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      • KCI등재

        보건소를 이용하는 지역주민의 건강 행위와 건강관련 체력간의 관계

        전미양,최명애,이인숙,김태수,김의숙,박선홍 대한보건협회 2002 대한보건연구 Vol.28 No.3

        The purpose of this study is to identify relationship health behavior and health related physical fitness in order to provide the basic data for health promotion program for community people. The study was conducted 299 people, during the period from June 1, 2000 to October 30, 2000. The result are as follows. 1. Female comprised was 63.2%(189), while male comprised 36.8%(110). The age range of the subject were from 21 to 59 years old. The subject were aged 30s group 52.5%, 40s group 29.1%, 50s group 12.7%, 20s group 5.7%. Twenty subjects (6.7%) had experience smoking and one subject (0.3%) in female and nineteen subjects (6.4%) in male. Seventy-five subjects (25.1%) had experience drinking and twenty-nine subjects (9.7%) in female, and forty-six (15.4%) in male subjects. ninety-nine subjects had exercise and sixty subjects (20.1%) in female subjects and thirty-mine subject (13%) in male. 2. Body fat and flexibility were higher in female than male subjects, but cardioresperatory endurance, muscular strength and muscular endurance were higher in male than female subjects. 3. There were significant differences in body fat and muscular endurance between age group in both gender subjects, and in cardioresperatory endurance and muscular strength between the age group in male subjects. 4. No significant differences health related fitness between non-smoking and smoking group in both gender subjects. 5. No significant differences health related fitness between non-alcohol and alcohol group in both gender subjects. 6. For female subjects, muscular strength, muscular endurance and flexibility of the exercise group were significantly higher than those of the non exercise group. for male subjects, cardiorespiratory endurance of the exercise group were significantly higher than those of the non exercise group.

      • Southern Blot Hybridization법을 이용한 악성 림프종의 면역유전형에 관한 연구

        전호종,기근홍,김윤신,이미숙,이미자,장원재,장숙진,박영진,정춘해,정종훈,양성훈,이광민 조선대학교 1994 The Medical Journal of Chosun University Vol.19 No.2

        Immunogenotyping using gene rearrangement analysis has emerged as a precise laboratory aid in the diagnosis and classification of malignant Iymphoid neoplasms. The lineage and clonality of the malignant Iymphoid neoplasms can be identified by the demonstration of rearrangements of antigen receptor genes of the immunoglobulin and T-cell receptor genes. The analysis of the gene rearrangements on the malignant Iymphoid neoplasms are also useful as a sensitive unique clonal markers to detect early recurrence in patients with malignant Iymphoid neoplasms after treatment. To analyze the sensitivity and specificity of gene rearrangements in the diagnosis of malignant Iymphoid neoplasms. 24 cases of malignat Iymphoma were examined by Southern blot hybridization using CTβ-T cell receptor β chain gene-DNA probe and JH-immunoglobulin heavy chain gene-DNA probe. The results of the immunogenotypings using Southern blot hybridization disclosed high correlation between the immunophenotyping using immunohistochemical stain with monoclonal antibodies (B-cell Iymphoma 84.2%. T-cell Iymphoma 75% ). The analysis of the gene rearrangement of the angioimmunoblastic lymphadenopathy(AILD) and unclassifiable Iymphoma using immunohistochemical stain could resolve the monoclonality and lineage . Rearranged bands to the CTβDNA probe were observed in one case out of 2 cases of AILD. One case of unclassifiable Iymphoma showed rearranged bands to the CTβ DNA probe. There were no rearrangements in reactive follicular Iymphoid hyperplasia and paracortical Iymphoid hyperplasia. In conclusion, DNA gene rearrangement study should be applied to differentiate the clonality and cell lineage in the malignant Iymphoma with indistinctive immunophenotype.

