비안와대뇌형 모균증 치험 3례

문영일,김종남,홍순관,이지애,정옥경,김문정 梨花女子大學校 醫科大學 醫科學硏究所 1997 EMJ (Ewha medical journal) Vol.20 No.3

Rhinocerebral mucormycosis is a well-described fulminant fungal infection that typically presents in a rapidly fulminant manner. This condition is more likely to occur among patient with diabetes mellitus, malignant tumors, who have long-term steroid treatment, or who suffer from some debilitating diseases. We report 3 cases of rhinoorbitocerebral mucormycosis, all suffered from diabetes mellitus. In all 3 cases, endoscopic sinus surgery was done and the antifungal agent(amphotericin B) was administered intravenously, and two patients died. One survivor who had focal extension of paranasal sinus and orbit, required one surgical intervention without orbital exenteration and he is alive without recurrence disease. The severity of the disease is probably dependent upon the gost resistance to the invasion of phycomycetes. Early diagnosis and immediate, effective treatment are the key for cure of the disease.

서식문서의 구조분석 및 자동 HTML 변환

문경애,백순흠 공주영상정보대학 1999 논문집 Vol.6 No.-

본 논문에서는 내용이 채워진 임의의 서식문서의 구조분석 및 표현에 관한 방법을 설명하였다. 제안한 방법은 위상(topology)을 유지하는 범위에서는 변형이 있어도 동일한 서식으로 간주하는 논리적 형식의 구조분석 방법으로 크기와 위치의 변형에 민감하지 않으므로 최소한의 등록으로 서식의 분류가 가능하였다. 또한 기존의 방법들에서 처리가 곤란했던 서식의 선이 깨어진 경우, 점선의 서식의 경우, 항목 내에 필기한 문자와 서식의 선이 접촉된 경우, 서식이 기울어진 경우 등에서도 좋은 결과를 보여 다양한 실험 데이터에 대해 약 97% 이상의 항목 추출율을 보였다. 그러나 서식 선과 항목 내에 필기한 문자가 붙은 경우 추출된 각 항목, 즉 내용필드의 문자들이 파손되어 문자 인식율이 저하되었다. 앞으로 전체적인 F-DAS시스템의 성능 향상을 위해서는 항목내의 인쇄 및 필기 문자들의 분리 방법에 관한 연구 및 서식과 붙어서 생긴 파손된 문자의 복원에 관한 연구가 이루어져야 할 것이다.

혈장 중 Cefprozil의 이성체인 cis-Cefprozil과 trans-Cefprozil의 동시분석법

조애리,문희경,이성창 德成女子大學校 藥學硏究所 2004 藥學論文誌 Vol.15 No.1

Cefprozil is a broad-spectrum oral beta-lactam cephalosporin consisting of cis-- and trans-isomers in and approximately 90:10 ratio. To establish an assay condition for a Bioequvalence study of cefprozil, a column liquid chromatographic (HPLC) method using UV detection for the determination of the cis- and trans-isomers of cefprozil in blood has been developed. The HPLC apparatus used in this study was Waters 2695 Separation Module (Alliance) system. Samples were analyzed with dual absorbance detector (280㎚). C8 (150×4.6㎜, Luna 5㎛, Phenomenex) column with column inlet filter (3㎜×O.5㎛), provided a good resolution, The mobile phase was composed of acetonitrile : glacial acetic acid : water: (5:2:93 as v/v/v, pH 2.7). The flow rate was 1.0㎖/min. Typical retention times with Luna column were 10.8, 14.8 and 20.5min for cis-cefprozil, trans-cefprozil and cepharolidine (internal standard), respectively. For the data manipulation, Waters Millennium program was employed. Calibration curves for the determination of cis-cefprozil and trans isomers of cefprozil in plasma showed a good linearity at a concentration range from 0.05 to 15㎍/㎖ (r²=0.999) and 0.01-1.5㎍/㎖ (r²=0.998). The lower detection limits for cis- and trans-cefprozil were 0.05 and 0.01㎍/㎖, respectively.

