Cochlear Implantation in the Elderly: Speech Performance, Associated Factor, Complication, and Surgical Safety

Oh Minji,Oh Eun Jung,Jung Boseung,Yoo Myung Hoon,Yoo Shin Young,Jung Da Jung,Lee Kyu-Yup 대한청각학회 2023 Journal of Audiology & Otology Vol.27 No.4

Background and Objectives: The guidelines for cochlear implantation (CIs) are expanding, and the number of CI procedures performed on the elderly is increasing. The purpose of this study was to analyze the results and safety of cochlear implantation in the elderly, as well as to evaluate the predictive factors on CI outcomes.Subjects and Methods: The study included 56 patients aged ≥40 years, who received CIs between 2009 and 2020. They were divided into two groups: 27 younger adults (40-64 years) and 29 elderly (>64 years). The study compared their pre- and postoperative speech perception and category of auditory performance (CAP) scores, surgical complications, and hospitalization periods. It also evaluated associated factors in the elderly group by examining categorical and continuous variables and postoperative CAP score.Results: There was a significant improvement in speech recognition tests (both word and sentence) and CAP scores in both groups compared to the pre-implantation scores (<i>p</i><0.001). Postoperative results were slightly lower in the elderly group than in younger adults for sentence recognition and CAP scores, except for word recognition. No significant associated factors were found on postoperative CAP scores, except for etiology. Postoperative CAP significantly improved in the sudden hearing loss group compared to the groups with other etiologies (<i>p</i>=0.045). The elderly group had more comorbidities than that in the younger adult group (<i>p</i>=0.026), but there were no significant differences in postoperative complications and hospitalization periods.Conclusions: While speech recognition and CAP scores were relatively lower in the elderly group compared to the younger adults, the elderly group showed significant improvements in audiological results after CI. Moreover, CI was safe and well tolerated in elderly patients.

Immune-mediated hemolysis after administration of human intravenous immunoglobulin in a dog: a case report

Minji Kim,Young Ju Kim,Hyeona Bae,Rankyung Jung,Minjeong Kang,Sumin Cha,Kyu-Woan Cho,Dong-In Jung,DoHyeon Yu 대한수의학회 2023 大韓獸醫學會誌 Vol.63 No.3

A 10-year-old spayed female Maltese presented with purpura and hematemesis. Initial laboratory evaluation revealed immune-mediated thrombocytopenia, but evidence of hemolytic anemia was not identified. Three milligrams of human intravenous immunoglobulin (hIVIG) was administered for 3 hours following prednisolone and mycophenolate mofetil. A pale mucous membrane was identified, and the packed cell volume decreased by 3%. Blood film examination revealed significant spherocytosis with auto-agglutination. Blood transfusions and immunosuppression were continued for 4 days, and hIVIG was discontinued. This report describes a case of increased immune-mediated hemolysis after hIVIG administration, possibly due to new-onset immune-mediated hemolytic anemia or enhanced immunogenicity.

Rehabilitation in Children With Sclerodermoid Chronic Graft-Versus-Host Disease: Case Series

Minji Jung,성인영,Eun Jae Ko 대한재활의학회 2019 Annals of Rehabilitation Medicine Vol.43 No.3

Joint contracture in chronic graft-versus-host disease (cGVHD) is refractory to treatment, and tends to deteriorate gradually over time. There is scant clinical research focusing on timing and intensity of rehabilitation on joint contractures in children with sclerodermoid cGVHD after hematopoietic stem cell transplantation. We retrospectively reviewed rehabilitative therapeutic effects in 6 children with sclerodermoid cGVHD, whose clinical records documented their condition, before and after rehabilitation therapies. Three children who started treatment within a mean of 2 months after the onset of joint symptoms, and who underwent home-based exercise twice daily for 30 minutes showed more prominent improvement in range of motion compared with the other 3 children, who started rehabilitation therapy later than 6 months after onset of joint symptoms, without regular home-based exercise.

