직교이방성 CFRP적층판의 초음파 탐사에 관한 연구

임광희,양인영,나승우 朝鮮大學校 機械技術硏究所 1999 機械技術硏究 Vol.2 No.2

This work ethibits how susceptive the shear ultrasonic waves are to a little misoriented plies according to the angle variation of shear ultrasoic waves 0˚, 45˚ and 90˚. Also, it is shown that shear waves, particularly the transmission mode with the transmitter and receiver perpendicular to each other, have high sensitivity for detecting anomalies in fiber orientation and ply layup sequence that may occur in the manufacturing of composite laminates. Experimental results are agreed with modeling solutions which were based on decomposition of shear wave polarization vector as it propagates through the composite laminates. This wave appeared considerably to be sensitive to CFRP composites to the thickness direction along in-plane fibers .

조도 감지기를 이용한 절전형 간판 자동 전원 제어기

라승탁(Ra, Seung-Tak),임송환(Lim, Song-Hwan),이승호(Lee, Seung-Ho) 한국전기전자학회 2016 전기전자학회논문지 Vol.20 No.2

본 논문에서는 조도 감지기를 이용하여 사용자가 설정한 조도량에 따라 점등되는 방식의 절전형 간판 자동 전원 제어기를 제안한다. 조도량 설정 방식은 사용자의 편리성을 감안하여 조도량 단위별 구간 분류 알고리즘을 통해 설정 과정이 누구나 쉽게 조작이 가능한 가변저항 방식을 제안한다. 자동 점등의 기준이 되는 조도량의 데이터는 조도 감지기가 측정한 조도량을 무선 통신을 통해 간판 자동 전원 제어기에 보내어 간판의 점등을 제어하게 된다. 본 논문에서 제안된 조도 감지기를 이용한 절전형 간판 자동 전원 제어기의 성능을 평가하기 위하여 공인 시험기관에서 외부의 빛이 모두 차단된 상태에서 시험한 결과, 각 구간별로 오차율이 ±3%이하로 측정되어 우수한 성능을 나타내었다. In this paper, we propose energy-efficient automatic power controller which can power on and off the signboard at the specified light intensity using the Illuminance Detector. By using segmented section Classification algorithm, light intensity setup system propose variable resistor method which makes users more easy to control. Automatic light on-off system set a standard by measured illuminance data. Measured light-intensity through the Illuminance Detector are communicated with the signboard power controller with wireless communication, and it controls lighting system. In this paper, we evaluated the Energy-Efficient Automatic Power Controller of The Signboard using illuminance detector. Experimental results in lightless environment shows that the error rate is less than 3% by Accredited Testing Laboratories.

Anti-inflammatory effects of PT-7 and Ilantide peptides on cultured keratinocytes and fibroblasts exposed to particulate matter 10

( Seung-yeon Lee ),( Bo-ra Lim ),( Chil-hwan Oh ),( Jeong-hee Kim ),( Kun Park ) 대한피부과학회 2020 대한피부과학회 학술발표대회집 Vol.72 No.1

Background: Recent research has indicated that Particulate matter (PM) induced inflammatory response in the skin. And it has been reported that Ilantide, interleukin-1 receptor antagonist, and palmitoyl tetrapeptide-7(PT-7) have anti-inflammatory effects. Objectives: We asked whether PM10 can stimulate the human skin keratinocytes and fibroblast to induction of inflammation and by what mechanism play the changes. Also, we asked whether Ilantide and PT-7 can suppress PM10-induced inflammation. Methods: Human skin keratinocytes, HaCaT, and human skin fibroblasts, HS68, were used. The MTT assay was used to measure the cell viability when PM10 was treated and when Ilantide or PT-7 were added to the PM10-treated cells. Western blot was used to measure the protein expression of inflammatory cytokines induced by PM10, Ilantide, and PT-7. Results: We found that PM10 decrease the cell viability of HaCaT and HS68, and induce various inflammatory cytokines from these cells. Also, we found that Ilantide and PT-7 induce the various expression rate of different inflammatory cytokines in these cells. Although Ilantide didn’t change cell viability, PT-7 increased cell viability in both HaCaT and HS68. Conclusion: These data demonstrate that PM10 decreases cell viability by inducing the increase of inflammatory cytokines in these cells and PT-7 can reduce inflammatory response induced by PM10. Therefore, it is expected that a method using this new peptide can be devised to reduce skin damage caused by PM10.

