外來患者 및 돼지에서의 間接Latex凝集反應法에 依한 Toxoplasma 抗體價 調査硏究

심희숙,나영언,이영하,신대환 충남대학교 의과대학 지역사회의학연구소 1991 충남의대잡지 Vol.18 No.2

This study was undertaken to konw the sero-epidemiologic meanings of toxoplasmosis by Indirect Latex Agglutination test of 514 general outpatients and 100 pigs. The results were obtained as follows: 1. Toxoplasma antibody titers were showed as 418 negative cases(81.3%), 63 cases(12.2%) in a titer of 1:16, 20 cases(3.9%) in a titer of 1:32, 8 cases(1.6%) in a titer of 1:64, 3 cases(0.6% ) in a titer of 1:128 and 2 cases(0.4%) in a titer of 1:256, respectively. 2. Antibody titer was somewhat declined to the nineteen ages (from 6.1% to 3,0%) but was increased from twenty to fifty-nine ages(from 9.1% to 24.2%). The positive percentage of Toxoplasma antibody titers were the highest as 24.2% in the fifties group. Totally, 33 cases(6.5%) among 514 patients was showed as positive reaction. 3. According to the sex group, 16 cases of the male and 17 cases of the female were showed as positive reaction 5.6%, 7.5%, respectively. Positive rates of the female was somewhat higher than that of the male. 4. Antibody titers of sera of the pig were shown as 65 negative cases(65%), 24 cases in a titer of 1:16(24%), 6 casesin 1:32(6%), 3 cases in 1:64(3%) and 2 cases in 1:1.28(2%), respectively . Totally, positive rates was 11%.

효소결합 면역분석법을 이용한 결핵진단의 유용성에 관한 연구

심영수,김종숙 중앙대학교 의과대학 의과학연구소 1984 中央醫大誌 Vol.9 No.2

Enzyme-linked immunosorbent assay was done on 106 patients with tuberculosis and 30 normal persons using Tubercle bacilli Extract Antigen(TE antigen) and PPD Antigen. Following results are obtained. 1. With TE antigen the absorbance of antibody titer was 0.315±0/245 in miliary tuberculosis; minimal, 0.228±0.167; moderately advanced, 0.556±0.616; far advanced 1.116±0.651, and 0.126±0.084 in normal control. 2. With PPD antigen the absorbance of antibody titer of miliary tuberculosis was 0.227±0.142; minimal, 0.212±0.086; moderately advanced, 0.527±0.515; far advanced, 0.954±0.612 and normal, 0.199±0.086. 3. There was strong correlation between TE antigen and PPD antigen with correlation coefficient of r=0.888 (p<0.001). 4. Antibody titer was higher in tuberculosis than normal control and there was correlation between the antibody titer and the severity of disease.

Interferon-gamma 투여에 의한 Toxoplasma 감염 마우스의 면역학적 변화

이영하,신대환,심희숙 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.1

This study was performed to evaluate differences of immune responses according to the injection period of recombinant mouse interferon-γ(IFN-γ) in acute murine toxoplasmosis. Each mouse was infected intraperitoneally with 100 cysts of Beverley strain of T. gondii, and injected with 5 × 10 ^4 units of IFN-γ every other day for a total of two injections. From the 1st week after infection, blastogenic responses of splenocytes to concanavalin A(Con. A, 2.5㎍/ml) and Toxoplasma antigen(30.0㎍/ml) were examined at 1 week interval for 4 weeks. Also serum IgG and IgM antibody titers were examined by enzyme-linked immunosorbent assay, and immunohistochemical study of brain tissues were done at the same time. Toxoplasma antigen-treated blastogenic responses were significantly increased in the IFN-γ injected groups as compared with Toxoplasma-infected group. However Con. A-treated blastogenic responses were increased in the mice that received two doses of IFN-γ on day 4 and 2 before infection, or day 2 and 0 before infection. The serum IgG and IgM antibody titers of IFN-γ injected groups were increased from 2 weeks after infection, and IgM antibody titers were increased at 2 and 3 weeks after infection as compared with non-infected group. No significant differences were revealed between IFN-γ injected groups and Toxoplasma-infected group. T gondii was found as tachyzoites at 2 weeks after infection, and cysts found in 4 weeks. However, no T. gondii was detected in IFN-γ injected groups in the same period. The results suggested that IFN-γ administration to T. gondii-infected mice improve the cell-mediated immune responses, especially when IFN-γ was injected just before T. gondii infection. But there was not significant differences serum antibody titers and immunohistochemical findings of brain tissues according to the injection period of IFN-γ.

