기포탑 내의 중금속 수용액에 대한 기-액접촉면적과 물질전달에 관한 연구

한승완,김상렬,윤영웅 東亞大學校 1992 東亞論叢 Vol.29 No.1

기포탑 내에서 중금속 수용액에 대한 기체 체류량, 기포경, 기-액 계면적 및 액상 용량물질 전달계수를 용액의 물성과 분산판의 종류에 따라 실험하였다. 기체 체류량, 기-액 계면적 및 액상 용량 물질 전달계수는 기체 속도와 용액의 농도가 증가함에 따라 증가하는 경향을 보였다. 기포경은 용액의 농도가 증가하면 감소하였고 기-액 계면적과 기체 체류량 사이에는 직선 관계를 나타내었으며, 기체 체류량과 액상용량물질전달계수에 대한 새로운 무차원식을 구하였다. In the experiment of heavy metal solution in the bubble column, gas hold up, bubble diameter, gas liquid interface area and volumetric liquid phase mass transfer coefficient are measured according to liquid properties and various perforated plates. Gas hold up and gas liquid interface area increase as the gas velocity and liquid concentration increase. Bubble diameters decrease as the liquid concentra-tions increase. The gas liquid interface areas are directly proportional to the gas hold up. The new dimensionless correlations of gas hold up and the volumetric mass transfer coefficients are obtained.

지방정부의 정보기술이용 활성화 방안 : 한국과 미국의 비교연구 A Comparative Study of Korea and the U.S.

한상연 경희대학교 사회과학대학 1998 社會 科學 論叢 Vol.16 No.-

삶의 질 향상을 위한 도시문화의 재발견

한상연,신영산 경희대학교 사회과학대학 1999 社會 科學 論叢 Vol.17 No.-

BMS 수리모형하에서 시스템의 수리효과 및 고장강도함수의 모수추정

윤원영,정석주,정일한,김종운,정상욱 한국경영과학회 2000 韓國經營科學會誌 Vol.25 No.4

Estimation problems of parameters of the failure process and the repair effect in repairable systems are considered. We propose estimation procedures in repairable systems without preventive maintenances. The fallure process is modeled by a proportional age reduction model (Brown. Mahoney, Sivazlian [5]) which is able to consider both aging and repair effects. Maximum likelihood method is used to estimate the repair effect and parameters of intensity function simultaneously. Simulations are performed to evaluate the accuracy of estimators. A numerical example is also presented.

유기용제 사용 소규모사업장의 체계적 건강관리 프로그램 개발에 관한 연구1) : 신경행동학적 검사법의 적용 가능성 Application of Neurobehavioral Core Test Battery(NCTB)

한상환,하미나,권호장,윤덕로,조수헌 大韓産業醫學會 1995 대한직업환경의학회지 Vol.7 No.2

It is known that there appear some nonspecific and delicate changes in neuropsychiatric aspect on the workers when they are exposed for a long period to low concentrated organic solvents in the work places. Therefore, it gives rise to the necessity of developing a program for the health supervisor stationed in the work place to supervise these neurobehavioral health affection. In addition to the questionnaire posed to the workers exposed to organic solvents, the study team conducted NCTB(Neurobehavioral Core Test Battery) respectively on an exposed group and a non-exposed group to organic solvents. The study team compared the results and decided whether or not to apply the results to the evaluation program of health affection. The study team divided 132 workers in 6 car repairing factories and 2 textile printing factories into exposed group and non-exposed group, pairing them off into 66 research objects according to their age, sex, and job. Neurobehavioral test was conducted on 6 items, except the POMS test, of NCTB developed by the World Health Organization(WHO). The study team conducted examinations of working environment on the exposed and non-exposed groups of each work place. The analysis of the collected materials for examinations were conducted with GC-MS. The concentration of the mixture in the air, relative to their respective threshold limit values(TLV) was calculated according to the formula of the ACGIH and the Korean threshold limits. The results indicated that for two of eight factories samples the recommended concentration limits for mixtures was exceeded. Of the six tests, the 'digit span forward', 'digit span backward' and 'digit symbol' produced conspicuous statistical differences between the two groups(p<0.1) as a result of compairing the test values by means of paired t-test. The results of respective analysis of the car repairing factories and textile printing factories revealed that the textile printing factories had greater differences between the exposed and the non-exposed than in the car repairing factories. It is presumably because the textile printing workers are continuously exposed to the organic solvents during working hours, whereas the car repairing workers are exposed only when they are doing painting works, The NCTB is assessed very useful in examining the neurobehavioral health affection under the exposure to organic solvents, and, therefore, the study team expects that the NCTB will play an important part in the course of developing a health program for the workers exposed to organic solvents.

鹿茸藥鍼液의 DNA chip을 利用한 遺傳子 發顯 分析

한상원,서정철,이윤호,최제용 大韓鍼灸學會 2003 대한침구의학회지 Vol.20 No.3

Objective : Bone homeostasis is maintained by balance of bone formation and resorption. Therefore, bone related diseases arose by disturbance of this balance between osteoblast and osteoclast activities. To develop a successful screening system the therapeutic components based on oriental medicine is essential to set up systematic approach for that purpose. The purpose of this study is to the know the gene expression using cDNA microarray assay. Methods : Cervi Pantotricuhum Cornu Herbal-acupuncture extract was prepared by boiling. human osteosarcoma cells(HOS) were treated with Cervi Pantotricuhum Cornu Herbal-acupuncture solution. Then mRNA was extracted and cDNA microarray assay was performed. Results : Human osteosarcoma cells(HOS) treated with Cervi Pantotricuhum Cornu Herbal-acupuncture solution(500㎍/㎖) showed that thioredoxin, TAFII31 and two novel genes were increased. However many genes decreased their expression by Cervi Pantotricuhum Cornu Herbal-acupuncture. Conclusions : This type of approach will give a good chance to explore the favorable effects of Cervi Pantotricuhum Cornu Herbal-acupuncture. Futher study is needed for investigating the effect of Cervi Pantotricuhum Cornu Herbal-acupuncture.

