카드뮴 및 청국장 첨가식이가 흰쥐의 생육과 체내 카드뮴 분포에 미치는 영향

주현규,강경원,사동민 선문대학교·중소기업기술지원연구소 1998 선문공대 연구/기술 논문집 Vol.3 No.1

This study was performed to investigate the effect of Chungkuk Jang added-diets on reducing cadmium toxiclt in rats (Sprague-Dalvley, ♂, 125 58±4.04g) used as experimental groups. There are six experimental groups, a normal group(Tn), a cadmium treatment group(control group Tc), four cadmium and Chungkuk Jang (0.25%, 0 50%, 1 00%, and 1 50%; T_1 T_2, T_3, and T_4) treatment groups which received different dietary feeding for 8 weeks each The results are as follows. 1 The amount of food intake at Chungkuk Jang mixed group(T_1, -T_2) was 3 5% greater than at the Tc group For the group fed Chungkuk Jang the average of weight gain was 4.42g/day, which showed higher value(2.79%) than the Tc(4 30g/day) group. The food efficency rate of intake Chungkuk Jang group (5.02) was a little higher without significance than that of the Tn(4 91) and Tc(4 99) groups. 2. The amount of water intake was the highest in the Tn(32.44?/day) group and 30.14% greater than that of the Tc(21.66?/day) group. For the water intake (T_3) among Chungkuk Jang added-diet groups showed the highest value(22.78?/day) relatively Cadmium intake of each group was in the range of 1.94 to 2.27 ppm and the T_3 group showed the highest cadmium intake. For the growth rate the Tc group was 7.62% lower than Tn group but the Chungkuk jang fed group resulted in a reduced fashion-about 3% in the growth process against the Tn group 3 There was no significant weight gain or loss of the organ and bone of rats among the experimental groups but in the case of liver and kidney the T_3 (8.59%. 12 36%) was higher than the Tc group 4 Cadmium accumulation was high to low in order of liver > kidney > spleen > heart > lung > testicle > brain > femoral muscle > femur >(T_1, T_2, T_3, and T_4). tibia > blood. The 70% accumulation rate was showed in liver (33 2%), kidney (31.25) and spleen (6 1%). The contents of cadmium in tissue and body-hair in the Chungkuk Jang intake groups(T_1, T_2, T_3, and T_4) were lower than in the Tc group. The chungkuk Jang added-diet groups (T_3, and T_4) showed low levels of cadmium accumulation

나사형 임플란트 고정체의 길이, 직경, 플랫폼 형태에 따른 임플란트와 주위조직의 응력분포

강지은,정현주,양홍서 전남대학교 치의학연구소 2002 구강과학 Vol.14 No.1

Seven finite element models were constructed in mandible having single screw-type implant fixture connected to the second premolar-shaped superstructure, in order to evaluate how the length, diameter and platform shape of a screw-type fixture influence the stress in the supporting tissue around fixtures. The superstructure were made using UCLA abutment, and connected to the fixture with abutment screw. Each finite element model was varied in terms of length, diameter, and platform shape of the fixture according to the commercial fixture(3i Implant Innovations Inc, Palm Beach Gardens, FL33410, USA) while the superstructure and the mandible with a single fixture placed in it shared no difference in terms of appearance. In each model, 250N of vertical load was placed on the central pit of an occlusal plane and 250N of oblique load placed on the buccal cusp. The stress distribution in the supporting tissue and the other components was analysed using 2-dimensional Finite element analysis and the maximum stress in each reference area was compared. 1. Under lateral loading, the stress was larger in the larger in the abutment/fixture interface, and in the crestal bone, compared to the stress pattern under vertical loading. 2. The amount of stress at the superstructure was similar regardless of the length, diameter and platform shape of a fixture. 3. Around the longer fixture, the stress was decreased at the bone crest and subjacent cancellous bone and increased in the cancellous bone area apical to the fixture. 4. Around the wider fixture, the stress was decreased at the abutment/fixture interface, and the bone crest and increased in the cancellous bone area apical to the fixture. 5. Around the fixture having wider platform, less stress was resulted at the abutnent/fixture interface and the upper part of the cortical bone, compared to the fixture having standard platform. In short, the stress distribution of the supporting tissue was affected by length, diameter, and platform shape of a fixture, and the fixture which was larger in diameter and length could reduce the stress in the supporting tissues at the bone-fixture interface and bone crest area.