유아교사의 정보통신기술 (ICT)활용의 교사신념

김미은,심숙영 숙명여자대학교 아동연구소 2005 兒童硏究 Vol.18 No.1

The purpose of this study attempted to examined the application level of early childhood teachers' ICT(information and communication technology), who took charge of role to be important for ICT application of early childhood field, and to know relation of their educational beliefs according to the levels. For these purpose, a questionnaire was distributed to 141 teachers of kindergartens and child care centers located at Seoul and Kyo?nggi, to ask how they applies ICT and examine the relation between their ICT level and their educational beliefs. The results of this study are as follows; First, Using information and communication technology, teachers can not apply that as an improvement of individual education method but can do a basic application, for example knowledge acquirement. The average application level was 3.60 for early childhood teachers. Result showed that an association between the application level of ICT and early childhood teacher's education level, application lever of ICT was associated with teacher's age and training experience related ICT, positively and negatively. Second, On the analysis of application level of early childhood teachers' ICT and educational beliefs, there was a significant positive association between maturationism and cognitivism among educational beliefs and the application level of ICT.

일반 동화와 인터넷 동화가 유아발달에 미치는 영향에 대한 부모의 인식 비교

심숙영,차은경 숙명여자대학교 아동연구소 2005 兒童硏究 Vol.18 No.1

A purpose of this study is going to watch a difference of the recognition parents have on a language, a society, emotion, a creative thinking development according to children's story delivery media. The study object is parents of parents of the infant who uses mainly a general children's story and the infant who use mainly Internet children's story. And be going to look into difference of recognition about as influence to reach to a development of an infant according to an intervention degree of parents. This study results, as for the parents who use mainly a general children's story, 'speaking' and 'analogy anger' have the recognition that affected a development. And the parents who were utilized mainly listened to Internet children's story 'social phenomenon and development of environment' and 'originality' have the recognition that affected a development. Also, generally dirt to select Internet children's story aggressive intervention of parents has the recognition that played an influence in a development of an infant.

미용업소의 내부마케팅과 보상지각이 직무만족 및 조직성과에 미치는 영향

정형식,이재숙,김영심 朝鮮大學校 2003 經營經濟硏究 = Management and economics research Vol.26 No.1

후지 사과 Polyphenol Oxidase 의 특성 및 활성억제

최언호,정동선,조남숙,심영현 한국농화학회 1987 Applied Biological Chemistry (Appl Biol Chem) Vol.30 No.3

As a basic research for inhibition of enzymatic browning of apples during dehydration or processing, polyphenol oxidase was extracted from Fuji apples to investigate heat inactivation, chemical inhibition and other properties. Polyphenol oxidase showed the highest activity at 20℃ and pH 5.5 with catechol as substrate, and the Michaelis constant of 0.14 M under the same condition of substrate and pH. The thermal inactivation followed pseudo first-order kinetics to have activation energy of 23.0 k㎈/㏖ and z value of 19.7℃. As for substrate specificity the polyphenol oxidase showed high affinity toward the o-diphenolic compounds, particularly chlorogenic acid. Neither the m- and p-dihydroxy phenols nor monophenols were attacked. Browning by polyphenol oxidase was completely inhibited at the concentrations of l0mM for potassiummetasulfite and thiourea and 1mM for L-cysteine, ascorbic acid and sodium diethyldithiocarbarnate.

