안면부 종창을 동반한 Henoch-Scho¨nlein 자반증 1례

이재휘,서무규,임문환,박성기,김태우,이창연 동국대학교 경주대학 1991 東國論集 Vol.10 No.-

We experienced a case of Henoch-Scho‥nlein purpura with are manifestation of facial swelling in a 7-year-old boy.

톨루엔을 포함한 유기용제의 직업적 폭로로 인한 신경내분비계 영향

이채언,이종태,정의화,손혜숙,문덕환,전진호,강정학,이창희,김휘동,김종한,정귀옥 大韓産業醫學會 1995 대한직업환경의학회지 Vol.7 No.2

Long term occupational exposure to solvent mixtures may cause adverse effects to the central nervous system with neurobehavioral symptoms. And some organic slovents have been suggested to cause impairment of tuberoinfundibular dopaminergic activity and neurochemical mechanisms controlling pituitary secretion. For the purpose of assessing neuroendocrine effects in occupational solvents exposure, hormonal study settings (shoes-manufacturing industry & fishing products industry) and compared with nonexposed controls(33 men, 85 women). Male workers exposed to solvent mixtures had significantly lower plasma level of follicle-stimulating hormone(FSH) than nonexposed male controls. While female workers exposed to solvent mixtures had significantly lower plasma levels of growth hormone(GH), and thyroid-stimulating hormone(TSH) than nonexposed female controls. The results of significant decrease in plasma concentrations of pituitary hormones(FSH, GH, and TSH) in workers exposed solvent mixtures indicate that occupational exposure to solvent mixtures may induce neuroendocrine effects through an effect on hypothalamic pituitary axis.

Preparation and quality characteristics of functional HALAL chicken thigh sausage containing tofu Residues (biji)

Tae-Hwi Moon,Sun-Goo Yim,Sun-Min Park,Ye-Lim You,Jung-Ah Han 한국식품영양과학회 2021 한국식품영양과학회 학술대회발표집 Vol.2021 No.10

As the Muslim population increases in Koea, there is an increasing demand for development the products that meet the needs of Muslim consumers, however, the relative studies or actual development is insufficient. In this study, sausages were prepared by acceptable materials to Muslim consumers - chicken thigh with different amount of tofu residues (biji) (0, 5, 10, 15, and 20%), and then the properties were compared. The pH of the sausage decreased as the amount of added biji increased. For color propertiesn, a* value decreased and b* value increased with the addition of biji. There was no significant difference in L* value, except for sample with biji 10%. As the addition of biji increased, hardness, springiness and chewiness increased, but cohesiveness and adhesiveness decreased. The biji powder improved the quality of sausage product in both sensory and functional properties, and the 10% addition (based on the weight of all of the materials) was chosen as the most acceptable.

Characteristics and storage stability of D-allulose solution

Tae-Hwi Moon,Jung-Ah Han 한국식품영양과학회 2022 한국식품영양과학회 학술대회발표집 Vol.2022 No.10

Characteritics of Green Kernal Black Bean with Different Roasting Conditions

Tae-Hwi Moon,Jin-Hee Chang,Jung-Ah Han 한국식품영양과학회 2021 한국식품영양과학회 학술대회발표집 Vol.2021 No.10

Diffierent roasting conditions were applied to green kernel black beans, and the properties were analyzed and compared. Green kernel black beans were roasted 110, 130, 150 and 170℃ for 10, 15 and 20 min, respectively, and raw beans were used as a control group. For color properties, L* value decreased as roasting temperature and time increased, whereas both a* and b* values increased. As roasting time and temperature increased, DPPH, ABTS radical scavenging effect, and total polyphenol content also increased. The antioxidant properties of roasted beans, except the sample roasted at 110℃, were significantly higher than those of raw beans. In particular, antioxidant properties were the highest in those roasted at 170℃ for 15 and 20 min. As roasting time and temperature of green kernel black beans increased, physiologically active substances increased, so roasting is thought to be necessary process for preparing functional beans, and the optimal condition was 170°C for 15 min, in this experiment.