High Resolution Manometry versus Video Fluorography for Evaluating Dysphagia in Patients with Inflammatory Myopathy: A Pilot Study

Minji Jung,Kyoung Hyo Choi,Kyeong Joo Song,Kee Wook Jeong,Yong-Gil Kim 대한연하장애학회 2020 대한연하장애학회지 Vol.10 No.1

Objective: Dysphagia has been reported to occur in patients with inflammatory myopathy (IM). Although high-resolutionimpedance manometry (HRIM) provides precise information regarding the pharyngeal pressure, it has not yetbeen used for assessing dysphagia in routine clinical practice. This study determined whether the results of HRIMfor evaluating deglutition disorders in patients with IM could reflect an abnormality that can’t be identified by avideo fluoroscopic swallowing study (VFSS). Methods: We reviewed both VFSS and HRIM results of nine patients with IM, four of whom presented with globussensation. Results: Cricopharyngeal muscle dysfunction was noted in all four patients with globus sensation, and the upperesophageal sphincter residual pressure (UESRP) was higher (≥8 mmHg) in the patients with pharyngeal residue. Using VFSS and HRIM, we demonstrated that dysphagia in patients with IM may arise owing to failed relaxation ofUES or decreased hyolaryngeal excursion. Conclusion: In conclusion, UES-RP values of ≥8 mmHg indicate the presence of pharyngeal residue and globussensation in patients with IM. HRIM provided a comprehensive assessment of the mechanisms of dysphagia, andHRIM facilitated recognizing subtle abnormalities in pharyngeal contraction and UES function. HRIM can overcome thelimitations of VFSS by allowing clinicians to perform objective measurements in patients with IM.

Development of a semi-quantitative food frequency questionnaire for dietary intake of elementary school children: data from the Seventh Korea National Health and Nutrition Examination Survey

Jung Minji,Ha Eunhee,Kwon Oran,Kim Hyesook 한국영양학회 2023 Nutrition Research and Practice Vol.17 No.4

BACKGROUND/OBJECTIVES: In Korea, studies of diet in elementar y school children are hindered by the need for a comprehensive dietar y assessment tool. Thus, the aim of this study was to develop a semi-quantitative food frequency questionnaire (FFQ) for Korean elementar y school children. SUBJECTS/METHODS: The 24-h recall data for 1,624 subjects aged 6−11 yrs from the seventh Korea National Health and Nutrition Examination Sur vey were used to extract the items included in the questionnaire. The FFQ items were developed by selecting major dishes based on the results of nutritional contribution and between-person variability for energy and 14 nutrients (carbohydrate, protein, fat, crude fiber, calcium, phosphorous, iron, sodium, potassium, vitamin A, thiamin, riboflavin, niacin, and vitamin C). We selected the major dishes with over 90% of the total contribution to each nutrient and with over 90% of the accumulated R2 for each nutrient. Among the 452 dishes, we selected 248 dishes contributing more than 1% of the total consumption. RESULTS: Finally, the FFQ included 107 items combined from 248 dishes based on nutrient profile and recipe. The FFQ items accounted for an average of 88.6% of the energy, 14 nutrient intakes, and 91.4% of the between-person variability. Quantities of dietar y intake were assessed by 9 categories of frequency and 3 categories of portion size. Percentages of coverage for energy, protein, fat, carbohydrate, and calcium were 90.2%, 87.8%, 89.9%, 90.8%, and 88.7%, respectively. CONCLUSIONS: We developed a dish-based, semi-quantitative FFQ comprising 107 items for Korean elementar y school children aged 6 to 11. Further studies are needed to evaluate the reproducibility and validity of this FFQ for elementar y school children.

A comparison of methods for the measurement of adherence to antihypertensive multidrug therapy and the clinical consequences: a retrospective cohort study using the Korean nationwide claims database

Minji Jung,Eunjung Choo,Sukhyang Lee 한국역학회 2023 Epidemiology and Health Vol.45 No.-