내러티브 중심 교과교육에 대한 교수, 교사, 학생의 인식 차이분석

주동범,강현석 이화여자대학교 교육과학연구소 2008 교육과학연구 Vol.39 No.2

Using a total of 702 people(71 professors, 299 teachers, and 332 students), the study was analyzing how do professor, teacher, and student perceive about narrative-centered subject education and the differences among groups in the perception. The main results are as follows. First, teacher group is positive about current subject education, but professor and student group are negative. Second, compared to teacher group, professor and student group are negative about current subject education and have more needs for change. And professors are positive about the applicability of narrative, but they are likely to have cautious stance about the composition and operation of curriculum. Professor and student group are more positive about specific application of narrative such as instructional syllabus, instructional materials, and the development of instructional material. Third, processor and student group are more positive than teacher group about the necessity of mutual complement of knowledge-based subject and narrative, and possibility of narrative will be selected as a new curriculum and the increment of its importance. However, teachers are more negative than students about narrative because teachers think narrative is highly possible to be limited to an instructional method simply. Discussions on main results and recommendations for further research were presented. 본 연구의 목적은 내러티브 중심 교과교육에 대해 관련 이해당사자라 할 수 있는 교수, 교사, 학생은 어떻게 인식하고 있으며 이러한 인식이 집단 간에 차이가 있는지를 실증적·경험적으로 분석하는 것이다. 내러티브 중심 교과교육에 대한 이론적 검토를 통해 제작된 질문지를 총 702명(교수 71명 , 교사 299명, 학생 332명)을 대상으로 실시하여 얻은 자료를 분석하여 나타난 주요 결과는 다음과 같다. 첫째, 현행 교과교육에 대해 교사집단은 다소 긍정적인 반면에 교수와 학생집단은 다소 부정적이다. 둘째, 교수와 학생집단이 교사집단에 비해 현행 교과교육에 대해 더 부정적이고 더 많은 변화 요구를 가지고 있다. 그리고 교수들은 내러티브 활용가능성에 대해 긍정적이나 내러티브 교육과정의 편성 및 운영에 대해서는 신중한 입장을 보이고 있다. 수업지도안, 수업 소재, 수업 자료 개발 등과 같은 구체적인 내러티브 활용에 대해 교수집단과 학생집단이 더 긍정적이다. 셋째, 교수집단이나 학생집단은 교사집단보다 주지교과와 내러티브의 상호 보완이 필요하다고 여기며, 내러티브가 새로운 교육과정으로 채택될 가능성과 그 중요성의 증가에 대해 더 긍정적이다. 반면에 교사들은 학생들에 비해 내러티브가 단지 수업 방식에 국한될 가능성이 높다고 보고 있어서 내러티브에 대해 다소 부정적이다. 주요 결과에 대한 논의 및 후속 연구를 위한 제언 등이 제시되었다.

전문가 시스템에서 지식의 그룹화와 추론 메타니즘

강현석,황용주,김용화 전북대학교 전자산업개발연구소 1990 전자산업연구 Vol.1 No.-

Most expert systems infer typically by using knowledges i.e.. rules and facts. If we grouped knowledges of the expert system effectively, it is very easy to maintain them. And we also can infer new knowledges from them efficiently because the inference is done only on a set of the finite grouped knowledges. In this paper, we propose a method in which some common attributed knowledges or some related knowledges are grouping efficiently. To show in we describe and algorithm which groups the rules of the expert system. and also we present a method which infers new knowledges by using the grouped knowledges.

災害 發生時 避難 危險度 算定 기준에 관한 硏究

姜良錫,金賢珠 弘益大學校 科學技術硏究所 1999 科學技術硏究論文集 Vol.10 No.1

Urban disasters such as earthquake or explosion cause fire and collapses, and the residents of the affected region happen to evacuate. The factors that influence the effectiveness of evacuation include the population as well as the street conditions and the surrounding physical environments of the region. While the size of the population, either residing or commuting, is basically determined by the region's land-uses, the street condition is dependent on its width, traffic volume, and the fixed or movable obstacles installed. The surrounding environments are a comprehensive consequence of the land-use planning and the general development patterns that dominate the uses, materials, structures, sizes, and densities of the buildings. Above three are in essence the primary factors that determine the effectiveness of evacuation in case of urban disasters. This study suggests the methods to evaluate the riskiness of evacuation in terms of these three factors. The riskiness thus measured could provide fundamental data to determine the priority of investments on urban facilities and to formulate the planning guidelines for rearrangement and maintenance of such facilities.

일개 대학병원에 내원한 원발성 폐암 환자의 인구학적 및 병리학적 특성

주혜원,강경필,김민근,박민석,임현민,이현경,이성순,이영민,김주인,염호기,최수전,이혁표 인제대학교 2006 仁濟醫學 Vol.27 No.-

Background : Recently, the lung cancer mortality rank first in Korea. The prognosis of lung cancer is not good enough with current treatments and multimodality treatments are required. So we are interested in the characteristics of lung cancer patients for better treatment. Methods : We searched lung cancer patients since 1994. Then we collected the data of primary lung cancer patients about the demographic features, histologic types and diagnotic methods. We divided the total period into 2 haves and specific analysis was tried. Results : 1) Total 850 patients were included. 633 (74.5%) were male and 217 (25.5%) were female. 2) The mean age was 65 ± 11 years old. and the peak age was 7th decades. 3) Squamous cell carcinoma(334/850, 39.3%) was slightly more prevalent than adenocarcinoma(302/850, 35.5%). Conclusion : From these results, we expected that older persons will be diagnosed to have lung cancer and adenocarcinoma will be more dominant histologic type with time.

