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      • Fabrication of replica cliché with fine pattern using reverse offset printing process

        Shin, Yejin,Kim, Inyoung,Oh, Dongho,Lee, Taik-Min Elsevier 2018 THIN SOLID FILMS - Vol.647 No.-

        <P><B>Abstract</B></P> <P>Among the printing processes for printed electronic devices, the gravure offset and reverse offset methods have drawn attention for their fine pattern printing potential. These printing methods use a cliché, which has a decisive effect on the precision and quality of the final product. In this research, a precise cliché replica method is proposed. It consists of copper (Cu) sputtering, precise reverse offset printing with a 5-μm pattern width, nickel‑cobalt (Ni-Co) electroplating, rinsing, etching, and diamond-like carbon (DLC) coating. Cu is deposited on glass by sputtering to a thickness of 3μm. Ni-Co is electroplated to a thickness of 300nm only on the copper and not on the printed pattern. After removing the printed pattern during the rinsing process, Cu is etched through the revealed part resulting from the rinsing process. For the last step of the process, DLC coating is conducted to protect the surface. We finally compare the fabricated replica cliché with the original and print out precise patterns using the replica cliché.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The reverse offset printing method was adapted to replicate the fine pattern cliché. </LI> <LI> Silver nano ink pattern was dried but not sintered by controlling plasma treatment. </LI> <LI> The printed pattern with a line width of 4.8μm can be obtained using replica cliché. </LI> </UL> </P>

      • Comparison of organic and non-organic doenjang from physiochemical, antioxidant activities and sensorial perspectives

        Yejin Shin,Mina K. Kim 한국식품영양과학회 2021 한국식품영양과학회 학술대회발표집 Vol.2021 No.10

        The aim of this study was to compare organic and non-organic doenjang from physiochemical, antioxidant activities and sensorial perspectives. Two doenjang samples were included: Traditional doenjang made with non-GMO soybeans and organic doenjang using certified organic soybeans. Two samples were produced from same manufacturers at similar time frame. The physiochemical properties of doenjang were determined, and the antioxidant activity of doenjang was determined including total polyphenol, DPPH and ABTS. Descriptive sensory analysis using highly trained panel (n=6) was also conducted. There were no significant differences in pH, moisture content and °brix. Salinity, viscosity, and color between two samples. As for antioxidant activities, total polyphenol, DPPH, and ABTS values were higher in organic doenjang. Traditional doenjang showed sensory characteristics of fish sauce, chocolate, pear and organic doenjang showed pineapple, dried plum, and balsamic aromatics. This study suggests that the quality of doenjang that has undergone the same fermentation process may vary depending on the raw materials used.

      • SCOPUS
      • KCI등재

        Comparison of anti-influenza virus activity and pharmacokinetics of oseltamivir free base and oseltamivir phosphate

        Shin, Jin Soo,Ku, Keun Bon,Jang, Yejin,Yoon, Yi-Seul,Shin, Daeho,Kwon, Oh Seung,Go, Yun Young,Kim, Seong Soon,Bae, Myoung Ae,Kim, Meehyein MICROBIOLOGICAL SOCIETY OF KOREA 2017 JOURNAL OF MICROBIOLOGY -SEOUL- Vol. No.

        <P>Influenza viruses are major human respiratory pathogens that cause high morbidity and mortality worldwide. Currently, prophylactic vaccines and therapeutic antiviral agents are used to prevent and control influenza virus infection. Oseltamivir free base (OSV-FB), a modified generic antiviral drug of Tamiflu (oseltamivir phosphate, OSV-P), was launched in the Republic of Korea last year. Here, we examine the bioequivalence of these two compounds by assessing their antiviral efficacy in infected cells and in a mouse model. It was observed that both antivirals showed comparable efficacy against 11 different influenza A and B viruses in vitro. Moreover, in mice infected with influenza A virus (mouse-adapted A/Puerto Rico/8/34), they showed a dose-dependent therapeutic activity and alleviated infection-mediated reductions in body weight, leading to significantly better survival. There was histopathological disappearance of virus-induced inflammatory cell infiltration of the lung after oral treatment with either antiviral agent (at 10 mg/kg). Pharmacokinetic analysis also exhibited similar plasma concentrations of the active drug, oseltamivir carboxylate, metabolised from both OSV-B and OSV-P. This is the first report showing bioequivalence of OSV-FB to its phosphate salt form in the mouse system. The free base drug has some beneficial points including simple drug formulation process and reduced risk of undesirable cation-phosphate precipitation within solution. The long term stability of OSV-FB requires further monitoring when it is provided as a national stock in readiness for an influenza pandemic.</P>

      • SCISCIESCOPUS
      • KCI등재후보

        Trends of Artificial Intelligence Product Certification Programs

        Yejin SHIN,Joon Ho KWAK,KyoungWoo CHO,JaeYoung HWANG,Sung-Min WOO 한국인공지능학회 2023 인공지능연구 (KJAI) Vol.11 No.3

