New and noteworthy species of the lichen genus <i>Lecanora</i> (Ascomycota; <i>Lecanoraceae</i>) from South Korea

LÜ,, Lei,JOSHI, Yogesh,ELIX, John A.,LUMBSCH, H. Thorsten,WANG, Hai Ying,KOH, Young Jin,HUR, Jae-Seoun Cambridge University Press 2011 The Lichenologist Vol.43 No.4

<B>Abstract</B><P>Two new species, <I>Lecanora hafelliana</I> L. Lü, Y. Joshi & Hur and <I>L</I>. <I>loekoesii</I> Y. Joshi, L. Lü & Hur, are described as new to science from South Korea and eight species, <I>L. campestris</I> (Schaer.) Hue, <I>L. cenisia</I> Ach., <I>L. nipponica</I> H. Miyaw., <I>L. perplexa</I> Brodo, <I>L. plumosa</I> Müll. Arg., <I>L. polytropa</I> (Hoffm.) Rabenh., <I>L. subrugosa</I> Nyl. and <I>L. sulcata</I> (Hue) H. Miyaw., are recorded from South Korea for the first time. <I>Lecanora hafelliana</I> is characterized by the presence of hafellic acid, which is reported for the first time in this genus, while <I>L. loekoesii</I> is characterized by multispored asci and a thallus containing norstictic acid.</P>

Effects of Free-range Farming on Carcass and Meat Qualities of Black-feathered Taiwan Native Chicken

Cheng, F.Y.,Huang, C.W.,Wan, T.C.,Liu, Y.T.,Lin, L.C.,Lou Chyr, Chu-Ying Asian Australasian Association of Animal Productio 2008 Animal Bioscience Vol.21 No.8

The effects of free-range farming, compared to a conventional production system, on carcass and meat qualities were studied using black-feathered Taiwan native chickens. Twenty 16-week old females were purchased separately from a free-range farm and a conventional production farm and used for this study. The results showed similarities in the live weight (roughly 2.1 kg), dressing percentage (69%) and meat percentage (19%) of deboned leg quarter. Significant differences (p<0.05) found for the free-range chickens included: a higher percentage of meat for the breast, an increased crude protein content and chewiness value for the breast, but decreased crude fat content and lower hardness and fracturablility values for the leg quarter. Significantly higher L* values were found for the breast and leg meat of conventionally produced chickens, whereas no significant differences were found for WHC and purge loss between the breast and the leg, and between the two production systems as well. Results of sensory evaluation showed a significant preference for leg over breast meat (p<0.05). The scores of all the attributes including aroma, flavor, firmness, tenderness, juiciness and overall acceptability of leg meat from free-range chickens were slightly higher than for conventional chickens, while the reverse was true for breast meat, though no significant difference could be found. Free-range Taiwan native chicken appeared to yield the best of the results, with flavorful yet tender leg meat for higher sensory satisfaction, and high-protein but low-fat breast meat for healthier diet choice.

Poster Session:PS 0479 ; Nephrology : Hypotonic Versus Isotonic Fluid Maintenance Therapy on Biochemical Outcomes after Major Surgery

( Wei Ying Jen ),( Margaret L Teng ),( Wee Chuan Hing ),( Valerie Ma ),( Shridhar Ganpathi Iyer ),( Chung Cheen Chai ),( Horng Ruey Chua ) 대한내과학회 2014 대한내과학회 추계학술발표논문집 Vol.2014 No.1