OBJECTIVES: In observational studies, the methods used to measure medication adherence may affect assessments of the clinical outcomes of drug therapy. This study estimated medication adherence to multidrug therapy in patients with hypertension using different measurement methods and compared their impacts on clinical outcomes. METHODS: This was a retrospective cohort study using the Korean National Health Insurance Service–National Sample Cohort database (2006-2015). Adults diagnosed with hypertension who initiated multidrug antihypertensive therapy in the index year 2007 were included. Adherence was defined as over 80% compliance. Adherence to multidrug antihypertensive therapy was measured in 3 ways using the proportion of days covered (PDC) with 2 approaches to the end-date of the study observations: PDC with at least one drug (PDCwith≥1), PDC with a duration weighted mean (PDCwm), and the daily polypharmacy possession ratio (DPPR). The primary clinical outcome was a composite of cardiovascular and cerebrovascular disease-specific hospitalizations or all-cause mortality. RESULTS: In total, 4,226 patients who initiated multidrug therapy for hypertension were identified. The mean adherence according to the predefined measurements varied from 72.7% to 79.8%. Non-adherence was associated with an increased risk of a primary outcome. The hazard ratios (95% confidence intervals, CIs) primary outcomes varied from 1.38 (95% CI, 1.19 to 1.59) to 1.44 (95% CI, 1.25 to 1.67). CONCLUSIONS: Non-adherence to multidrug antihypertensive therapy was significantly associated with an increased risk of a primary clinical outcome. Across the varying estimates based on different methods, medication adherence levels were similar. These findings may provide evidence to support decision-making when assessing medication adherence.

Differentiation of printing paper using stable isotope ratio mass spectrometry

Minji Jung,Byeongyeol Song,Seongshin Gwak,Songhie An,Nam Yee Kim,Geummun Nam 한국분석과학회 2017 학술대회논문집 Vol.2017 No.11

Poster Session : PS 1289 ; Pulmonology : Rapid Pathogen Identifi cation Using MALDI-TOF MS for Critically Ill Patients with Pneumonia

( Minji Kim ),( Sang Hee Lee ),( Jung Sup Eom ),( Eun Jung Cho ),( Mi Hyun Kim ),( Kwang Ha Lee ),( Ki Uk Kim ),( Hye Kyung Park ),( Min Ki Lee ),( Jeong Ha Mok ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

Background: Rapid pathogen identification and appropriate antibiotics therapy is important to treat critically ill patients. This study was conducted to evaluate the usefulness of Matrix-Assisted Laser Desorption/Ionization-Time of fiight Mass spectrometry (MALDI-TOF MS) for rapid pathogen identification for critically ill patients with pneumonia. Methods: We conducted a retrospective study in the intensive care unit (ICU) at Pusan National University Hospital in Korea from May 2012 to February 2014. Patients who performed microbial culture and organism identification of endotracheal aspirate while receiving ventilator care were enrolled. Results: A total 50patients were included final analysis. Pathogen identi. cation was performed using MALDI-TOF MS in 27patients (MS group) and conventional methods in 23patients (Conventional group). There were no differences in demographic characteristics and disease severity between two groups. When comparing two groups, the average time between endotracheal aspirate sample collection and pathogen identification (with antibiotics susceptibility test result) was shorter in MS group than conventional group (51.9 ± 10.8hr vs. 70.5 ± 28.2hr, p < 0.05). Thirty-seven patients changed antibiotics according to the identi. cation results (21patients in MS group, 16patients in conventional group). The average time between sample collection and antibiotics change was shorter in MS group than conventional group (55.8 ± 10.6hr vs. 74.9 ± 29.8hr, p < 0.05). However, there were no significant differences in duration of mechanical ventilation, length of hospital stay and hospital mortality between two groups. Conclusion: Pathogen identification and antibiotics change was faster when using MALDI-TOF MS in critically ill patients with pneumonia. Further investigation is needed to evaluate the impact of rapid pathogen identification on clinical courses of critically ill patients.

한류 및 한국 화장품의 제품이미지가 해외직접구매의도에 미치는 영향: 중국 소비자를 대상으로

정민지 ( Jung Minji ),정재은 ( Chung Jae-eun ),양희순 ( Yang Heesoon ) 한국소비자학회 2018 소비자학연구 Vol.29 No.1

