연령증가에 따른 혈압요소들의 좌심실비대 및 관동맥질환과의 관련성

박재석,박창규,박미영,박재형,김용현,나진오,신성희,서순용,홍순준,박성미,임홍의,김응주,서홍석,오동주,노영무 대한순환기학회 2004 Korean Circulation Journal Vol.34 No.2

컬러모니터의 색상선호도 평가방법에 관한 연구

최재호 ( Jae Ho Choe ),박승옥 ( Seung Ok Park ),김흥석 ( Hong Suk Kim ) 한국감성과학회 1998 춘계학술대회 Vol.1998 No.-

This study investigated the evaluation method for the users`` color preference of CRT monitors. And also the users`` preference of the colors displayed on CRT monitor using the park``s color reproduction system was evaluated. Subjects conducted a series of psychophysical experiments to compare the colors displayed on a CRT monitor using the park``s system to the colors without the system, Three evaluation methods were investigated: comparing one colors of same hue with diverse luminance and saturation. the results showed that subjects preferred the colors reproduced using the park``s system, and thd evaluation methods significantly affected thd color preference.

노인의 Helicobacter pylori 재균율

박주상,홍원선,이영수,이은주,명승재,정훈용,양석균,김진호,민영일 대한노인병학회 2000 Annals of geriatric medicine and research Vol.4 No.3

Cortisone이 복막탐식세포의 탐식기능에 미치는 影響에 關한 電子顯微鏡的 硏究

朴永寬,洪錫宰 慶北大學校 醫科大學 1972 慶北醫大誌 Vol.13 No.2

It is well known that the phagocytic action of the cells of the reticuloendothelial system plays and important role in the immunological reaction and as a barrier against foreign bodies. It is also known that when the reticuloendothelial system is blockaded by cortisone, adherence of the foreign bodies to the cell membrane of phagocytes, and initial step of phagocytic mechanism, and absorption of foreign body into the cytoplasm of phagocytes are considerably disturbed. An investigation was undertaken to study the phagocytic activity of the omental milk spots by light and electron microscopy. Sixteen albino rats, maintained on a stock diet, weighing 200.0gm. average, were divided into 3 experimental groups. Group 1. Control group. No intraperitooneal injection of india ink given. a. Two rats, untreated. b. 2 rats: A dose of 25 ㎎ of cortisone acetate was given intramuscularly for 6 consecutive days. Group 2. 6 rats: A single dose of 6.0㎖ of 2% india ink in normal saline was given once a day, intraperitioneally, for 3 consecutive days. Group 3. 6 rats: A dose of 25 ㎎of cortisone acetate was given intramuscularly, once a day, for 6 consecutive days. Starting on the 4th day, a 6.0㎖ of 2% india ink in normal saline, once a day, wa administered intraperitoneally, for 3 days. Each of the experimental rats were sacrificed 24 hours after the last treatment of india ink preparation from the groups 2 and 3. The control group was sacrificed simillarly. Then the greater omentum was extirpated and inspected for india ink pigmentation of the milk spots, followed by both light and electron microscopic examinations. The results were as follows: 1. Light microscopic observations: In the experimental group of rats treated with 25 ㎎ doses of cortisone acetate with a resulant reticuloendothelial system blockade followed by an intraperitioneal india ink injection (group 3), the degree of carbon particle phagocytic activity of omental milk spots was greatly diminished over the group of rats treated with india ink only (group 2). 2. Electron microscopic observations: The number of phagosomes in the cytoplasms of the phagocytes of the milk spots of the greater omentum was increased substantially in the group of rate treated with india ink only (group 2). In this group, a large quantity of carbon particles were found to be contained in the phagosomes. Although there was an increased number of phagosomes bearing carbon particles in the group of rats treated with 25㎎ doses cortisone acetate followed by india ink injection (group 3), the number of phagosomes in this group was less than in the group of rats treated with india ink alone (group 2). A considerable quantity of carbon particles were also found outside the cytoplasms of phagocytes for group 3. It can be concluded, therefor: The phagocytic activity of omental milk spots was greatly decimated but not completely inbibited when the reticuloendothelial system was blockaded by large quantity of cortisone administration.

肥育牛의 濃厚飼料에 對한 香味素의 添加가 飼料의 攝取量, 增體量 및 飼料利用率에 미치는 效果

朴弘錫,許三男,崔亨松 全北大學校 附設 畜産開發硏究所 1987 畜産開發硏究報告 Vol.1 No.-

To investigate the effect of supplementing feed flavor in the beef rations containing urea on concentrate consumption, body weight gain and the efficiency of concentrate utilization two feeding experiments were conducted. Ten Holstein steers weighing 230-250㎏ were divided into groups and fed the control and the urea containing ration in the first trial for 50 days, then the feed flavor supplementing trial was followed for 136 days. Using urea at the level of 1.6% significantly(P<0.05) decreased both concentrate intake(5.37 vs 5.02㎏/day) and body weight gain(1.05 vs 0.93㎏/day). When the feed flaver (Aromastat for 61 days and followed by Beef-Feednectar for 75 days) was supplemented, it significantly(P<0.05) increased both the concentrate intake(7.90 vs 8.54㎏/day) and body weight gain(1.35 vs 1.47㎏/day). The efficiency of concentrate utilization was also improved but it was not statistically significant. Based on the results of the feeding trial, it is concluded that supplementing feed flavor in the ration containing urea improves feed consumption and growth of beef cattle.

