제주 성상 S/S MTr #1 행원 풍력단지 전압해석

김상준(Sang-Jun Kim),조민호(Min-Ho Cho),윤기갑(Gi-Gab Yoon),장상옥(Sang-Ok Jang),안정식(Jeong-Shik Ahn) 대한전기학회 2003 대한전기학회 학술대회 논문집 Vol.2003 No.11

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

Paraquat 중독환자의 초기검사로서 sodium dithionite를 이용한 소변내 paraquat검출의 임상적 의의

윤갑준,임경수,이진웅,김영식,이부수,박덕우,김선만,이강현,황성오,안무업 대한응급의학회 1995 대한응급의학회지 Vol.6 No.1

Background : Mortality from paraquat intoxication depends upon plasma paraquat concentration. To know the severity of paraquat intoxication is important for directing therapeutic modality and predicting prognosis. Sodium dithionite test for urinary paraquat provides an easy and simple method to determine the severity of paraquat intoxication in emergency department. purpose : To determine whether the result urinary paraquat test by sodium dithionite can predict outcome in patients with paraquat intoxication in emergency department. Subjects : 48 patients(male 31, female 17, mean age 37 years) who had exposure to paraquat and presented within 24 hours after exposure. Result : Thirty five patients were positive in paraquat urine test and thirteen patients were negative. Clinical manifestations were more severe in positive patients than in negatives. Complication was much more in positives than in negatives. 28 of 35 patients(80%) in positives and 2 of 13 patients(15%) in negatives died. Conclusion : Positive test for urinary paraquat is associated with high mortality and morbidity from paraquat intoxication, and qualitative test for urinary paraquat by sodium dithionite is an useful method to determine the severity of paraquat intoxication in emergency department.

[TEACOOH]-Montmorillonite 층간화합물의 형성 및 층 내에서의 고분자화 반응

윤도우,조성준 배재대학교 공학연구소 2005 공학논문집 Vol.7 No.1

Na-Montmorillonite와 10-Carboxy-n-decyltriethylammonium bromide (유기 양이온) 사이의 양이온 교환반응에 의해 얻어진 [TEACOOH]-Montmorillonite 층간화합물을 유기 단분자인 ε-caprolactone을 반응시켜 [TEACOOH]-ε-caprolactone-Montmorillonite 층간화합물을 형성하였다. 이렇게 얻어진 [TEACOOH]-ε-caprolactone-Montmorillonite 층간화합물을 220oC의 온도 하에서 48시간 동안 가열하여 고분자화시켜 무기물질인 몬모릴로나이트와 유기 고분자인 폴리카프로락톤이 화학적으로 결합된 몬모릴로나이트/폴리카프로락톤 나노복합재료를 제조하였다. 고분자화반응을 수행한 후 얻어진 시료를 메탄올을 이용하여 추출한 뒤 고진공 하에 65oC로 24 시간 동안 건조시킨 후에 얻은 층간거리 값으로는 34.24 Å이 얻어졌다. [TEACOOH]-Montmorillonite intercalations complex obtained from Na-Montmorillonite and 10-Carboxy-n-decyldimethylethylammonium bromide(organic cation) was reacted with the monomer(ε-caprolactone) to achieve the [TEACOOH]-ε-caprolactone-Montmorillonite intercalations complex. From this intercalations complex Montmorillonite/Polycaprolactone Nanocomposite in which montmorillonite(inorganic material) is chemically linked with the polycaprolactone(organic polymer) was formed at 220oC for 48 h. The basal spacing for the sample obtained after polymerization, extraction with methanol and dried at 65oC in high vacuum for 24 h was 50.7 Å.

유도선수들의 개인별 특성에 따른 성취동기에 미치는 영향 : mainly university students

윤익선,김진표,권성준 龍仁大學校 武道硏究所 2002 武道硏究所誌 Vol.13 No.1

This investigation used questionnaire which amended and made up for TSMI(Taikyo Sport Motivation Inventory) to verify what effect judo champions personal trait has on accomplishment motive. The subject of the study was 406 men, women judo champion's in Seoul and Kyung-Ki province. The personal trait which is an independent variation was set up as sexual distinction, grade, athlete career, economic standard, record of winning a prize and weight. According to this, the dependent variable for accomplishment motive to find out about accomplishment motive was foxed as competition, ambition, effort and self-confidence and the result of the research is followed as below. Firstly, there seemed to exist a significant difference in competition(p<.001), standard of ambition(p<.006) and self confidence(p.006) in accomplishment motive according to sexual distinction. Secondly, a significant difference in standard of ambition(p<.001) existed among the dependent variable of accomplishment motive according to grade. Result of Scheffe's pre-verification was that significant difference seemed to exist in 4th grade with the 1st and 3rd grade. Thirdly, all of the dependent variable; competition(p<.001), standard of ambition(p<.001), effort(p<.003) and self confidence(p.006) showed significant difference in accomplishment motive according to athlete's career. Scheffe's pre-verification showed that significant difference in competition existed in between 5-8 years and 8-10 years, and significant difference in standard of ambition in between 3-5 years and 8-10 years and also 3-5 years and 5-8년 and over 10 years group existed. Also significant difference in effort showed in 5-8 years and 8-10 years. Fourthly, the accomplishment motive according to the economic levels showed significant difference only in standard of ambition(p<.05) which is a dependent variable. Fifthly, The accomplishment motive according to the career of winning a prize showed a significant difference in competition(p<.01), ambition(p<.01) and effort(p<.05) among the dependent variable, and also Scheffe's pre-verification showed a significant difference in more than 7 times, less than 3times and less than 7 times in ambition. Sixthly, the accomplishment motive according to weight showed a significant difference in competition(p<.001) and effort(p<.05) among the dependent variable, and Scheffe's pre-verification showed significant difference in middle weight class with the lightweight and middle lightweight class in competition.