Background: Premixed hypotonic solutions of 0.33% saline + 5% dextrose + 10mmol/ L potassium-chloride (0.33S, tonicity 133mEq/L) and 0.9% saline ±dextrose (NS, tonicity 308mEq/L) are common peri-operative maintenance fiuids, but their effects on serum biochemistry are unclear. Methods: Using a single-centre, prospectively-maintained electronic database, we retrospectively examined post-operative biochemistry in adults maintained on exclusively 0.33S or NS peri-operatively, from March 2012 to September 2013. Outcomes included new-onset post-operative hyponatremia, hypokalaemia, hypoglycaemia, and acute kidney injury (AKI, =1.5x increase in serum creatinine); multivariate analyses were adjusted for demographics, comorbidities, surgery-types/duration, infusion time/ volumes, and hospital length-of-stay. Results: We studied 279 patients given 0.33S, and 279 NS controls matched for cumulative infusion volume. Mean age was 59(±18) years. More NS patients had diabetes mellitus, ischemic heart disease and chronic kidney disease (p<0.05). Surgery types included gastrointestinal/hepatobiliary (43%), orthopaedic (30%) and nephrectomy (3%). Mean fi uid volumes administered were 6.9(±3.3)L of 0.33S and 7.1(±5.6)L of NS (p=0.57), with 100% versus 52% of drips containing dextrose, respectively. More 0.33S patients (versus NS) developed hyponatremia (30% versus 17%, p<0.001); this difference was signifi cant for gastrointestinal/hepatobiliary (p=0.001) but not orthopaedic (p=0.74) surgeries. Less 0.33S patients (versus NS) had hypokalaemia (1% versus 10%, p<0.001), hypoglycaemia (1% versus 4%, p=0.01), and AKI (3% versus 8%, p=0.007). On multivariate analyses, 0.33S, gastrointestinal/hepatobiliary surgeries and nephrectomy were independently associated with hyponatremia; while NS, hypertension, longer infusion hours, and nephrectomy were independently associated with AKI (p<0.05). Conclusions: 0.33S infusion in post-surgical patients, especially post-gastrointestinal/ hepatobiliary surgeries, is strongly associated with hyponatremia, but with less hypokalaemia or hypoglycaemia, compared with NS. The association between NS administration and AKI is heavily confounded by baseline comorbidities and requires further prospective evaluation. Both fi uid types are not appropriate for isolated use, and more balanced maintenance fi uids are desired.

Characteristics and survival of ovarian cancer patients treated with neoadjuvant chemotherapy but not undergoing interval debulking surgery

Ying L. Liu,Olga T. Filippova,Qin Zhou,Alexia Iasonos,Dennis S. Chi,Oliver Zivanovic,Yukio Sonoda,Ginger J. Gardner,Vance A. Broach,Roisin E. OCearbhaill,Jason A. Konner,Carol Aghajanian,Kara Long Roc 대한부인종양학회 2020 Journal of Gynecologic Oncology Vol.31 No.1

Objective: Neoadjuvant chemotherapy (NACT) followed by interval debulking surgery (IDS)confers similar outcomes as primary debulking surgery and chemotherapy. Little is knownabout patients who receive NACT but do not undergo debulking surgery. Our aim was tocharacterize these patients. Methods: We prospectively identified patients with newly diagnosed stage III/IV ovariancancer treated with NACT from 7/1/15–12/1/17. Fisher exact and Wilcoxon rank-sum tests wereused to compare clinical characteristics by surgical status. The Kaplan-Meier method wasused to estimate survival outcomes. Log-rank test and Cox proportional hazards model wereapplied to assess the relationship of covariates to outcome, and time-dependent covariateswere applied to variables collected after diagnosis. Results: Of 224 women who received NACT, 162 (72%) underwent IDS and 62 (28%) didnot undergo surgery. The non-surgical group was older (p<0.001), had higher Charlsoncomorbidity index (CCI; p<0.001), lower albumin levels (p=0.007), lower Karnofskyperformance scores (p<0.001), and were more likely to have dose reductions in NACT(p<0.001). Reasons for no surgery included poor response to NACT (39%), death (15%),comorbidities (24%), patient preference (16%), and loss to follow-up (6%). The nosurgery group had significantly worse overall survival (OS) than the surgery group (hazardratio=3.34; 95% confidence interval=1.66–6.72; p<0.001), after adjustment for age, CCI, anddose reductions. Conclusions: A significant proportion of women treated with NACT do not undergo IDS, andthese women are older, frailer, and have worse OS. More studies are needed to find optimaltherapies to maximize outcomes in this high-risk, elderly population.

A GENERALIZATION OF ALZER INEQUALITY RELATED TO EXPONENTIAL FUNCTION

L. Ying,W-Y Cui 장전수학회 2015 Proceedings of the Jangjeon mathematical society Vol.18 No.3

In this paper, we show a generalization of Alzer inequality related to exponential function, and generalize to the remainder of Maclaurin series. Finally, we give an example.