NIHSS 활용을 통한 뇌졸중 환자 간호의 질향상 전략

박경현,송경애,공혜성,나화주,유수경,박소영,김상희,최혜림,배희준,한문구,양미화 한국의료QA학회 2009 한국의료질향상학회지 Vol.15 No.2

문제: 뇌졸중 환자를 돌보는 간호현장에서는 급성기 뇌졸중 환자의 증상악화에 대한 조기사정과 적절한 대처가 매우 중요한 문제이다. 그러나 임상현장에서는 이를 객관화하고 수치화하여 모든 의료진이 의사소통할 수 있는 유용한 도구를 사용하고 있지는 못하는 실정이다. 이러한 문제를 해결하기위해 NIHSS(National Institute of Health Stroke Scale)를 신경과 진료의사를 중심으로활용하고 있지만 아직 간호현장에서는보편적으로사용하지 않고있다. 이에 뇌졸중환자간호에 NIHSS를 활용하여 뇌졸중 증상악화의 조기사정과 빠른 대처로 궁극적으로는 뇌졸중환자 간호의 질을보다 향상시키기 위하여 본활동이 시도되었다. 목적: 첫째, 간호사의 NIHSS 측정 신뢰도의 현수준을 점검하고 이를향상시키기 위한 프로그램을 개발·적용한다. 둘째, 간호사가급성기 뇌졸중환자에게 NIHSS 측정을 통하여 뇌졸중악화를 얼마나 예측할 수 있는지 분석하고 이를 향상시킬수있는 방법을 모색한다. 셋째, 궁극적으로 급성기 뇌졸중 환자의 증상악화의 조기 발견과치료를위한의료진의 올바른 대처지침을 마련하여 이를 적용한다. 의료기관: 경기도에 소재한 대학병원의 뇌졸중 집중치료실 질 향상 활동: 첫째, 간호사의 NIHSS 측정 신뢰도 향상을 위해 「NIHSS 간호사 교육 프로그램」을 마련하였다.

간호정보 검색방법 탐구 : Internet 및 CD-ROM 등을 기본으로

서문자,한경자,최명애,김정은,홍경자,박성애,이명선 서울대학교 간호대학 간호과학연구소 1999 간호학 논문집 Vol.11 No.2

The purpose of this study was to explore how to access nuring information using computer and other softwares. It described the ways to reach and get the database on abstracts of masters' and doctoral dissertations in nursing and medicine in Korea. It also provided the ways to get nursing related database around the world, such as Medline, using internet search tools. Internet search tools included databases and their themes and unique characteristics. In addition, the study illustrated the ways to use netscape navigator using LAN or modem and to use CINAHL-CD-Rom title which is commonly utilized in nursing. The results of this study might help nurses and nursing scholars efficiently access the needed information and database which can be utilized in education and research areas.

의류상품의 특성과 문제점 개선안에 관한 연구

방경혜,송민재,이영해,조현애,최문희 연세대학교 생활과학대학 1985 婦學 Vol.18 No.-

Nowdays, proper merchandising system of clothing is needed not only for functional clothes but also for fashionable ones. Since nineteen eighties, ready­to­wear garments have been popular for Korean women. But it is hard to tell whether or not the system of the ready­to­wear industry is concrete because of the short history. The purpose of this study was to investigate the process of the merchandising system of the ready­to­wear garments and to recognize the problem which the system of the garments had have. Furthermore, it aimed to find out the idea or improving the problem for better ready­to­wear garments. This research was done through information obtained from several libraries. And, the period of this was from May of August, 1984. The results of this study were: 1. There was an indivisible relationship between merchandising system and fashion, and the importance of the merchandising­planning was raised. 2. The manufacturers should research and analyze consumers since they are aiming at them in nature. 3. The manufacturers should aim at the invention of the creative designs and the introduction of advanced techniques in producing textiles and their accessaries. 4. There should be some institutes to teach fashion and other areas related to ready­to­wear garments. 5. It was necessary to inform consumers to be able to select proper garments in the market.