      • KCI등재

        낙상예방 프로그램이 양로원 여성노인의 보행, 균형 및 근력에 미치는 영향

        전미양,최명애 대한기초간호자연과학회 2002 Journal of korean biological nursing science Vol.4 No.1

        Purpose:To determine the effect of the Fall Prevention Program(FPP) on gait, balance and muscle strength of elderly women at a nursing home. Methode:The subjects of this study consisted of 38 elderly women between the ages of 70 to 89 years living at a nursing home located in Seoul. Each of the experimental group and control group was composed of 19 subjects. The subjects in experimental group have participated in FPP for the 8 weeks which consisted of exercise, education and foot care. They started to exercise for 40 minutes per session, 3 sessions a week during the 1st week at 40% of age adjusted maximum heart rate. From the 2nd week to the 4th week, they increased the duration of exercise to 50 minutes per session and the intensity to 60% of age-adjusted maximum heart rate. They participated in 50 minutes at 60% of age-adjusted maximum heart rate from the 5th week to the 8th week. Each exercise session consisted of 10 minutes of warming-up exercise, 30 minutes of conditioning exercise and 10 minutes of cooling-down exercise. They participated in education for 20 minutes per week from the 1st week to the 4th week. Then they participated in a 30-minute foot care program per week from the 5th week to the 8th week. Gait, balance and muscle strength for each subject were measured before and after FPP. Gait was evaluated by step length, step width, gait speed and walking distance. Balance was measured by the duration of standing on one leg with their eyes closed and open each, and a get-up and go test. Grip strength was measured by hand dynamometer. Hip extensor and flexor strength, knee extensor and flexor strength and ankle plantarflexor and dorsiflexor strength were measured by manual muslce tester. Data was analyzed using SPSS from Windows. t-test and Chi square test were utilized as a homogeneity test. Repeated measure ANOVA was used to test the effect of FPP. Result:1) Step width significantly decreased, and step length, gait speed and walking distance significantly increased in the experimental group compared with the control group after FPP(p<.005). 2) There was no significant change in standing time on one leg with their eyes closed after FPP. The standing time on one leg with their eyes open and the time of “get-up and go” significantly decreased in the experimental group compared with the control group after FPP(p<.005). 3) Muscle strength-grip strength, hip extensor and flexor strength, knee extensor and flexor strength and ankle plantarflexor and dorsiflexor strength-significantly increased in the experimental group compared with the control group after FPP(p<.005). 4) There was no significant difference of frequency of fall between the experimental group and control group during the period of FPP. Conclusion:These results suggest that FPP can increase gait, balance and muscle strength of elderly women at a nursing home.

      • KCI등재후보

        일차성 Streptococcus pneumoniae 균혈증에 동반된 흉부 하행 대동맥염 1예

        전민혁,고옥배,정우진,최영준,이정훈,최상호,김미나,김양수,우준희,류지소 대한감염학회 2005 감염과 화학요법 Vol.37 No.5

        페렴구균에 의한 대동맥염은 국내에서 1예만 보고될 정도로 매우 드문 감염증이다. 저자들은 원발성의 폐렴구균혈증에 합병된 페렴구균 대동맥염 환자 1례를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Bacterial aortitis is rare and without surgical intervention, it usually leads to uncontrolled sepsis or catastrophic hemorrhage, ultimately, resulting in death. In the postantibiotic era, the dominant infecting organisms are Staphylococcus aureus and Salmonella spp.. In spite of frequent pneumococcal bacteremia, vascular seeding is rare and there is only one published report in Korea. We describe a 77-year-old female with primary pneumococcal bacteremia followed by aortitis of the descending aorta, which was successfully treated by aneurysmectomy, wide excision of periaortic tissue, aortobiiliac bypass via prosthetic graft, and antibiotic therapy.

      • 알코올의 섭취가 흰쥐의 혈액과 간의 지질대사에 미치는 영향

        이명숙,김영연,김효숙,김매하,전진순,서진숙,송선미,양영재,윤원손,이미라,이효영,정승현 誠信女子大學校 生活文化硏究所 2004 生活文化硏究 Vol.18 No.-

