간호대생과 의대생의 간호사 이미지 비교

구민진,김수영,방정민,서아영,양희진,윤소람,이윤재,이재은,이지연,정윤경,최수정 이화여자대학교 간호과학대학 2014 이화간호학회지 Vol.- No.48

Purpose: This study aims to analyze the difference in the perception that nursing students and medical students have regarding the image of nurses. Method: The sampling group for this study was made up of 111 nursing students and 117 medicine students, conducted from the 19th August 2013 to 3rd September 2013. The tool used for this study is the “Nurse Image Scale”. The data is analyzed using the SPSS 21.0 program, technical stats, t-test and ANOVA with Scheffe test. Result: There was a notable difference in the results(t=6.94, p<001), with the average image perception score of nurses at 3.84±0.34 amongst nursing students being higher than the 3.50±0.38 amongst Medicine students. The average score of the 4 areas tested, “Qualification of a Nurse”, “Role of a Nurse”, “Social Participation of a Nurse” and “Interpersonal Skills of a Nurse” were all marked higher by the nursing students than the medicine students. The average score became notably higher as the period of practice became shorter with nursing students (F=4.21, p=.043). Furthermore, the average score for the “Qualification of a Nurse” was notably higher as the period of practice became shorter (F=3.98, p=.049). Medical students gave an average score for the “Qualification of a Nurse”(F=3.72, p=.027) and the “Interpersonal Skills of a Nurse”(F=4.11, p=.019) which was relative to the development of a nurse’s image, while the average score for the “Role of a Nurse” was notably higher with a longer period of practice(F=6.65, p=.011). Conclusion: The results of this study suggest that the image perception of a nurse can vary depending on the experience in period of practice. Therefore, together with this study conducted with nursing students and medicine students, there is a need for further studies conducted on image perception of nurses with various experience in period of practice.

P183 : MicroRNA-1290 mediated cellular mechanism promotes asiatic acid induced apoptosis is in a549 non small cell lung carcinoma cells

( Ho Jung Jung ),( Min Jung Kim ),( Hae Jeong Youn ),( Nam Kyung Roh ),( Soo Young Kim ),( Yu Ri Kim ),( Yu Na Lee ),( Jae Wook Jung ),( Yang Won Lee ),( Yong Beom Choe ),( Kyu Joong Ahn ),( In Sook A 대한피부과학회 2014 대한피부과학회 학술발표대회집 Vol.66 No.2

Background: Asiatic acid is a putative anticancer agent in several types of cancer cells. Researches of its biological role in negative regulation of cell growth have focused on the extent of induction of apoptosis in a cell-type-specific manner. Objectives: To identify the mechanisms underlying asiatic acid-induced downregulation of BCL2. Methods: MicroRNA microarray analysis was used to investigate the effect of asiatic acid treatment of A549 cells on miRNA expression profiles. We used quantitative RT-PCR to confirm the asiatic acid-induced increase in miR-1290 level with primers specific for the mature miR-1290 sequence. We also assessed the effect of asiatic acid on the levels of BCL2 in A549 cells using western blot analysis. Results: We identified an important regulator of asiatic acid-induced cell death, microRNA (miR)-1290, which sensitizes cells to Asiatic acid-induced cytotoxicity and negatively regulates BCL2 expression. Asiatic acid significantly upregulated miR-1290, and asiatic acid-induced cell death was shown to be dependent on miR-1290 activity. Molecular assays demonstrated that BCL2 mRNA is a direct target of miR-1290-mediated RNA interference. Conclusion: The findings of the present study suggest that miR-1290 suppresses cell viability and cell cycle progression. Our results provide insight into miR-1290-mediated cellular mechanisms in asiatic acid-treated A549 non-small cell lung carcinoma cells.

CMOS Transistors with a 70-nm Gate Length for 0.13-μm-Node High-Performance Applications

Kyoung-Seok Rha,Dong-Hun Lee,Eun-Seung Jung,Hae-Kyung Kong,Hyae-Ryoung Lee,Jeong-Ho Lyu,Jeong-Hwan Yang,Jin-Suk Jung,Jung-A Choi,Kwang-Pyuk Suh,Young-Wug Kim 한국물리학회 2004 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.44 No.1

Conventional CMOS transistors for high performance with a 70-nm physical gate length were fabricated to evaluate the 130-nm-technology node. In this work, we enhanced the performance of transistors by using high-dose P+ implantation, a plasma-nitridation gas oxide, a hydrogen prebake (HPB), and a mechanical stress layer. We also reduced the overlap capacitances by using an oset spacer. The NMOS and PMOS have drive currents equal to 880 A/m and 420 A/m, respectively, with Ioff = 10 nA/m at Vdd = 1.2 V. The unit delay of the ring oscillator (1 fan-out) was 11.5 ps.

