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정유진;손여림;황연숙 한양대학교 2009 韓國 生活 科學 硏究 Vol.29 No.1
The purpose of this study is to analyze, especially from a safety aspect, the interior characteristics of lobbies in the rehabilitation hospitals. Four rehabilitation hospitals in Gyunggi province were examined. The design features of lobbies were analyzed. The analyses were through on-the-spot surveys in the perspective of the safety features. The results of the study are as follows: The colors applied are relatively varied and in warmer tones but the finishing materials are relatively monotonous. Better finishing materials can give more intimate feelings to the users. Non-threshold entrances and slope ways are planned safely but lack in nonslip floor finish. The directional signs meet safety requirements in general but the visibility of sign needs to be improved.
전분의 첨가가 자몽 종자 추출물 DF-100의 항균 활성에 미치는 영향
이유진,김지훈,김영식,정영재,김경범,정종문 수원대학교 기능성생명소재연구소 2003 자연과학연구논문집 Vol.2 No.1
Recent testimonials report grapefruit seed extract DF-100 to be successful in combating a variety of common infectious agents. This study investigated DF-100 for antimicrobial activites at containing 3% corn starch, 3% wheat flour and 0.5~5% starch contents to determine if antimicrobial activity of DF-100 keeps almost constant or is sometimes decreased by the addition of various types of starch. In our study, grapefruit seed extract DF-100 was tested for antibacterial properties against 5 strains. Gram-negative and gram-positive isolates {Escherichia coli, Bacillus cereus, Staphylococcus aureus, Candida albians, and Yeast (be often contaminated strain in confectionery factory)} were introduced into various dilutions of DF-100 (0, 250, 500, 1,000, 2,000, 4,000, 8,000, 16,000 ppm) for determination of antimicrobial activity. The antibacterial effect of the DF-100 appears to suppress the. growth of the 5 strains used for experiment. However, antimicrobial activity of DF-100 was reduced 1/4 to 1/16 when added into foods (such as bread, noodle, and biscuits) containing corn starch, wheat flour, or potato starch. It was evident that the antimicrobial activity DF-100 was decreased by addition of starch.
천연식품 추출 혼합물인 디콜을 이용한 마우스와 랫드에서의 LDL-콜레스테롤, 중성지질 및 체중 감소효과
김지훈,김경범,이유진,정종문 수원대학교 기능성생명소재연구소 2004 자연과학연구논문집 Vol.3 No.1
This study was performed to investigate the effects of natural source extracts, Dechol. The effects of Dechol were investigated an the blood LDL-cholesterol, triglyceride, and body weights in the Sprague Dawley rats, transgenic mice (B6, 129-Ldlr^(tm1Her)), and ICH mice. Hyperlipidemia was induced in SD rats and ICR mice by feeding them with high-fat food. Transgenic mice were tested by feeding them with normal food. All animal experiments were divided into 2 groups. One group was treated in drinking 0.5% Dechol whereas the other group was fed with tap water. Dechol-treated SD rat group could be returned to normal blood LDL-cholesterol level almost in 9 days. ICR mice determination of LDL-cholesterol level showed that the difference after 4 weeks between two groups was 43 mg/dl. Transgenic mice indicated that the blood cholesterol concentration in the subject group was decreasing everyday whereas the one in the control group was increasing, resulting in the difference of 280 mg/dl between two groups just after 20 day-treatment. These results suggest that Dechol may be efficiently used for primary prevention of cardiovascular diseases.
요제프 호프만의 건축에서 나타나는 '비형상적' 장식의 시각적 효과와 그 의미에 관한 연구
이유진,정진국 대한건축학회 2001 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.21 No.1
After 1900, ornament in the architecture of Josef Hoffmann is appeared to form of contour line or geometrical pattern. But this ornament is 'non-figural' and different from the ornament of Vienna Art-Nouveau. The purpose of this study is to find the meaning of the 'non-figural' ornament that Hoffmann used in his architecture, through the visual effects of it. Hoffmann prescribes the wall as a distinctive unit by ornament. And the wall is seemed to be planar. This is related to visual environment that was newly appeared at that time. And this is a try to find new forms corresponding to his time.
한의학적 치료가 수술 권유받은 요추간판탈출증 환자의 임상 증상 및 삶의 질에 미치는 효과
이유진 ( Eu Gene Lee ),문수정 ( Soo Jung Moon ),고연석 ( Youn Seok Ko ),박태용 ( Tae Yong Park ),공재철 ( Jae Cheol Kong ),필감흔 ( Pi Chien Hsin ),송용선 ( Yung Sun Song ),이정한 ( Jeong Han Lee ) 한방재활의학과학회 2009 한방재활의학과학회지 Vol.19 No.4
Objectives: The purpose of this study was to report effectiveness of oriental medical treatments to symptoms and quality of life in the patients with herniated lumbar disc being suggested operation. Methods: Eighteen patients diagnosed with herniated lumbar disc by MRI in hospital were treated by oriental medical treatments. Symptoms of the patients were assessed by visual analogue scale(VAS) and SF-36. Results: After the treatments, the VAS of symptoms of herniated lumbar disc and the score of role-physical scale in SF-36 were improved but the other scores of scales were not significantly different. Conclusions: It could be suggested that oriental medical treatments were effective for the patients with herniated lumbar disc being suggested operation. Further study of the effect of oriental medical treatments on herniated lumbar disc is needed.