지능장애를 동반한 근긴장성 이양증 환자에서 보인 앞쪽 측두엽 백질의 병변

강현구,정주리,이학승,장혁 圓光大學校 醫科學硏究所 2008 圓光醫科學 Vol.23 No.1

In myotonic dystrophy(MD), a characteristic myopathy is accompanied by abnormalities of other systems, including the brain. The pathogenesis of MD has not been clearly explained. Sometimes white matter lesion was noted on brain MRI, but its causative roles and association with intellectual impairment in MD was not clea yet. We report a case of myotonic dystrophy with intellectual impairment and temporal white matter lesions.

해운대 달맞이 언덕에 있어서 바다조망경관의 역사적 변천에 관한 연구

강영조,신수안,조미나,이현주,박은희 동아대학교 건설기술연구소 2000 硏究報告 Vol.24 No.1

The purpose of this study is to clarify the historic transition of the prospects on Haeundae dalmaji hill. Dalmaji hill is well known for a character of configuration on the ground with the scene of the sea. We will infer that how did it change the prospects of Dalmaji hill's sea through the analyzing of the preset situation and location of building on the hill. (1) We investigated the stories of the building, the history, the business condition. (2) We collect the twenty four view points which is able to have seascape on the hill, being easily approaching to the road, and condition of changing the building. (3) We clarified the transition of seascape prospect and considered the characteristics of the six types from which were divided the condition of seascape prospect.

급성 담낭염에 대한 내과적 치료의 역할

강성원,조한래,한설해,박현주,정인성,홍선미,김성걸,이헌영 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.2

In 58 patients who were admitted to department of internal medicine, ChungNam national university hospital from January 1989 to March, 1993. We evaluated for medical treatments and the following results were obtained. 1) The ratio of male and female was 1 : 1 and mean age of the patients was 57.4 years. 2) At arrival on hospital, the most common clinical symptom was pain in right upper quadrant and epigastrium(93.1%), the remainders were fever and chill(79.3%), nausea(51.7%) and vomiting(36.2 %) in order of frequency. 3) The most common physical findings was tenderness on the right upper quadrant and epaigastrium(98%), the remainders were jaundice(50%) and palpable gall bladder(13.8%) in order of freguency. 4) In laboratory examination, elevated levels of ESR(82.8%), leukocytosis(67.2%), elevated levels of AST(62.0%), ALT(50.0%), serum total bilirubin(51.7%) and alkaline phosphatase (43.1%) were noted. 5) The mean period of NPO was 3.9 days and the mean hospital period was 13.5 days. 6) The rates of combined complications in patients with acute cholecystitis were 17.2%; these are gall bladder empyema(5.2%), hydrops(5.2%), perforation(3.4%), sepsis(3.4%) and intestinal obstruction (1.7%). 7) In 96.6 percent of 58 cases, the symptoms of acute cholecystitis were improved by conservative management. 8) The mean follow-up period was 25.5 months and the recurrence rate was 10% during this period.

진행성 비소세포폐암의 이차항암화학요법으로서 Docetaxel 단독요법의 성적

강현모,이정은,장필순,이연선,권선중,안진영,정성수,김주옥,김선영 충남대학교 암연구소 2006 암연구소 업적집 Vol.5 No.-

Background : The survival benefit associated with first-line chemotherapy in lung cancer has led to the need for second -line chemotherapy, for which Docetaxel (Taxotere^(?)) has proven efficacy in both settings. This study evaluated the safety and efficacy of docetaxel in patients with non-small cell lung cancer who had failed first-line platinum-based chemotherapy. Methods : Thirty one patients with non-small-cell lung cancer, who had failed first line platinum-based chemotherapy, between March 1999 and August 2003, were enrolled in this study. Patients received intravenous docetaxel, either 75 mg/㎡ or 100 mg/㎡, with routine premedication every three weeks. Results : Fourteen patients (45.2%) had a partial response. The median survival and progression- free survival times were 12.5 months (95% CI 7.3-17.6) and 3.0 months (95% CI 1.6-4.5), respectively. This study showed 2 factors gave different survival benefits; the age (< 60 years: 20.1 months vs. > 60 years: 6.6 months, p=0.0105) and the histological type (adenocarcinoma: 25.6 months vs. others: 7.9 months, p=0.0055). The predominant toxicity was neutropenia, which occurred as WHO grade 3 or 4 in 38.7 % of patients. One treatment related death was also reported. Non-hematological toxicity was minor and easily controlled. There were no significant statistical differences in the survival benefit and toxicity between the two doses. Conclusion : Docetaxel, as second-line monotherapy, was well tolerated and effective in patients with non-small-cell lung cancer who failed first line platinum -based chemotherapy. (Tuberc Respir DiS 2005: 58: 465-472)