한국 화장품의 대 중국 수출은 세계적인 경기 침체 및 한·중 간의 외교적 마찰에도 불구하고 꾸준히 증가하고 있으며, 중국의 전자상거래 시장이 빠르게 성장하면서 국내 역직구 시장 확대에 대한 기대감이 상승되고 있다. 본 연구는 중국 거주 소비자를 대상으로 한류, 한국 화장품의 제품이미지, ‘Kmall24’ 웹사이트의 지각된 유용성 및 이용편리성을 측정하여 한국 화장품에 대한 해외직접구매의도에 미치는 영향을 실증적으로 분석하였다. 이를 위해 만 20세 이상의 남·여 소비자를 대상으로 온라인 설문조사를 실시하였으며, 총 250부가 최종분석에 활용되었다. 분석방법은 Amos 21.0을 활용하여 구조방정식모형 분석을 실시하였다. 본 연구의 결과를 요약하면 다음과 같다. 첫째, 응답자들의 한국제품에 대한 온라인 구매는 주로 중국 온라인 플랫폼을 통해 이뤄지는 것으로 나타났으며, 한국제품 중 화장품 및 뷰티제품, 의류를 가장 많이 구매하는 것으로 나타났다. 둘째, 가설검증결과 한류는 한국 화장품의 제품이미지와 한국 온라인 쇼핑몰의 지각된 이용편리성에 긍정적인 영향을 미치는 것으로 나타났으며, 한국 화장품의 제품이미지는 한국의 온라인 쇼핑몰의 지각된 이용편리성에 긍정적인 영향을 미치는 것으로 나타났다. 그러나 한류 및 제품이미지는 해외직접구매의도에 대한 직접적인 영향은 유의하지 않았으나 지각된 이용편리성 및 지각된 유용성을 통해 간접적으로 영향을 주는 것으로 파악되었다. 마지막으로 한국의 온라인 쇼핑몰의 지각된 이용편리성이 지각된 유용성에 긍정적인 영향을 미쳤으며, 지각된 유용성이 한국의 온라인 쇼핑몰을 통한 한국 화장품의 구매의도에 긍정적인 영향을 미친 것으로 드러났다. 이에 본 연구는 글로벌 전자상거래 시장에서 해외소비자의 한국제품 구매행동에 대한 이해를 높이고 중국시장에 중소기업의 소비재 수출 판로 확대를 위한 전략을 수립하는데 도움이 될 거라 기대된다. Cross-border shopping is defined as domestic consumers’ direct purchase of foreign products via online platforms, Korean cross-border shopping market exhibited extraordinary growth. According to the Korean Customs Service Office(2017), Korean e-commerce exports reached 2.3 trillion won in 2016 and increased by 84 percent year-on-year, and China is Korea’s largest e-commerce export market. Furthermore, due to the increasing popularity of the Korean Wave, the demand for Korean consumer-goods among foreign consumers has increased. The purpose of this study is to examine the effects of Korean wave, product image, perceived ease of use and perceived usefulness on Chinese consumers’ cross-border shopping intention toward Korean cosmetics. Our data were collected from 250 consumers older than 20 years of age and who live in China using a quota sampling method. An existing online shopping mall, ‘Kmall24’ website, was utilized to evaluate how participants perceive usefulness, ease of use and cross-border shopping intention. For the analysis, SPSS was used to conduct frequency analysis and reliability test, and AMOS 21.0 was used to test confirmatory factor analysis(CFA) and structural equation modeling(SEM). Results of the study were summarized as follows. First, Korean wave was found to have positive effects on product image and perceived ease of use. Second, product image had a positive relationship with perceived ease of use. Third, Korean wave and product image had indirect effects on cross-border shopping intention toward Korean cosmetics. Forth, perceived ease of use had a positive effect on perceived usefulness, which, in turn, was positively related to cross-border shopping intention toward Korean cosmetics. The results help understand factors influencing Chinese consumers’ purchase intentions in cross-border e-commerce and suggest that it is important for Korean cosmetics firms to develop effective marketing strategies emphasizing Korean wave and product image of Korean cosmetics to enhance export performances.

음압격리병상에서의 환기방식에 따른 토출입자의 거동 특성에 대한 해석적 연구

정민지(Minji Jung),윤홍익(Hong Ik Yoon),홍진관(Jin Kwan Hong) 대한설비공학회 2018 대한설비공학회 학술발표대회논문집 Vol.2018 No.6

This study investigates the influence of ventilation type on the transport characteristics of coughing particles in Airborne Infection Isolation Room (AIIR), which is commonly called negative pressure isolation room. Computational Fluid Dynamics (CFD) was used to simulate the airflow and for tracing the behavior of particles. The results show that the airflow pattern has a significant influence on the particle dispersion characteristics. Sidewall exhaust system is more effective than ceiling exhaust system for particle removal. Although it is an isolation room that produces unidirectional flow, coughing particles can spread to the whole room and a large number of particles can be deposited onto patient, bed, side rails, healthcare worker, ceiling, floor, and sidewall.