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      • 건강검진자를 대상으로한 갑상선질환의 유병률 조사

        석성자 ( Seong Ja Seok ),신두만 ( Du Man Shin ) 대한임상검사과학회 2007 대한임상검사과학회지(KJCLS) Vol.39 No.2

        This study was carried out on 14,443 subjects (8,706 men, 5,737 women ; between 20-80 years of age, mean age 41.8 ± 9.16) who visited the health promotion center of one university hospital. Serum T3, T4 and TSH concentrations were measured with CIA using commercial kits on ADVIA Centaur Assay. The prevalence of thyroid disfunction was high in elderly people and women like in western countries. The results were as follows; 1. The prevalence of overt hyperthyroidism was 4.8/1,000 population (men 4.1/1,000, women 5.9/1,000) and was higher in women than in men. 2. The prevalence of subclinical hyperthyroidism was 10.7/1,000 population (men 9.0/1,000, women 13.2/1,000) with peak prevalence at the age group 50, 60 and was higher in women than in men. 3. The prevalence of overt hypothyroidism was 0.5/1,000 population (men 0.5/1,000, women 0.5/1,000). The prevalence increased with age and was significantly higher in women in the age group over 60 years. 4. The prevalence of subclinical hypothyroidism was 12.6/1,000 population (men 6.0/1,000, women 22.7/1,000) and was as high as about 4 times in women than in men. 5. The prevalence of thyroid dysfunction was higher in women than in men in all the age groups, and was higher in the age group 50, 60 years than in any other age group.

      • Urapidil, Labetalol의 투여가 기관내 삽관시 심혈관계에 미치는 영향

        신용섭,윤석화,손수창,이원형,이정은,황원재,김만수,김영주,김혜자,최세진 충남대학교 의과대학 지역사회의학연구소 1994 충남의대잡지 Vol.21 No.2

        We have examined the comparative efficacy of small doses of intravenous urapidil and labetalol in blunting hemodynamic response to endotracheal intubation and surgical incision in 30 patients without cardiovascular diseases. After intravenous urapidil 0.2 mg/kg or labetalol 0.2 mg/kg anesthesia was induced with thiopental 5mg/kg. Endotracheal intubation was facilitated by vecuronium 0.15 mg/kg with priming principle and anesthesia was maintained with enflurane and nitrous oxide in oxygen. Systolic, diastolic and mean arterial pressure and heart rate were measured before administration of the drugs, 5 minute after administration, just prior to endotracheal intubation and 1, 3, 5, 10 minute after intubatin. Also the peak blood pressures and heart rate within 10 minutes after surgical incision were measured. Endotracheal intubation and surgical stimulation were associated with significant increases in blood pressures and heart rate in both urapidil and labetalol group. Comparison of the changes in systolic, diastolic, and mean artrial pressures and heart rate between urapidil and labetalol group showed no significant difference except peak systolic pressure after surgical incision. It is concluded that the pressor response to endotracheal intubation and surgical stimulation are not influenced significantly by urapidil 0.2 mg/kg or labetalol 0.2 mg/kg. However, urapidil and labetalol preloading may be similarly effective in the blunting of the increases in blood pressures with larger doses of the durgs during anesthetic induction.

      • 전류형 능동필터를 위한 전압제어형 델타변조방식의 해석

        신우석,최규하,정만규 건국대학교 산업기술연구원 1994 건국기술연구논문지 Vol.19 No.-

        This paper describes voltage-controlled delta-modulation scheme for active power filters, which is to control the harmonic-compensating current indirectly by adjusting the capacitor voltage to be sinusoidal. The overall control system has two feedback loops : one is the outer proportional feedback for loop regulating the de current of the active filter and the other is the inner feedback loop for maintaining the ac current waveform to be sinusoidal, and to have zero power factor angle(i. e. unity power factor). The characteristics of the proposed scheme are investigated by digital simulation using ACSL.

