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      • 대동맥 이첨판과 승모판 이탈증을 동반한 대동맥 판하부 협착 1예

        김용화,장경식,양태영,임영국,안기완,홍순표 朝鮮大學校 附設 醫學硏究所 1993 The Medical Journal of Chosun University Vol.18 No.1

        Discrete subaortic stenosis is a rare cardiac disorder especially in Orientals which occupies eight to ten percent of aortic stenosis, It occurs mainly before age of eighteen and accompanies with aortic valve abnormalities such as aortic stenosis, supravalvrlar stenosis, bicuspid valve and muscular hypertrophic subaortic stenosis, and other cardiac abnormalities such as ventricular septal defect, pulmonary stenosis and coarctation of aorta. There is no report of discrete subaortic stenosis accompanied with mitral valve prolapse. The major complications of discrete subaortic stenosis are aortic insufficiency, and subacute bacterial endocarditis. We report a case of asymptomatic nineteen-year-old male of discrete subaotic stenosis with bicuspid aortic valve and mitral valve prolapse, which is comfirmed by two-dimensional and Doppler echocardiography including transesophaigeal echocardiography.

      • 보행시 하지체질의 내적일 분석

        홍성표,이순호,김희수 忠南大學校體育科學硏究所 1995 體育科學硏究誌 Vol.13 No.1

        This study is to represent basic data of biomechanical work of human body which has been data measured precisely and is to see on pathology and abnormal gaits patterns. And 5, 6th grade boys in Taejon city were attended in this experiment. Each student wore 8 landmarks on their lower leg joints and walked for 4 Km/h, 5 Km/h, and 6 Km/h on the treadmill Mechanical energy of lower extremity segment by lower joint (thigh and shank) movement were measured in stance phase and swing phase which were assessed internal work and energy of segment The conclusions were as following; 1. Increasing gait velocity cause toe off in early stage and swing of lower extremity happen early and quickly with angle of shank increasing in swing phase. 2. Children gait velocity grow rapidly above 5km/h, internal work of thigh mechanical energy showed value of work clearly and large. and internal work change represent greater in shank than in thigh 3. The stance period of gait is the period off set by two operated cocontracting muscles, and the later the speed of gait is, the lower the effect of the net torque.

      • 高溫菌이 分泌하는 蛋白質分解酵素에 關하여

        洪淳德,金鍾國 慶北大學校 1982 論文集 Vol.33 No.-

        A Thermophilic bacterium which produced proteolytic enzyme potently was isolated through the nightsoil composting process. Culture conditions for protease production, purification of protease and some properties of purified enzyme were investigated. Results are as follows. Optimal temperature and moisture content for production of protease by this strain was 50℃, 60%, respectively. The quantity of enzyme produced by this strain was maximized in 24 hours culture. When cultural fluid was spurified by ammonium sulfate precipitation, dialysis. DEAE-cellulose and CM-cellulose, purification resulted in 218.2 fold increase in the specific activity with a recovery of 10.32% of original activity. The Km value for this enzyme was 12.2mg/ml. Optimal pH and temperature for enzyme activity were 9.0, 60℃, respectively, and the enzyme was most stable at pH 8. Of various metal salts, CuCl_2 promoted the enzyme activity to 21.6%, whereas HgCl_2 inhibited it to 86%. Theatment of EDTA showed no effect on enzyme activity, and this strain was similar to Bacillus licheniformis.

      • KCI등재
      • Mossbauer 분광법을 이용한 제주 화산암의 미시적 연구와 그 응용

        홍성락,고정대,김순희 濟州大學校 基礎科學硏究所 1994 基礎科學硏究 Vol.7 No.1

        제주도 전 지역의 특정위치를 선정하여 그 위치에 따라 지하 60m, 61m, 87m, 99.5m, 220m까지 깊이별로 화산암 시료를 채취하여, 이 시료에 대한 SIMS, XPS와 Mossbauer spectroscopy의 실험결과를 보고한다. UHV chamber에서 분리 이온화에 의해 생겨 난 parent 이온들로부터 cracking pattern들에 대해 연구하였고, 그 parent 이온들은 Si??, Al??, Ca??, Mg??, Fe??, Fe??, Na?, k?등으로 나타났다. 이 시료들에 대한 XPS 실험에서 wide scan analysis를 통하여 시료 표면에서 Al, Si, Ca, O, Fe, Na 등의 원소가 존재하고 있음을 알 수 있었으며, narrow scan analysis를 통하여 이들 대부분이 single compound state를 나타내고 있음을 발견할 수 있었다. 화산암에 대한 Mossbauer spectrum으로부터 olivine, pyroxene, ilmenite에 의한 세쌍의 quadrupole splitting을 얻었으며, 각 광물에 함유된 Fe는 약간의 Fe??를 제외하고는 거의 모두 Fe??상태임을 확인하였다. We are reporting the results of measurements of the SIMS, XPS, and ??Fe Mossbauer spectrum for powder samples of volcanic rock which has been distributed throughout different areas on Cheju island, each in different depth beginning at 60m then 61m than 61m, 87m, 99.5m, and 220m. We have studied the cracking patterns from parent ions which are created by dissociative ionization in the UHV chamber. The parent ions were Si??, Al??, Ca??, Mg??, Fe??, Fe??, Na??, and k??. In the XPS results for these samples, we find the existence of elements Al, Si, Ca, O, Fe, Na on their surfaces through the wide scan analysis. Also, the single compound state has appeared in a greater percentage of the them through the narrow scan analysis. The Mossbauer spectrum consists of well defined quadrupole doublets having a dominant 2+ charge state with a small percent having a 3+ charge state. These indicate the presense of olivine, pyroxene, and ilmenite.