무통성 혈뇨를 주소로 내원한 58세 남자환자

尹常敏,金佐濬 대한의사협회 1999 대한의사협회지 Vol.42 No.12

단일 치근을 가진 하악 제1유구치

윤상일,최형준,김성오,이제호,손흥규 大韓小兒齒科學會 2004 大韓小兒齒科學會誌 Vol.31 No.4

본 증례에서는 단일 치근을 가진 하악 제1유구치에 대해 서술하고자 한다. 5세 남아의 하악 제1유구치는 방사선 사진 검사결과 양측성으로 분명한 단일치근을 가진 것으로 나타났다. 보통 상악 구치는 3개의 치근을, 하악 구치는 2개의 치근을 가지나, 치아의 발육시기도중 Hertwig상피근초가 제 시기에 적절히 함입되지 못하면 치근이 서로 나뉘지 못하여 치근의 융합이 발생될 수 있다. 융합된 치근을 가진 구치는 정상적인 구치보다 불리한 치관-치근 비율을 가질 뿐 아니라, 여러 보고에 의하면 융합된 치근을 가진 사람은 다수 치아의 선천적 결손이나, 상악 전치에서 치내치가 발현될 확률이 높아 예방적 치과 치료가 필요할 수 있다. 그리고, 외배엽이형성증, 합지증, 만지증, 청색공막증과 같은 전신 질환과 연관되어 나타날 수도 있다고 한다. 치근융합은 유전적으로 상염색체 열성 유전을 따른다고 밝혀진 바 있다. 현재까지 단일 치근을 가진 구치는 대부분 영구 구치에서 많이 보고된 바 있지만, 유구치에서는 거의 보고된 바가 없기에 이에 보고하는 바이다. In this case, we would like to discuss about the single rooted deciduous mandibular first molar. The deciduous mandibular molar of a five years old boy was shown to have a single root, bilaterally. Ordinarily, the maxilary molars have three roots and the mandibular molars have two roots. However, when the hertwig's epithelial root sheath do not invaginate properly during tooth development, root fusion can occur from the absence of root separation. Molars with fused roots not only have unfavorable crown to root ratio, but also according to many reports, have higher probability of having multiple congenitally missing teeth or dens invaginatus in the maxillary incisors, consequently requiring preventive dental treatment. In addition, disorders such as ectodermal dysplasia, syndactyly, clinodactyly, bluish sclera can also be related to this condition. Root fusion is known to be of autosomal recessive inheritance. Up to date, single rooted molars have been reported several times in permanent dentitions but hardly in deciduous dentition, which is the motive for this paper.

지역사회교육을 위한 농촌폐교시설의 활용방안에 관한 연구

윤준상,이창식 公州大學校 産業開發硏究所 1998 産業開發硏究 Vol.6 No.-

Because of reduction of population in rural area, primary schools in that area are exposed to many problems and the environment of education of rural area has been deterrioration. In this situation, many cases of mergeer and abolition(M&A) of primary school in rural area were reported. The aims of this study were to define the concept of Community Education and to review, factors and method, the situation and problems of M&A and to suggest the policy direction to the M&A in rural area for the Community Education. This study was carried out through review of literature an statistical data collected from varioous sources. The major findings of this study were as follows: 1) The M&A of primary school is inevitable for change of placement standard to primary school and qualitative improvement of environment of education in rural area. 2) By the mobility of modern industrial society and the inequality between urban area and rural area in developing stage, necessity of M&A is increasing. 3) In this consequence, the number of abolished school is also increasing, and the relevant plan of utilization of facilities of abolished school is needed. Based on the results of the study, it was recommended that the M&A of primary school of rural area be changed to the Community Education Center. And comprehensive policy community education directions which include educational inevestment, public relation and gross social welfaree are to be formed.

地域開發政策에 대한 住民의 集團行動參與의 理論的 論議

尹畯相,申尹澈 公州大學校 地域開發硏究所 1994 地域開發硏究論叢 Vol.2 No.1

급성 호흡곤란 증후군으로 발현된 폐결핵 1례

윤여준,박성우,이준혁,장안수,박춘식 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

Pulmonary tuberculosis as a cause of the acute respiratory distress syndrome is quite rare. The diagnosis of acute respiratory distress syndrome due to pulmonary tuberculosis is difficult because of the diversity of radiological patterns. The ability to identify patients at risk for the acute respiratory distress syndrome is important if therapies are to be developed to prevent the disorder. We experienced a young female compliants with mild fever, dyspnea who diagnosed pulmonary tuberculosis 1 months ago. She stoped anti-tuberculosis medication 2 day because confirmation of drug fever and after then sudden aggravated dyspnea. The clinical course of this case is similar with presentaion of ARDS. We started antituberculosis medication with steroid, which result in good prognosis.