      • SCOPUSSCIEKCI등재
      • 光州·全南地域의 流通産業 硏究 : 農·水産物을 中心으로 Laying Emphasis on Agricultural and Marine Goods

        崔錫信,朴萬石,朴炯昊 全南大學校企業經營硏究所 1991 産業經濟硏究 Vol.14 No.1

        The purpose of this study is twofold. The first is to propose some remedies for the basic problems which might be induced from the present states of marketing of agricultural and marine products in Kwangju/Chonnam area. The second purpose is to justify the vitalization of conventional market system by comparing the domestic or intermediate-technology approach to the improvement of food marketing in this country with the high-technology approach originating in industrial nations. To pursue this purpose, the literary research on the above two approaches to the improvement or modernization in agricultural and marine goods marketing was followed by the empirical research on the attitude of consumer group as well as seller group about conventional markets in comparison with other markets. It leaves no room for doubt that the degree of consumer satisfaction should be included into the evaluation of marketing performance. And, consumers in sample generally perceive that they prefer conventional markets to the other types of market especially in such respects of spatial convenience, price, product quality, product variety or assortment breadth, and the ease of one stop shopping. But this is not to say that modern types of marketing institution such as supermarket can make no contribution, for this is not the case. As the result of the present study, it is suggested that high efficiency in agricultural and marine products marketing can be achieved through adopting the domestic intermediate-technology and improving the operations and business skills of conventional markets. It should be noted that since the high technology solution of the vertically integrated chain stores is one of dubious value for the problems that are latent in food marketing, alternative procedures must be sought.

      • 불안장애환자가 나타내는 사고내용의 특성

        원호택,신현균,박현순,권석만 서울大學校 社會科學大學 心理科學硏究所 1996 心理科學 Vol.5 No.1

        본 연구는 인지내용이 정서장애에 영향을 미친다는 인지적 내용-특수성 가설에 근거하여 불안장애환자의 사고내용을 조사하고자 했다. 사고내용에 있어서, 불안장애 환자들이 정상인 또는 비불안 정신장애환자와 어떤 차이점이 있는지를 조사했으며 나아가서 불안장애의 하위유형인 공황장애환자와 비공황 불안장애환자간에 어떤 차이점이 있는지를 탐색하고자 했다.이를 위해서 공황장애환자 34명, 비공황 불안장애환자 24명, 비불안 정신장애환자 34명을 포함한 92명의 정신장애 환자와 60명의 정상인을 대상으로 하여 그들의 사고내용을 측정하였다. 이들의 사고내용은 불안민감성 척도(ASI), 광장공포인지 질문지(ACQ), 신체감각 질문지(BSQ)를 사용하여 측정되었다. 각 집단별 사고내용을 정밀하게 비교하기 위하여 각 척도의 개별문항에 대해서 차이비교검증을 실시하였다.본 연구의 주된 결과는 다음과 같다. 첫째, 공황 장애를 비롯해 불안장애 환자집단은 정상인 집단에 비해 세 척도에서 측정된 불안유발 사고내용을 현저하게 많이 가지고 있었다. 둘째, 공황장애 환자집단은 비불안 정신장애 환자(우울증 및 신체화) 집단에 비해 신체적 증상에 대해서 더 예민하고 이를 위협적인 것으로 평가하는 경향성이 있었다. 셋째, 공황장애 환자들은 비공황 불안장애 환자나 비불안 정신장애환자에 비해 극단적이고 파국적인 위험과 관련된 사고내용을 많이 가지고 있었다. 특히 공황장애 환자들은 다양한 신체적 증상과 변화에 예민하고 이를 죽음이나 통제상실상태와 같이 극단적이고 파국적인 것으로 해석하는 사고경향이 있는 반면, 비공황 불안장애 환자들은 대인관계에서의 부적절한 대처나 능력에 대한 부정적 평가와 같이 일반적이며 비파국적인 위험이나 위협과 관련된 사고내용을 많이 갖는 경향이 있었다.ABSTRACT The aim of the present study is to investigate some characteristics of patients with anxiety disorders in their thought contents from the theoretical perspective of the cognitive content-specificify hypothesis that cognitive contents influence emotional disorders. For this, differences in thought contents between patients with panic and non-panic anxiety disorder as well as between patients with anxiety disorders and non-anxiety psychiatric patients or nomal controls were examined.The data were collected from 92 psychiatric patients (34 panics, 24 non-panics, 34 non-anxiety psychiatric patients) and 60 normal controls. Their thought contents were measured with the Anxiety Sensitivity Inventory, Agoraphobic Cognition Questionnaire, and Body Sensation Questionnaire. The difference between groups in the individual item of the three measures was tested using ANOVA and multiple comparison tests.The main findings in the present study are as follows: First, the patients with anxiety disorders reported significantly more thoughts with anxiety-provoking contents than normal controls. Second, the patients with panic disorders tended to be more sensitive to physical symptoms and to interpret these as being threatening than the non-anxiety psychiatric patients. Third, the patients with panic disorder had more thoughts with contents related to extreme and catastrophic danger than those with non-panic anxiety disorders. In particular, those with panic disorder had strong tendency to be senstive to physical symptoms or changes and to interpret these as suggesting extreme and catastrophic danger such as death or loss of control, whereas those with non-panic anxiety disorders tended to have thoughts with contents related to general and non-catastrophic danger or threats such as inadequate coping in interpersonal situations or negative evaluation about their ability.