20대여성의 유방자가검진에 대한 지식과 자기효능감의 관계연구

강지혜,유리나,박민아,박신영,양은주,이주은,전시은,정윤혜,최연아,홍재하,이자형,정덕유,배노연 이화여자대학교 간호과학대학 2009 이화간호학회지 Vol.- No.43

The purpose of this study was to know relationship between important variables which influence lifestyle in college women`s health promotion, prove adjustable factors and provide basic data which develops nursing intervention health promotion program. The method of this study was descriptive correlational study. The convenience sample was 206 college woman who live alone in lodgings, dormitory, a reading room or off-campus housing. Research instruments were the Multidimensional Health Locus of Control(MHLC) developed by Wallston, Wallston & Devellis(1978), Interpersonal Support Evaluation List developed by Cohern, Hoberman(1983) and The Health Promotion Lifestyle Profile(HPLP) developed by Walker, Pender & Sechrist(1978) and the data was used after Factor Analysis. The result of this study was follows. 1. It can be found that the level of the college woman`s health promotion lifestyle was 2.46±.33 with higher fulfilling level: According to general characteristic, the level of health promotion lifestyle was 5% significant statistical differences by age and period of menstruation. 2. The level of health locus of control was 3.25±.31 with higher fulfilling level. 3. The interpersonal support level was 3.05±.44 with higher fulfilling level. 4. The level of interpersonal support turned out most convincing factor in health promotion lifestyle (9%). In addition to age factor, two factors was 10% power of explanation in whole health promotion.

Biological controls of Franklinella occidentalis by Amblyseius swirskii and Neoseiulus cucumeris to greenhouse grown lettuce in summer season

Jae-A Jung,Hyeong-Hwan Kim,Taek-Jun Kang,Myoung-Rae Cho,Heung-Yong Jeon,Chang-Yeul Yang 한국응용곤충학회 2010 한국응용곤충학회 학술대회논문집 Vol.2010 No.10

Lettuce was a leaf vegetable with short growing term and cold-tolerant plant. We grew it the whole year. The price of lettuce is the most expensive from July to September. But damages by lots of insect pests appear to greenhouse grown lettuce in summer season. In this study, we observed biological controls of western flower thrips(Franklinella occidentalisi) by the predator mites, Amblyseius swirskii and Neoseiulus cucumeris in lettuce greenhouse from July 7 to September 10. Hypoaspis aculerfer larvae and adults were released 30 individuals per m2 at the first one time as lettuce was planted on the greenhouse. We checked the density of F. occidentalis every 10 days on the 30 lettuce leaves. When the population of F. occidentalis reached 1~5 individuals per a leaf, A. swirskii larvae and adults were released 35 individuals per m2 at 1~3 times and Neoseiulus cucumeris larvae and adults also were released 150 individuals per m2 at 2~3 times in each lettuce greenhouse. During the high temperature season, Amblyseius swirskii was more effective biological controls of F. occidentalis than Neoseiulus cucumeris.