Phytochrome이 보리잎 Protoplast의 팽윤에 미치는 영향

홍경애,송성준,송필순,유장걸,문두길 제주대학교 방사능이용연구소 1986 연구보고 Vol.2 No.-

암조건에서 생육시킨 보리(Hordeum valgare)잎의 생장점 부근에서 분리한 Protoplast가 적색광 처리에 의해서 팽윤되었고 적외선광에 의해서는 적색광 효과과 소멸되었다. 이 사실은 Protoplast의 팽윤이 Phytochrome에 의해서 조절됨을 시사하는 것이나 Phytochrome의 작용기작을 알기 위해서는 다각적인 연구가 필요하다. 실험결과로 부터 적색광 처리시간은 2분 적색광 처리후 배양시간은 2시간이 적당함을 알았다. Protoplast 배양액의 Sorbitol 농도에 따른 크기변화는 농도가 낮을수록 커졌으며 0.4M 이하에서는 Protoplast가 파괴되었다. Light effect on the size of protoplasts isolated from etiolated barley leaves was studied. Red light irradiation caused a swelling of protoplasts while little change in size found under the dark condition. Photoreversibility by red light and far-red light was found in protoplast swelling, indicating the involvement of phytochrome. Action mechanism of phytochrome on protoplast swelling should be clarified in aspect of growth regulators and intermediates involved. Two minute irradiation time and two hour incubation after red light treatment were found sufficient to induce protoplast swelling. The protoplasts were swollen according to the sorbitol concentration of incubation media but destroyed below 0.4M-sorbitol concentration.

Tufted Angioma와 유사한 소견을 보인 화농성 육아종

장경애,최정철,최지호,성경제,문기찬,고재경 대한피부과학회 1999 대한피부과학회지 Vol.37 No.6

Tufted angiomas are rare slowly progressive vascular lesions found typically in children and young adults, usually involving the trunk and neck. Microscopically, groups of capillary tufts, many uncanalized, were found dispersed at various levels in the dermis. Some authors regarded tufted angioma as a member of lobular capillary hemangiomas. We describe a pyogenic granuloma mimicking acquired tufted angioma on the lip in a 59-year-old woman. We suggest that a term lobular capillary hemangioma$quot; may be preferable in this case.

아세메타신 및 인도메타신의 혈장 중 동시분석법

조애리,문희경 德成女子大學校 藥學硏究所 2003 藥學論文誌 Vol.14 No.1

Acemetacin is a new potent non-steroidal anti-inflammatory compound which is used for the treatment of arthritis and rheumatic diseases. To establish an assay condition for a Bioequivalence study of acemetacin, a column liquid chromatographic (HPLC) method using UV detection for the determination of acemetacin and its metabolites indometacin in blood has been developed. The HPLC apparatus used in this study was a Waters 2695 Separation Module (Alliance) system. Samples were analyzed with Dual-λ-Absorbance Detector (UV254 nm). C_(18) (250×4.6mm, Luna 5μm, Phenomenex) column which maintained at 40℃, provided a good resolution. The mobile phase was composed of 0.02M 인산용액 (pH 4.5):MeOH=45:55. The flow rate was 1.4ml/min. Typical retention times with Luna column were 23, 31 and 34 min for flubiprofen (internal standard), acemetacin and indometacin, respectively. For the data manipulation, Waters Millennium program was employed. Calibration curves for the determination of acemetacin and indometacin in plasma showed a good linearity at a concentration range from 100ng/ml to 4000ng/ml(r²=0.999). The lower detection limits for both compounds were 100ng/ml.

범법간질환자와 정신질환자의 비교연구 : 범죄특성과 간질 Characteristics and Epilepsy in Criminal Acts

이상봉,박경우,김재문,이애영,정진상 대한신경과학회 1996 대한신경과학회지 Vol.14 No.1