애착유형에 따른 영유아의 정서지능 및 사회 지능 간의 구조분석

심숙영 ( Young Sook Shim ) 한국아동교육학회 2013 아동교육 Vol.22 No.4

본 연구에서는 영유아 애착유형을 안정애착과 불안정 애착으로 분류하여 정서지능과 사회지능의 관련성을 조사하고, 애착유형과 사회지능 간의 정서지능의 매개역할을 분석하였다. 연구결과 첫째, 안정애착을 보일수록 정서지능이 높았고, 이는 사회지능의 사회지식, 사회표현성, 사회유연성이 높아지는 결과로 이어진 반면, 불안정애착을 보일수록 전서지능이 낮았도, 이는 사회지능의 사회지식, 사회표현성, 사회유연성이 낮아지는 결과로 이어졌다. 이러한 결과는 정서지능이 안정애착과 사회지능, 불안정애착과 사회지능 사이에서 완전매개효과를 가지는 것을 보여준다. 둘째, 정서지능은 사회지능과 직접적인 효과가 유의미하게 나타나 정서지능이 높을수록 사회지능의 사회지식, 사회표현성, 사회유연성이 높은 것으로 나타났다. 이러한 결과들은 애착유형, 정서지능과 사회지능 간의 인과관계를 밝히고, 애착유형과 사회지능 간의 전서지능 매개효과를 경험적으로 입증하였다. The purpose of this study was examined the relationship between attachment, emotional intelligence, and social intelligence, and the mediating role of emotional intelligence between them. Two hundred and eighteen young children of 12-38 months in child care centers were participated in this study. Results showed that the young children of secure attachment were more likely to show better the emotional intelligence, which in turn promoted social intelligence. Whereas the young children of insecure attachment were more likely to less the emotional and social intelligence. Also the links between attachment and social intelligence were fully mediated by emotional intelligence. These findings suggest that secure attachment relationship to parents foster social intelligence by promoting high levels of emotional intelligence.

Effects of Different Application Rates of Organic Compound Fertilizer on Young Squash Growth and Soil Chemical Properties under Plastic Film House

Myung Sook Kim,Seong Jin Park,Sung Hyun Kim,Hyun Young Hwang,Jae Hong Shim,Yun Hae Lee 한국토양비료학회 2020 한국토양비료학회지 Vol.53 No.3

To determine the replacement ratio of organic compound (OC) for basal application of inorganic fertilizers,the effects of different rate of OC on young squash (Cucurbita moschata) plant growth and soil chemicalproperties of plastic film house were investigated. The OC were applied at 50% (OC50+N50), 100%(OC100), and 150% (OC150) as the basal amount of inorganic nitrogen fertilizer recommended by soilfertility test, and the treatment were compared with inorganic NPK and PK treatment. The yield of youngsquash in OC150 treatment was similar to NPK treatment and higher than PK. In OC50+N50, OC100, andOC150 treatments, nitrate concentration and electrical conductivity (EC) were similar to NPK treatment. Relative nitrogen use efficiency of young squash ranged 17~37%. These results suggest that OC applicationas the basal dressing at the 150% level could be best rate to minimize nutrient accumulation of soil and toensure the yield of young squash. Further study is required to evaluate effect of long-term application of OCon soil sustainability and young squash productivity

사회적 지지, 어머니의 심리적 안녕감, 애착유형과 영유아의 사회정서유능성 및 문제행동 간의 구조적 관계

심숙영 ( Sook Young Shim ) 한국아동교육학회 2016 아동교육 Vol.25 No.1

본 연구에서는 영유아기 자녀를 둔 어머니와 영유아를 대상으로 사회적 지지와 어머니의 심리적 안녕감과 애착유형이 영유아의 사회정서행동(사회정서유능성, 문제행동)에 영향을 미치는 경로를 분석하였다. 본 연구에는 서울시 소재의 영아전담 어린이집에 다니는 12-43개월의 205명 영유아와 그들의 어머니가 참여하였다. 연구결과를 살펴보면, 첫째, 사회적 지지는 어머니의 심리적 안녕감에 직접적으로 영향을 미치는 경로로 나타났다. 둘째, 애착유형은 어머니의 심리적 안녕감과 영유아의 사회정서행동(사회정서유능성, 문제행동) 간에 매개역할을 하고 있는 것으로 나타났다. 셋째, 사회적 지지는 어머니의 심리적 안녕감에 영향을 미쳤고, 어머니의 심리적 안녕감은 자녀와의 애착유형에 영향을 미쳤으며, 이는 다시 애착유형을 매개로 영유아의 사회정서행동(사회정서유능성, 문제행동)에 영향을 미치는 경로로 나타났다. The purpose of this study was to examine the structural relationships among social support, maternal psychological well-being, attachment style and young children``s social-emotional behaviors(competence and behavior problem). 205 mothers and children from 12 to 43 months in child care centers were participated and their responses were analyzed using structural equation models. Results indicated the following. First, social support had influenced directly on psychological well-being of mothers. Second, psychological well-being of mothers had influenced directly on secure attachment style. Third, attachment style had direct influence on children``s social-emotional behaviors(competence and behavior problem). Finally, maternal psychological well-being and attachment style had a mediation effect on the relationship between social support and children``s social-emotional behaviors outcomes(competence and behavior problem). These results shows clearly the paths in which social support, maternal psychological well-being, secure attachment style are closely related each other as well as the relationship is connected to young children``s social-emotional behaviors(competence and behavior problem).