볶은 서리태를 첨가한 영양 스콘의 개발 및 특성

문태휘(Tae-Hwi Moon),임수빈(Su-Bin Lim),한정아(Jung-Ah Han) 한국식품과학회 2022 한국식품과학회지 Vol.54 No.6

밀가루를 대체하여 볶은 서리태 분말을 첨가(0-50%)한 스콘을 제조하고 그 특성을 평가하였다. 반죽의 밀도는 서리태 분말 30%이상 첨가 시 증가하였으나 30-50% 첨가군간 유의적 차이는 없었다. 시료의 높이와 부피도 40% 이상 첨가 시 감소하였으나 40과 50% 첨가군간 유의적인 차이는 없었다. 굽기손실률은 서리태분말 20% 첨가군부터 감소하였으나 30-50% 첨가군 간 유의적 차이는 없었다. 수분함량은 대조군보다 서리태분말 10-40% 첨가군에서 유의적으로 증가하였으나 50% 첨가군에서는 대조군과 같은 수준을 보였고, pH는 서리태 분말 첨가량이 증가할수록 유의적으로 감소하였다. 색도는 껍질과 속질 모두 명도와 황색도는 유의적으로 감소하였고 적색도는 유의적으로 증가하였다. 스콘추출물의 DPPH 라디칼 소거능과 총 폴리페놀 함량은 서리태 분말 첨가량이 증가함에 따라 유의적으로 높아졌다. 제조한 스콘의 경도는 30% 대체군까지는 유의적 차이가 없다가 40% 첨가군부터 유의적으로 감소하였고 응집성은 서리태 분말 첨가량이 증가할수록 유의적으로 감소하였다. 탄력성 및 씹힘성은 첨가량에 따른 유의적인 차이를 보이지 않았다. 관능검사 결과 외관과 조직감은 20% 대체군이 가장 높게 평가되었으나 향, 맛 및 전반적인 기호도는 시료 별 유의적 차이를 보이지 않았다. 이상의 결과를 바탕으로 밀가루를 대체하여 볶은 서리태 분말을 함유한 스콘을 제조할 때, 30% 첨가수준까지는 제품의 부피나 조직감, 관능적 특성 등에 유의적 차이가 없으면서 항산화 활성이 크게 증가하는 것으로 나타나 서리태 분말 대체수준은 30%가 적합할 것으로 보이며 이 경우 단백질 강화효과(72.3% 증가)도 있는 것으로 나타났다. Scones were prepared using roasted seoritae powder (RS) as a substitute for wheat flour (from 0 to 50% RS content: RS 0, RS 10, RS 20, RS 30, RS 40, and RS 50). As the RS amount increased, the density of the dough and the protein content of the scone significantly increased, whereas the volume and baking loss decreased. The moisture content was also significantly decreased for RS 50. In terms of the antioxidant properties, both the free radical scavenging effect and total polyphenol content significantly increased, whereas the hardness and cohesiveness of the scones significantly decreased with an increase in the RS content. In the sensory test, RS 20 was the most preferred in terms of appearance and texture; however, there were no significant differences in the other properties among the samples. Based on the above results, the proper ratio of wheat flour replacement with RS was 30% for the scones; with this concentration, an increased antioxidant effect also can be obtained.

비지 분말 첨가 Halal 계육 소시지의 조직감 및 항산화특성

문태휘(Tae-Hwi Moon),박선민(Sun-Min Park),임선구(Sun-goo Yim),유예림(Ye-Lim You),한정아(Jung-Ah Han) 한국식품과학회 2022 한국식품과학회지 Vol.54 No.3

