치아미백제의 미백효과에 관한 연구

이용근,이흥수,이성재,방기숙,오상엽 원광대학교 생체재료·매식연구소 1996 원광생체재료·매식 Vol.5 No.2

Human teeth vary widely in color. Practitioner and patients are concerned with preventing and correcting discolored or dark teeth to achieve and maintain stain-free, white teeth. Tooth brushing cannot after tooth color but it can remove adherent films and stains. Esthetics of natural dentition can be improved by bleaching and this process can be applied to intrinsically and extrinsically stained teeth. The need for a brighter, more attractive smile has made rapid growth in the marker for tooth whiteners. There is no doubt these products work as whiteners, at least on mild to moderate stains, but the safety of these products are unclear. In this experiment, the effect of tooth whitener application on the color of extracted human enamel was measured. RMS, RMT and NWT were used as tooth whiteners, and tooth paste(ETQ) and hydrogen peroxide solution(HPO) were used as controls. 35 caries-free extracted human molars were embedded and polished with the exposed enamel diameter of 4 mm. The tooth whiteners and control agents were according applied to the manufacturers' instructions of clinically simulated procedures for eight weeks, and measurements were repeated every two weeks. CLELAB color difference(ΔE^*) was measured using Differential Colorimeter(Model TC-6FX, Denshoku Co., Japan). The results were are follows ; 1. After application of tooth whiteners and controls for eight weeks, the color change of all groups were not significantly different from each other (p>0.01). But after application of agents for 2 weeks and four weeks, the color difference of NWT applied group and HPO applied group were significantly higher than those of others(p<0.01). 2. The application of tooth paste and paste type tooth whitener made gradual color change, but hydrogen peroxide gel type whitener and hydrogen peroxide solution made rapid color change during initial application period.

농기계의 보관 관리 실태에 관한 연구

이규승,김성엽,박원엽 성균관대학교 생명공학연구소 2001 生命工學硏究 Vol.7 No.1

This study was conducted to analyze the storage and management status of major farm machinery, and to present the basic information for the construction of multipurpose storage housing suitable to the individual farmers by identifying current problems. The average farm area of the surveyed farmers was 4.25ha, which represents relatively higher than the average of whole country. The mechanization rate for paddy farming was 98%. so, the individual storage housing should be concentrated on the farm machinery utilized in paddy farming. The annual operating time for the seasonal farm machinery(such as combine and rice transplanter) were showed high difference between farmers and machines. For the rice transplanter, the highest portion of annual operation time was 1∼10 days as 71%, and for the combine, that was over 20 days as 36% and the second was 16∼20 days as 23%. The average difference in repairing cost for combine between the farmers with and without common storage housing was 100,000 won. The percent of storaging farm machinery in the open field for farmers without housing were 44% for power tiller, 16% for farm tractor, 21% for rice transplanter, 10% for combine. Each farmer had the individual temporary simple housing with various kinds and structure. Most of the farmers, 63.7%, want to use the farm machinery storage housing as multipurpose utilization. Twenty nine percent of farmers want to use the farm machinery storage housing any for storaging purpose. And, most farmers prefer near the farm house as suitable position of housing, and prefer the area of 132∼198㎡ for storage housing. The current problems on common storage housing were insufficient area(44.8%), no problem(29%) improper position, excessive construction cost, inconvenient entrance, etc.