Cordycepin Induces Apoptosis through DR3 Pathway in Human Colon Cancer HT-29

Seung Yuan Lee,Sa Ra Park,Da Hye Kim,Tirishna debnath,Abul hasnat,Pervin mehnaz,Heung Mook Shin,Beong Ou Lim 한국식품영양과학회 2012 한국식품영양과학회 학술대회발표집 Vol.2012 No.10

The Safety and Efficacy of CKD-497 in Patients with Acute Upper Respiratory Tract Infection and Bronchitis Symptoms: A Multicenter, Double-blind, Double-dummy, Randomized Controlled Phase 2 Study

( Seung Won Ra ),( Sun Young Kim ),( Yun Young Lim ),( Shin Jung Park ),( Chin Kook Rhee ),( Deog Kyeom Kim ),( Yong Bum Park ),( Chang Youl Lee ),( Hyoung Kyu Yoon ),( Jeong-woong Park ),( Kwang Ha Y 대한결핵 및 호흡기학회 2020 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.128 No.-

Background Botanical medicines used as expectorants and antitussives have proven to be effective while also having excellent safety margins. We aimed at evaluating the efficacy and safety of a new botanical drug, CKD-497, in patients with acute upper respiratory tract infections and bronchitis. Methods In this phase 2 study, 225 patients were enrolled and randomly assigned to one of four treatment groups: placebo (n=55), Synatura® (n=49), CKD-497 200mg (n=68), or CKD-497 300mg (n=53). The study drugs were administered three times daily over the course of 7 days. Primary endpoint was the change in the bronchitis severity score (BSS) from baseline to day 7. Secondary endpoint was evaluated based on clinical response rates on days 4 and 7. A safety analysis was also performed. The Kruskal-Wallis test for intergroup differences and a Chi-square test were applied. Results Between baseline and day 7, the mean BSS scores decreased significantly in each group (P<0.001): 4.04±1.85, 4.31±1.47, 4.09±1.48, and 4.28±1.69. However, neither the CKD-497 nor Synatura® group showed any significant effect on the difference in BSS change (P=0.75). The rate of clinical response was higher in the CKD-497 300mg group as compared to the placebo only on day 4 (18% vs. 36%; P<0.05) and those having more severe bronchitis (phlegm score≥3) showed a significant reduction of total BSS in the Synatura® and CKD-497 groups (P=0.042). No significant adverse events were observed in either of the CKD-497 groups. Conclusion CKD-497 and even the positive control drug had no significant effect on BSS change in this phase 2 clinical trial. However, CKD- 497 300mg had a mild but significant clinical improvement in early bronchitis patients with more severe phlegm. Considering both efficacy and safety, a future study using 300mg of CKD-497 with a shorter-term endpoint is warranted in patients with more severe bronchitis symptoms.

한국인 폐확산능 정상예측식의 임상적 유용성과 정확성

나승원 ( Seung Won Ra ),박태선 ( Tai Sun Park ),홍윤기 ( Yoon Ki Hong ),홍상범 ( Sang Bum Hong ),심태선 ( Tae Sun Shim ),임채만 ( Chae Man Lim ),이상도 ( Sang Do Lee ),고윤석 ( Youn Suck Koh ),김우성 ( Woo Sung Kim ),김동순 ( Dong 대한결핵 및 호흡기학회 2008 Tuberculosis and Respiratory Diseases Vol.64 No.2