무슬림 소비자를 위한 육가공품 개발을 위해 할랄인증을 받은 계육에 비지 분말 첨가량을 0-50%까지 달리하여 소시지를 제조하고 그 특성을 비교 평가하였다. 비지 분말 첨가량이 증가할수록 소시지의 수분함량은 감소했으며, 식이섬유 함량은 증가하였다. 보수력은 비지분말 20% 첨가군까지는 증가하였으나 그 이상 첨가 시 감소하는 것으로 나타났다. 비지분말 첨가량이 증가할수록 시료의 pH는 감소하였고, 색도 특성에서 백색도는 감소, 황색도는 유의적으로 증가하였다. 소시지 추출물의 DPPH 라디칼 소거능은 비지 분말 첨가량이 증가함에 따라 유의적으로 높은 소거능을 보였고, ABTS 라디칼 소거능은 대조군보다 비지분말 첨가군이 유의적으로 높은 소거능을 보였으나, 비지 분말 첨가량에 따른 유의적인 변화는 없었다. 제조한 소시지와 시중에 판매되고 있는 Halal 인증 닭고기 소시지 제품의 경도를 측정하여 비교한 결과, 시제품의 경도는 266,678-896,654 N/m²의 범위였으며, 제조한 소시지의 경도는 409,840-769,210 N/m²의 범위로 비지 분말 첨가량이 많아질수록 유의적으로 증가하였다. 점착성은 20% 첨가군이 가장 높았고 40% 이상 첨가 시 유의적으로 감소하였으며, 응집성 및 탄력성은 첨가량에 따른 유의적인 차이는 없었다. 씹힘성은 50% 첨가군이 가장 높은 값을 보였으며 그 외 시료들은 유의적 차이가 없었다. 시제품 2개와 비지분말 1, 20, 30% 첨가군을 대상으로 기호도 검사를 실시한 결과 모든 시료가 외관에서는 유의적인 차이를 보이지 않았으며, 향은 대조군이 가장 높은 점수를 받았으나 그 외 시료 간에서 유의적 차이는 없었다. 맛은 대조군과 30% 첨가군이 가장 높았으며 상대적으로 시판 제품 2종은 낮게 평가되었고, 식감은 비지 분말을 첨가군이 시제품보다 높은 선호도를 보였으나 비지분말 첨가량에 따른 차이는 없었다. 전반적인 기호도에서는 대조군과 30% 첨가군이 가장 높게 평가되었다. 이상의 결과로 소시지 제조 시 비지분말을 첨가하는 경우 소시지의 보수력을 향상시키고 물성을 개선할 수 있으며, 식이섬유 함량과 항산화 활성을 높일 수 있는 것으로 나타났다. 무슬림 소비자 대상 관능검사 결과를 고려할 때 계육 소시지 개발 시 비지분말은 닭다리살 건조중량을 기준으로 30% 수준까지 첨가하는 것이 바람직할 것으로 보인다. To meet the needs of Muslim consumers, sausages were prepared using Halal-certified chicken thighs and different amounts of biji powder (0, 20, 30, 40, and 50%), and then the properties of the sausages were compared. As the biji powder levels increased, both the moisture content and the pH of the sausages significantly decreased, whereas their fiber content increased. As the biji powder levels increased, the free radical scavenging effect (DPPH, ABTS) and water holding capacity also increased, and the textural properties also improved. When Muslim consumers evaluated the sensory attributes of the sausages prepared in this experiment and those currently on the market, the ones prepared in this experiment were preferred over the market products. Based on the above results, chicken sausage for Muslim consumers could be successfully produced, and their overall quality and antioxidant effects could be improved by the addition of biji powder (up to 30%).

Dermoscopic findings of metastatic skin cancers: a single center experience

( Geun-hwi Park ),( Woo-il Kim ),( Min-young Yang ),( Won-ku Lee ),( Tae-wook Kim ),( Sung-min Park ),( Hyun-joo Lee ),( Gun-wook Kim ),( Hoon-soo Kim ),( Hyun-chang Ko ),( Byung-soo Kim ),( Moon-bum 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.2

