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유우개량을 위한 유단백질의 유전적 다형에 관한 연구 Ⅰ. αS1 - Casein 및 K - Casein 의 유전적 변이체
한상기(Sang K . Han),이기만(Khy M . Lee),정의용(Eui Y . Chung),장경진(Kyung J . Jang) 한국축산학회 1984 한국축산학회지 Vol.26 No.3
Genetic variants of αs₁-casein (αs₁-Cn) and K-casein (k-Cn) in milk proteins from 138 individual Holstein cattle in Korea were investigated by means of strach-gel-urea electrophoresis and the appearance of phenotypes, gene frequencies and genetic similarities were compared with those of foreign Holstein and of her breeds. The results are summarized as follows: 1. The milk proteins in cattle were controlled by codominant autosomal allelic genes of 9αs₁-Cn^A and αs₁-Cn^B(2 types), and K-Cn^A and K-Cn^B (2 types). 2. The distribution of phenotypes in each milk protein loci was αs₁-Cn BB 124, BC 14; K-Cn AA 76 Ab 49, BB 13. The number of phenotypes coxesponded closely to expectation of Hardy-Weinberg equilibrium (αs₁-Cn:0.7 $gt;P$gt;0.5, k-Cn;0.7$gt;P$gt;0.5). 3. Gene frequencies for genetic variants of the milk protein loci were analyzed. By the predominant allele in αs₁-Cn was αs₁-Cn B with a frequency of 0.949, whereas αs₁-CnC was in low gene frequency (0.051). Among the two alleles for K-Cn, K-Cn A gene showed to occur in high frequency (0.728). However, the Kin B was in low gene frequency (0.272).
Na 섭취제한,K 투여 및 이뇨 기간중 실혈성 Aldosterone 반응의 변동
고주환,유용운,이장규,성호경,박귀원 대한핵의학회 1977 핵의학 분자영상 Vol.11 No.1
고식염 섭취, Na 섭취제한, K 투여 및 이뇨기간중의 혈강 aldosterone 농도에 미치는 실혈의 영향을 정상 혈압을 유지하고 있는 청년 20명에서 관찰하여 아래와 같은 성적을 얻었다. 1) 실혈로 혈중 aldosterone 농도는 증가하였고 식염섭취제한이나 이뇨중의 실혈성 증가반응은 더욱 증대되었으나, K 투여로 aldosterone 농도가 이미 높은 개체에서는 증가반응을 가려낼 수 없었다. 2) 실혈시의 혈중 renin 활성도의 증가는 고식염식때 보다 Na 섭취제한이나 furosemide 이뇨시에 현저히 높았고 K 투여시의 실혈성 PRA 증가반응은 K를 별도로 투여치 않은 실험군과 별 변동이 없었다. 3) 실혈로 혈중 Na 농도에 큰 변동을 보이지 않았지만 모든 실험 조건하에서 감소경향은 나타내고 있었다. 4) 이상의 성적으로 보아 실혈에 의한 혈중 aldosterone 농도의 증가반응은 식염섭취제한이나 이뇨등의 부신 자극 요인이 있는 경우에 renin-aldosterone계의 활동 증가를 통한 aldosterone 분비의 가중현상을 보이나 K 섭취로 aldosterone 분비가 왕성한 기간중에는 실혈에 의한 renin 계의 aldosterone분비자극 첨가는 회의적이었다. Effect of sodium restriction with or without potassium supplement and furosemide diuresis on plasma aldosterone response to mild hemorrhage wese studied in normotensive young volunteers. After an overnight fast, blood were drawn just before and 10, 20, 30, 50, 70, 90, and 120 minutes after the 3H-aldosterone injection. The sum of blood delivered reached over 100ml (during two hours). Plasma aldosterone and renin were measured by means ot radioimmunoassay. The results were as followed; 1) Hemorrhage resulted in a moderate increase in plasma aldosterone level of volunteers with normal diet. 2) The mean figures of plasma aldosterone in subjects with sodium restriction and diuresis were likewise significantly increased by hemorrhage, however, the figure of the subjects with potassium supplement who already shown higher plasma level was without effect on hemorrhage. 3) Hemorrhage produced slight decrease in serum sodium concentration in every experimental conditions, although the changes were not significant. 4) Plasma renin activities after the hemorrhage followed a similar pattern with that of aldos terone, increased during sodium restriction cr diuresis and unaffected during potassium supplement. $quot;
성정호,성규보,이승로,함창곡 한양대학교 의과대학 1984 한양의대 학술지 Vol.4 No.1
Tuberous Sclerosis is a rare congenital disease of neuroectodermal origin, inherited as AD, and known as Bourneville's disease or Epiloia. This lesion has clinical triad of mental retardation, seizure and adenoma sebacevm, and associated hamartoma or cyst is found at any organ, especially at brain, skin and kidney. In brain, hamartomas are found largely at cerebrum and more specifically at subependymal layer of ventricle, especially near the foramen of Monro. Authors experienced 2 cases of Tuberous Sclerosis, who have typical clinical symptomes and Computed Tomographic findings of brain and kidney, and reported with a brief review of the literatures.
이면우,유한정,김상두,오세관 한국경영과학회 1989 한국경영과학회 학술대회논문집 Vol.- No.1
The purpose of this study was to demonstrate and to validate feasibility of the earlier proposal on ergonomic approach for High-Touch product development, which was published in IE Interface (April, 1988). Based on the proposed methods, six new High Touch products were developed. Expert opinions and consumer monitoring results, which was carried out in the United States, showed that these High Touch products would be highly regarded in the world market. It is recommended that the proposed efforts could provide a prosperous niche market for Korean industry in the High Tech-High Touch Era.
Sung G.Y.,Choi, C.H.,Suh J.D.,Han, S. K.,Kang, K.Y.,Hwang, J.S.,Yoon, S.G.,Jung, K.R.,Lee, Y.H.,Kang, J.H.,Kim, Y.H.,Hahn, T.S. The Korean Superconductivity Society 1999 Progress in superconductivity Vol.1 No.1
We have fabricated and tested a simple circuit of the rapid single-flux-quantum(RSFQ) four-stage shift register using a single layer high-$T_c$ superconducting (HTS) $YBa_2Cu_3O_{7-x}$ (YBCO) thin film structure with 9 step-edge Josephson junctions. The circuit includes two read superconducting quantum interference devices(SQUID) and four stages. To establish a robust HTS RSFQ device fabrication process, we have focussed on the reproducible process of sharp and straight step-edge formation as well as the ratio of film thickness to step height, t/h. The spread of step-edge junction parameters was measured from each 13 junctions with t/h=1/3, 1/2, and 2/3 at various temperatures. We have demonstrated the simplified operation of the shift register at 65 K.