한부모 가정 초등학생을 위한 자아존중감 향상 프로그램의 효과

정선아(Sun-A Jung),하양숙(Yang-Sook Hah) 한국콘텐츠학회 2013 한국콘텐츠학회논문지 Vol.13 No.9

본 연구는 자아존중감 향상 프로그램이 한부모 가정 초등학생의 자아존중감과 우울에 미치는 효과를 검증하기 위해 실시되었다. 연구에 참여한 대상자들은 본 프로그램에 동의한 두 개의 초등학교 한부모 가정아동 중 지원자를 받아 A학교를 실험군(12명)으로, B학교를 대조군(13명)으로 임의 배정하고 프로그램 시작 전에 자아존중감과 우울 척도를 이용하여 사전 검사를 실시하였다. 실험군에게는 한부모 가정 초등학생을 위한 자아존감향상 프로그램을 제공하였다. 실험처치는 실험군 12명을 6명씩 2집단으로 나누어 주 1회 40분씩 총 10회기를 진행하였다. 프로그램 종료 후 실험군, 대조군에게 자존감과 우울 척도를 이용하여 사후 검사를 실시하였다. 사후 검사에서 실험군 1명의 자료가 결측되어 최종 실험군 11명, 대조군 13명의 자료가 수집되었다. 연구결과 대조군 보다 실험군이 유의한 수준에서 자아존중감이 증가(z=-2.499, p<.012, ES(d)=0.7)하고, 우울이 감소(z=-2.145, p<.032, ES(d)=-0.4) 되었다. 이러한 결과는 본 연구의 프로그램이 한부모 가정 초등학생들의 심리사회적 적응을 위해 유용하게 사용될 수 있음을 시사한다. This study aims to testify the effect of self-esteem improvement program for elementary school children from single-parent families on their self-esteem and depression. Methods: The research design used in this study was a non-equivalent control group pretest-posttest research design. The participants were divided into two groups, an experimental group(n=11) and a control group(n=13). Data were analysed by using Mann-Whinety U test, Wilcoxon Signed Ranks, Cohen’s d with SPSS(PASW)18.0 program. Result: Significant differences were found in scores for self-esteem(z=-2.499, p<.012, ES(d)=0.7) and depression(z=-2.145, p<.032, ES(d)=-0.4) in experimental group. Conclusion: The results indicate that the self-esteem improvement program should be used with elementary school children from single-parent families to help them and to improve their psycho-social adaptation.

8년간(1992~1999) 산업안전보건연구원에 의뢰된 직업병 심의 사례 분석

강성규,김규상,김양호,최정근,안연순,진영우,최병순,양정선,김은아,채창호,최용휴,김대성,박정선,정호근 대한산업의학회 2000 대한직업환경의학회지 Vol.12 No.2

Objectives : Pneumoconisis and noise-induced hearing loss (NIHL) have been reported as main occupational diseases by the Special Health Examination. The Industrial Accident Compensation Insurance has reported various work-related diseases, however, these two diseases occupied almost a half of compensated cases. Therefore, it was not well known about the status of occupational diseases other than pneumoconiosis, NIHL, and cardio-cerebrovascular accident (CVA). This study was conducted to analyze claimed cases as an occupational disease, that was requested to the Korea Industrial Safety and Health Agency (KOSHA). Methods : The local office of the Korea Labor Welfare Corporation (KLWC) has asked the KOSHA for confirmation of claimed cases as an occupational disease. We analyzed 379 cases requested from KLWC, the Ministry of Labor, employers, unions and occupational health agencies from 1992 to 1999. Results : Male was 80.7 % of the requested cases. Their mean age was 42 years old and 75.5 % of them were more than 35 years old. The requested cases were increased rapidly from 25 cases in 1992 to 108 cases in 1999 and the accept rate was 50.7 %. The majority of requested cases were respiratory diseases(22.4%), cancers(18.5%), Neuropsychiatric problems(14.5%), and musculoskeletal problems(13.5%). The accept rate was high in reproductive, respiratory, musculoskeletal and digestive disorders and low in neuropsychiatric, renal and otologic problems and occupational cancers. 73.6% of them were caused by chemical agents, especially 28.5 % were by organic solvents. 67% of them were clinically confirmed at university hospitals. A half of the cases were from KyongIn area, even the request came from the whole country. Conclusions : A claim was common in workers whose age was over 35 years old and exposure history was over 10 years. The respiratory diseases and neuropsychiatric disorders were still main problems in occupational health and occupational cancers was increasing even though its accept rate was not high yet.

The Influence of Feed Energy Density and a Formulated Additive on Rumen and Rectal Temperature in Hanwoo Steers

Cho, Sangbuem,Mbiriri, David Tinotenda,Shim, Kwanseob,Lee, A-Leum,Oh, Seong-Jin,Yang, Jinho,Ryu, Chaehwa,Kim, Young-Hoon,Seo, Kang-Seok,Chae, Jung-Il,Oh, Young Kyoon,Choi, Nag-Jin Asian Australasian Association of Animal Productio 2014 Animal Bioscience Vol.27 No.11