Background: Though skin metastasis is rare, it can seriously affect the prognosis and management. The role of dermoscopy in primary skin cancers are established well, but its role in skin metastasis hasn’t been clear. Objectives: This study was performed to elucidate the dermoscopic patterns of metastatic skin cancers. Methods: We analyzed the dermoscopic patterns and clinical data of 46 patients with metastatic skin cancers at Pusan National University Hospitals (Busan and Yangsan) from 2005 to 2018. Results: Mean age and disease free interval were 62.0±14.2 years and 29.2±41.2 months, respectively. The most common primary origin of cancer was breast (11/46, 23.9%), followed by lung (8/46, 17.4%), and upper gastrointestinal tract (8/46, 17.4%). Any dermoscopic patterns was not found in 8 cases, who showed subcutaneous nodules without surface change. Most common dermoscopic pattern was vascular pattern (30/46, 65.2%), followed by homogenous structureless pattern (16/46, 34.8%). Most common vascular pattern was serpentine and arborizing vessel (23/46, 50%), followed by dotted vessel (7/46, 15.2%). There was no significant difference in dermoscopic vascular pattern among cancers, because the number of subjects was insufficient. Conclusion: Based on our study, when vascular patterns such as serpentine and arborizing vessel or dotted vessel are seen on dermoscopy within a nodule in a patient already diagnosed with cancer, metastatic skin cancer should be strongly considered.

Multiple eruptive dermatofibromas in a patient with myasthenia gravis treated by systemic corticosteroid

( Geun-hwi Park ),( Hyang-suk Ryu ),( Woo-il Kim ),( Min-young Yang ),( Won-ku Lee ),( Tae-wook Kim ),( Hyun-joo Lee ),( Gun-wook Kim ),( Hoon-soo Kim ),( Hyun-chang Ko ),( Byung-soo Kim ),( Moon-bum 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.1

Dermatofibroma is fibrohistiocytic tumor of the skin, commonly occurs as a solitary lesion on the lower extremities of young women. Multiple eruptive dermatofibromas (MEDFs), defined as presence of 5 to 8 dermatofibromas appearing within a period of 4 months, are rare and etiology of MEDFs is still unknown. However, they are frequently thought to be associated with altered immunity, such as autoimmune diseases and immunosuppression. It is unclear why MEDFs occur in association with these conditions, but this relationship may suggest that MEDFs are the result of an abortive immunoreactive process. We herein describe a middle-aged women who developed multiple dermatofibroma. She had myasthenia gravis for 8 years, and developed MEDFs after undergoing oral corticosteroid treatment (245 mg/wk) for 3 months. Therefore, our case could attribute to theory that using immunosuppressants works more dominant factor on occurrence of MEDFs than underlying immune disease.

Long second toe: its nail and skin changes

( Geun-hwi Park ),( Woo-il Kim ),( Min-young Yang ),( Won-ku Lee ),( Tae-wook Kim ),( Sung-min Park ),( Hyun-joo Lee ),( Gun-wook Kim ),( Hoon-soo Kim ),( Hyun-chang Ko ),( Byung-soo Kim ),( Moon-bum 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.2

Background: Nail can be affected by trauma, infection, and systematic disorders. In particular, the toe nails are exposed to the repeated and cumulative minor traumas, which usually result in thickened, splitted, and discolorated nails. Considering these, it can be inferred that the long second toe can be related to various nail and skin changes by repeated minor traumas such as friction in shoes, but the study or report on this topic hasn’t been done yet. Objectives: The purpose of this study was to introduce various nail and skin changes on long second toe. Methods: We analyzed the kinds of nail/skin changes of 50 patients with long second toe, enrolled at Pusan National University Hospitals (Busan and Yangsan) from 2013 to 2018. Results: There was no significant difference in the incidence of left and right toe and toenail, and 7 (14%) patients presented bilateral distribution. The most common nail change on long second toe was melanonychia (23, 46%), followed by subungual hematoma (15, 30%), onycholysis (2, 4%), subungual hyperkeratosis (2, 4%), onychomadesis (1, 2%), and retronychia (1, 2%). The most common skin change was corn (9, 18%), followed by paronychia (2, 4%). Twenty (20/50, 40%) patients also had other toe or toenail changes. Among them, the most common site was big toe/nail (13, 62%), and the most common change was subungual hematoma (8, 42%). Conclusion: Through this study, the dermatologists can recognize and diagnose the nail and skin changes of long second toe.