및 문제해결 요구도 비교

이정란,안숙희,김영혜,조규영 韓國學校保健學會 2004 韓國學校保健學會誌 Vol.17 No.2

Purpose : This descriptive study was conducted to compare the teaching status, utilization of the teaching materials, and the need to solve matters of sex education between the school health educators and teachers working in an elementary school in Busan. Method : 182 school health educators and 125 teachers participated in the research. Data was collected using a self-administered questionnaire, and analyzed by frequency and x2 .test using the SPSS WIN 10.0 Program. Results: While school health educators carried out most of the sex education in the extra curriculum and physical education class, teachers did in the regular curriculum and physical education class. Regarding the utilization of the teaching materials on sex education, although the majority of school health educators used the teacher's manual, only a few teachers used it. Most of the school health educators used the ICT teaching materials while only half of the teachers did. Regarding the methods to solve matters on sex education, school health educators responded that a sex-related subject should be combined with a health subject, and an independent sex-related subject was necessary. The teachers, however, responded that it was necessary to secure enough time for sex education, the sex-related subject combined with a health subject was necessary, and there is a need to designate a sex educator. Conclusion: School health educators utilized more teaching materials for sex education and suggested more active methods to solve matters related to sex education. Therefore, school health educators should be more active as sex educators, and the subject of sex education should be adopted as a regular course.

유치원 건축물 파사드 유형별 선호도에 관한 연구 : 유아의 시각적 선호도 입장에서

이청웅,노영란,박성진 朝鮮大學校 建設技術硏究所 2007 建設技術硏究 Vol.27 No.1

The infancy is the rapidest period of physical and psychical growth and also the sensitive period of the environmental influence, so the nursery school building must be considered like this way that could be satisfied with the various factors which are considered the aesthetic of the infant as a main user. It's still insufficient state, the existing studies about the formation of the nursery school building. According to the existing studies about the formation of the general building, the most of them are based on a visual analysis and also we can see this kind of analysis of the external shape is just a superficial analysis. So the purpose of this study is to classify the type of the facade to satisfy with the demand as the aesthetic sense of the infant by the visual and perceptual dimension of the infant as the nursery school's effective user and to analogize the direction of the 입면형상expression that collecting the demand as the aesthetic sense of the infant and the aesthetic sense of an architect who plan the nursery school and the general people as the nursery school building is built.