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Severe Adverse Events of Periocular Acupuncture: A Review of Cases
Sang-Mok Lee(Sang-Mok Lee),Jun Wu(Jun Wu),Daniel Duck-Jin Hwang(Daniel Duck-Jin Hwang ) 대한안과학회 2023 Korean Journal of Ophthalmology Vol.37 No.3
Acupuncture is recognized as a component of alternative medicine and is increasingly used worldwide. Many studies have shown the various effects of acupuncture around the eyes for ophthalmologic or nonophthalmologic conditions. For ophthalmologic conditions, the effect of acupuncture on dry eye syndrome, glaucoma, myopia, amblyopia, ophthalmoplegia, allergic rhinoconjunctivitis, blepharospasm, and blepharoptosis has been reported. Recently, several studies on dry eye syndrome have been reported and are in the spotlight. However, given the variety of study designs and reported outcomes of periocular acupuncture, research is still inconclusive, and further studies are required. In addition, although a systematic and reliable safety assessment is required, to the best of our knowledge, there have been no reports of a literature review of ocular complications resulting from periocular acupuncture. This review collected cases of ocular injury as severe adverse events from previously published case reports of periocular acupuncture. A total of 14 case reports (15 eyes of 14 patients) of adverse events published between 1982 and 2020 were identified. This review article provides a summary of the reported cases and suggestions for the prevention and management of better visual function prognosis.
( Sang Hee Lee ),( Min Ji Kim ),( Eun Jung Jo ),( Jung Seop Eom ),( Jeong Ha Mok ),( Mi Hyun Kim ),( Ki Uk Kim ),( Hye Kyung Park ),( Min Ki Lee ),( Kwang Ha Lee ) 대한결핵 및 호흡기학회 2014 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.118 No.-
Background: Currently, patients requiring ventilator care for more than 96 h are defined as undergoing prolonged acute mechanical ventilation (PAMV), and the number of such patients is expected to increase. We evaluated the clinical factors related to a poor prognosis by analyzing patients requiring PAMV in the medical intensive care unit (ICU) of a university-affiliated tertiary care hospital in Korea. Methods: We retrospectively analyzed data collected from March 2008 to February 2013. During the study period, 311 patients (41%) were categorized as on PAMV. We analyzed the prognostic factors on day 28 using clinical data gathered from the medical records on day 4 of mechanical ventilation (MV). Results: The median age of the enrolled patients was 67 [interquartile range (IQR) 59-75] years and 223 (71.7%) were male. The 28-day mortality rate after ICU admission was 34.7%. The most common underlying comorbidity was chronic lung disease (31.5%). The median ICU and hospital stays were 15 (IQR 9-27) and 26 (IQR 15-50) days, respectively. The median Acute Physiology and Chronic Health Evaluation and Sequential Organ Failure Assessment scores on the admission day were 17 (IQR 13-21) and 5 (IQR 3-6), respectively. Four variables on day 4 of MV (neuromuscular blocker required [hazard ratio (HR) 2.432, 95% confidence interval (CI) 1.337-4.422; p=0.004], vasopressor required [HR 2.312, 95% CI 1.258-4.248; p=0.007], hemodialysis required [HR 1.913, 95% CI 1.018-3.595; p=0.044], and body mass index = 21 [HR 1.827, 95% CI 1.015-3.288; p=0.044]) were independent factors associated with mortality based on a Cox proportional hazards model that excluded patients (n=12) with a do-not-resuscitate order given before day 4. Conclusions: Four clinical factors on day 4 of MV appear to indicate a poor prognosis in patients with PAMV: vasopressor required, neuromuscular blocker required, hemodialysis required, and body mass index = 21.
( Sang Mok Lee ),( Mee Kum Kim ),( Jae Lim Lee ),( Won Ryang Wee ),( Jin Hak Lee ) 대한안과학회 2008 Korean Journal of Ophthalmology Vol.22 No.1
Purpose: To report 2 cases of Comamonas acidovorans keratitis in immunocompromised cornea. Methods: A complete review of the medical records of the two cases of Comamonas acidovorans keratitis. Results: We found some similarities in clinical courses of two cases. Both of them showed development of keratitis during the management with corticosteroids, delayed onset, slow response to antibiotics, and relatively less affected corneal epithelium. Conclusions: Comamonas acidovorans is known as a less virulent organism. However it can cause an indolent infection that responds slowly even to adequate antibiotics therapy in immunocompromised corneas. Korean Journal of Ophthalmology 22(1):49-52, 2008