美·日 貿易마찰을 통해본 미국의 政策代案

朴鴻錫 동아대학교 부설 사회과학연구소 1986 사회과학논집 Vol.4 No.-

The rise of protectionist sentiment in the United States has been closely related to the country's performance. Indeed, with $150 billion-plus trade deficit, it seems very natural for the U. S. government to put pressure on foreign countries to open their markets as well as to initiate a wide range of protectionist measures for its troublesome domestic industries. Unfortunately, however, the rising protectionism in the United states has become a threat to the international trade regime because of the country's traditional leadership role. In this respect, there is not much doubt that the U. S. economy should remain strong to maintain the commitment to the free trade regime. Why then, can the American industries not compete more effectively with foreign imports? In this paper, we have tried to answer this question by focusing on the United States and Japanese trade relations because we believe that the American trade problem has been basically a problem with the Japanese competitors. Thus, in short, we have focused on a few possible sources of the trade imbalance between the U. S. and Japan as follows : Dollar-yen misarrangement ; Japanese industrial policy ; lack of American industry's competitiveness, and the "closed" market in Japan. After a brief analysis of each one of these, we have dealt with the United States' pollicy alternatives. They include : industrial policy in the United States ; Protectionism ; Government-as-facilitator approach Follow-the-Japanese-Ways approach ; and international cooperation approach We have emphasized that these policy alternatives require an increased role of the government and changes in the conceptions of business-government and labor-management relations. But given the complexity and diversity of the American political system, the practicality of the alternatives seems not bright at the moment. As a theoretical consequence, we have tried to solve this paradowical problem by turning to the role of the President even though this solution seems rather superficial and flimsy. Yet, there are compelling needs for this. Of course, we can agree that the President is also greatly constrained. nevertheless, he, at least, has the power to persuade all those people around him. At least, we have greatly emphasized the desirability of Presidential role in the international economic relations.

약물치료에 가역적 회복을 보인 갈색세포종에 동반된 확장성 심근증 1례

홍숙경,최현,이승철,천경일,김영철,한재룡,김미숙,정경태,박순창 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.2

고정식 교정 환자에서 전동치솔 효과에 관한 연구

박창헌,황현식,이기헌,홍석진 대한치과교정학회 2004 대한치과교정학회지 Vol.34 No.4

고정식 교정장치를 부착한 경우 장치주위의 치태 축적 가능성이 증가되고 이로 인해 치은염, 법랑질 탈회 등의 부작용이 초래 될 수 있는 바 치태 제거를 위한 효과적인 치솔질이 필요하다. 본 연구는 교정환자에서 일반적으로 사용되고 있는 치솔에 비하여 전동치솔이 구강위생에 도움이 되는지 알아보기 위하여 시행되었다. 고정식 장치에 의한 교정치료 예정인 환자 34명을 본 연구의 대상으로 하여 고정식 교정장치 부착 전에 치태지수, 치은염지수, 치은출혈지수를 측정하였다. 장치 부착 4주 후에 각 지수를 측정한 다음, 연구대상을 치솔의 종류에 따라 전동치솔군과 수동치솔군으로 임의 구분하여 수동치솔 또는 전동치솔을 사용하도록 구강위생교육을 각각 시행하였다. 이때 전동치솔의 경우 본체는 Braun Oral-B D9511을 브러쉬 헤드는 Braun Oral-B Ortho OD 15-1을 사용하게 하였으며, 수동치솔의 경우는 Butler G.U.M 124를 사용하게 하였다. 구강위생교육 4주 및 8주 후에 각 지수를 측정한 다음 시간 경과에 따른 전동치솔군과 수동치솔군의 구강위생 상태를 비교 분석하여 다음과 같은 결과를 얻었다. 1. 고정식 교정장치 부착 4주 후 치태지수, 치은염지수, 치은출혈지수 모두 증가 양상을 나타내었다. 2. 구강위생교육 후 치태지수, 치은염지수, 치은출혈지수 모두 감소 양상을 나타내었다. 3. 치은염지수, 치은출혈지수의 경우 감소양상이 수동치솔과 전동치솔군 간의 유의한 차이를 보이지 않았다. 4. 치태지수의 경우 수동치솔에 비해 전동치솔군에서 감소효과가 유의하게 크게 나타났다. 이상의 연구 결과는 고정식 교정장치로 치료받는 환자에서 전동치솔이 구강위생에 도움이 됨을 시사하였다. Patients with fixed orthodontic appliances frequently have increased levels of plaque accumulation leading to the possibility of gingivitis or enamel decalcification. Although many methods may be helpful in reducing dental plaque formation, the optimal mechanical removal of plaque is the most important factor during orthodontic treatment. The purpose of this study was to evaluate the efficacy of an electric toothbrush (with a specially designed orthodontic brush head) compared to a manual toothbrush in controlling plaque and gingivitis for patients with fixed orthodontic appliances. Oral hygiene status was measured in thirty-four patients using a plaque index, a gingival index and a bleeding index, before and four weeks after the attachment of fixed orthodontic appliances. Patients were randomly divided into two groups: electric and manual toothbrush groups. Oral hygiene instruction was given according to the type of toothbrush used. The Braun Oral-B D9511 with Braun Oral-B Ortho OD 15-1 brush head was used as the electric toothbrush while the Butler G.U.M. 124 was given as the manual toothbrush. After four and eight weeks, oral hygiene status was measured again. Through a comparison between the electric and the manual toothbrush groups, the following results were obtained. 1. All oral hygiene indices showed an increasing tendency after four weeks of fixed orthodontic appliance. 2. All indices presented a decreasing tendency four and eight weeks after oral hygiene instruction. 3. In case of the gingival index and bleeding index, the decreasing tendency did not show a statistically significant difference between the electric and the manual toothbrush groups. 4. The decreasing tendency of plaque index presented a statistically significant difference between the two groups, showing that the electric toothbrush was more effective in terms of oral hygiene. These findings suggest that an electric toothbrush is useful to orthodontic patients with fixed appliances.