        To investigate the effects of ethanol on the lipid metabolism in blood and liver, twenty one male Sprague Dawley rats had orally taken the 25% alcohol and 50% alcohol by 5g per Kg of weight during 3 weeks after the adjusting period. For the energy balance, 85% sucrose and 45% sucrose was added in control group and 25% alcohol group each. The weight was reduced by alcohol treatment according to the levels, otherwise the weight of liver and heart was little increased in alcohol groups rather than in control without significance. Moreover, RBC, WBC, hemoglobin and hematocrit were increased by alcohol treatment according to the levels without significance. Otherwise, adjusted bilirubin levels by 100g of weight was significantly increased by alcohol treatment dose dependently. Alcohol induced RBC degradation and increased circulated bilirubin because of liver damage. For blood lipid profiles, blood cholesterol was increased in 50% of alcohol group compared to that of 25% and control groups, otherwise, blood triglycerides (TG) was increased by 30% in 25% alcohol groups rather than in control but not significantly different. The hepatic lipid composition, cholesterol levels in alcohol treatment groups was lower than those in control. The hepatic TG was not influenced by alcohol treatment. The two reasons of decreasing hepatic lipids were suggested by 85% sucrose of control for energy balance more synthesized cholesterol and TG than those in 25 or 50% alcohol groups, and by cholesterol and TG could not be synthesized because of liver damage from alcohol.

      • SCIESCOPUSKCI등재

        Preparation and Evaluation of Ketorolac Tromethamine Gel Containing Genipin for Periodontal Diseases

        Yang, Jeon-Heon,Yun, Mi-Young,Kim, Dae-Keun,Kim, Mi-Jeong,Kim, Young-Il,Kim, Tae-Youl,Yang, Kyu-Ho,Shin, Sang-Chul 대한약학회 2007 Archives of Pharmacal Research Vol.30 No.7

        Ketorolac tromethamine gel (KT gel) and ketorolac tromethamine gel containing genipin (KTG gel) were prepared and their therapeutic effects on periodontitis were evaluated. The skin permeation rate of ketorolac from the KT gel and KTG gel was $5.75{\pm}0.53$ and $5.82\;{\pm}\;0.74\;{\mu}g/cm^{2}/h$, respectively. The skin permeation rate of genipin from the KTG gel was $10.13\;{\pm}\;1.47\;{\mu}g/cm^2/h$. The tensile strength of the KTG gel was larger than the KT gel. After 4 weeks, the periodontal pocket depth of the KTG gel group ($3.22\;{\pm}\;0.20\;mm$) significantly decreased compared with the non-treated group ($4.50\;{\pm}\;0.25\;mm$) and the KT group ($3.84\;{\pm}\;00.26\;mm$). The KTG gel did not induce separation of the stratum corneum and subcutaneous tissue, and the collagen layers of the cerium were closer, more fibrous, and showed longer connections than in the other groups. The KTG gel appears to be effective against gingivitis in the periodontal pocket through its increased anti-inflammatory activity and the crosslinking of genipin with the biological tissue.

      • Effect of 4-week regular dance movement on the physiopsychological changes in young women

        Jeon,Mi-Yang,CHOE,Myoung-Ae,Cho,Mi-Kyoung 서울대학교 간호대학 간호과학연구소 1996 간호학 논문집 Vol.10 No.1

        4주간의 규칙적인 율동적 동작수행이 젊은 여성의 생리, 심리적 변화에 미치는 효과를 밝힐 목적으로 연구에 참여하기를 원하는 10명의 여대생을 대상으로 1주 3회 1일 30분 4주에 걸쳐 규칙적으로 율동적 동작을 수행하도록 하였다. 율동적 동작프로그램은 Herber의 동작지침을 토대로 머리에서 발끝까지 움직이는 동작이 되게 하였고 준비동작으로 시작하여 빠른 동작, 스트레칭동작, 원을 그려 마주보면서 실시하는 자유동작, 발레동작으로 구성되었다. 규칙적인 율동동작 수행적과 4주 수행후 생리적 변화로 체중, 사지둘레 및 근력, 안정시 혈압과 심박동수를 측정하였고 심리적 변화로 스트레스 반응을 측정하였으며, 4주간의 율동적 동작 수행후 주관적 느낌을 면담하여 어의반응을 분석한 결과 다음과 같은 결론을 얻었다. 4주간의 규칙적인 율동적 동작 수행 후 하퇴 둘레가 유의하게 증가하였고, 우울의 평균점수가 유의하게 감소하였으며, 율동적 동작에 대한 주관적 느낌의 어의 반응이 긍정적이었다. 이상의 결과로 보아 4주간의 규칙적인 율동적 동작 수행으로 하퇴둘레가 증가하고 우울이 감소되며, 율동적 동작에 대한 주관적 느낌의 어의 반응이 긍정적이다라고 할 수 있겠다.

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