서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1994)

김재홍,안진균,정성재,김영태,김중환,김시영,이석종,이홍렬,서호석,김경훈,권혁진,정우권,고우석,이용석,안필수,오준규,오용섭 대한화학요법학회 1996 대한화학요법학회지 Vol.14 No.1

Background : In recent years gonorrhoea has been panendemic and remains one of the most common Sexually Transmitted Diseases in the world, especially in developing countries. Objective & Method : For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria Gonorrhoeae(PPNG), Ive have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results : In 1994, 168 strains of N. gonorrhoeae were isolated, among which 109 (64,9% ) were PPNG. Conclustion : Our results suggests that the prevalence of PPNG in Seoul is still increasing.

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

양파즙을 이용한 ethanol 발효조건에 관한 연구

오영준 東新大學校 1997 論文集 Vol.9 No.-

From onion, about 10strains were isolated and tested for their ability of alchol fermentation. Among them, one strain YJ-1, showing the highest alchol fermentation ability was selected for futher investigations. It was identified as Soccharomyces cerevisiae based on their morophological, cultural properties. The optimum condition for the alchol fermentation in a onion juice by Saccharomyces sp. YJ-1 was performed. Heat treatment of onion juice at 100℃ for 3min. was most effective for alchol fermentation production. K_2S_2O_5 at the concentration of 100ppm was similarily effective in onion juice cotaining 25% sugar for alchol production.

태권도 지도자들의 지도자 연수 프로그램 인식도에 관한 연구

오대영,박준석,진중의 龍仁大學校 武道硏究所 1997 武道硏究所誌 Vol.8 No.2

In this assertation I tried to investigate the disposition of what the Taekwondo masters think of the training programes for the Taekwondo masters and then tried also to study the direction of its advancement. The conclusions I obtained through the assertations are like the followings. First, for the most important reasons, the Taekwondo masters attend such training programes because it is necessary(40.9%), second for the development of himself(30.3%), third to help the educations on the next generation(26.8%). Second, they are satisfied with the facilities of training institute(56.1%) 26.8% feel inconvinient. Third, those who lecture in the training programes are sincere and feel that the training programes are helpful in the knowledge and skills. Forth, the exercise programes are the most helpful ones among all the training programes and the masters prefer the programes that are useful in actual situations. Thus, we can conclude that the current training programes are necessary for the trained, and it is required to found more facilities and various programes based on the enough investment.

별'에 대한 초등학교 교사와 학생들의 幼年的 槪念과 核心 信念 비교

오준형,채동현 경북대학교 사범대학 부속 중등교육연구소 2004 중등교육연구 Vol.52 No.1

This article presents the results which investigated elementary school students' and teachers' conceptions about the stars. Samples consisted of one hundred forty eight 5th-grade students, one hundred seventy four 6th-grade students, and thirty eight primary science teachers. Research method was paper-pencil test. Their responses to these questions revealed considerable apparent naive conceptions. and the study results proved that the items showing a high response rate of teachers' childhood concept also resulted in a high response rate of students' naive concept. A great of this apparent inconsistency could be explained by assuming that the students used, a naive core belief of the stars other than a target scientific concept of the stars. And, elementary school students and teachers often held a different naive core beliefs based on their other experiences rather than scientific theories. this paper was also discussed the core beliefs that elementary school students and teachers held to overcome these naive conceptions.

水分蒸發이 시멘트 모르타르의 휨强度에 미치는 影響

吳武泳,金駿熙 충북대학교 농업과학기술연구소 1989 農業科學硏究 Vol.7 No.2

This study was carried out in order to research executed strength loss of concrete in the terms of dryness weather, water evaporation action was affect the bending strength of cement mortar after casting. The mix property of cement-fine aggreagte was 1 : 1, 1 : 3, 1 : 5. And the terms of curing was compared standard curing with direct dryness curing after casting. And 3days,7days,14days strength of mortar was examined. The results obtained fl·on this study are summarized as follows. ① Bending strength of standard curing mortar and direct dryness curing mortar were all together decreased by increasing the mix property of cement-fine aggregate. ② When the period of curing was increasing, bending strength of standard curing mortar was inc-reased without relation at mix property of cement-fine aggregate. But direct dryness curing mo-rtar was decreased. ③ Strength difference between standard curing mortar and direct dryness curing mortar was exte-nsioned by increasing the period of curing. ④ Strength difference between standard curing mortar and direct dryness curing motar was exten-sioned by increasing the mixing volume of cement. ⑤ We must take some measure to cope with water evaporation control by increasing the cement volume in the process of curing the terms of dryness weather.

