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      • Development of a Mobile Application, "Wild Flowers of Bukhansan National Park (version 1.0)", for Identification of Plants in Bukhansan National Park

        Kim, Sang-Tae,Lee, Seung-Yeon,Kim, Seung-Chul,Byun, Hye-Won,Lee, Sang-Tae,Kim, Mu-Yeal,Hong, Seok-Pyo,Chung, Young-Jae,Park, Ki-Ryong,Lee, Chung-Hee,Lee, Joong-Ku,Heo, Kyeong-In,Lee, Ji-Ye,Lee, Eun-Je National Science Museum of Korea 2011 Journal of Korean nature Vol.4 No.3

        We developed the educational purpose mobile application, named "Wild Flowers of Bukhansan National Park (version 1.0)", aiming for easy identification of wild flowers for students and visitors in the park. When visitors find a flower or part of plant in the park, visitors can search for its name utilizing the pictures and characters provided in their own smartphone mobile devices or tablet PCs. The application provides pictures of wild flowers in the park and character-based searching system based on 12 diagnostic features (e.g., growth form, leaf arrangement, flower symmetry, petal color, petal number, sepal number, etc). We adopted the complete floristic survey of Chung and Lee (1962) and added species that we confirmed their distribution in the park during the development of this application. In summary, number of vascular plants in this park was estimated to be 428 taxa including 100 families, 280 genera, 327 species, 1 subspecies, 50 varieties, and 5 formas. We provided a total of 588 pictures representing 358 taxa and each taxon includes multiple pictures in many cases. Included identification quizzes can be an efficient educational tool as well as fun activity for students and visitors who are learning plant species in Korea. Our next step will include GPS function in the application for indicating visitor's location and for providing previously reported sites of the species that we interested in the map of the park. The future application which includes GPS function will be a valuable tool for the monitoring of rare plants, plant researches related to the climate changes, etc. We currently provide Korean iPhone version only, and English version and both of android versions will be serviced soon.

      • Effect of Ionizing Radiation on Rat Tissue: Proteomic and Biochemical Analysis

        Park*, Eui‐,Chul,Yoon, Jong‐,Bok,Seong*, Jin‐,Sil,Choi, Kyoung‐,Soo,Kong, Eung‐,Sik,Kim, Yun‐,Jeong,Park, Young‐,Mee,Park, Eun,Mi Taylor Francis 2006 Preparative biochemistry & biotechnology Vol.36 No.1

        <P>Reactive oxygen species (ROS), generated by ionizing radiation, has been implicated in its effect on living tissues. We confirmed the changes in the oxidative stress markers upon irradiation. We characterized the changes in the proteome profile in rat liver after administering irradiation, and the affected proteins were identified by MALDI-TOF-MS and ESI-MS/MS. The identified proteins represent diverse sets of proteins participating in the cellular metabolism. Our results demonstrated that proteomics analysis is a useful method for characterization of a global proteome change caused by ionizing radiation to unravel the molecular mechanisms involved in the cellular responses to ionizing radiation.</P>

      • SCIESCOPUSKCI등재

        The rs196952262 Polymorphism of the AGPAT5 Gene is Associated with Meat Quality in Berkshire Pigs

        Woo Bum Park,Sang Mi An,Go Eun Yu,Seulgi Kwon,Jung Hye Hwang,Da Hye Park,Deok Gyeong Kang,Tae Wan Kim. Hwa Chun Park1. Jeongim Ha*.,Chul Wook Kim* 한국축산식품학회 2017 한국축산식품학회지 Vol.37 No.6

        High-quality meat is of great economic importance to the pig industry. The 1-acylglycerol-3- phosphate-O-acyltransferase 5 (AGPAT5) enzyme converts lysophosphatidic acid to phosphatidic acid in the mitochondrial membrane. In this study, we found that the porcine AGPAT5 gene was highly expressed in muscle tissue, influencing meat characteristics, and we also identified a non-synonymous single-nucleotide polymorphism (nsSNP) (rs196952262, c.673 A>G) in the gene, associated with a change of isoleucine 225 to valine. The presence of this nsSNP was significantly associated with meat color (lightness), lower cooking loss, and lower carcass temperatures 1, 4, and 12 h after slaughter (items T1, T4, and T12 on the recognized quality scale, respectively), and tended to increase backfat thickness and the waterholding capacity. These results suggest that nsSNP (c.673A>G) of the AGPAT5 gene is a potential genetic marker of high meat quality in pigs.