Detailed magnetic structure of Zn1−xNixFe2O4 nanoparticles

Ying, Y.,Eom, T. W.,Lee, Y. P.,Ling, L. S.,Mathe, V. L. American Institute of Physics 2010 JOURNAL OF APPLIED PHYSICS - Vol.108 No.2

Lithium-ion capacitors with 2D Nb₂CT_x (MXene) – carbon nanotube electrodes

Byeon, Ayeong,Glushenkov, Alexey M.,Anasori, Babak,Urbankowski, Patrick,Li, Jingwen,Byles, Bryan W.,Blake, Brian,Van Aken, Katherine L.,Kota, Sankalp,Pomerantseva, Ekaterina,Lee, Jae W.,Chen, Ying,Gog Elsevier 2016 Journal of Power Sources Vol.326 No.-

<P><B>Abstract</B></P> <P>There is a growing interest to hybrid energy storage devices, such as lithium-ion capacitors, in which battery-type electrodes are combined with capacitor-type ones. It is anticipated that the energy density (either gravimetric or volumetric) of lithium-ion capacitors is improved if pseudocapacitive or fast insertion materials are used instead of conventional activated carbon (AC) in the capacitor-type electrode. MXenes, a new family of two-dimensional transition metal carbides, demonstrate metallic conductivity and fast charge-discharge behavior that make them suitable for this application. In this study, we move beyond single electrodes, half-cell studies and demonstrate three types of hybrid cells using Nb<SUB>2</SUB>CT<SUB>x</SUB>–carbon nanotube (CNT) films. It is shown that lithiated graphite/Nb<SUB>2</SUB>CT<SUB>x</SUB>-CNT, Nb<SUB>2</SUB>CT<SUB>x</SUB>-CNT/LiFePO<SUB>4</SUB> and lithiated Nb<SUB>2</SUB>CT<SUB>x</SUB>-CNT/Nb<SUB>2</SUB>CT<SUB>x</SUB>-CNT cells are all able to operate within 3 V voltage windows and deliver capacities of 43, 24 and 36 mAh/g (per total weight of two electrodes), respectively. Moreover, the polarity of the electrodes can be reversed in the symmetric Nb<SUB>2</SUB>CT<SUB>x</SUB>-CNT cells from providing a positive potential between 0 and 3 V to a negative one from −3 to 0 V. It is shown that the volumetric energy density (50–70 Wh/L) of our first-generation devices with MXene electrodes exceeds that of a lithium titanate/AC capacitor.</P> <P><B>Highlights</B></P> <P> <UL> <LI> 3 types of lithium-ion capacitors using Nb<SUB>2</SUB>CT<SUB>x</SUB>-CNT as one electrode were tested. </LI> <LI> The highest volumetric energy density of 50–70 Wh/L was achieved. </LI> <LI> Energy density of symmetric cell exceeds that of lithium titanate/activated carbon. </LI> <LI> The lithiated graphite/Nb<SUB>2</SUB>CT<SUB>x</SUB>-CNT shows the highest gravimetric performance. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Characteristics of registered studies for Coronavirus disease 2019 (COVID-19): a systematic review

Ming Yang,Ya-xi Shang,Zi-yu Tian,Min Xiong,Chun-li Lu,Jiang Yue,Zhang Yao,Zhang Ying-ying,Jin Xin-yan,Jin Qiu-bai,Zhang Ying-ying,Willcox Merlin L.,Liu Jian-ping 한국한의학연구원 2020 Integrative Medicine Research Vol.9 No.3