濕式法에 依한 輝安鑛으로부터 三酸化 안티모니의 製造에 關하여

오재현,김준수,고인용,정원용 연세대학교 산업기술연구소 1979 논문집 Vol.11 No.1

An investigation on the production of high purity Sb₂O₃was carried out by means of the acid leaching process from the roasted ore of stibnite. The approach of these studies has been to investigate purity, particle size, recovery and crystal structure of Sb₂O₃obtained through the subsequent treatments of leaching, hydrolysis and neutralization under various conditions. The results obtained in these experiments are summarized as follows; 1) It was possible to use dilute hydrochloric acid to extract Sb₂O₃from the roasted stibnite. Because of the prior roasting treatment, the contamination of impurities could also be reduced in the final products. 2) The rate of extraction of Sb₂O₃from the roasted stibnite was increased concentration of hydro-chloric acid as increased amount of addition of the acid. 3) The yield of Sb₂O₃obtained by hydrolysis of SbCl₃was increased with increasing temperature of hydrolysis. 4) The crystal structure of Sb₂O₃obtained by hydrolysis of SbCl₃at 20℃(room temperature) was confirmed as a orthorhombic crystal structure which is the same as that of valentinite. The recovery of Sb₂O₃from the roasted ore appeared to be nearly 100% under optimum conditions.

동양배(Pyrus serotina)로부터 분리된 알코올발효 효모의 특성

오영준,김재창 東新大學校 工業技術硏究所 2000 工業技術硏究 Vol.6 No.-

From Pyrus serotina, 20 yeast strains were isolated, and tested their ability of alcohol fermentation. Among them, two strains YJ 7 and YJ 8 showing the highest alchol fermentibility were selected for further investigation. They were identified as Saccharomyces sp. based on morphological and cultural properties. Their optimum condition for alcohol fermentation in the medium containing 1% yeast extract, 20% glucose and 1% peptone was pH 5.0, 30℃ and 100rpm of shaking speed. The alcohol yields of Saccharomyces sp. YJ 7 and Saccharomyces sp. YJ 7 in a pear juice of Pyrus serotina were 96.54% and 95.36%, respectively. They were much higher in a pear juice as compared to those of Saccharomyce cerevisiae DF 639.

Morgagni 탈장 : 1례 보고

오연희,이창욱,김승현,이성우,정병욱,이준희,박동일,권영무,신현종 동국대학교 경주대학 1996 東國論集 Vol.15 No.-

Morgagni 탈장은 횡격막의 전내측 부위의 발달이상으로 열공을 통하여 장관이나 대망과 같은 복강내 구조물이 흉곽내로 빠져나가는 드문 질환으로 알려져 있다. 저자들은 호흡곤란을 주소로 내원하여 방사선학적 검사와 수술로 확진된 1례를 보고한다. Morgagni hernia is improperly located abdominal viscera into the thoracic cavity through the foramen of Morgagni which is a congenital defect at the anterornedial portion of diaphragm. We report a case of Morgagni hernia diagnosed by radiologic examination and operation.

만화 과제를 이용한 정신분열병 환자의 사회인지 능력의 측정

오정은,나명현,하태현,신용욱,노규식,홍순범,이경진,신민섭,이영호,권준수 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.3

Objectives : This study is to investigate the hypothesis that schizophrenic patients have difficulty in inferring mental state of others. Methods : Twenty schizophrenic patients and twenty normal subjects were administered to the Cartoon Task required inferring the character's intention in a given context. Results : The schizophrenic patients showed a statistically significant impairment in the Cartoon Task. Both groups chose the card depicting a frequent everyday action significantly more rather than the similar card to the last picture in each story for wrong answers. Conclusion : These preliminary results suggest that schizophrenia is associated with a specific deficit of the cognitive ability referred to as social cognition, and this deficit can be detected not only in the acute phase as found in previous research studies, but also in remission. Also when subjects fail to appreciate what is going on in the minds of other people, they seem to rely on a socially familiar experience.