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      • SCOPUSKCI등재

        경북 성주지역 장수노인의 계절별 식품섭취 상태

        백지원(Ji-Won Baek),구보경(Bo-Kyung Koo),김규종(Kyu-Jong Kim),이연경(Yeon-Kyung Lee),이성국(Sung-Kook Lee),이혜성(Hye-Sung Lee) 한국식품영양과학회 2000 한국식품영양과학회지 Vol.29 No.4

        본 연구는 우리나라 장수노인들의 식품섭취상태를 분석 평가하고 건강한 장수를 위한 식생활 지침의 설정을 위한 기초자료를 얻고자 수행되었다. 연구 대상은 경상북도 성주군에 거주하는 85세 이상 고령노인 중에서 일상 생활에 문제가 없는 224명이었으며 이들을 대상으로 반복 24시간 회상법을 이용하여 1년간 4회의 계절별 식품 섭취 조사를 실시하였으며 결과를 요약하면 다음과 같다. 계절별 식품군별 섭취량에 있어서 남자노인은 감자류의 섭취량이 여름철에 유의적으로 높고, 버섯류의 섭취량이 가을철에 유의하게 높은 것을 제외하고는 모든 식품군의 섭취량에 있어 계절별 차이가 나타나지 않았다. 여자노인의 경우 곡류, 당류, 두류, 채소류, 과일류, 조미료류, 음료 및 주류, 육류, 우유류, 어패류의 섭취량이 겨울철에 유의하게 높았으며, 종실류, 해조류, 난류의 섭취량은 계절에 따른 차이가 없었다. 조사 대상자들의 연평균 1일 총 식품 섭취량은 594.4±186.1 g이었으며 이 중에서 513.5±161.2 g(86.4%)는 식물성 식품군으로부터 섭취하였고 79.3±56.7 g(13.3%)는 동물성 식품군으로부터 섭취하였다. 섭취량이 가장 높았던 식품군은 곡류였으며그 다음이 채소류, 과일류, 어패류, 음료 및 주류, 조미료류, 두류, 육류, 우유류, 감자류 등의 순이었다. 장수 노인대상자들의 음식별 섭취빈도는 밥류에 있어서는 쌀밥의 섭취비율이 80.1~89.2%로 가장 높았으며 국과 찌개류에서는 쇠고기국, 된장국, 된장찌개의 섭취 비율이 높았다. 어육류 식품의 경우 조기구이의 섭취비율(9.4~12.7%)이 높았으며, 해조류 식품의 경우 김구이의 섭취비율(7.4~20.5%)이 높았고, 각 계절마다 계절식품의 섭취비율이 높았다. 김치류의 경우 배추김치의 섭취비율이 4계절 모두 70% 이상으로 높게 나타났다. 일품요리류는 손쉽게 조리할 수 있는 라면과 국수의 섭취비율이 높았다.<br/> 본 연구의 결과에서 경북 성주지역 장수 노인들의 계절별 식품 섭취량에 있어 겨울철의 식품 섭취량이 다른계절에 비해 유의하게 높았으며, 남자노인보다는 여자노인이 식품섭취에 계절에 의한 영향을 더욱더 많이 받는 것으로 나타났다. 또한 장수 노인들은 가공식품보다는 계절마다 제철에 생산되는 자연 식품의 섭취비율이 높았다. 전반적으로 장수노인들은 소식의 경향을 보였으며 이와 같은 소식습관과 신선한 식물성 식품들의 일상 섭취가 건강한 장수에 영향을 미쳤을 가능성도 있을 것으로 사료된다. The purpose of this study was to estimate food intakes of the long-lived elderly and to obtain the data for establishing dietary guidelines that may be recommended for the general population for the sake of longevity. The subjects of the study were 224 elderly people of age over 85 years living in Kyungpook Sung-Ju area who have no problem in daily living. The food consumption survey was carried out seasonally by the repeated 24-hr recall method for one year. The subject group for this study was composed of 58 males and 166 females, the average age being 87 years old. Food intakes of the winter were more than any other seasons. The mean daily total food intake per capita was 594.4 g, 513.5 g (86.4%) from plant foods and 79.3 g (13.3%) from animal foods. The sequence of high intakes of food groups were cereals, vegetables, fruits, fishes, legumes and meats. Boiled white rice, beef soup, soybean paste soup, soybean paste stew, broiled yellow croaker, kimchi, ra myon and broiled noodles were consumed most frequently. In conclusion, the subjects consumed much more plants foods than animal foods and consumed more natural and seasonal foods than processed foods and also showed food habits of eating small meals. Dietary habits of eating small meals containing abundant amount of fresh plant foods might partially contribute to the longevity of the subjects.