한국 천식아동의 기질특성

김승태,최성구,김상엽,정유숙,홍성도,김선우,이상일,이흥재 大韓神經精神醫學會 1997 신경정신의학 Vol.36 No.6

이 연구의 목적은 기관지 천식아동의 기질특성을 알아보기 위한 것이다. 저자중 일인의 예비연구에 의하면 천식아동집단은 습진이나 알러지성 비염 등의 만성질환을 가진 아동집단이나 정상아동과는 다른 기질특성을 갖는다. 세 살에서 일곱 살 사이의 정상아동과 기관지 천식을 앓는 아동 85명의 어머니들에게 한국판"부모기질설문(Parental Temperamental Questionnaire)"을 완성하도록 하여 기질을 측정하였다. 기질의 9가지 범주 및 요인 A점수를 비교하기 위하여 비모수적 통계법을 사용하였으며, 아동들의 기질진단을 비교하기 위하여 Chi-square통계법을 사용하였다. 그 결과 천식을 앓는 여아집단은 정상 여아집단에 비해 적응성과 반응의 역치 범주에서 통계적으로 유의하게 낮았다. 또 정상아동집단의 11%가 기질진단적으로 양육곤란형인 반면 천식아동집단은 22%를 차지했다. 두 집단은 기질진단면에서도 통계적으로 유의한 차이를 보였다. 이와 같은 결과는 천식아동에 특징적인 기질양상이 있음을 시사한다. 기질양상의 조기발견은 부모들에게 천식아동의 건강한 발달을 이해하고 행동장애 고위험집단인 만성질환을 앓는 소아들에게 적절한 양육을 제공하는데 도움을 줄 것이다. The objective of this study was to determine temperamental characteristics of children with bronchial asthma. An earlier preliminary study(Kim SP, Ferrara A, Chess 5, 1980) results show that the asthmatic children, as a group, are significantly different from two other control groups(1. children with eczema, allergic rhinitis, or both without asthma : Ⅱ. normal healthy children in their temperamental profile). The parents of 85 Korean children with bronchial asthma, ages 3 to 7 years, completed the Korean version of Parental Temperamental Questionnaire developed by Thomas and Chess. The data collected were of ordinal type, ranked from 1 to 7 and the non-parametric Mann-whitney U Test was utilized. Any child with a suspected history or diagnosis of premature birth, organic brain syndrome, mental retardation, childhood psychosis, congenital physical anomaly, hereditary disease or any other medical or surgical conditions, other than asthma, requiring continuous physicians care was excluded from the study population. The results showed that asthmatic female children were characterized by lower adaptability and lower threshold of responsiveness. And 22% of asthmatic children were of the difficult type, compared to 11% of normal children. Both groups were statistically different in terms of temperamental constellation. The findings strongly suggest the existence of a distinct temperamental profile of asthmatic children. Early detection of the profile may be of great value for parents and child health care providers in understanding the asthmatic children's correct developmental needs and in determining appropriate parenting approaches for the chronically ill children at the risk of behavioral disorder.

Effect of house dust mite on neutrophil apoptosis by cytokine secretion in lymphocytes

Lee, Na Rae,Lee, Ji-Sook,Baek, Seung Yeop,Kim, Da Hye,Gu, Ayoung,Kim, Seong Yeol,Lee, Soo Jin,Kim, In Sik THE KOREAN SOCIETY OF TOXICOGENOMICS AND TOXICOPRP 2016 MOLECULAR AND CELLULAR TOXICOLOGY Vol. No.

Although extract of Dermatophagoides farinae (DF) alone had no effect on neutrophil apoptosis, it inhibited neutrophil apoptosis in neutrophils cocultured with lymphocytes in both normal and allergic subjects. DF showed a stronger inhibition on the apoptosis of allergic neutrophils cocultured with allergic lymphocytes than that of normal neutrophils cocultured with normal lymphocytes. DF induced the secretion of IL-6, IL-8, MCP-1, and GM-CSF of the normal and allergic lymphocytes. The cytokine secretion due to DF in allergic lymphocytes is higher than in normal lymphocytes. The cytokine secretion of normal and allergic lymphocytes induced by DF was suppressed by PAR2i, a PAR2 inhibitor, LY294002, a PI3K inhibitor, AKTi, an Akt inhibitor, PD98059, an ERK inhibitor, and BAY-11-7085, an <TEX>$NF-{\kappa}B$</TEX> inhibitor. Phosphorylation of ERK induced by DF was suppressed by PAR2i, LY294002 and AKTi, and <TEX>$NF-{\kappa}B$</TEX> activity due to DF was inhibited by PAR2i, LY294002, AKTi, and PD98059.

Identification and Characterization of a High Extracellular Protease Produced Bacillus subtilis JSY-67 Isolated from MeJu

Seong-Yeop Jeong,Sung-Wao Jo,Eun-Sil Lee,Dae-Ook Kang,Do-Youn Jeong,Jung-Mi Lee 한국식품영양과학회 2012 한국식품영양과학회 학술대회발표집 Vol.2012 No.10

<i>Paenalcaligenes hermetiae</i> sp. nov., isolated from the larval gut of <i>Hermetia illucens</i> (Diptera: Stratiomyidae), and emended description of the genus <i>Paenalcaligenes</i>

Lee, Youn Yeop,Lee, Jae Kook,Park, Kwan Ho,Kim, Seo-Yeon,Roh, Seong Woon,Lee, Sang-Beom,Choi, Youngcheol,Lee, Sung-Jae International Union of Microbiological Societies 2013 International journal of systematic and evolutiona Vol.63 No.11