鹿茸藥鍼이 骨形成에 미치는 影響

한상원,최제용,이윤호 대한침구학회 2001 대한침구의학회지 Vol.18 No.5

Objective : Bone homeostasis is maintained by balance of bone formation and resorption. Therefore, bone related diseases arose by disturbance of this balance between osteoblast and osteoclast activities. To develop a successful screening system of the therapeutic components based on oriental medicine is essential to set out systematic approach for that purpose. Methods : This study was perforated Sprague-Dawley rat femur for bony defects(φ 5㎜) by the fissure bur. And experimetal group were treated with Cervi Pantotricuhum Cornu injection at both She`nshu~(BL23) & Da`zhu`(BL11)(0.2㎖). This was evaluated by radiography and histological analysis with in situ hybridization. Results : Cervi Pantotricuhum Cornu Herbal Acupuncture has weak effect on bony defect healing and this was evaluated by X-ray taking and histological analysis with in situ hybridization. Osteocalcin gene expression was not changed by Cervi Pantotricuhum Cornu Herbal Acupuncture in bony defects animal model. Conclusion : Taken together this study show that the Cervi Pantotricuhum Cornu herbal-acupuncture has a weak effect healing of bony defects, this type of approach might give a good chance to explore the favorable effects of Cervi Pantotricuhum Cornu herbal-acupuncture on bone tissue.

MALT 림프종을 수반한 쉐그렌 증후군

한원정,차상윤,김은경 대한구강악안면방사선학회 2000 Imaging Science in Dentistry Vol.30 No.2

Sj□gren's syndrome is a chronic inflammatory disease that predominantly affects salivary, lacrimal and other exocrine glands. We report a case of Sj□gren's syndrome combined with MALT (mucose associated lymphoid tissue) Iymphoma which occured in the parotid gland. A 57-year-old female with the complaint of painful swelling and iymph node enlargement was referred to our department. Sialograms of both parotid glands showed globular collections of contrast material uniformly distributed throughout the parotid gland. Salivary scintigraphy showed decreased uptake of the parotid gland. CT scan showed larger, slightly more dense parotid gland than normal and honeycomb glandular appearance. Also, It showed discrete, slightly more enhanced round mass in the left parotid gland. Histopathological finding showed replacement of salivary gland parenchyma with dense small lymphocytic infiltration having the feature of epimyoepithelial islands. Kappa light chain restriction of interglandular plasma cell could be seen. (Korean J Oral maxillofac Radiol 2000; 30: 144-148)

키토산에 대한 Itaconic acid의 graft 공중합과 그 특성

한상문,윤충수,김용범 서울산업대학교 산업대학원 1999 大學院論文集 Vol.6 No.-

Chitosan was prepared from chitin which was abstracted from wasted crab shell. Then itaconic acid was graft-copolymerized onto chitosan using ceric ammonium nitrate(CAN) as a reaction initiator. To investigate the optimal grafting conditions, the influences of several factors on the grafting were studied, i.e., the concentrations of CAN and itaconic acid, the reaction temperature and time. And to find out its flocculation ability, the flocculation test was carried out with a metal plating factory waste water. The state of the graft-copolymer was identified through IR spectra checking. The optimal grafting conditions and flocculation results were shown to be: concentration of ceric ammonium nitrate is ??, reaction temperature is 40℃ and reaction time is 4hrs with 0.25M of the monomer(itaconic acid). Through flocculation tests using chitosan, grafted chitosan(CsIa) and cation, CODcr, metal ions removal rates were measured. The order of superiority is CsIa>Cs>Cation.

결절성경화증 환자에서의 SPECT 뇌영상 : 예비적 연구 A preliminary report

한설희,이상수,정승연 충북대학교 의과대학 충북대학교 의학연구소 1991 忠北醫大學術誌 Vol.1 No.1

간질발작을 포함한 전형적인 삼징후가 동반된 결절성경화증 환자를 대상으로 뇌파검사, 뇌전산화단층촬영술 및 단일광자방출단층촬영술을 시행하였다. 뇌전산화단층촬영술에서는 상의하석회화병소와 조영제증강이 뚜렷하지 않은 피질에 연한 저음영 소견이 관찰되었으며 이어서 시행한 단일광자방출단층촬영술에서는 뇌전산화단층촬영술 소견보다 더 광범위한 부위에 관류결손이 관찰되었다. 단일광자방출단층촬영술은 결절성경화증 환자에서 간질발현 병소인 피질결절을 발견하는데 있어서 전산화단층촬영술 및 뇌파검사보다 더 유용한 방법이며 치료방침 결정이나 예후판정에 있어서도 큰 도움을 줄 것으로 기대된다. Two patients with a well-established diagnosis of tuberous sclerosis and epilepsies as their principal clinical symptom were examined by conventional surface electroencephalography(EEG), computed tomography, and single photon emission computed tomography(SPECT) using the 99mTc hexamethyl prophyleneamine oxime(99mTc-HMPAO). The interictal EEG showed various abnormalities of poor localizing value. Brain computed tomography surely demonstrated subependymal calcifications, although the cortical lesions were not so conspicuous. However, the SPECT images of each patient clearly demonstrated decreased cerebral perfusion in cortical areas. It may be assumed that such perfusion defect areas represent the epileptic cortical tubers or those of altered myelination, which are characteristics of the disease.