      • KCI등재
      • TILLING analysis using Brachypodium mutant induced by gamma irradiation

        Man Bo Lee,Dae Yeon Kim,Oon Ha Shin,Jin Seok Yoon,Sang Heon Kim,Woo Joo Jung,Yong Weon Seo 한국육종학회 2013 한국육종학회 심포지엄 Vol.2013 No.07

        Brachypodium has been focused as new model plant for grass species. Like small size, small room requirement, and fast growth, Brachypodium shows numerous advantages as a model plant. Brachypodium is a typical grass at the genome level, which also exhibits an overall similarity of gene content and gene families when compared with rice (Oryza sativa) and sorghum (Sorghum bicolor) genomes. Brachypodium is an excellent material for structural and functional genomic studies in grass species. Targeting-Induced Local Lesions IN Genomes (TILLING) is a high-throughput technique and an approach for reverse genetics study. Moreover, it has been wildly utilized to find induced mutation. Bradi3g45515 is orthologue of the cellulose synthase-like HvCslF8 in barley. For TILLING library construction, 384 M2 Brachypodium mutants induced by chronic-gamma irradiation were used. Single nucleotide polymorphysm (SNP) and small deletion in Bradi3g45515 were searched through TILLING analysis. Template DNA for PCR reaction were prepared according to two dimensional pooling (eightfold) strategy. Heteroduplex DNA was digested by SURVEYOR nuclease (TRANSGENOMIC) and the DNA fragment was detected using polyacrylamide gel electrophoresis. Positive signal appeared at polyacrylamide gel from more than 4 lines and their Bradi3g45515 region were sequenced. SNP(s) were identified in 509-2 and 677-3 mutant line. Cellulose content and/or cell wall materials content will be measured using these mutants.

      • KCI등재

        Prediction of climate change effects on the potential distribution of cycad blue butterfly (Luthrodes pandava) in South Korea

        Shin Man‐Seok,Kim Tae‐Geun,Cho Youngho 한국곤충학회 2022 Entomological Research Vol.52 No.12

        Luthrodes pandava (Lepidoptera: Lycaenidae) is a major pest of the genus Cycas (Cycadales: Cycadaceae) and mainly inhabits low latitudes of Asia. Recently, L. pandava has gradually spread to other regions. L. pandava was first recorded in South Korea in 2006 and has been continuously observed on Jeju Island ever since. Adequate management and mitigation plans are necessary to prevent further spread of L. pandava throughout Korea. Therefore, this study used a species distribution model to predict the potential distribution of L. pandava under current and future climate conditions. A weighted ensemble model that incorporated the accuracy of 10 species distribution models was used to improve the forecast certainty. The potential distribution areas of L. pandava were predicted in units of 20 years from the present to 2,100 using a climate change scenario (SSP5–8.5). Under current and future climate conditions, the ensemble model predicted that L. pandava would be extensively distributed on Jeju Island and along the southern seaboard, west coast, and east coast, inhabiting 50–70% of Korea’s land area by 2,100. Additionally, many sources of food for L. pandava, excluding those in the Cycas genus, have been observed in Korea. Thus, trading ports and the inland of the Korean Peninsula must be continuously monitored for outbreaks of L. pandava. The findings of this study provide essential necessary data to help mitigate the outbreak and spread of L. pandava in Korea and their associated damage to the Cycas genus.

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