다발성 색전 폐렴을 동반한 Candida tropicalis 폐동맥 혈전증 1예
권유진 ( Eu Gene Kwon ),장현하 ( Hyun Ha Chang ),김신우 ( Shin Woo Kim ),김혜인 ( Hye In Kim ),긴효훈 ( Hyo Hoon Kim ),정주영 ( Ju Young Jeong ),정희연 ( Hee Yeon Jung ) 대한내과학회 2013 대한내과학회지 Vol.84 No.5
패혈성 폐 혈전색전증은 드문 질환으로 약물 중독자들에 흔하였으나 점차 감소하는 추세이며 중심 정맥 카테터의 사용, 인공 혈관 장치, 면역억제자와 관련성이 나타나고 있다. 저자들은 기저질환이 없는 건강한 젊은 환자에서 그라목손 음독으로 인하여 스테로이드와 cyclophosphamide 치료 후, 장기간 중심정맥 카테터를 통한 완전 정맥 영양을 시행하는 상태에서 발생한 진균혈증이 심내막염과 내안구염을 동반한 심한 다발성 색전 폐렴과 칸디다 폐동맥 혈전증을 유발하여 항진균제 치료 후 호전된 1예를 경험하여 문헌고찰과 함께 보고하는 바이다. Septic pulmonary thromboembolism resulting from fungal infection is rare. A 32-year-old woman with acute paraquat intoxication was treated with high-dose intravenous steroid and cyclophosphamide pulse therapy. She presented with a prolonged fever, dyspnea, and multiple pneumonic infiltrations. Central venous catheterization was necessary for total parenteral nutrition. The response to antibiotic therapy was disappointing and Candida tropicalis was cultured in the blood repeatedly. Vegetations were found in the superior vena cava on echocardiography and both pulmonary arteries had massive thromboembolism on computed tomography (CT). Intravenous amphotericin B and anticoagulation therapy showed improvement. When patients with central venous catheters and recurrent fungemia present with dyspnea and fever, septic pulmonary thromboembolism and other disseminated infections, such as infective endocarditis or endophthalmitis, should be kept in mind. (Korean J Med 2013; 84:759-763)
간기능 개선용 복합 식물 추출물(Hepa-1000)의 tert-butyl hydroperoxide(t-BHP)로 유도한 간세포 독성에 대한 보호 효과
이유진(Eu-Gene Lee),김경범(Kyung-Bum Kim),정종문(Jong-Moon Jeong) 한국식품영양과학회 2006 한국식품영양과학회지 Vol.35 No.9
본 연구에서는 간기능 개선제(Hepa-1000)의 t-BHP에 의해 유도된 산화적 스트레스에 대한 간세포 보호 효과를 확인하기 위해 인간 간암 세포주인 HepG2 세포를 이용한 세포실험으로 검증하였다. 간세포에 t-BHP로 유도되는 간세포의 산화적 손상에 대한 보호 효과를 측정한 결과, Hepa-1000을 처리시 대조군에 비해 유의적인 세포 생존율 증가치를 보이므로 간기능 개선제(Hepa-1000)가 t-BHP에 의한 간세포의 괴사에 대해 강한 보호 효과가 있음을 알 수 있었다. 또한 간기능 개선 효능을 확인하기 위해 세포 배양액 내의 GOT와 LDH의 활성도를 측정 시 t-BHP에 의해 간세포 손상이 확연하게 유발되었으며, 간기능 개선제(Hepa-1000)는 GOT와 LDH의 증가를 유의적으로 뚜렷하게 억제하였다. Hepa-1000의 t-BHP에 의해 유도된 산화적 스트레스에 대한 보호 효과를 세포막 손상 시 배양액 내의 세포 지질과산화 정도를 측정하는 MDA양을 측정하였을 때, Hepa-1000을 처리시 MDA의 양이 감소함을 관찰할 수 있었다. 이러한 결과들을 종합해 볼 때 간기능 개선제인 Hepa-1000은 간세포에서 t-BHP의 대사과정시 발생되는 free radical에 의한 세포내 지질과산화 현상을 방어하여, 세포막 손상 시 배양액으로 유출되는 GOT, LDH의 양을 감소시키므로 산화적 스트레스에 의한 간세포의 손상을 보호함으로써 인체에서 해독작용을 담당하는 조직인 간의 기능을 개선시키고 보호하는 효과를 나타내리라 사료된다. In the present study, the potential hepatoprotective effects of poly herbal formulation, Hepa-1000, against oxidative damages induced by t-BHP were evaluated in HepG2 cells in order to relate in vitro antioxidant activity with cytoprotective effects. The t-BHP induced considerable cell damage in HepG2 cells was shown by significant glutamic oxaloacetic transaminase (GOT) and lactate dehydrogenase (LDH) leakage, and increased lipid peroxidation. Hepa-1000-treated cells showed an increased resistance to oxidative challenge, as revealed by higher survival capacity than the one of control cells against t-BHP induced oxidative stress and hepatotoxicity. In addition, the Hepa-1000 had hepatoprotective effects lowering the activity of GOT and LDH, simultaneously. That is, it could inhibit the cell membrane damages resulting in the increased activities of GOT and LDH in the cell culture media. Furthermore, the Hepa-1000 could reduce t-BHP-enhanced lipid peroxidation, which was evaluated by measuring the production of malonedialdehyde. Based on the data described above, it could be suggested that the Hepa-1000 has significant hepatoprotective effects and plays a protective role against lipid peroxidation by free radicals.