      • SCOPUSKCI등재
      • SCOPUSKCI등재

        숙잠 함유 복합물의 알코올 대사 및 숙취개선 효능평가

        우미선(Miseon Woo),차지현(Ji Hyeon Cha),김용환(Yonghwan Kim),강희택(Hee-Taik Kang),김현덕(Hyeondok Kim),조경원(Kyong Won Cho),박성선(Sung Sun Park),이종훈(Jong Hun Lee) 한국식품과학회 2021 한국식품과학회지 Vol.53 No.1

        숙취를 해결하기 위해서는 숙취를 직접적으로 유발하는 물질인 아세트알데하이드의 조절이 가장 중요한 인자로 작용한다. 숙잠을 함유하는 복합물인 시험식품(CKDHC)의 섭취로 혈중 아세트알데하이드 농도가 대조식품 대비 통계적으로 유의하게 감소하여 숙취개선 효능을 확인하였다. 특히, 30분부터 각 시간별(mg/L), 혈중 아세트알데하이드 농도-시간곡선하 면적(AUC), 최고 혈중 아세트알데하이드 농도(C<SUB>max</SUB>)의 감소를 통해 30분부터 빠른 숙취개선 효능을 확인하였다. 본 연구의 주원료로 사용된 숙잠은 Ji등(2016a)에 따르면 18종의 아미노산 및 무기질을 모두 함유하며, 고단백 식용곤충으로 간에 좋은 주요 아미노산인 Alanine, Arginine 등을 많이 함유하여 간의 효소활성에 긍정적인 영향을 줄 수 있음을 알수있다. 본 연구결과를 통해 숙잠을 함유하는 시험식품이 숙취해소제로 작용할 수 있으며, 특히 음주 전 섭취시 아세트알데하이드를 빠르게 분해하여 30분부터 숙취 개선에 효과가 있음을 입증하였다. Silkworms have traditionally been used to produce silk and textiles. However, steamed and freeze-dried mature silkworm larval powder (SMSP) contain large amounts of amino acids, vitamins, and essential minerals. In this study, we investigated the potential of SMSP as a hangover-relieving agent. Thirty individuals who met the selection criteria and exclusion criteria were included in the study and subsequently underwent a double-blind, randomized, placebo-controlled, cross-design human application test. Importantly, the test product containing SMSP (CKDHC) was proven to alleviate hangovers through a significant reduction in the plasma concentration of acetaldehyde in the context of an alcohol-induced hangover model. In particular, from 0.5 h after SMSP intake, the blood acetaldehyde concentration (mg/L), area under the time curve (AUC; indicating the degree of bioabsorption of blood acetaldehyde), and the highest blood acetaldehyde concentration (Cmax) were reduced. Altogether, these results suggest that the test product (CKDHC) exhibits an accelerated hangover-relieving effect.

      • KCI등재

        부산.경남지역의 일부 고등학교 교사들의 물리치료에 대한 인식도 조사

        김지원,박상현,주성희,김용권,안덕현,Kim, JI-Won,Park, Sang-Hyeon,Joo, Sung-Hui,Kim, Yong-Kwon,Ahn, Duck-Hyun 대한물리치료과학회 2003 대한물리치료과학회지 Vol.10 No.2

        This study randomly chose 10 humanity high schools, which are located in Busan and KyoungNam province. We then examined the recognition rate of physical therapy among 378 teachers who were and still are working in the schools. 1. The recognition grade of physical therapeutics between men and women was significantly different with results of 80.7% of men and 69.7% of women(p<0.05). In the case of experiencing physical therapy, 83.6% of people said they knew the physical therapeutics and in the case of the opposite side, the result was also significantly different with a result of 67.8%(p<0.05). 2. We ranked the people on how much they knew about the physical therapeutics among men and women. With men, the actual experience of physical therapeutic came before what they heard from other people. In the case of women, what they heard from other people came first and the actual experience of physical therapeutic came after. According to the public information from Inje University, the recognition grade is recorded in the 3rd grade department as 21.5% while in the case of experiencing treatment from a physical therapist, the result was 39.1%. In the other department (the 1st grade department), what men and women heard from mass media was recorded at 17.5% and what they heard from other people, it was recorded at 33.8%(p<0.05). 3. The research about the recognition of academic ability of being a physical therapist was that 55.6% of teachers thought that 3-year-college was the best, which made the results different from the recognition grade of the experience of education(p<0.05). 4. In the recognition grade of physical therapeutics, there were significantly differences from 50.2% of men and 45.2% of women were expecting about 1mil ion won to 1.99million won. In case of 25.2% of people who have experience less than 15years at work, they expected about 2million to 2.99million won. The figures were higher than 10.1% of people who have experiences over 15years. About the recognition grade of physical therapists social level in the future is 48.8% of people who had experienced of physical therapy and 63.8% of people who never had experienced of it said it would be better in the future. From these results, the recognition about physical therapeutics and the view of its social status are optimistic and they know well about the level of academic ability of physical therapists. On the other hand, most teachers don't know exactly about physical therapists work. So we have to inform them aggressively for enhancing the recognition of physical therapy because high school students are well affected by their teachers when they face their future or major in university.