      • SCIESCOPUSKCI등재
      • 요중 Protein 및 N-Acetyl-β-Glucosaminidase의 생물학적 변동에 관한 연구

        朴園,李恩一,車喆煥,張聖薰 고려대학교 의과대학 1992 고려대 의대 잡지 Vol.29 No.1

        The purpose of this study was to evaluate the biological variations of N-acetyl-β-glucosaminidase activity, beta-2 microglobulin, alpha-1 microglobulin, total protein, and microalbumin in spot urine specimens, all of which have been used as a screening test for the evaluation of renal dysfunction. The study was conducted from June to August of 1991, with analysis-evaluation of the 24-hour urine specimens with that of 3 spot-urine specimens and first morning specimen. A total of 14 healthy college student volunteers (non-exposed group) and 42 workers exposed to carbon disulfide (exposed group)were selected as the study subjects. The results were as follows ; 1. The mean values of N-acetyl-β-glucosaminidase activity and alpha-1 microglobulin in 24 hour urine specimens in the exposed group were higher than those in the non-exposed group. 2. Coefficient of variation among spot urine specimens of N-acetyl-β-glucosaminidase in exposed group was the lowest among the results of 5 different types of urine tests. 3. The correlation coefficients between the values in 24 hour urine specimens and those in spot urine specimens were above 0.9 for total protein. microalbumin, and alpha-1 microglobulin. The correlation coefficients between the NAG activities in 24 hour urine specimens and those in spot urine specimens were relatively high. 4. Of the total 25 workers who showed a higher N-acetyl-β-glucosaminidase activity than the reference data for the 24 hour urine specimens, the number of workers excessive reference data for the spot urine specimens was 23(92%), and 22(88.9%) for the first morning urine specimens.

      • KCI등재
      • SCOPUSKCI등재

        수부손상에 대한 임상적 고찰

        박명철,최은정,차진한 大韓成形外科學會 1993 Archives of Plastic Surgery Vol.20 No.1

        The hand has much more delicate functions to be performed and its structural characters shoud be fully understood to mannage them properly. In care of hand injuries, is is essential for prevention of deformities and residual sequelas after injury, exact preoperative diagnosis, proper treatment, and intensive postoperatvie care. A statistical analysis was carried out on 464 patients of hand injuries, who were treated at the Department of Plastic, and Reconstructive Surgery, Konkuk University hospital, from October, 1988 to December, 1991. The followings are the results of our analysis, 1. The peak incidence rate was in the age group of 20-29 yerars(40.9%) and most of all were male in 87.4% 2. The glass injury was the most common cause of injuries in 30.4%. 3. Most of the patients were able to get the chance of early medical card by arriveing hospital within six hours in 87.7%. 4. There were no significant difference rate of all seasons. 5. The most frequency of admission duration was 1 week(53.0%) and OPD treatment usually lost for 1-2months(61.2%) 6. Monodigit injury(47.4%) was most frequenly involved, of mondigit injury was index finger(31.3%) 7. The type of injury was mainly crushing(40.3%), involving multiple structures. 8. 26.5% of hand injuries were treated with debridement and multiple combined operation. 9. Various complication of hand injuries were observed in 5.8% and the most commin complication was infection in 10 cases(37.1%). 10. Results of recovery was more excellent in a single injury than combined injury.