<P>A novel Gram-stain-negative, facultatively anaerobic, non-motile and short rod-shaped bacterium, strain KBL009<SUP>T</SUP>, was isolated from the larval gut of <I>Hermetia illucens</I>. Strain KBL009<SUP>T</SUP> grew optimally at 37 °C, at pH 6.0 and with 1–2 % (w/v) NaCl. The 16S rRNA gene sequence of strain KBL009<SUP>T</SUP> showed 97.6 % similarity to that of <I>Paenalcaligenes hominis</I> CCUG 53761A<SUP>T</SUP> indicating its classification with the genus <I>Paenalcaligenes</I>. The major fatty acids were cyclo-C<SUB>17 : 0</SUB>, C<SUB>16 : 0</SUB> and summed feature 2 (comprising C<SUB>14 : 0</SUB> 3-OH/iso-C<SUB>16 : 1</SUB>). The respiratory quinones were ubiquinone-8 (Q-8), predominating, and a minor amount of Q-7. The polar lipids were diphosphatidylglycerol, phosphatidylethanolamine, phosphatidylglycerol, one unknown aminolipid and five unknown polar lipids. The polyamine pattern contained predominantly putrescine and relatively high amounts of spermidine. The betaproteobacterial-specific 2-hydroxyputrescine could only be detected in trace amounts. The G+C content of genomic DNA was 56.1 mol%. Results from DNA–DNA hybridization with <I>P. hominis</I> KCTC 23583<SUP>T</SUP> unambiguously demonstrated that strain KBL009<SUP>T</SUP> represents a novel species in the genus <I>Paenalcaligenes</I>. Based on phenotypic, genotypic and phylogenetic characterization, the novel species <I>Paenalcaligenes hermetiae</I> sp. nov. is proposed. The type strain is KBL009<SUP>T</SUP> ( = KACC 16840<SUP>T</SUP> = JCM 18423<SUP>T</SUP>). An emended description of the genus <I>Paenalcaligenes</I> is also provided.</P>

Poster Session 2 : Oral Presentation ; Neurobiology : The F-actin/microtubule crosslinker Shot is a platform for calcium-sensitive, Krasavietz-mediated translational regulation of multiple axon guidance and extension events

( Seong Soo Lee ),( Min Yeop Nahm ),( Seung Bok Lee ) 생화학분자생물학회 2005 62회 KSBMB Annual Meeting in 2005 Vol.- No.-

Poster Session 2 : The F-actin/microtubule crosslinker Shot is a platform for calcium-sensitive, Krasavietz-mediated translational regulation of multiple axon guidance and extension events

( Seong Soo Lee ),( Min Yeop Nahm ),( Seung Bok Lee ) 생화학분자생물학회 2005 생화학분자생물학회 춘계학술발표논문집 Vol.2005 No.-

자동 논리 회로도 생성기의 분할과 배치에 관한 연구

김성엽(Seong-Yeop Kim),최재선(Jae-Seon Choi),이봉규(Bong-Kyu Lee),이일주(Il-Ju Lee),김문덕(Mun-Deok Kim),한정우(Jung-Woo Han),정재조(Jea-Jo Jung),이철원(Chul-Won Lee),임인칠(In-Chil Lim) 한국정보과학회 1994 한국정보과학회 학술발표논문집 Vol.21 No.2A

본 논문에서는 네트리스트로부터 자동 논리도 생성기를 개발하기 위해 고찰해야 할 여러 문제들을 살펴보며 실제로 자동 논리도 생성기의 여러 단계 중 분할과 배치에 관한 알고리즘을 제시하였다. 일반 회로 중에서 빈번히 사용되는 정규회로 및 FF등을 “정규 회로의 인식 기법” 및 “Clustering Technique”을 사용하여 인식하며, 인식된 클러스터를 신호선의 흐름에 따라 지역적 배치 및 전역적 배치를 수행함으로써 기존의 열 중심 배치의 자동 논리 회로도 생성기에서 미흡했던 검증과 수정의 용이함 및 미적으로 우수한 논리 회로도 생성을 해결 할 수 있었다.

마찰열을 고려한 디스크 브레이크 스퀼 해석

이성엽(Seong-Yeop Lee),최주호(Joo-Ho Choi),강진혁(Jin-Hyuk Gang) 대한기계학회 2016 대한기계학회 춘추학술대회 Vol.2016 No.12

In this study, complex eigenvalue analysis is conducted considering frictional heat to predict the squeal noise of the brake system with more accuracy. The finite element analysis software ABAQUS is used to calculate the frictional heat generation and dynamic instability. Modal analyses and experimental modal tests of the brake disc components are performed to ensure the validity of the finite element model. As opposed to the previous studies that employed uniform temperatures for simplicity, the analytical temperature distribution is obtained by using a thermal-structure coupled field analysis in this study. The distribution is compared with the real measurements of the disc surface temperature during the squeal noise test. Finally, the effect of applying the temperature distribution is examined by comparing with the results by assuming the uniform temperatures.