The present study investigated the optimum blending condition of protected fat, choline and yeast culture for lowering of rumen temperature. The Box Benken experimental design, a fractional factorial arrangement, and response surface methodology were employed. The optimum blending condition was determined using the rumen simulated in vitro fermentation. An additive formulated on the optimum condition contained 50% of protected fat, 25% of yeast culture, 5% of choline, 7% of organic zinc, 6.5% of cinnamon, and 6.5% of stevioside. The feed additive was supplemented at a rate of 0.1% of diet (orchard grass:concentrate, 3:7) and compared with a control which had no additive. The treatment resulted in lower volatile fatty acid (VFA) concentration and biogas than the control. To investigate the effect of the optimized additive and feed energy levels on rumen and rectal temperatures, four rumen cannulated Hanwoo (Korean native beef breed) steers were in a $4{\times}4$ Latin square design. Energy levels were varied to low and high by altering the ratio of forage to concentrate in diet: low energy (6:4) and high energy (4:6). The additive was added at a rate of 0.1% of the diet. The following parameters were measured; feed intake, rumen and rectal temperatures, ruminal pH and VFA concentration. This study was conducted in an environmentally controlled house with temperature set at $30^{\circ}C$ and relative humidity levels of 70%. Steers were housed individually in raised crates to facilitate collection of urine and feces. The adaptation period was for 14 days, 2 days for sampling and 7 days for resting the animals. The additive significantly reduced both rumen (p<0.01) and rectal temperatures (p<0.001) without depressed feed intake. There were interactions (p<0.01) between energy level and additive on ruminal temperature. Neither additive nor energy level had an effect on total VFA concentration. The additive however, significantly increased (p<0.01) propionate and subsequently had lower acetate:propionate (A/P) ratios than non-additive supplementation. High concentrate diets had significantly lower pH. Interactions between energy and additive were observed (p<0.01) in ammonia nitrogen production. Supplementation of diets with the additive resulted in lower rumen and rectal temperatures, hence the additive showed promise in alleviating undesirable effects of heat stress in cattle.

In silico-Selection of Brassica rapa Organelle Genome-Derived BACs Using Their End Sequences and Sequence Level Comparative Analysis of the 124 kb Mitochondrial Genome Sequences in the Family Brassicaceae

Park, Jee-Young,Kwon, Soo-Jin,Choi, Beom-Soon,Lim, Ki-Byung,Hwang, Yoon-Jung,Kim, Jin-A,Lim, Yong-Pyo,Park, Beom-Seok,Yang, Tae-Jin 한국작물학회 2009 Journal of crop science and biotechnology Vol.12 No.4

We identified BAC clones which harbor DNAs derived from the B. rapa organelle genomes by in silico mapping of 80,292 B. rapa BAC end sequences on the Arabidopsis organelle genomes and subsequent insert size estimation and fingerprinting. A total of 1,048 putative chloroplast genome-derived BAC clones (2.6%) were identified. Fingerprinting and sequencing revealed that many of them represented the entire chloroplast genome (about 150 kb). Meanwhile, only 59 putative mitochondrial genome-derived BACs (0.15%) were identified and most of them showed rare agreement between the in silico map and fingerprinting. We sequenced BAC clone KBrB042G11 (42G11) and compared it to the mitochondrial genome of B. napus and A. thaliana which showed dynamic rearrangement events. The order of 33 orthologous genes was collinear between the 42G11 BAC and its counterpart in B. napus. Five distinctive rearrangements and two InDels were identified between these two closely related species and the rearrangements were related to the occurrence of small tandem repeat sequences. Sequences of the 33 orthologous genes in the homoeologous regions of B. napus and B. rapa were almost 100% identical. Gene orders showed no colinearity between Arabidopsis and Brassica even though 31 orthologous genes shared high sequence similarity with p-values over 1E-32. FISH analysis using the identified BAC revealed a large chloroplast genome insertion in the pericentromeric region of chromosome (chr.) 4 of B. rapa.