      • 분만시 지속적 또는 간헐적 투여에 의한 경막외 제통의 비교

        박욱,이은찬,배상철,강규식,곽수달 순천향의학연구소 1997 Journal of Soonchunhyang Medical Science Vol.3 No.2

        Background : Continuous epidural infusion of the mixed solution of local anesthetic (bupivacaine) and lipid-soluble opioid (fentanyl) has known as a more useful method than intermittent epidural injection for relief of pain during labor. The purpose of this study was to compare a clinical usefulness between continuous infusion and intermittent injection with epidural analgesia during labor. Methods: One hundred healthy parturients were divided into two groups as follows: Continuous epidural group (C-group); 50 parturients received epidural analgesia continuously with 0.167% bupivacaine and 0.000167% fentanyl in the speed of 10 ml h-1 at cervical dilatation (3-5 cm) and then injected 0.25% bupivacaine 5 ml additionally at complaints of severe labor pain. Intermittent epidural group (I-group); 50 parturients received inermittently 0.167% bupivacaine and 0.00083% fentanyl in the initial dose of 12 ml at cervical dilatation (3-5 cm) and then additionally used the same dose at severe labor pain. Result: There were no statistically significant differences in the clinical states of maternoneonate, pain free score, degree of motor block, mode of delivery, cause of Cesarean section, neonatal Apgar score and incidence of side effects between groups(Table 1.2.3.7.8). The total dose of bupivacaine and fentanyl, the duration of lst and 2nd delivery stages and the frequency of top up injection for incomplete relief of pain during labor appeared significant differences in statistics between groups (Table 4.5.6). Conclusion: It was similar to the effectiveness of maternal epidural analgesia during labor between groups by means of continuous or intermittent injection.

      • KCI등재후보

        이황화탄소 폭로 남성 근로자의 진동감각 역치에 관한 연구

        박승희,이은일,천병철,염용태,최재욱 大韓産業醫學會 1996 대한직업환경의학회지 Vol.8 No.1

        This study was conducted on 367 male workers to evaluate the change of vibration perception threshold(VPT) according to exposure degree to carbon disulfide. VPT was measured on both metacarpal bones of index and little fingers and on fibular malleoli by Vibrometer(Rion, on 125Hz). The exposure degree was classified by the name of department. Workers in department 2 had been exposed to carbon disulfide, those in department 3 had been exposed to undetectable concentration of carbon disulfide. The results were as follows: 1. The mean values of VDT of metacarpal(MC) bones showed dose-response pattern, i.e., the mean values of VPT at department 1 were highest, and those of VPT at department 3 were lowest with similar work duration or age. But the mean values of VPT of fibular malleoli(FM) showed dose-response patter only in workers having above 5 years of work duration or whose age were above 30. 2. The mean values of VPT of MC bone of workers increased by age. 3. There were statistically significant difference in mean values of VPT of MC bone only in workers having 5-10 year work duration. And there were statistically significant difference of mean values of VPT of left 2nd and 5th MC bone in workers whose age was 30's, of right 2nd MC bone in those whose age was 40's, and of left 2nd MC bone in those whose age was 50's. 4. The variables affecting VPT significantly were department and age(or age group) both in multiple regression and general linear model. The department showed to have more effect to VPT than age in multiple regression, but age group showed to have more effect to VPT than department in general linear model. 5. The variables were transformed to indicator variable to do logistic regression analysis. department 1, 2, 3 were classified into high exposure(spinning department) and low duration was classified into long(above 10 years) and short. The exposure and age were significant variables by logistic regression analysis. Odds rations of department and VPT on metacarpal bones or malleoli were 2.7-3.2 and VPT those were 2.6 or 2.7. Odds ratio of age and abnormality of VPT on any point was 3.3(1.59-6.8), and that of department and VPT was 2.8(1.5-5.5). We concluded that exposure of carbon disulfied was significantly associated with reduction of VPT regardless of age; and that the test of VPT would be useful tool for screening and early detection in neuropathy by carbon disulfide or other neurotoxic chemicals, even though it is simple and cheap.

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