고도보정 공간내삽에 의한 전국의 1km²단위 기상실황 추정

윤진일,이동석,최재연,조성인,박은우,황헌 한국농업정보과학회 1999 농업정보과학 Vol.1 No.1

Conventional method of generating meteorological surfaces over geographic areas often neglects the elevation effect which is considered to be a single most important control over local climate. Deviation of the estimates may exrled practical limits at some areas with complex toprlgraphy. A digital map featuring coordinates and elevation data of 72 weather stations in Korea were joined with hourly weather(trmperature, relative humidity, precipitation and wind speed) observations at the stations by using a geographic information system software. An inverse distanre weighted interpolation was done on the point features to generate prim-itive meteorological and elevation surface grids consisting of 430×600 cells, respectively. Elevation difference at each cell between the United States Geological Survey's 1 km digital elevation model and this virtual ele-vation surface was calculated. Known relationships between meteorological elements and the elevation differ-ence were used to derive "correction grids" representing the potential effects of elevation difference at each grid cell. The correction grids were added or multiplied to the primitive meteorological surfaces to obtain ele-vation-corrected estimates for corresponding elements. This srheme was applied to hourly data of 27 March 1998 to generate the elevation-corrected mrteorological surfaces. Observed data of 350 automated weather sta-tions were used to partially validate the accuracy of the results. This simple scheme sHelved a feasibility of a near-real time generation of hourly meteorological surfaces for temperature and rainfall with an affordable error range.

身體 微細畸形 및 産科的 合倂症과 精神分裂症의 家族歷

홍경수,주연호,김용식,신철진,강웅구,이중서,정희연,주은정 大韓神經精神醫學會 1996 신경정신의학 Vol.35 No.4

저자들은 정신분열병의 일부에서는 태생기 동안 유전 외적인 환경적 요인이 크게 작용할 것이라는 가정 하에 형제 정신분열병 환자군(남 15. 여 7)과 산발성 정신분열병 환자군(남 16, 여 7) 및 정상 대조군(남 16, 여 7)을 대상으로 가족력에 따른 산과적 합병증과 신체 미세 기형을 비교하였다. 산과적 합병증은 Lewis 척도를 이용하여 연구 대상의 어머니와 면담하여 평가하였고 신체미세기형은 Waldrop 척도를 이용하여 측정하였다. 또한 산과적 합병증 및 신체 미세기형과 가족력에에 따라 발병 연령 등의 임상 양상들이 차이를 보이는지 비교함으로써 정신분열병을 좀 더 동질적인 아형으로 나눌 수 있는지를 검토하였다. 1) 형제 환자군, 산발성 환자군 및 정상 대조군의 세균에서 산과적 합병증의 개개의 항목 및 전체 점수의 유의한 차이는 없었다. 신체 미세기형의 경우 입의 미세기 형에서 유의한 차이가 있었으나 그 외에 각 부위별 점수 및 전체 점수에서는 세 군간에 유의한 차이가 없었다. 그러나 대부분의 신체 미세기형 세부 항목 및 전체점수에서 산발성 환자군이 형제 환자군에 비해 높은 신체 미세기형의 점수를 보이는 경향이 있었다. 2) 산과적 합병증의 전체 점수와 신체 미세기형의 전체 점수 사이에 상호 연관성을 찾아볼 수 없었다. 3) 발병연령·정신병리·약물에 대한 반응·병전 기능수준·지연성 운동장애 유무 등의 임상 양상들을 비교하였을때 산발성 환자군과 형제 환자군간에 유의한 차이가 없었다. 4) 산과적 합병증 및 신체 미세기형과 임상 양상들을 비교하였을 때, 형제 환자군에서 분만시간과 회복시 전반적 기능수준간에, 산발성 환자군에서 산과적 합병증의 전체 점수와 발병 연령간에 상관관계가 있었으나 전체적으로 일관된 결과가 도출되지는 못하였다. 위와 같은 결과를 종합하여 볼 때, 산과적 합병증이나 신체 미세기형이 정신분열병의 원인을 밝히는데 유익한 도구가 될 수는 있지만, 가족력 유무에 따라 정신분열병을 보다 동질적인 아형으로 구분하기 힘들다고 생각되었다. In order to test the hypothesis that familial schizophrenics have fewer chances of receiving organic insults during the fetal neural development than sporadic schizophrenics, the authors compared obstetric complications, minor physical anomalies, and other clinical features in sibling schizophrenics, sporadic schizophrenics and controls. Obstetric complications were evaluated by the scale of Lewis, and minor physical anomalies were measured by the Waldrop scale. Sporadic schizophrenics had a significantly higher Waldrop score for mouth than sibling schizophrenics. Although there was some tendency of higher total scores for minor physical anomalies in sporadic schizophrenics, there were no statistically significant differences in obstetric complications and the other minor physical anomalies among three groups. There was no significant correlation between obstetric complications and minor physical anomalies. The clinical features such as age of onset, psychopathology, response to drugs, premorbid functioning, and tardive dyskinesia were not significantly different between sibling and sporadic scizophrenics. In conclusion, while the obstetric complications and minor physical anomalies were suggested to be useful in the search for the cause of schizophrenia, it was difficult to categorize schizophrenics into more homogeneous groups according to family history of schizophrenia using the parameter of obstetric complications and/ or minor physical anomalies.