소아의 급성 인두염에서 연쇄구균 신속항원검사의 유용성

임기현 ( Ki Hyun Lim ),최우진 ( Woo Jin Choi ),김미진 ( Mi Jin Kim ),김영호 ( Young Ho Kim ),정지아 ( Ji A Jung ),양승 ( Seung Yang ),황일태 ( Il Tae Hwang ),이혜란 ( Hae Ran Lee ) 대한소아알레르기호흡기학회(구 대한소아알레르기 및 호흡기학회) 2006 소아알레르기 및 호흡기학회지 Vol.16 No.1

목 적 : 최근 소아 급성 인두염에서 부적절한 항생제 투여가 문제시 되고 있으나 증상만으로 항생제 사용 여부를 결정하기는 어려우며 인두배양검사가 확진 방법이다. 그러나 검사에 시간이 요구되므로 미국소아과학회에서는 배양검사와 신속항원검사를 시행하여 신속항원검사가 음성이면 항생제 사용을 보류하도록 권하고 있다. 저자들은 이와 같은 지침을 국내에서도 적용할 수 있는지 알아보고자 연쇄구균 신속항원검사의 유용성을 조사하였다. 방 법 : 2004년 9월부터 2005년 8월까지 한림대학교 강동성심병원 소아과를 방문하여 급성 인두염으로 진단받은 70명을 대상으로 하였다. 편도 삼출, 발열, 피부 발진 등의 임상적 특징과 내원 전 항생제 투여 여부를 조사하고, CBC, ASO, CRP 등의 혈액 검사와 인두에서 연쇄구균 신속항원검사와 배양검사를 시행하였다. 결 과 : 1) 인두배양검사에서 A군 연쇄구균이 분리된 양성례는 14례(20.0%)이었으며, 연쇄구균 신속항원검사는 22례(31.4%)에서 양성이었다. 인두배양검사에 대한 신속항원검사의 민감도는 78.6 %, 특이도는 80.4%이었다. 양성예측치는 50.0%, 음성예측치는 93.8%이었다. 2) 발열 유무에 따라 인두배양검사와 신속항원검사에는 차이가 없었다. 3) 편도삼출의 여부에 따라 인두배양검사 양성률에 차이가 없었으며, 신속항원검사는 오히려 편도삼출이 없는 경우에서 양성이 더 많았다. 4) 성홍열양 발진이 있는 경우에 인두배양검사와 신속항원검사에서 양성이 많았다. 5) 인두배양검사 양성은 항생제를 이전에 투여한 경우에 35례 중 3례(8.57%) 이전에 항생제를 투여하지 않은 경우의 35례 중 11례(31.43%)로 낮아 항생제 사용이 인두배양검사에 영향을 주었다. 이전에 인두배양검사는 양서d음성이어도 신속항원검사는 양성인 경향이 있었다. 6) 인두배양검사와 신속항원검사에 따라 혈액의 백혈구 수, ASO, CRP 값은 각각 통계학적인 차이가 없었다. 결 론 : 소아 급성 인두염에서 신속항원검사는 연쇄구균 감염의 진단에 유용한 도구로서 항생제의 조기 투여 여부를 결정하는 데 도움이 되리라 사료된다. Purpose : The purpose of this study was to evaluate the utility of rapid antigen detection test for group A streptococci in children with acute pharyngitis. Methods : Seventy children with acute pharyngitis enrolled the study, who visited the Department of Pediatrics, Kangdong Sacred Heart Hospital, Hallym Medical Center from September 2004 to August 2005. The presence of clinical features such as tonsillar exudates, fever, scarletiniform rash and previous antibiotic use were evaluated and throat swab culture, rapid antigen detection test for group A Streptococci, CBC, ASO, and CRP were performed. Results : Among 70 children with acute pharyngitis, the prevalence of group A beta-hemolytic Streptococcus by throat swab culture and rapid antigen detection test was 14(20.0 %) and 22(31.4%), respectively. The sensitivity of the rapid antigen detection test was 78.6 %, specificity was 80.4%, the positive predictive value was 50.0% and the negative predictive value was 93.8%. The positivity of the throat swab culture and rapid antigen detection test showed no signigicant differences according to the presence of the clinical symptoms except scarletiniform rash. Laboratory data such as CBC, ASO or CRP proved not valuable to predict the positivity of the throat swab culture and/or rapid antigen detection test for group A Streptococcus. There was a tendency of negative throat swab culture and positive rapid antigen detection test in cases of previous antibiotic use. Conclusion : The rapid antigen detection test can be a useful diagnostic tool for early detection of the group A Streptococcus in children with acute pharyngitis and can be helpful for the clinician to reduce the inappropriate use of antibiotics. [Pediatr Allergy Respir Dis (Korea) 2006;16:57-65]