Background: The World Health Organization characterized the Coronavirus disease 2019 (COVID-19) as a pandemic on March 11th. Many clinical trials on COVID-19 have been registered, and we aim to review the study characteristics and provide guidance for future trials to avoid duplicated effort. Methods: Studies on COVID-19 registered before March 3rd, 2020 on eight registry platforms worldwide were searched and the data of design, participants, interventions, and outcomes were extracted and analyzed. Results: Three hundred and ninety-three studies were identified and 380 (96.7%) were from mainland China, while 3 in Japan, 3 in France, 2 in the US, and 3 were international collaborative studies. Two hundred and sixty-six (67.7%) aimed at therapeutic effect, others were for prevention, diagnosis, prognosis, etc. Two hundred and two studies (51.4%) were randomized controlled trials. Two third of therapeutic studies tested Western medicines including antiviral drugs (17.7%), stem cell and cord blood therapy (10.2%), chloroquine and derivatives (8.3%), 16 (6.0%) on Chinese medicines, and 73 (27.4%) on integrated therapy of Western and Chinese medicines. Thirty-one studies among 266 therapeutic studies (11.7%) used mortality as primary outcome, while the most designed secondary outcomes were symptoms and signs (47.0%). Half of the studies (45.5%) had not started recruiting till March 3rd. Conclusion: Inappropriate outcome setting, delayed recruitment and insufficient numbers of new cases in China implied many studies may fail to complete. Strategies and protocols of the studies with robust and rapid data sharing are warranted for emergency public health events, helping the timely evidence-based decision-making.

<i>DLEC1</i> is a functional 3p22.3 tumour suppressor silenced by promoter CpG methylation in colon and gastric cancers

Ying, J,Poon, F F,Yu, J,Geng, H,Wong, A H Y,Qiu, G-H,Goh, H K,Rha, S Y,Tian, L,Chan, A T C,Sung, J J Y,Tao, Q Nature Publishing Group 2009 The British journal of cancer Vol.100 No.4

<P>Promoter CpG methylation of tumour suppressor genes (TSGs) is an epigenetic biomarker for TSG identification and molecular diagnosis. We screened genome wide for novel methylated genes through methylation subtraction of a genetic demethylation model of colon cancer (double knockout of <I>DNMT1</I> and <I>DNMT3B</I> in HCT116) and identified <I>DLEC1</I> (Deleted in lung and oesophageal cancer 1), a major 3p22.3 TSG, as one of the methylated targets. We further found that <I>DLEC1</I> was downregulated or silenced in most colorectal and gastric cell lines due to promoter methylation, whereas broadly expressed in normal tissues including colon and stomach, and unmethylated in expressing cell lines and immortalised normal colon epithelial cells. <I>DLEC1</I> expression was reactivated through pharmacologic or genetic demethylation, indicating a DNMT1/DNMT3B-mediated methylation silencing. Aberrant methylation was further detected in primary colorectal (10 out of 34, 29%) and gastric tumours (30 out of 89, 34%), but seldom in paired normal colon (0 out of 17) and gastric (1 out of 20, 5%) samples. No correlation between <I>DLEC1</I> methylation and clinical parameters of gastric cancers was found. Ectopic expression of <I>DLEC1</I> in silenced HCT116 and MKN45 cells strongly inhibited their clonogenicity. Thus, <I>DLEC1</I> is a functional tumour suppressor, being frequently silenced by epigenetic mechanism in gastrointestinal tumours.</P>

The Safety and Efficacy of a Dietary Herbal Supplement and Gallic Acid for Weight Loss

Frank L. Greenway,Andrew T. Roberts,Corby K. Martin,Zhijun Liu,Ronald J. Amen,Eugene A. Woltering,Jennifer C. Rood,Mary K. Caruso,Ying Yu,Hui Xie 한국식품영양과학회 2007 Journal of medicinal food Vol.10 No.1

The objective of this study was to test the safety and efficacy of NT, a dietary herbal supplement made fromrhubarb, ginger, astragulus, red sage, and turmeric, combined with gallic acid (GA) to reduce food intake and cause weightloss. A total of 105 healthy subjects, 1860 years old with a body mass index of 2535 kg/m2 and on no chronic medication,were randomized to a 300 mg/1.2 g NT-GA combination, a 600 mg/2.4 g NT-GA combination, or placebo in three divideddoses daily for 24 weeks. Food intake was measured at baseline and 2 weeks, and safety parameters were followed regularly.Pharmacokinetic studies of a 200 mg/800 mg NT-GA combination and 800 g GA alone were performed with and withoutfood. There was no dose-related weight loss or reduction in food intake at the 8-week analysis, and the study was terminatedearly. Pharmacokinetic studies showed plasma levels of GA did not increase above 10 .M and were not dose-related. TheNT-GA at all concentrations was well tolerated, but was ineffective in causing weight loss or in suppressing food intake. Phar-macokinetics suggested that GA plasma levels were limited by oral absorption, and may be the reason for lack of efficacy.