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고객관계관리(CRM)에서 고객정보/고객지식 품질에 영향을 미치는 요인 : 서비스 산업을 중심으로 Focused on Service Industry
정현주,고준,김영걸 한국경영과학회 2002 經營 科學 Vol.19 No.2
It has been considered as a means for sustaining a competitive advantage for companies to build and maintain long-term relationships with customers. It is without any doubt that many companies have tried to initiate Customer Relationship Management (CRM). For the effective management of customer relationship, it is critical that they acquire, share and use customer information and knowledge. In this paper, we deduced 9 important factors affecting the quality of customer information and knowledge from the literature reviews on CRM, and developed the questionnaire to measure these factors. The factors are again categorized into organizational system, employees and IT. We analyzed data collected from 30 companies in service industries such as the finance, distribution and communication industries. The result of data analysis demonstrates that the employees' analytical skills and appraisal and reward systems are closely related to the quality of customer information, and analytical skills and IT support for communications with customers are associated with the quality of customer knowledge. Implications of findings and future research directions are discussed.
Jung Soo Kim,Yunjeong Kim,Song-Hee Han,Ji-Young Jeon,Minho Hwang,Yong-Jin Im,Jung Hyun Kim,Sun Young Lee,Soo-Wan Chae,Min-Gul Kim 고려인삼학회 2013 Journal of Ginseng Research Vol.37 No.1
A rapid, sensitive and selective analytical method was developed and validated for the determination of compound K, a major intestinal bacterial metabolite of ginsenosides in human plasma. Liquid-liquid extraction was used for sample preparation and analysis, followed by liquid chromatography tandem spectrometric analysis and an electrospray-ionization interface. Compound K was analyzed on a Phenomenex Luna C18 column (100×2.00 mm, 3 μm) with the mobile phase run isocratically with 10 mM ammonium acetate-methanol-acetonitrile (5:47.5:47.5, v/v/v) at a flow rate of 0.5 mL/min. The method was validated for accuracy (relative error <12.63%), precision (coefficient of variation <9.14%), linearity, and recovery. The assay was linear over the entire range of calibration standards i.e., a concentration range of 1 ng/mL to 1,000 ng/ mL (r² >0.9968). The recoveries of compound K after liquid-liquid extraction at 1, 2, 400, and 800 ng/mL were 106.00±0.08%, 103.50±0.19%, 111.45±5.21%, and 89.62±34.46% for intra-day and 85.40±0.08%, 94.50±0.09%, 112.50±5.21%, and 95.87±34.46% for inter-day, respectively. The lower limit of quantification of the analytical method of compound K was 1 ng/ mL in human plasma. The developed method was successfully applied to a pharmacokinetic study of compound K after oral administration in ten of healthy human subjects.
Young-Rye Kang,Hak-Yong Lee,Jung-Hoon Kim,Dea-In Moon,Min-Young Seo,Sang-Hoon Park,Kwang-Ho Choi,Chang-Ryong Kim,Sang-Hyun Kim,Ji-Hyun Oh,Seong-Wan Cho,Sun-Young Kim,Min-Gul Kim,Soo-Wan Chae,Okjin Kim 한국실험동물학회 2012 Laboratory Animal Research Vol.28 No.1
Yerba Mate, derived from the leaves of the tree, Ilex paraguariensis, is widely-used as a tea or as an ingredient in formulated foods. The aim of the present study was to evaluate the effects of Yerba Mate extract on weight loss, obesity-related biochemical parameters, and diabetes in high-fat diet-fed mice.To this end, by using in vivo animal models of dietary-induced obesity, we have made the interesting observations that Yerba Mate has the ability to decrease the differentiation of pre-adipocytes and to reduce the accumulation of lipids in adipocytes, both of which contribute to a lower growth rate of adipose tissue, lower body weight gain, and obesity. Our data from in vivo studies revealed that Yerba Mate treatment affects food intake, resulting in higher energy expenditure, likely as a result of higher basal metabolism in Yerba Mate-treated mice. Furthermore, in vivo effects of Yerba Mate on lipid metabolism included reductions in serum cholesterol, serum triglycerides, and glucose concentrations in mice that were fed a high fat diet. In conclusion, Yerba Mate can potentially be used to treat obesity and diabetes.