연구배경: 폐확산능을 해석하는 데 필요한 정상예측식으로는 한국인을 대상으로 하여 박 등이 개발한 식(박 식)이 있으나 아직 외국 정상예측식을 많이 사용하고 있다. 이에 국내에서 많이 사용하는 외국 정상예측식인 Burrows 식과 박 식의 임상적 유용성과 정확성을 비교하고자 하였다. 방법: 1. 임상적 유용성 연구; 2006년 7월부터 12월까지 6개월간 폐확산능검사를 시행한 환자 중 두 식을 각각 정상예측식으로 적용하였을 때 폐확산능 해석이 다른 276명(대상군 A)을 대상으로 하였다. 대상군 A에게 두 식을 각각 적용하였을 때 폐확산능 해석과 임상적 판단과의 일치도를 비교하여 임상적 유용성을 평가하였다. 2. 간질성폐질환 진단의 정확성 비교; 2001년부터 2006년까지 폐조직검사를 시행하여 확진된 간질성폐질환군과 서울아산병원에서 모집한 정상군을 대상으로 하여 정상예측식으로 두 식을 각각 적용하였을 때 폐확산능 해석의 정확도를 비교하였고, 두 식이 차이가 나는지 맥니머의 카이스퀘어 검정을 하였다. 결과: 1. 임상적 판단과의 일치도 비교; 276명을 임상정보를 토대로 폐확산능을 예측하여 분류한 결과 정상 54명, 감소 220명, 불분명이 2명이었다. 예측식으로 박 식과 Burrows 식을 적용하였을 때 임상적 판단과 일치하는 환자는 각각 78%와 22%이었다(p<0.001). 2. 간질성폐질환 진단의 정확성 비교; 박 식은 민감도 90.1%, 특이도 100%이었고 Burrows 식은 민감도 64.2%, 특이도 100%로 민감도가 통계학적으로 유의하게 박 식이 높았다(p<0.001). 결론: 우리나라 정상예측식인 박 식이 외국 정상예측식인 Burrows 식을 정상예측식으로 적용하는 것보다 임상적 유용성이나 간질성폐질환 진단의 민감도에서 더 우월하였다. 향후 폐확산능검사의 정상예측식으로 박 식을 사용해야 할 것으로 사료된다. Background: Park et al. developed the Korean reference equation for the measurement of diffusing capacity in 1985. However, the equation has not been widely used in Korea and foreign reference equations have been popularly used. We intended to compare the clinical usefulness and the accuracy of the the Korean reference equation (Park`s equation) with that of the foreign equation (Burrows` equation) that is commonly used in Korea. Methods: 1. Evaluation of clinical usefulness; Among 1,584 patients who underwent diffusing capacity (DLCO) at the Asan Medical Center from July to December 2006, group A subjects included 276 patients who had different interpretations of DLCO in trials employing Burrows` equation and Park`s equation. Clinical assessment was decided by consensus of two respiratory physicians. In order to evaluate the clinical usefulness of Burrows` equation and Park`s equation, agreement of clinical assessment and DLCO interpretation were measured. 2. Evaluation of accuracy; Group B subjects were 81 patients with interstitial lung disease (ILD) and 39 normal subjects. The 81 ILD patients were diagnosed following a surgical lung biopsy. The accuracy of diagnosing ILD as well as sensitivity and specificity were evaluated according to the use of the reference equations (Burrows` equation and Park`s equation) for DLCO. Results: Agreement between clinical assessment and interpretation of DLCO was 22% for the use of Burrows` equation and 78% for the use of Park`s equation. The sensitivity and specificity of the Burrows` equation for diagnosing ILD were 64.2% and 100%. The sensitivity and specificity of the Park`s equation for diagnosing ILD were 90.1% and 100%. The sensitivity of the Park`s equation for diagnosing ILD was significantly higher than that of Burrows` equation (p<0.001). Conclusion: The Korean reference equation (Park`s equation) was more clinically useful and had higher sensitivity for diagnosing ILD than the foreign reference equation (Burrows` equation). (Tuberc Respir Dis 2008;64:80-86)

A wavelet packet-based noise reduction algorithm of NTSC images using CVBS characteristics

Bo Ra Lim,Hyun Seung Lee,Rae-hong Park,Seungjoon Yang IEEE 2009 IEEE TRANSACTIONS ON CONSUMER ELECTRONICS - Vol.55 No.4

<P>This paper proposes a wavelet packet-based noise reduction algorithm for national television system committee (NTSC) images, in which the characteristics of a composite video burst signal (CVBS) are utilized. Most of conventional noise reduction algorithms apply spatial or spatio-temporal filtering only to the luminance signal, noting that the human eye is less sensitive to color than to luminance. Such noise reduction algorithms do not consider the realworld situation where a TV signal is transmitted over a noisy channel and decoded at a receiver. In this paper, it is assumed that an NTSVC signal is transmitted as a CVBS and corrupted with white Gaussian noise (WGN) by the channel. A CVBS has characteristics different from those of speech or image signals in a sense that encoded color information is modulated onto a high-frequency color subcarrier. The wavelet packet-based approach is suitable for noise reduction of the CVBS because decomposing a one-dimensional CVBS into eight subbands provides a chance to process each subband separately. In the proposed wavelet packet-based noise reduction algorithm, wavelet packet filtering is employed in subbands containing the color information whereas Wiener filtering is used in the other subbands. The separate treatment of each wavelet subband depending on the characteristics of CVBS leads to effective color and edge preserving noise reduction. The performance of the proposed method is validated by experiments with generated and corrupted CVBS images. Experimental results with various test images show that the proposed algorithm is effective in terms of the noise reduction efficiency and edge and color preservation.</P>

자기공명영상 검사실 업무종사자의 감염관리 실태에 관한 연구

라길수(Ra Kil-Soo),임청환(Lim Chung-Hwan),정성운(Jeung Seung-Woon) 한국콘텐츠학회 2015 한국콘텐츠학회 종합학술대회 논문집 Vol.2015 No.5