Brine Shrimp Bioassay를 이용한 해양생물의 세포독성검색

손병화,조용진,이대령,노연숙,이선미,최홍대 동의대학교 기초과학연구소 1994 基礎科學硏究論文集 Vol.4 No.1

As a part of chemical study on the bioactive metabolites from marine organisms, we have investigated cytotoxicity using brine shrimp bioassay for each solvent fractions of the marine algae(12 species), marine sponges(3 species), coelenterates(2 species), echinoderms(4 species), marine molluscs(17 species), and ascidians(2 species), respectively. As the results, chloroform extract of Stichopus japonicus (LC_50 : 274 ㎍/ml), ethyl acetate extract of Anthocidaris crassispina(LC_50 : 121 ㎍/ml), n-butanol extract of Undaria pinnatifida (LC_50 : 178 ㎍/ml), and water extract of Thais clavigera (LC_50 : 61 ㎍/ml), displayed the most significant cytotoxic activity against brine shrimp. Among the marine organisms tested, echinoderms and marine molluscs were thought to be the most active Phylums on screening of new bioactive compounds.

서울시내 고등학교 위탁급식의 급식비와 투자비의 실태 및 위탁업체의 기대수준 비교 분석

양일선,배환미,김현아,신서영,조미나,박수연,차진아,이보숙 한국식생활문화학회 2002 韓國食生活文化學會誌 Vol.17 No.5

The purposes of this study were to a) find out the operational characteristics of the contract-managed highschool foodservice in Seoul, b) investigate the expected level of meal-price and facilities investment cost perceived by contract-managed highschool foodservice managers c) compare the present level and expected level of meal-price and facilities investment cost. From October 12 to November 13 in 2001, the questionnaires were mailed to 249 high schools which was managed by contract foodservice company with respondent rate 40.2%. Data were analyzed using SPSS Win(10.0) for descriptive analysis and one group paired t-test. The results of this study were as follows ; 1. The student enrollment of highschools run by contract-managed foodservice was 1,243 with 72.6% participation rate of school lunch program. The average meal-price was 2,138 won. The average annual period of school foodservice operation was 156.78 days per year. The average contracting period was about 3 years. 2. The average cost concerned in the facilities investment amounts 169,578,180 won at the initial investment and 25,204,092 won at the repairs and maintenance cost in the course of operation. 3. The present level of meal-price and facilities investment cost were respectively 2,136won/meal and 171,157,336.72 won. And expected level.of meal-price and amount of facilities investment cost were 2,418.75 won and 121,353,215.19 won. Comparing the present level with expected level of the meal-price and facilities investment cost, expected level of meal-price was significantly higher than the present level of meal-price(p<.001) and expected level of facilities investment cost was significantly lower than present level of facilities investment cost(p<.001).