      • SCOPUSKCI등재

        Single and Five-Week Oral Dose Toxicity Studies of Calcitriol and Alendronate Mixtures in Rats

        Sung Won Moon,Ji Yun Lee,Jin Hee Lee,Sang Soo Sim,Chang Jong Kim 한국독성학회 2004 Toxicological Research Vol.20 No.3

        The purpose of this study was to assess the single and 5 week oral dose toxicity of<br/> calcitriol and alendronate combination (1 : 10,000) treatment for osteoporosis or Paget's disease in<br/> male and female rats. In single dose oral toxicity study, the values of LD50 of calcitriol and alendronate<br/> mixture were 750.075 mg/kg in male rats and 775.0775 mg/kg in female rats, respectively.<br/> Body weight and food consumption were continuously increased after adminstration of calcitriol and<br/> alendronate mixtures, and there was no significant changes in body weight and food consumption in<br/> all groups. In five-week oral toxicity study of calcitriol and alendronate mixture at a dose of 0.2 μg +<br/> 2 mg, 1 μg + 10 mg, 5 μg + 50 mg and 25 μg + 250 mg, respectively, there was no mortality,<br/> abnormal behavior and appearance in all groups throughout the administration period (5 weeks) and<br/> recovery period (2 weeks). Dose-dependent changes in parameters of urinalysis and hematological<br/> analysis were not observed in male and female rats treated with calcitriol and alendronate mixtures.<br/> All the values of the parameters appeared to be in the normal range. These data indicate that both<br/> calcitriol and alendronate are drugs having low toxicity in rats. NOAEL of calcitriol and alendronate<br/> mixtures were 50.005 mg/kg in 5-week oral toxicity.

      • S-241 Serum Adipocyte-Specific Fatty Acid-Binding Protein is a Predictable Marker of CAD and DM

        ( Ji-hye Min ),( Won-yong Shin ),( Sang-ho Park ),( Se-whan Lee ),( Seung-jin Lee ),( Dong-kyu Jin ) 대한내과학회 2016 대한내과학회 추계학술대회 Vol.2016 No.1

        Introduction:?Adipocyte-specific fatty acid-binding protein (A-FABP), expressed in adipocytes and macrophages, plays a central role in the development of atherosclerosis and diabetes mellitus in experimental animals. We assessed hypothesis that A-FABP is also plays a central role in the development of atherosclerotic cardiovascular disease and DM in humans.?Methods:?In a total of 175 Korean adult, in whom CAG were performed, anthropometrical and biochemical parameters were measured. Serum A-FABP levels were measured using ELISA. The metabolic syndrome was diagnosed according to American Heart Association/National Heart, Lung and Blood Institute.?Results:?136 subjects (77.2%) had coronary artery disease (CAD) and 61 subjects (34.9%) had DM. Serum A-FABP level in CAD patients is showned significantly higher than in non-CAD patients (46.75±17.79 ng/mL vs. 26.75±9.48 ng/mL, p<0.001). Serum A-FABP level in DM and metabolic syndrome patients is also showed significantly higher than in non-diabetic and non-metabolic syndrome patients. In addition, serum A-FABP level in CAD patients is showed significantly higher than in non-CAD patients after adjustment for sex, age, DM and metabolic syndrome (p=0.035). And serum A-FABP level in diabetic patients is also showed significantly higher than in non-diabetic patients after adjustment for sex, age, CAD and metabolic syndrome (p<0.001).?Conclusions:?Serum A-FABP might be a predictable marker of CAD and DM in Korean adults.