      • SCIESCOPUSKCI등재
      • 식도암의 임상적 고찰

        김만중,김만우,채종구,정춘해,홍순표,조건국 朝鮮大學校 附設 醫學硏究所 1987 The Medical Journal of Chosun University Vol.12 No.1

        A Clinical observation was made in 52 cases of patients with esophageal cancer at Chosun University Hospital during about 5years from january 1981 until may 1986. The following results were obtained: 1. The peak age of patients was fifth decade. The average age of patients is 55.7 years old. The sex ratio is 7.6 : 1 with a greater prevalence male. 2. Duration of the disease before admission was relatively long, about 4~6 months is 48% of all case. 3. The most common initial symptoms were swallowing difficulty, weight loss, substernal pain. 4. On the majority of patients, Heavy s.noking was manifested. 5. In blood type, A type was predominent. 6. In location of tumor, 69.2% of total cases were located in mid esophagus. 7. In histopathologic finding, 73% of total cases was squamous cell ca.

      • SCIESCOPUSKCI등재
      • KCI등재후보

        Lidocaine, Thrombin, Epinephrine 의 항균효과

        김진우,이동건,전혜선,김승준,김석찬,안중현,김치홍,권순석,김영균,김관형,문화식,신완식,송정섭,박성학 대한감염학회 2005 감염과 화학요법 Vol.37 No.6

        목적 : 기관지내시경 검사에서 흔히 사용되는 국소마취제인 lidocaine과 내시경시 지혈목적으로 사용되는 thrombin과 epinephrine이 각종 균주에 미치는 항균효과에 대해 알아보고자 하였다. 재료 및 방법 : 균주는 가톨릭대학교 성모병원에서 2004년 3월부터 2004년 9월까지 임상검체 에서 동정된 S. aureus, S. pneumoniae, K. pneumoniae, P. aeruginosa 각각 42, 42, 42, 43주를 대상으로 하였다. Lidocaine, thrombin, epinephrine 감수성 검사는 National Committee for Clinical Laboratory Standards (NCCLS, 2002)의 기준에 따랐다. 결과 : Lidocaine은 S. aureus, S. pneumoniae, P. aeruginosa에서 MIC_(50), MIC_(90) 모두 20,000 ㎍/mL 이었다. K. pneumoniae는 각각 10,000 ㎍/mL이었다. Thrombin은 S. aureus와 P. aeruginosa에서 MIC50 500 lU/mL 과 MIC_(90) 500 IU/mL 이상이었고, K. pneumoniae에서는 MIC_(50)과 MIC_(90)이 모두 500 lU/mL이상이었으나 S. pneumoniae에서는 MIC_(50)과 MIC_(90)은 125 IU/mL이었다. Epinephrine은 K. pneumoniae, S. pneumoniae에 대한 MIC_(50), MIC_(90)가 모두 >500 ㎍/mL이었고, S. aureus와 P. aeruginosa에 대한 MIC_(50), MIC_(90)가 모두 500 ㎍/mL이었다. 결론 : 기관지 내시경 검사에서 흔히 쓰이는 lidocaine, thrombin, epinephrine 등의 약제들이 호흡기 질환의 흔한 병원균인 S. aureus, S. pneumoniae, K. pneumoniae, P. aeruginosa 균주들에 대해 항균 효과가 있을 수 있어 세균배양검사에 영향을 미칠 수 있겠다. Background : We performed this stody to find out about antimicrobial effect of lidocaine which is commonly used local anesthetic, and thrombin and epinephrine used for hemostasis during bronchoscopic procedures. Materials and Methods : The microorganisms that were cultured from specimens obtained during bronchoscopy were Staphylococcus aureus (n=42), Streptococcus pneumoniae (n=42), Klebsiella pneumoniae (n=42), and Pseudomonas aeruginosa (n=43) collected from St. Mary's Hospital, from March to Sep 2004 were used for susceptibity testing. Susceptibility to lidocaine, thrombin, and epinephrine were tested according to the National Committee for Clinical Laboratory Standards. Result : MIC_(50) and MIC_(90) of lidocaine for S. aureus, S. pneumoniae, P. aeruginosa were all 20,000 ㎍/mL and that for K. pneumoniae were 10,000 ㎍/mL. MIC_(50) and MIC_(90) of thrombin for both S. aureus and P. aeruginosa was 500 IU/mL and above 500 IU/mL, respectively; that for K. pneumoniae were all above 500 IU/mL and for S. pneumoniae they were 125 IU/mL, MIC_(50) and MIC_(90) of epinephrine for K. pneumoniae and S. pneumoniae were above 500 ㎍/mL; that for S. aureus and P. aeruginosa were 500 ㎍/mL. Conclusion : We observed possible antimicrobial effect of lidocaine, thrombin, and epinephrine in vitro against pathogens such as S. aureus, S. pneumoniae, K. pneumoniae, P. aeruginosa, which are common respiratory microorganisms. The use of these agants could affect the result of bacterial culture.

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