Genomic evidence of reactive oxygen species elevation in papillary thyroid carcinoma with Hashimoto thyroiditis

Yi, Jin Wook,Park, Ji Yeon,Sung, Ji-Youn,Kwak, Sang Hyuk,Yu, Jihan,Chang, Ji Hyun,Kim, Jo-Heon,Ha, Sang Yun,Paik, Eun Kyung,Lee, Woo Seung,Kim, Su-Jin,Lee, Kyu Eun,Kim, Ju Han Japan Endocrine Society 2015 Endocrine journal Vol.62 No.10

Vasomotor Symptoms: More Than Temporary Menopausal Symptoms

( Ki-jin Ryu ),( Hyuntae Park ),( Jin Seol Park ),( Yeon Woo Lee ),( Soo Young Kim ),( Hayun Kim ),( Youngmi Jeong ),( Yong Jin Kim ),( Kyong Wook Yi ),( Jung Ho Shin ),( Jun Young Hur ),( Tak Kim ) 대한폐경학회 2020 대한폐경학회지 Vol.26 No.3

Vasomotor symptoms (VMS), such as hot flashes and night sweating, are classic menopausal symptoms experienced by a majority of perimenopausal and postmenopausal women. VMS have received a great deal of attention due to their relationship with cardiometabolic risk. Further, accumulating evidence indicates that VMS are associated with an increased risk of several chronic diseases, including metabolic syndrome, type 2 diabetes mellitus, nonalcoholic fatty liver diseases, and osteoporosis in perimenopausal and postmenopausal women. These findings suggest VMS as biomarkers of impaired cardiometabolic conditions rather than just temporary symptoms in menopausal women, warranting further studies to confirm the casual relationship of VMS with these diseases and the exact underlying mechanism in this context.

산후조리원 내 신생아를 위한 원격 관리 시스템

정이진 ( Yi-jin Jung ),고지연 ( Ji-yeon Go ),위다연 ( Da-yeon Wi ),이혜빈 ( Hye-bin Lee ) 한국정보처리학회 2022 한국정보처리학회 학술대회논문집 Vol.29 No.2

본 연구는 산후조리원 내 신생아를 위한 원격 관리 시스템을 제안한다. 기존 시스템들은 공기질 문제만을 해결하거나, 모니터링 문제만을 해결하는 등 단순한 동작과 감시에 초점이 맞추어졌으나, 제안하는 시스템은 실내와 신생아 주변에 설치된 각각의 센서를 통하여 공기질을 포함한 실내 환경과 신생아를 모니터링하여 간호사와 산모가 쉽게 신생아의 건강을 웹과 앱으로 모니터링하고 원격으로 관리한다. 또한, OpenCV 라이브러리를 이용하여 신생아의 얼굴을 인식하고 표정별 이미지를 저장할 수 있도록 설계 및 구현하고 있다.

인쇄 방법을 이용한 인쇄 박막 트랜지스터 구현

노진수(Jin-Soo Noh),염동선(Dong-Sun Yeom),이민진(Min-Jin Yi),차화진(Hwa-Jin Cha),한주경(Ju-Kyung Han),정민훈(Min-Hun Jung),이광용(Kwang-Yong Lee),김다애(Da-Ae Kim),임소연(So-Yeon Lim),정경환(Kyung-Hwan Jung),강휘원(Hwi-Won Kang),조규진( 대한전자공학회 2010 대한전자공학회 학술대회 Vol.2010 No.6

Anticancer Activity of Peptide Fractions from Egg White Hydrolysate against Mouse Lymphoma Cells