사람 위선암에서 cathepsin L의 발현증가

홍원선,홍석일,박인철,손영숙,정훈용,양석균,김해련,민영일 울산대학교 의과대학 1996 울산의대학술지 Vol.5 No.1

cathepsin L은 lysosomal cysteine 단백분해효소로서 기저막(basement membrane)과 세포외기질(extracellular matrix)을 파괴하여 암세포의 침윤과 전이에 중요한 역할을 하는 물질로 알려져 있다. 이러한 cathepsin L에 대한 mRNA 발현도를 5개의 사람 위선암(gastric adenocarcinoma) 세포주와 5명의 위선암 환자에서 채취한 조직에서 방사능으로 표지된 cathepsin L특이 cDNA를 사용한 Northern blot법으로 측정하였다. 위암의 전이병소에서 수립한 세포주인 SNU-5, SNU-16, MKN-45와 Kato Ⅲ에서는 cathepsin L mRNA가 발현되었으나 원발병소에서 수립한 AGS 세포주에서는 mRNA의 발현이 관찰되지 않았다. 5명의 위암 환자에서는 원발병소, 전이가 확인된 임파절 및 암 근처 정상 위점막에서 각각 조직을 채취하여 cathepsin L mRNA의 발현을 측정하였다. 원발병소와 전이병소에서는 모두 cathepsin L mRNA가 발현되었으나 정상 위점막조직에서는 전예에서 mRNA 발현이 관찰되지 않았다. 한편 mRNA의 발현도는 1예에서는 전이병소가 원발병소에 비해 높았으나, 2예에서는 전이병소에서 발현도가 낮았으며, 나머지 2예에서는 원발병소와 전이병소 사이에 차이가 없어, 원발병소와 전이병소 사이에 mRNA의 발현도의 일관성 있는 경향은 관찰되지 않았다. 이상의 결과는 cathepsin L은 위암의 발생과 진행에 있어 암세포의 침윤과 전이를 촉진하는 것 이외에 또 다른 역할을 할 가능성을 시사하고 있다고 사료된다. Cathepsin L, a lysosomal cysteine protease, is known to play an important role in cancer invasion and metastasis by degrading the components of basement membrane and extracellular matrix. The mRNA expression of cathepsin L was determined by Northern blot analysis using a radiolabeled cDNA specific for cathepsin L in five human gastric adenocarcinoma cell lines and five surgical specimens of primary gastric adenocarcinomas, their metastatic lymph nodes and matched adjacent normal mucosae. The mRNA of cathepsin L was expressed in all of the four cell lines established from the metastatic sites, SNU-5, SNU-16, MKN-45 and Kato Ⅲ, while not detected in one cell line established from the primary site, AGS. The mRNA was expressed in all of the five primary and five metastatic cancer specimens tested, while it was not detected in all matched normal mucosae. The intensities of the mRNA expressions, however, did not show the consistent pattern between primary sites and metastatic lymph nodes. These results suggest that cathepsin L may have the other function in addition to facilitation of the invasion and metastasis during the development and progression of stomach cancer.

칼라영상 입력장치의 분광감도 측정 및 분석

朴勝玉,朴正萬,金洪錫 대진대학교 1994 大眞論叢 Vol.2 No.-

The tristimulus values of an object color are dependent on both the spectral power distribution of the illuminant and the surface reflectance of the object. Futhermore the physical factors that are relevant to color image processing are camera sensor spectral responses and monitor phosphor power distributions In this paper, we constructed the optical system for the measurement of camera spectral responses As a result, we obtained spectral sensitivity functions of a camera corresponding to rλ￣, gλ￣, bλ￣ color matching functions.