      • SCOPUSKCI등재

        Intracellular Reactive Oxygen Species (ROS) Removal and Cytoprotection Effects of Sweet Potatoes of Various Flesh Colors and Their Polyphenols, Including Anthocyanin

        Ji Hae Lee,Koan Sik Woo,Hyeong-Un Lee,Sang Sik Nam,Byong Won Lee,Yu-Young Lee,Byoungkyu Lee,Hyun-Joo Kim 한국식품영양과학회 2019 Preventive Nutrition and Food Science Vol.24 No.3

        The flesh color of sweet potatoes varies based on the antioxidant pigments in the cultivar. In this study, the antioxidant characteristics of various flesh color sweet potato cultivars (Jinyulmi, Juhwangmi, Pungwonmi, and Sinjami) were investigated. The polyphenol contents were highest in the purple-fleshed cultivar, Sinjami (39, 68, and 71㎍ gallic acid equivalent/g in distilled water, fermented ethanol, and ethanol extracts, respectively). The Sinjami cultivar contained 29 mg/100 g of anthocyanin, which is the major component resulting in increased concentrations of polyphenols. Using 2,2’- azinobis(3-ethylbenzothiazoline-6-sulphonic acid), 2,2-diphenyl-1-picrylhydrazyl, and ferric reducing ability of plasma assays, Sinjami showed greater antioxidant activity than the other cultivars. Additionally, the Sinjami extracts could recover cellular reactive oxygen species levels in tert-butyl hydroperoxide-stimulated HepG2 cells to a normal level. In conclusion, anthocyanin-enriched Sinjami has strong antioxidant activities and could improve health by suppressing oxidative damage.

      • KCI등재

        Comparative Immediate Effects of Isometric Chin-tuck and Dynamic Neuromuscular Stabilization on Neck Flexor Muscle Thickness and Upright Sitting Height Posture

        Ji-won Shin,Hyun-sik Yoon,Ji-ho Park,Ha-yeon Kim,Joshua(Sung) H. You 한국전문물리치료학회 2019 한국전문물리치료학회지 Vol.26 No.4

        Background: Cervical dysfunction is a common pathomechanical marker in individuals with forward head posture (FHP). To overcome the limitations of the isometric chin-tuck (ICT) exercise, dynamic neuromuscular stabilization (DNS), which emphasizes an entire spinal chain exercise, has recently shown promising clinical results. Objects: Purpose of this study was to compare the immediate effects between ICT and DNS techniques. Methods: 43 young subjects (mean age, 24.0±5.0 years) were recruited. Group of subjects with FHP were measured under baseline, ICT, and DNS conditions. Outcome measures included sitting height, longus colli (LC) and sternocleidomastoid (SCM) muscle thickness and LC/SCM thickness ratio. One-way repeated measures ANOVA was used to compare the continuous dependent variables among FHP, ICT, and DNS conditions at p<.016. Results: Both ICT and DNS exercise conditions yielded significantly increased LC muscle thickness, LC/SCM thickness ratio and sitting height than did FHP condition (p<.0001, respectively). Sitting height was significantly greater in DNS exercise than in the ICT exercise (p<.0001). Conclusion: The present results demonstrated that sitting height was greater in the DNS exercise than in the ICT exercise, as well as both corrective postural training exercises were effective on LC/SCM muscle balance ratio when compared with the baseline FHP condition. Therefore, it is considered that DNS exercise can be the recommended exercise for people with FHP.

      • KCI등재

        Characterization of Itraconazole Semisolid Dosage Forms Prepared by Hot Melt Technique

        Sang-Young Shim,Chang-Won Ji,사홍기,박은석,이범진 대한약학회 2006 Archives of Pharmacal Research Vol.29 No.11

        The objective of this study was to formulate itraconazole semisolid dosage forms and characterize their physicochemical properties. Itraconazole and excipients such as polysorbate 80, fatty acids, fatty alcohols, oils and organic acids were melted at 160oC. The fused solution was then cooled immediately at -10oC to make wax-like semisolid preparations. Their physicochemical attributes were first characterized using differential scanning calorimetry, Fourier transform infrared spectroscopy and nuclear magnetic resonance spectrometry. The solubility of itraconazole in semisolid preparations and their dispersability in the simulated gastric fluid were also determined. Our semisolid preparations did not show any distinct endothermic peak of a crystalline form of itraconazole around 160-163oC. This suggested that it was changed into amorphous one, when it was formulated into semisolid preparations. In addition, the distinctive functional peaks and chemical shifts of itraconazole were well retained after processing into semisolid preparations. It could be inferred from the data that itraconazole was stable during incorporation into semisolid preparations by the hot melt technique. In particular, itraconazole semisolid preparations composed of polysorbate 80, fatty acids and organic acids showed good solubility and dissolution when dispersed in an aqueous medium. It was anticipated that the semisolid dosage forms would be industrially applicable to improving the bioavailability of poorly water-soluble drugs.

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