Hye Jin Yi,Ji Yeon Kim,Kyoung Heon Kim,Hong Jin Lee,Hyong Joo Lee 한국식품과학회 2003 Food Science and Biotechnology Vol.12 No.3

Prenatally Diagnosed Uncommon Mosaic Autosomal Trisomy

Bom-Yi Lee,So-Yeon Park,Moon-Hee Lee,Jin-Woo Kim,Ju-Yeon Park,Eun-Young Choi,Yeon-Woo Lee,Ah-Rum Oh,Shin-Young Lee,Min-Hyung Kim,Hyun-Mee Ryu 대한의학유전학회 2009 대한의학유전학회지 Vol.6 No.1

Prenatal diagnosis of rare autosome mosaicism involvingchromosomes other than chromosome 13, 18, 21 or the sex chromosome is encountered prognostic dilemma during genetic counseling. We report four cases of level Ⅲ uncommon mosaicism of trisomy 5, 16 and 20,diagnosed prenatally. In case 1 with mosaic trisomy 20, there was a higher mosaic ratio of trisomy 20 in the repeat amniocentesis (62.1%) than in the first (36.6%) with normal fetal ultrasound finding except for a relatively small aorta on a 3-vessel view of the fetal heart. Case 2 showed a low rate of mosaic trisomy 20 (5.25%) in cultured amniocytes but normal karyotype in the repeat amniocentesis, who delivered a normal healthy baby. Case 3 showed a 13.6% of trisomy 16 mosaicism in the 30 cells of cultured amniocytes. Sixty cells from a fetal blood sample at termination showed non-mosaic 46,XX normal karyotype, while skin fibroblasts had 22.5% trisomy 16 in 40 metaphases. The autopsy showed ventricular septal defect (VSD). Case 4 with low grade mosaicism (10.5%) of trisomy 5 resulted in elective termination, though the ultrasoumd showed growsly normal fetus. Although level Ⅲ mosaicism is regarded as true mosaicism, it is difficult to predict the outcome of the fetus with rare mosaic autosome trisomy. Therefore mosaic autosome trisomy of fetus should be carefully interpreted with more various approaches including repeat sampling and targeted fetal ultrasound. 산전에서 성염색체와 13번, 18번, 21번 염색체를 제외한상 염색체의 모자이시즘은 발생빈도가 낮고 증례보고가 적어서 예후 예측이 어렵다. 저자들은 삼염색체성 5번, 16번, 20번의 산전진단 4례를 보고하고자 한다. 모자잌 삼염색체성 20번 2례 중 증례 1은 양수 염색체 검사에서 36.6%의 모자이시즘을 보였으나 재검한 양수 검사에서는 보다 높은 빈도 (62.1%)를 보였다. 증례 2에서는 양수 염색체 검사에서 모자이시즘 삼염색체성 20번이 5.25% 였으나, 재검 양수천자결과는 정상 핵형을 보였다. 증례 3은 30개의 양수세포에서 삼염색체성 16번의 모자이시즘이 13.6% 관찰되었다. 임신 종결 후, 총 60개의 태아 혈액 세포에서 모자이시즘 없는 정상 핵형이 관찰되었으나 태아의 피부 섬유아세포에서 얻은 40개의 중기상 세포에서는 22.5%의 삼염색체성 16번 모자이시즘을 보였다. 부검결과 심실중격결손(ventricular septal defect)이 관찰되었다. 증례 4는 76개의 중기상 세포에서 10.5%의 삼염색체성 5번 모자이시즘을 보였으나 태아의 초음파검사에서는 정상소견을 보였다. Level Ⅲ 모자이시즘은 진성 모자이시즘으로 간주되지만 발생빈도가 낮은 상염색체의 삼염색체성 모자이시즘은 태아의 예후를 예견하기 어려우므로 산전 진단시 여러 조직의 재검 및 태아 초음파 소견과 함께 다양한 임상적 접근 방법으로 그 해석에 신중을 기해야 할 것으로 사료된다.