        With recent advancements in artificial intelligence (AI) technology, more products based on AI are being launched and used. However, using AI safely requires an awareness of the potential risks it can pose. These concerns must be evaluated by experts and users must be informed of the results. In response to this need, many countries have implemented certification programs for products based on AI. In this study, we analyze several trends and differences in AI product certification programs across several countries and emphasize the importance of such programs in ensuring the safety and trustworthiness of products that include AI. To this end, we examine four international AI product certification programs and suggest methods for improving and promoting these programs. The certification programs target AI products produced for specific purposes such as autonomous intelligence systems and facial recognition technology, or extend a conventional software quality certification based on the ISO/IEC 25000 standard. The results of our analysis show that companies aim to strategically differentiate their products in the market by ensuring the quality and trustworthiness of AI technologies. Additionally, we propose methods to improve and promote the certification programs based on the results. These findings provide new knowledge and insights that contribute to the development of AI-based product certification programs.

      • 하대정맥에 거치된 폐동맥 카테터 - 증례보고

        신예진(Yejin Shin),정기태(Ki Tae Jung) 조선대학교 의학연구원 2023 The Medical Journal of Chosun University Vol.48 No.2

        A 60-year-old male patient underwent liver transplantation surgery due to autoimmune cirrhosis and hepatocellular carcinoma. Placing a pulmonary arterial catheter (PAC) for hemodynamic monitoring was challenging despite using ultrasound and multiple adjustments. The PAC anomalously lodged in the inferior vena cava despite corrective attempts, influencing the surgical approach. To avoid possible complications, it was decided to remove the PAC. No subsequent complications related to PAC misplacement were observed, and the patient recovered post-surgery without incident. This case underscores the importance of following the precision in PAC insertion procedures, such as waveform analysis.

      • KCI등재

        블렌디드 러닝 탐구 실험 수업의 효과

        신예진(Shin, Yejin),우애자(Woo, Aeja) 한국열린교육학회 2011 열린교육연구 Vol.19 No.2

        본 연구의 목적은 블렌디드 러닝(Blended Learning) 탐구 실험 수업 방법을 개발하여 대학교「일반 화학 실험」수업에 한 학기 동안 적용한 후, 대학생들의 ‘과학 탐구 능력’, ‘학습 동기’, ‘과학 관련 태도’ 및 ‘수업 만족도’에 미치는 영향을 알아보는 것이다. 이를 위하여 실험 집단(N=20)에는 블렌디드 러닝 탐구 실험 수업을, 비교 집단(N=19)에는 전통적 실험 수업을 적용하였다. 블렌디드 러닝 탐구 실험 수업은 탐구 학습 모형을 바탕으로 ‘탐구 실험 문제의 도입’, ‘탐구 실험’, ‘보고서 작성 및 제출’의 3단계로 구성되며 온․오프라인 활동을 혼합하여 개발되었다. 블렌디드 러닝 탐구 실험 수업에 관한 본 연구의 결론은다음과 같다. 첫째, 면대면과 온라인상에서의 다양한 상호 작용과 교수자의 즉각적인 피드백이 학생들의‘과학 탐구 능력’과 그 하위 영역인 ‘기초 탐구 능력’, ‘통합 탐구 능력’을 통계적으로 유의미하게 향상시키는 것으로 나타났다. 둘째, ‘학습 동기’와 그 하위 영역인 ‘학습 신념의 통제’, ‘자기 효능감’이 통계적으로 유의미하게 높게 나타났다. 셋째, ‘과학 관련 태도’와 그 하위 영역인 ‘과학 탐구에 대한 태도’, ‘과학에 대한 취미적 관심’ 역시 통계적으로 유의미하게 높게 나타났다. 넷째, 실험 집단의 학생들에게 블렌디드 러닝 활동에 대한 ‘수업 만족도’ 설문을 실시한 결과, 동시적 웹 토론 학습이 유용하였고, 동료 학습자보다는 교수자의 즉각적인 피드백을 더 선호하고 있는 것으로 응답하였다. The purpose of this study is to examine the educational effects of a blended learning inquiry laboratory course when it is applied to a general chemistry laboratory course. Especially, the changes in 'inquiry ability', 'learning motivation', 'science related attitudes', and 'course satisfaction' of undergraduate students were examined. The blended learning inquiry laboratory course, based on inquiry learning, consisted of three stages: introduction to inquiry problems, inquiry experiments, and report writing and submission. Each stage was developed considering the online and offline activities. The experiment group (N=20) and the control group (N=19) carried out laboratory experiments separately, while having the same experiment topic for one semester. The result of this study is as follows. First, the blended learning inquiry laboratory course effectively improved 'inquiry ability' and its sub categories, such as basic process skills and integrated process skills, by providing various on/offline interaction and instant feedback to the students. Second, it is statistically effective on 'learning motivation' and its sub-categories, such as control of learning belief and self efficiency. Third, it is statistically effective on 'science related attitudes' and its sub categories, such as attitude toward science inquiry and interest in science. Fourth, when a course satisfaction survey was carried out, students responded that it was useful to participate in a synchronous web conference and they preferred web conferences with an instructor rather than with the students.

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