Jung Ah Min,Heon-Jeong Lee,이승환,Young-Min Park,Seung-Gul Kang,Young-Gyu Park,Jeong-Ho Chae 대한정신약물학회 2017 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.15 No.4
Objective: Recent studies have reported associations of retinoid-related orphan receptor alpha (RORA) gene single nucleotide polymorphisms (SNPs) with depression and anxiety disorders. Based on these, we attempt to test whether RORA polymorphism is associated with anxiety sensitivity (AS), the intermediate phenotype of depression and anxiety disorders. Considering gene-environment interactions and sex differences in AS, childhood maltreatment (CM) and sex were considered as confounders. Methods: Two-hundred and five healthy young Korean adults (female: 98, male: 107; age, 23.0±3.2 years) completed genotyping for the RORA SNP rs11071547, as well as measures for AS and CM. Generalized linear models were used to examine the main and interaction effects of RORA genotype, CM, and sex in determining AS. Results: The main effect of RORA polymorphisms was not found ( p =0.760) whereas the main effect of CM and interaction effects among sex, genotype, and maltreatment were significant on AS. In separate analyses by sex, the interaction effect between RORA genotype and maltreatment was significant only in males ( p <0.001). In females, the main effects of genotype and CM were significant (both were p <0.001), in which both a history of CM and C genotype tended to be associated with higher AS. Conclusion: The association between RORA polymorphism and AS might differ by sex. The interaction between RORA polymorphism and CM was significant only in males whereas RORA genotype and CM independently associated with AS in females. Further studies are encouraged to confirm the relationship between RORA polymorphism and AS.
Kim, Jung Soo,Kim, Yunjeong,Han, Song-Hee,Jeon, Ji-Young,Hwang, Minho,Im, Yong-Jin,Kim, Jung Hyun,Lee, Sun Young,Chae, Soo-Wan,Kim, Min-Gul The Korean Society of Ginseng 2013 Journal of Ginseng Research Vol.37 No.1
A rapid, sensitive and selective analytical method was developed and validated for the determination of compound K, a major intestinal bacterial metabolite of ginsenosides in human plasma. Liquid-liquid extraction was used for sample preparation and analysis, followed by liquid chromatography tandem spectrometric analysis and an electrospray-ionization interface. Compound K was analyzed on a Phenomenex Luna C18 column ($100{\times}2.00$ mm, 3 ${\mu}m$) with the mobile phase run isocratically with 10 mM ammonium acetate-methanol-acetonitrile (5:47.5:47.5, v/v/v) at a flow rate of 0.5 mL/min. The method was validated for accuracy (relative error <12.63%), precision (coefficient of variation <9.14%), linearity, and recovery. The assay was linear over the entire range of calibration standards i.e., a concentration range of 1 ng/mL to 1,000 ng/mL ($r^2$ >0.9968). The recoveries of compound K after liquid-liquid extraction at 1, 2, 400, and 800 ng/mL were $106.00{\pm}0.08%$, $103.50{\pm}0.19%$, $111.45{\pm}5.21%$, and $89.62{\pm}34.46%$ for intra-day and $85.40{\pm}0.08%$, $94.50{\pm}0.09%$, $112.50{\pm}5.21%$, and $95.87{\pm}34.46%$ for inter-day, respectively. The lower limit of quantification of the analytical method of compound K was 1 ng/mL in human plasma. The developed method was successfully applied to a pharmacokinetic study of compound K after oral administration in ten of healthy human subjects.