묵 형성 전분의 특성에 관한 연구

안승요,권미라,김성란,임경숙 한국농화학회 1992 Applied Biological Chemistry (Appl Biol Chem) Vol.35 No.2

Some physicochemical properties and molecular structure of cow pea, mung bean and acorn starches(mook-forming starches) and red bean, wheat and sweat potato starches(mook-unforming starches) were investigated. Amylose contents of cow pea, mung bean and acorn starch were higher than the others. Cow pea starch was similiar to mung bean starch in gelatinization characteristics by Brabender amylogram but cold viscosity of red bean starch and peak viscosity of sweet potato starch were especially high. Whereas viscosity of wheat starch was low in whole temperature range. Amylose molecules of larger molecular size(above 5×10^5 molecular weight) of three mook-forming starches were more than shoes of red bean and wheat starch. Chain distribution ratios(DP 35∼55 to DP 10∼20) of cow pea, mung bean and acorn amylopectin were higher than thoes of red bean, sweet potato and wheat amylopectin.

누리과정의 효율적 운영을 위한 교육계획안의 평가 내용 분석

임승렬(Lim, Seung-Ryoul),정미라(Joung, Mi-Ra),김연미(Kim, Yeon-Mi) 한국어린이미디어학회 2016 어린이미디어연구 Vol.15 No.2

본 연구의 목적은 유치원과 어린이집 교사들이 작성한 교육계획안의 자유선택활동, 대․소집단활동, 실외활동 평가 내용 분석을 통해 교사의 평가에 대한 인식과 어려움, 작성 현황을 파악해 보고, 이를 통해 평가가 유아의 학습과 성장에 기여할 수 있는 방안을 모색하는데 있다. 연구 참여자들이 작성한 평가 내용을 살펴본 결과, 첫째, ‘교육목표 달성 여부’관련 평가는 거의 이루어지지 않았다. 둘째, ‘교육내용’관련 평가는 자유선택활동영역에서 가장 많이 이루어졌으며, ‘추가된 교육내용’에 관한 평가는 이루어지지 않았다. 셋째, ‘교수․학습 방법의 적합 여부’와 관련된 평가는 유치원 교사들 경우 대․소집단활동에서만 이루어졌고, 어린이집 교사들은 각 활동 모두에서 이루어졌다. 넷째, ‘운영 환경 구성’관련 평가는 총 평가 내용의 10% 미만으로 이루어졌으며, ‘운영 환경 구성’평가의 필요성에 대한 인식 수준이 낮게 나타났다. 다섯째, ‘유아 평가’는 자유선택활동에서 가장 낮게 나타났다. 또한 유아평가(유아의 발달, 흥미, 태도) 중 유아의 발달에 관한 평가가 가장 적었다. 그 외 ‘교사 감정’관련 평가는 거의 나타나지 않았다. 누리과정의 목적을 달성하기 위해 교사는 평가의 목적을 구체적으로 이해하고, 평가 결과를 다음 차시 교육계획에 적용하는 순환 구조의 중요성을 인식할 수 있어야 할 것이다. 이를 위해 구체적 지침을 통한 평가가 실시 될 수 있도록 교사의 재교육 등 교사 지원이 절실히 요구된다. The purpose of this study is to explore the assessment content of free-choice activities, large/small group activities, and outdoor activities of lesson plans written by kindergarten and daycare center teachers, and to find out methods on how writing lesson plans can contribute to the learning and development of children. Upon analyzing assessment contents of lesson plans, first, kindergarten teachers did not assess the achievement of learning objectives, and daycare center teachers conducted such assessment, meaning no assessment had been conducted rarely. Second, regarding assessment of education content, kindergarten teachers showed higher assessment rate than daycare center teachers. Third, in regards to the assessment of appropriateness of teaching and learning methods, assessment was conducted in large/small group activities for kindergarten teachers, while assessment was conducted in activities for all categories while for daycare center teachers. Fourth, regarding the management of teaching-learning environment composition analysis, daycare center teachers conducted approximately four times more assessments than kindergarten teachers. Fifth, in terms of assessment of children, kindergarten teachers showed higher assessment rate than daycare center teachers, and both teachers conducted the least amount of assessment during free-choice activities. Also assessment on development of children was also conducted the least. Moreover, assessment was conducted on the emotional status of teachers. Teachers of early childhood education are required to understand the details of the purpose of assessment, and teacher support such as reeducation of teachers, are desperately needed, so that assessment through detailed instructions can be conducted.