보문: 미립지공학·유동층·기후변화대응기술·연료전환기술 ; 벤치스케일(0.36 m × 22 m) 다단형 기포탑에서 다공판이 기포의 거동 및 기체 체류량에 미치는 영향
양정훈 ( Jung Hoon Yang ),허영걸 ( Young Gul Hur ),이호태 ( Ho Tae Lee ),양정일 ( Jung Ii Yang ),김학주 ( Hak Joo Kim ),천동현 ( Dong Hyun Chun ),박지찬 ( Ji Chan Park ),정헌 ( Heon Jung ) 한국화학공학회 2012 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.50 No.3
기포탑 반응기에서의 기체 체류량은 기포의 크기 분포 및 상승 속도와 밀접한 연관성을 갖는다. 따라서 많은 연구 자들에 의하여 기포탑 반응기 내에 기포의 크기를 제어하기 위한 연구들이 진행되어 왔다. 본 연구에서는 스파져 이외 의 영역에서도 기포의 거동을 제어하고 기체 체류량을 증진시키기 위하여 다단형 기포탑 반응기를 사용하였다. 특히, 3 종류의 서로 다른 크기의 반응기를 사용하여 다단 다공판이 기포의 유동 특성에 미치는 효과를 확인하였다. 나아가 개별 기포가 다공판을 통과하였을 때의 쪼개짐 빈도수 및 크기 분포 변화에 대하여 관찰함으로써 다공판의 영향에 대 한 이해를 넓혔다. 또한 다양한 다공판 배치 형태에 따른 유동 특성을 관찰함으로써 다단형 기포탑 반응기에서의 다공 판 설치에 대한 기준을 제시할 수 있었으며, 이를 바탕으로 높이 22 m, 직경 0.36 m의 벤치 스케일 다단형 기포탑 반 응기를 제작하여 그 성능을 확인하였다. The gas hold-up has a strong relationship with the size distribution and rising velocities of bubbles in a bubble column. Therefore, many previous researchers have studied on the hydrodynamics focusing on the bubble size variation in bubble column. In this study, the bubble behavior was influenced by partitioning porous plates installed at a certain height in a trayed bubble column. The gas hold-up was increased in non-sparging region (H/D > 5) as well as sparging region. We identified the effect of the partitioning porous plate using three trayed bubble columns with different reactor geometries. Furthermore, the bubble break-up frequency and size distribution were observed before and after individual bubbles penetrated through the plate. The arrangement of the plates was also investigated using a 0.15-m-in-diameter bubble column. Based on the result, we applied this design concept to a 0.36-m-in-diameter, 22 m tall trayed bubble column and identified the effect of the partitioning porous plate on the gas hold-up increase.
Gaba transporter <i>SLC6A11</i> gene polymorphism associated with tardive dyskinesia
Son, Woo-Young,Lee, Heon-Jeong,Yoon, Ho-Kyoung,Kang, Seung-Gul,Park, Young-Min,Yang, Hee Jung,Choi, Jung-Eun,An, Hyonggin,Seo, Han-Kyu,Kim, Leen Informa Healthcare 2014 Nordic journal of psychiatry Vol.68 No.2
<P>Background: Gamma-aminobutyric acid (GABA) insufficiency has been reported to be related to the tardive dyskinesia (TD) susceptibility. Inada et al. (Pharmacogenet Genomics 2008; 18: 317-23) identified eight genes belonging to GABA receptor signaling pathway that may be involved in TD susceptibility by genome-wide screening and they replicated associations in an independent sample for polymorphisms in SLC6A11 (GABA transporter 3), GABRG3 (c-3 subunit of GABA-A receptor) and GABRB2 (beta-2 subunit of GABA-A receptor). In this study, we tried to replicate their finding in a larger Korean sample and find if any of the genes was associated with the susceptibility to TD. Methods: We selected three polymorphisms in SLC6A11 (rs4684742), GABRG3 (rs2061051) and GABRB2 (rs918528) from the previous study. We carried out a case-control study (105 TD and 175 non-TD schizophrenic patients) to identify the association between the three candidate polymorphisms and susceptibility to TD and their epistatic interactions by using the multifactor dimensionality reduction (MDR) algorithm. Results: Among the three variants, SCL6A11 genotypes distribution showed a significant difference between the TD and non-TD patients (P = 0.049). However, GABRG3 and GABRB2 genotype distributions were not associated with TD (P = 0.268 and P = 0.976, respectively). Further, our analyses provided signifi cant evidence for gene-gene interactions (SCL6A11, GABRG 3 and GABRB2) in the development of TD. The odds ratio increased to 2.53 (CI = 1.515-4.217, P = 0.0003) when the genetic susceptibility to TD was analyzed with the three genes considered altogether through MDR approach. Conclusion: These results suggest that GABA receptor signaling pathway was associated with the increased susceptibility to TD in Korean schizophrenic patients.</P>